Tag: M.W=150-200

Mushtaq, Nafeesa; Chen, Guofei; Sidra, Lala Rukh; Zhang, Anjiang; Fang, Xingzhong published the artcile< Kinetic Studies of Bischloroimide Monomers for the Facile Synthesis of Different Molecular Architecture Poly(phthalimide-co-naphthalimide)s>, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione, the main research area is polyphthalimide naphthalimide bischloroimide kinetics thermal mech property.

A series of different mol. architecture (homo, random, block and gradient type) copolymers PI-3(a-e) were synthesized by solution polycondensation. Three different bischloroimide monomers [bischlorophthalimide 2a, bischloronaphthalimide 2b and bischloro (naphthalimide-phthalimide) 2c] were prepared and reacted with 4,4′-thiobisbenzenethiol by different synthetic routes. The chem. reactivity of these monomers 2(a-c) was examined by kinetic study of model compounds N-phenyl-4-chloro-1,8-naphthalimide and N-phenyl-4-chlorophthalimide using gas chromatog. mass spectrometry (GC-MS). The difference in chem. reactivity of monomers was utilized to design mol. architecture of copolymer, and the influence of comonomers sequence on copolymer properties is investigated. The synthesized copolyimides PI-3(a-e) integrated the excellent properties of naphthalimide and phthalimide as good organosoly., high glass transition temperature of 198-319°C and good thermooxidative stability based on 5% weight loss temperature of 492-524°C and 480-532°C in nitrogen and air, resp. Gradient type sequence PI-3 e offers a good combination of phthalimide and naphthalimide groups in copolymers for improved thermal and mech. properties.

ChemistrySelect published new progress about Absorption (water). 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Recommanded Product: 5-Chloroisobenzofuran-1,3-dione.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Qian; Zhao, Xiaoqian; Xu, Feng; Li, Gaoqiang published the artcile< Metal-free oxidative coupling of alkyl chlorides with thiols: An efficient access to sulfoxides>, Computed Properties of 611-19-8, the main research area is aromatic sulfoxide preparation; aralkyl chloride aromatic thiol oxidative coupling.

An efficient and step-economical access to sulfoxides from thiols and alkyl halides in the presence of I2O5 and DBU via direct oxidative coupling was described. It is the first case that combined Williamson sulfide synthesis and subsequent sulfide oxidation into one step manipulation for sulfoxides preparation This protocol features wide substrate scope, mild and metal-free conditons, the use of naturally abundant starting materials and avoidance of over-oxidation

Tetrahedron Letters published new progress about Aralkyl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Computed Properties of 611-19-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ghosh, Santanu; Jana, Chandan K. published the artcile< Metal-Free Thermal Activation of Molecular Oxygen Enabled Direct α-CH2-Oxygenation of Free Amines>, HPLC of Formula: 53581-86-5, the main research area is thermal activation mol oxygen; alpha methylene oxygenation amine; amide lactam preparation.

Direct oxidation of α-CH2 group of free amines is hard to achieve due to the higher reactivity of amine moiety. Therefore, oxidation of amines involves the use of sophisticated metallic reagents/catalyst in the presence or absence of hazardous oxidants under sensitive reaction conditions. A novel method for direct C-H oxygenation of aliphatic amines through a metal-free activation of mol. oxygen has been developed. Both activated and unactivated free amines were oxygenated efficiently to provide a wide variety of amides (primary, secondary) and lactams under operationally simple conditions without the aid of metallic reagents and toxic oxidants. The method has been applied to the synthesis of highly functionalized amide-containing medicinal drugs, such as O-Me-alibendol and -buclosamide.

Journal of Organic Chemistry published new progress about Aliphatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 53581-86-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO2, HPLC of Formula: 53581-86-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Shi, Guo Q.; Dropinski, James F.; Zhang, Yong; Santini, Conrad; Sahoo, Soumya P.; Berger, Joel P.; MacNaul, Karen L.; Zhou, Gaochao; Agrawal, Arun; Alvaro, Raul; Cai, Tian-Quan; Hernandez, Melba; Wright, Samuel D.; Moller, David E.; Heck, James V.; Meinke, Peter T. published the artcile< Novel 2,3-dihydrobenzofuran-2-carboxylic acids: Highly potent and subtype-selective PPARα agonists with potent hypolipidemic activity>, Reference of 35852-58-5, the main research area is hydroxydihydrobenzofurancarboxylate phenoxyalkyl iodide alkylation; phenoxyalkoxydihydrobenzofurancarboxylate preparation hydrolysis; phenoxylalkoxy dihydrobenzofurancarboxylic acid preparation PPAR ligand; dihydrobenzofurancarboxylic acid preparation phenoxylalkoxy asym preparation PPAR ligand.

The design and synthesis of a class of 2,3-dihydrobenzofuran-2-carboxylic acids, e.g., I, as highly potent and subtype-selective PPARα agonists are reported. Systematic study of structure-activity relationships has identified several key structural elements within this class for maintaining the potency and subtype selectivity. Select compounds were evaluated in animal models of dyslipidemia using Syrian hamsters and male Beagle dogs, and all these compounds displayed excellent cholesterol- and triglyceride-lowering activity at dose levels that were much lower than the marketed weak PPARα agonist fenofibrate.

Journal of Medicinal Chemistry published new progress about Alkylation. 35852-58-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H4ClF3O, Reference of 35852-58-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wang, Chunyu; Liu, Yingze; Shao, Yue; Tang, Zian; Wen, Zhendong; Liang, Fuxin; Yang, Zhenzhong published the artcile< Zwitterionic Polymer Hairy Coating onto Mesh toward Easy Oil/Water Separation>, COA of Formula: C9H9Cl, the main research area is zwitterionic sulfobetaine methacrylate polymer graft coating stainless steel mesh; oil water separation membrane coating stainless steel mesh; coating; hairy structures; meshes; oil/water separation; zwitterionic polymers.

A zwitterionic polymeric hair-coated stainless steel mesh membrane is fabricated, which demonstrates efficient separation of oil/H2O mixtures and emulsions. The hairy coating of poly(divinylbenzene-co-vinylbenzene chloride) is generated by precipitation cationic polymerization, and subsequently grafting a zwitterionic polymer layer by atom transfer radical polymerization of sulfobetaine methacrylate. The microstructure of the hairy coating is tunable from an array of individual nanofibers to porous networks by interweaving of the hairs. The long-range attraction of zwitterionic polymers with H2O renders the coated mesh with excellent superhydrophilic and underwater superoleophobic performance. The coated mesh is highly antifouling to avoid the prehydration in conventional methods. Also, the microstructure is responsible for the high separation efficiency of oil/H2O emulsion. Therefore, separation of oil/H2O mixtures and emulsions becomes easier by the coated mesh, which is promising in industrial oil field sewage treatment.

Macromolecular Rapid Communications published new progress about Atom transfer radical polymerization. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, COA of Formula: C9H9Cl.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Nakazato, Atsuro; Ohta, Kohmei; Sekiguchi, Yoshinori; Okuyama, Shigeru; Chaki, Shigeyuki; Kawashima, Yutaka; Hatayama, Katsuo published the artcile< Design, synthesis, structure-activity relationships, and biological characterization of novel arylalkoxyphenylalkylamine σ ligands as potential antipsychotic drugs>, Category: chlorides-buliding-blocks, the main research area is arylalkoxyphenylalkylamine preparation sigma ligand antipsychotic; structure activity arylalkoxyphenylalkylamine antipsychotic; sigma receptor antagonist arylalkoxyphenylalkylamine.

σ-Receptor antagonists may be effective antipsychotic drugs that do not induce motor side effects caused by ingestion of classical drugs such as haloperidol. The authors obtained evidence that 1-(2-dipropylaminoethyl)-4-methoxy-6H-dibenzo[b,d]pyran hydrochloride (I) had selective affinity for σ receptor over dopamine D2 receptor. This compound was designed to eliminate two bonds of apomorphine (II) to produce structural flexibility for the nitrogen atom and to bridge two benzene rings with a -CH2O- bond to maintain the planar structure. In light of the evidence, N,N-dipropyl-2-(4-methoxy-3-benzyloxyphenyl)ethylamine (III) was designed. Since compound III had eliminated a biphenyl bond of 6H-dibenzo[b,d]pyran derivative I, it might be more released from the rigid structure of apomorphine II than compound I. The chem. modification of compound III led to the discovery that N,N-dipropyl-2- [4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine hydrochloride (NE- 100), the best compound among arylalkoxyphenylalkylamine derivatives, had a high and selective affinity for σ receptor and had a potent activity in an animal model when the drug was given orally. The authors report here the design, synthesis, structure-activity relationships, and biol. characterization of novel arylalkoxyphenylalkylamine derivatives such as III.

Journal of Medicinal Chemistry published new progress about Antipsychotics. 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Koler, Amadeja; Krajnc, Peter published the artcile< Surface Modification of Hypercrosslinked Vinylbenzyl Chloride PolyHIPEs by Grafting via RAFT>, Application In Synthesis of 1592-20-7, the main research area is vinylbenzyl chloride hypercrosslinking surface modification polyHIPE grafting RAFT.

Grafting of glycidyl methacrylate from the surface of macroporous poly(4-vinylbenzyl chloride-co-divinylbenzene) polyHIPEs (poly high internal phase emulsions) prepared by the polymerization of the continuous phase of high internal phase emulsions is performed. PolyHIPEs are hypercrosslinked using Friedel-Crafts reaction thus increasing sp. surface area, and further functionalized with tris(2-aminoethyl) amine. To the free amino groups reversible addition-fragmentation chain transfer (RAFT) agent 4-cyano-4-[(dodecylsulfanylthiocarbonyl) sulfanyl] pentanoic acid is immobilized and grafting is performed utilizing glycidyl methacrylate. Poly(glycidyl methacrylate) chains of ≈100 units in length are grafted onto the surface of the polyHIPEs. In comparison, non-hypercrosslinked monoliths allow for substantially lower degree of immobilization of RAFT agent suggesting decreased accessibility of active sites on the polymer surface.

Macromolecular Chemistry and Physics published new progress about Crosslinking. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Application In Synthesis of 1592-20-7.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ahmadi-khaneghah, Aziz; Salehi, Saeed; Behniafar, Hossein published the artcile< Polystyrene networks with polyoxyethylene cross-links covalently grafted onto nano-SiO2 cores: surface-initiated ATRP and thermal investigations>, SDS of cas: 1592-20-7, the main research area is polystyrene network polyoxyethylene crosslink silica ATRP.

Crosslinked polystyrene loaded by silica nanoparticles (CPS/SNPs) with hydrophilic nature was prepared via a solvent-free surface-initiated atom transfer radical polymerization technique. Chem. immobilization of the initiator of the polyaddition reactions was performed on silica nanoparticles. Also, polyoxyethylene chains capped with styrenic end units were synthesized from the reaction of 4-chloromethyl styrene and polyethylene glycol with mole ratios of 2:1 and then used as the chain crosslinker. In addition to CPS/SNPs composite, a crosslinked material lacking silica cores (CPS) was also prepared by a similar technique. Thermal stabilities of the resulting crosslinked polystyrenes were fully investigated by thermogravimetric anal./differential thermogravimetry. The silica-containing crosslinked material clearly showed more thermal stability than the bare material. In addition, both CPS/SNPs and CPS presented thermal stabilities nearly as much as other polystyrene-silica materials reported in the literature. Thus, the polyoxyethylene crosslinks did not cause addnl. thermal sensitivity in the network obtained. Furthermore, DTA measurements demonstrated that the phase transition caused by the thermal decomposition in CPS/SNPs composite is significantly reduced due to the presence of silica cores.

Polymer Bulletin (Heidelberg, Germany) published new progress about Atom transfer radical polymerization. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, SDS of cas: 1592-20-7.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Hu, Cui-Xia; Chen, Lin; Hu, Di; Song, Xue; Chen, Zhi-Chao; Du, Wei; Chen, Ying-Chun published the artcile< Construction of Enantioenriched 9H-Fluorene Frameworks via a Cascade Reaction Involving Remote Vinylogous Dynamic Kinetic Resolution>, Electric Literature of 5153-70-8, the main research area is fluorene enantioselective preparation dicyanoolefin indanone cyclization dynamic kinetic resolution; dicyanoolefin indanone addition cascade cyclization dynamic kinetic resolution.

The benzylic C-H group of α,α-dicyanoolefins from 3-substituted 1-indanones could be significantly activated via transmission along the aromatic system, thus enabling dynamic kinetic resolution via a traditional reversible deprotonation-protonation process. Enantioenriched 9-substituted 9H-fluorene frameworks were finally constructed through an asym. vinylogous Michael addition to nitroolefins, followed by a cascade cyclization and oxidative aromatization process, under the catalysis of a chiral bifunctional thiourea-tertiary amine.

Organic Letters published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (cyano). 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Electric Literature of 5153-70-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Xiaojie; Jing, Xin; Zhao, Yong; Wang, Wei; Yu, Liangmin; Sun, Mingliang published the artcile< Small Organic Molecule Based Photoelectrodes for Efficient Photoelectrochemical Cathodic Protection>, Product Details of C8H3ClO3, the main research area is small organic mol photoelectrode efficient photoelectrochem cathodic protection.

Photoelectrochem. cathodic protection (PECCP) as a branch of photocatalysis and photoelectrochem. holds great promise for efficient anticorrosion. Organic semiconductors with tunable bandgaps and favorable optoelectronic properties were attracting more attention in the photoelectrochem. (PEC) field. However, its application for PECCP was marginally explored. Herein, the authors successfully fabricated a small organic mol. (ITIC: 3,9-bis(2-methylene-(3-(1,1- dicyanomethylene)-indanone))-5,5,11,11tetrakis(4hexylphenyl)-dithieno[2,3-d:2,3′-d’]-s-indaceno[1,2-b:5,6-b’]dithiophene) based photoelectrode for PECCP of 304 stainless steel (304SS). The PEC research proved that it could provide PECCP for 304SS with a photoinduced potential drop of 100 mV. A mol. structure design strategy was also adopted to broaden the light absorption spectrum of ITIC by halogenating the terminal group with the Cl atom. The obtained ITIC derivate (IT-2Cl)-based photoelectrode provided a higher photoinduced potential drop of 150 mV for PECCP of 304SS. More impressively, the separation of photoinduced electron-hole pairs was promoted and the electron transportation was accelerated, when introducing TiOx thin film as the electron acceptor and electron transportation channel in the photoelectrode. Consequently, the PECCP for 304SS was dramatically enhanced, with the potential drop increasing to 290 mV. The flexible mol. design strategy and improved PECCP performance proposed a guideline for the potential applications of organic semiconductor-based photoelectrodes in the PECCP field.

ACS Applied Electronic Materials published new progress about Cathodic protection. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Product Details of C8H3ClO3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics