Tag: M.W=150-200

Ghayalkar, Renu B. published the artcileSynthesis and antimicrobial activity of N-glucosylated derivatives of thiadiazolidines, Related Products of chlorides-buliding-blocks, the publication is Indian Journal of Heterocyclic Chemistry (2014), 23(3), 257-260, database is CAplus.

A series of new 1-(3-arylimino-4-aryl-5-imino-1,2,4-thiadiazolidines)-3-tetra-O-benzoyl-β-D-glucosyl carbamides, e.g. I, were synthesized by the interaction of tetra-O-benzoyl-β-D-glucosyl isocyanate with 3-arylimino-4-aryl-5-imino-1,2,4-thiadiazolidines. The identities of these newly synthesized N-glucosylated thiadiazolidine carbamides have been established on the basis of usual chem. transformations and IR, ¹H NMR and Mass spectral studies. These compounds were screened for their antibacterial activity and antifungal activity against some selected pathogenic organisms to get potent bioactive mol.

Indian Journal of Heterocyclic Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Karhe, Usha W. published the artcileSynthesis of some biologically important per-O-benzoyl maltosyl isothiocarbamides and isodithiobiurets as antibacterial and antifungal agents, Computed Properties of 3696-23-9, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2014), 53B(2), 212-217, database is CAplus.

Several S-hepta-O-benzoyl maltosyl-1-arylisothiocarbamides have been synthesized through several steps viz. benzoylation, bromination and interaction of hepta-O-benzoyl maltosyl bromide with aryl thiocarbamides. S-Hepta-O-benzoyl maltosyl-1-aryl-5-phenyl-2,4-isodithiobiurets have been synthesized by the interaction of S-hepta-O-benzoyl maltosyl-1-arylisothiocarbamides with Ph isothiocyanate. All new compounds have been characterized by spectral anal. such as IR, ¹H NMR and mass spectra as well as elemental anal. and in-vitro antimicrobial activity of maltosyl isothiocarbamides and related isodithiobiurets has been evaluated against several human pathogens. Out of 12 compounds prepared and screened, four compounds have shown significant activity against different human pathogens.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Computed Properties of 3696-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zade, Varsha S. published the artcileSynthesis and characterization of per-acetylated S-maltosyl 2-isothiobiurets and 2,4-isodithiobiurets and their in vitro antimicrobial activity, Synthetic Route of 3696-23-9, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2015), 54B(6), 815-820, database is CAplus.

A series of S-hepta-O-acetyl-maltosyl-1-aryl-5-p-tolyl-2-isothio-biurets, S-hepta-O-acetyl-maltosyl-1-aryl-5-p-chloro-phenyl-2-isothio-biurets and S-hepta-O-acetyl maltosyl-1-aryl-5-p-tolyl-2,4-isodithio-biurets have been synthesized by the interaction of various S-hepta-O-acetyl maltosyl-1-aryl isothiocarbamides with p-tolyl isocyanate, p-chloro-Ph isocyanate and p-tolyl isothiocyanate resp. The required maltosyl arylisothiocarbamides are synthesized by the displacement of anomeric bromide of acetobromomaltose with aryl thiocarbamides. The identities of these newly synthesized thiomaltosides have been established on the basis of chem. transformations and IR, mass, 1H and 13C NMR spectral studies. These compounds have been screened for their antibacterial and antifungal activities against E. coli, S. aureus, Ps. aeruginosa, S. typhi, R. oligosporus and A. niger. These compounds show most promising activity towards these micro-organisms.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H4BrClO2, Synthetic Route of 3696-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zade, Varsha S. published the artcileSynthesis and biological evaluation of S-maltosylated 1,2,4-thiadiazoline derivatives against human pathogens, Safety of 1-(4-Chlorophenyl)thiourea, the publication is Indian Journal of Heterocyclic Chemistry (2014), 24(2), 163-166, database is CAplus.

A series of new 4-aryl-5-p-tolylimino-3-S-hepta-O-acetyl maltosyl-1,2,4-thiadiazolines, e.g. I, were synthesized by the interaction of N-p-tolyl-S-chloro isothiocarbamoyl chloride with S-hepta-O-acetyl maltosyl-1-aryl isothiocarbamides. These compounds were screened for their antibacterial and antifungal activities against E. coli, S. aureus, P. aerUginosa, S. typhi, R. oligospora and A. niger. The identities of these newly synthesized thiomaltosides have been established on the basis of chem. transformations and IR, 1H NMR and mass spectral studies. These compounds show most significant activity towards these micro-organisms.

Indian Journal of Heterocyclic Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H4BrClO2, Safety of 1-(4-Chlorophenyl)thiourea.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Lindemann, Marcel published the artcileDo spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter?, Computed Properties of 6313-54-8, the publication is Bioorganic & Medicinal Chemistry (2017), 25(19), 5107-5113, database is CAplus and MEDLINE.

The vesicular acetylcholine transporter (VAChT) is an important target for in vivo imaging of neurodegenerative processes using positron emission tomog. (PET). So far the development of VAChT PET radioligands is based on the single known lead compound vesamicol. In this study we investigated a recently published spiroindoline based compound class (Sluder et al., 2012), which was suggested to have potential in the development of VAChT ligands. Therefore, we synthesized a small series of N,N-substituted spiro[indoline-3,4′-piperidine] derivatives and determined their in vitro binding affinities toward the VAChT. In order to investigate the selectivity, the off-target binding toward σ₁ and σ₂ receptors was determined The compounds possessed VAChT affinities with K_i values in the range of 39-376 nM. Binding affinities toward the σ₁ and σ₂ receptors are in a similar range indicating that the strong structural difference between the spiroindolines and vesamicol did not improve the selectivity. The observed potential to addnl. bind to σ receptors let us assume that the herein investigated spiroindolines are not suitable to replace vesamicol as lead compound for the development of VAChT ligands.

Bioorganic & Medicinal Chemistry published new progress about 6313-54-8. 6313-54-8 belongs to chlorides-buliding-blocks, auxiliary class Pyridine,Chloride,Carboxylic acid, name is 2-Chloroisonicotinic acid, and the molecular formula is C6H4ClNO2, Computed Properties of 6313-54-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Raju, D. Nooka published the artcileSynthesis, characterization and analgesic activity of some novel substituted 2-amino benzothiazole derivatives, Formula: C7H7ClN2S, the publication is World Journal of Pharmacy and Pharmaceutical Sciences (2015), 4(5), 1815-1821, database is CAplus.

The synthesis of some novel substituted 2-amino benzothiazoles I (R = 6-Cl, 6-Br, 6-NO₂, 6-COOH) is described. The synthesized compounds were screened for analgesic activity. Compounds I (R = 6-Cl, 6-NO₂) have highly significant analgesic activity with reference to the standard aspirin and consequently further exploration of these benzothiazole derivatives should make these mols. accessible for widespread use as potent analgesic agents.

World Journal of Pharmacy and Pharmaceutical Sciences published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Formula: C7H7ClN2S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sharma, Praveen Kumar published the artcileSynthesis and antimicrobial activities of substituted phenylthioureas, Recommanded Product: 1-(4-Chlorophenyl)thiourea, the publication is Journal of Chemical and Pharmaceutical Research (2015), 7(2), 133-139, database is CAplus.

The synthesis of substituted phenylthioureas is reported. All the synthesized compounds were screened for their antimicrobial activities. These compounds were found to have antimicrobial activities comparable to and in some cases greater than those of equimolar quantities of standard drug.

Journal of Chemical and Pharmaceutical Research published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C9H4F6O, Recommanded Product: 1-(4-Chlorophenyl)thiourea.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Labande, Agnes published the artcileRhodium(III) and ruthenium(II) complexes of redox-active, chelating N-heterocyclic carbene/thioether ligands, Product Details of C4H8Cl2S2, the publication is New Journal of Chemistry (2011), 35(10), 2162-2168, database is CAplus.

Half-sandwich rhodium(III) and ruthenium(II) complexes bearing a new redox-active ferrocenyl NHC-thioether ligand have been prepared The synthesis of ferrocenyl thioether-imidazolium salts was carried out via intermediate FcSCH₂CH₂Cl using an improved procedure. Rhodium(III) complex and ruthenium(II) complex were obtained in good yields and were fully characterised by NMR spectroscopy, x-ray diffraction anal. and electrochem. Rhodium(III) complex shows a complex ABCD system by ¹H NMR, which denotes conformational rigidity due to the presence of several bulky groups. Electrochem. anal. by cyclic voltammetry reveals reversible redox behavior about the iron center in both complexes, and indicates electronic communication between iron and rhodium or ruthenium.

New Journal of Chemistry published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Product Details of C4H8Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Tan, Guangying published the artcileRhodium-Catalyzed Dealkenylative Arylation of Alkenes with Arylboronic Compounds, SDS of cas: 145349-62-8, the publication is Angewandte Chemie, International Edition (2021), 60(28), 15650-15655, database is CAplus and MEDLINE.

Herein, the first example of rhodium-catalyzed dealkenylative arylation of alkenes with arylboronic compounds, thereby providing an unconventional access to biaryls with excellent chemoselectivity was diclosed. In this method, C(aryl)-C(alkenyl) and C(alkenyl)-C(alkenyl) bonds in various alkenes and 1,3-dienes could be cleaved via a hydrometalation and followed by β-carbon elimination pathway for Suzuki-Miyaura reactions. Furthermore, a series of novel organic fluorescent mols. with excellent photophys. properties were efficiently constructed with this protocol.

Angewandte Chemie, International Edition published new progress about 145349-62-8. 145349-62-8 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids, name is 2-Chloro-4-methylphenylboronic acid, and the molecular formula is C6H4KNO6S, SDS of cas: 145349-62-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Verma, M. R. published the artcileA paper-chromatographic method for the identification of 1- and 2-naphthols when present together, Synthetic Route of 6249-56-5, the publication is Journal of Chromatography (1960), 197-9, database is CAplus.

1-Naphthol (I) and 2-naphthol (II) dissolved in alc., spotted on filter paper, and coupled in situ with cold alk. 0.2M di azotized di-Na 2-naphthylamine-5,7-disulfonate gave the following R_f values, resp., with several eluants: iso-AmOH-EtOH-NH₄OH (40:40:25) 0.14, 0.28; iso-AmOH-EtOH-H₂O (40:40:25) 0.10, 0.24; iso-BuCOMe-EtOH (70:30) saturated with 10% NH₃ 0.04, 0.18. Rose-red spots were formed with both I and II in each eluant.

Journal of Chromatography published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C9H8O4, Synthetic Route of 6249-56-5.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics