Author: Jessica.F

Strzelczyk, Marek published the artcileSynthesis of perhydro-1,2,5-dithiazepine derivatives of potential pharmacological activity, Application In Synthesis of 1002-41-1, the publication is Polish Journal of Pharmacology and Pharmacy (1984), 36(5), 473-84, database is CAplus and MEDLINE.

Perhydro-1,2,5-dithiazepines, e.g., I [R = H (II), Ph₂CH (III)] were prepared via cyclocondensation of ClCH₂CH₂SSCH₂CH₂Cl with amines. II and III showed spasmolytic, antihistaminic, and anticholinergic activities stronger than their analogs containing a perhydro-1,4-thiazepine system, but weaker than diphenhydramine.

Polish Journal of Pharmacology and Pharmacy published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C15H14O3, Application In Synthesis of 1002-41-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Strzelczyk, Marek published the artcileSynthesis of 7-9-membered heterocyclic systems containing nitrogen and sulfur with expected pharmacological activity. I. Synthesis of perhydro-1,4,5-thiadiazocine, -1,4,6-thiadiazonine, and -1,2,5,7-dithiadiazonine derivatives, Name: 1,2-Bis(2-chloroethyl)disulfane, the publication is Acta Poloniae Pharmaceutica (1985), 42(4), 337-44, database is CAplus.

RCONHNHCOR (R = Me, Et, Ph, 2,4-Cl₂C₆H₃) were converted with NaNH₂ in C₆H₆ into the di-Na salts, which, condensed with Cl(CH₂)₂S(CH₂)₃Cl (I) in DMF, yielded 4,5-diacylperhydro-1,4,5-thiadiazocines II. 4,5-Bis(phenylsulfonyl)perhydro-1,4,5-thiadiazocine was prepared analogously from PhSO₂NHNHSO₂Ph. An analogous reaction with (MeNH)₂CO (III) gave thiadiazonine IV (X = CH₂), which was also obtained directly from I and III, refluxed in hexanol containing some Na₂CO₃. The latter method was also used to obtain the dimer IV (X = S) from III and (ClCH₂CH₂S)₂ (V), whereas meso-2,3-diaminobutane-2HCl, condensed under similar conditions with V, yielded VI.

Acta Poloniae Pharmaceutica published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C8H11NO, Name: 1,2-Bis(2-chloroethyl)disulfane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sorokin, Helen P. published the artcileLiving cells of pea seedlings. I. Survey of vacuolar precipitates, mitochondria, and spherosomes, Product Details of C22H23ClN4, the publication is American Journal of Botany (1956), 787-94, database is CAplus.

cf. C.A. 50, 9533b. The topmost portion of the 3rd internode in etiolated 7-day-old pea stems contained a definitely outlined region where Janus Green B (I) was reduced to diethylsafranin. Some cells in this region, particularly those adjacent to the starch sheath, formed stable, copious, brilliant blue-green precipitates of A-type vacuoles. Combined staining with I and neutral red separated red precipitates from blue mitochondria. The latter were recognized by the reversible coloration and decolorization of I under aerobic and anaerobic conditions, resp. They became dark red when incubated with neotetrazolium chloride.

American Journal of Botany published new progress about 4569-86-2. 4569-86-2 belongs to chlorides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride, and the molecular formula is C3H8N2S, Product Details of C22H23ClN4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Singh, Man published the artcileEffect of trimethylsulphoxonium halide surfactants on consolute solutions of immiscible solvents, COA of Formula: C3H9ClOS, the publication is Physics and Chemistry of Liquids (2011), 49(3), 302-308, database is CAplus.

Consolute solution temperatures (CST) ± 0.01 K and corresponding solubilities of phenol-water mixtures with 0.35 millimol kg-1 trimethylsulfoxonium chloride (TMSOC), trimethylsulfoxonium bromide (TMSOB), and trimethylsulfoxonium iodide (TMSOI) cationic surfactants are reported. The halide surfactants (TMSOX, X = Cl-, Br-, I-) decreased the CST by about 1.73-2.18° with 3-5% less mutual mixing as compared to phenol-water mixtures Three -CH3 (methyl) and the chloride (Cl-), bromide (Br-) and iodide (I-) halide ions of surfactants had developed hydrophobic and hydrophilic interactions, resp. The CST data are as TMSOI > TMSOB > TMSOC with corresponding mutual solubilities as TMSOC > TMSOB > TMSOI, with slightly stronger I–water interaction due to induced potential of a large-sized iodide ion. The hydrophobic interactions mildly dominated with smaller sized Cl- anion with slightly higher mutual solubility Comparatively, consolute solutions with surfactants are obtained at slightly lower temperatures with higher mutual mixing.

Physics and Chemistry of Liquids published new progress about 5034-06-0. 5034-06-0 belongs to chlorides-buliding-blocks, auxiliary class Salt,Aliphatic hydrocarbon chain, name is trimethyloxosulphonium chloride, and the molecular formula is 0, COA of Formula: C3H9ClOS.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shapiro, David published the artcileSome derivatives of amidone, Application of 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, the publication is Journal of Organic Chemistry (1949), 839-48, database is CAplus.

Because amidone (I) possesses biol. properties some ring-substituted I, its fluorene analog, 9-(2-dimethylaminopropyl)-9-propionylfluorene (II), and 4,5-diphenyl-4-(2-dimethylaminopropyl)-3-pentanone (III), have been synthesized. To crude PhCHBrCN (prepared by addition of 17 cc. Br to 35 g. PhCH₂CN at 105-10° within 0.5 hr.) in 150 cc. C₆H₆ is added within 20-30 min. 42 g. powd. AlCl₃ at 45-50°, the mixture heated 1 hr. at 60-5°, the C₆H₆ distilled off (up to 125° bath temperature), the residue decomposed with 800 cc. ice H₂O containing 20 cc. concentrated HCl, the mixture steam-distilled 20 min., and the reddish oil distilled, giving 74% Ph₂CHCN, b_0.2 121-5°, m. 75°. Ph(p-MeC₆H₄)CHCN (IV), prepared in a similar way in 65% yield, b₄ 164-70°, m. 61°; Ph(p-MeOC₆H₄CHCN (V) (32%), b₂ 155-65°; Ph(p-BrC₆H₄)CHCN (VI) (80%), b_0.8 172-6°, m. 82-3°; Ph(PhCH₂)CHCN (VII), b_0.6 158-70°, m. 58°, is prepared in 32% yield by adding 38 g. PhCH₂Cl to 40 g. PhCH₂CN in 150 cc. BuOH containing 7 g. dissolved Na, and refluxing the mixture 4 hrs. Me₂NH (65 g.), 65 g. MeCH(OH)CH₂Cl, and 90 g. PhMe, mixed at 5°, are heated 10 hrs. in an autoclave at 95-100°, the mixture filtered, the residue washed with 250 cc. PhMe, the combined PhMe solution added at 10-15° to 165 g. SOCl₂ in 400 cc. PhMe, and the mixture heated 6 hrs. at 100°, giving 83% MeCHClCH₂NMe₂.HCl, from which the free base (VIII) is liberated with K₂CO₃. Treating 4.4 g. NaNH₂ suspended in 75 cc. PhMe containing 12 g. VIII with 19 g. 9-cyanofluorene in 180 cc. PhMe at 45-50°, heating the mixture 1 hr. at 55-60°, refluxing 1.25 hrs., extracting with 15% HCl, and making the washed aqueous solution alk. give 76% of a mixture (IX), viscous pale yellow oil, b_0.3 168-70°, of RCH₂MeNMe₂ and RCHMeCH₂NMe₂ (R = 9-cyano-9-fluorenyl), also obtained when MeCH(NMe₂)CH₂Cl (X) is used in lieu of VIII (cf. Schultz and Sprague, C.A. 42, 4934i). V and VIII (or X), treated in the same way, give 44% of a mixture b_0.1 162-8°, of Ph(p-R’C₆H₄)C(CN)CH₂CHMeNMe₂ (XI) and Ph(p-R’C₆H₄ C(CN)CHMeCH₂NMe₂ (XII) (R’ = MeO). IV and VIII (or X) give 69% of a mixture, b_0.1 148-55°, of XI and XII (R’ = Me); VI and VIII (or X) give 74% of a mixture, b_0.05 162-70°, of XI and XII (R’ = Br); VII and VIII (or X) give a mixture (XIII), b_0.1 148-55°, of Ph(PhCH₂)C(CN) CH₂CHMeNMe₂ and Ph(PhCH₂)C(CN) CHMeCH₂NMe₂. The nitriles are treated directly with EtMgBr and the resulting ketimines hydrolyzed. IX (20 g.) in 100 cc. C₆H₆ is added to EtMgBr from 6.5 g. Mg and 26 cc. EtBr in 60 cc. boiling ether, the ether being simultaneously distilled off, the mixture refluxed 10 hrs., decomposed with ice-cold NH₄Cl, extracted with cold 25% H₂SO₄, the sq. solution washed with C₆H₆, 50 cc. H₂SO₄ added, and the mixture heated 1.5 hrs. at 100° and made alk., giving 65% II, b_0.6 152-8°, m. 66-8° (HCl salt, m. 262-4°). In the same way mixtures of R”CH₂CHMeNMe₂ (XIV) and R”CHMeCH₂NMe₂ (XV) [R” = Ph(p-R’C₆H₄)(EtCO)C] are prepared (R’, yield, b.p., m.p. of HCl salt (a) and picrate (b) in the order given); Me, 82%, b₂ 175-80°, a 202-4°, b 138-40°; MeO, 60%, b_0.1 160-3°, a 162-3°, b 178-9°; Br, 80%, b_0.1 175-80°, a 205-7°, b 153-4°. Treatment of XIII in the same way gives 75% of a mixture, b_0.2 174-8°, of XIV and XV [R” = Ph(PhCH₂)(EtCO)C][HCl salt, crystallizing with H₂O, m. 100-3°, (H₂O-free) m. 145-7°; picrate m. 164-6°, from which III [XIV, R” = Ph(PhCH₂)(EtCO)C], m. 67-8°, is obtained with NaOH]. MeCH:CHCOPh (42 g.) and 30 g. NHMe₂ in 60 g. PhMe mixed at 5-10°, then heated 18 hrs. at 60°, the solvent evaporated in vacuo, and the residue heated 2 hrs. at 70°, give 45 g. β-(dimethylamino)butyrophenone (XVI), decompose on purification (picrate, m. 122-3°). XVI with EtMgBr gives 1,1-diphenyl-3-dimethylamino-1-butanol (XVII), m. 120-2° (picrate m. 160-2°). XVII is not reduced in HClO₄ in the presence of Raney Ni or Pd. Heating XVII with KHSO₄ 1.5 hrs. at 150-60° gives 1,1-diphenyl-3-dimethylamino-1-butene, oil (picrate, m. 195-6°), which is hydrogenated in 6 hrs. with Ni at 20° and atm. pressure to the butane analog (picrate, m. 138-40°). XVI and PhCH₂MgBr give 28% 4,5-diphenyl-2-dimethylamino-4-pentanol (XVIII), m. 94-5° (picrate, m. 135-7°). Dehydration of XVIII with KHSO₄ and hydrogenation of the pentene give 4,5-diphenyl-2-(dimethylamino)pentane [picrate (XIX), m. 168-70°]. Heating 1 g. III with 0.8 g. NaOH and 5 cc. triethyleneglycol 4 hrs. at 220-5°, extracting the mixture with ether, and treating the ether extract with picric acid give XIX. The ultraviolet absorption curves of the ketones are given. II in doses of 0.5-5 mg./kg. shows a slight analgetic action; with 10 mg./kg. tono-clonic convulsions are observed in rabbits. The lethal dose is 62 mg./kg. II has also a spasmolytic effect of about the same order as papaverine-HCl.

Journal of Organic Chemistry published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C4H6N2, Application of 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanli, Nazmiye Ozlem published the artcileEffects of material type on biofilm response to an oxidising biocide in a laboratory-scale cooling tower system: Effect of material type in response to biocide, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Johnson Matthey Technology Review (2021), 65(2), 161-169, database is CAplus.

Biofilms in industrial cooling tower systems are an important problem. The importance of the surface material in the response to an oxidising biocide (chloramine T trihydrate) was substantiated in our study. Polyvinyl chloride (PVC) cooling tower fill material, stainless steel cooling tower construction material and glass surfaces were compared by evaluating the bacterial loads on materials before and after biocidal treatment. The greatest logarithmic decrease in bacterial load was recorded as >3 log for glass after the first two months and for PVC after the second month. Actively respiring bacterial counts and ATP (ATP) measurements showed that there was no significant difference in the sensitivity of biofilmassocd. cells to the biocide on the different surfaces. In addition, the effect of the biocidal treatment decreased with increasing biofilm age, regardless of the material.

Johnson Matthey Technology Review published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanli, Nazmiye Ozlem published the artcileEvaluation of biocidal efficacy of Chloramine T trihydrate on planktonic and sessile bacteria in a model cooling tower water system, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Water Science and Technology (2019), 79(3), 526-536, database is CAplus and MEDLINE.

In the current study, model cooling tower system was exptl. seeded with Legionella pneumophila and real industrial cooling tower (CT) water has been run at the closest to full-scale system operating conditions. The water/biofilm samples were taken from the model system monthly, and the effectiveness of the different concentrations of Chloramine T trihydrate biocide was evaluated in terms of its ability to control both planktonic/sessile microbial populations. Although Chloramine T is a recommended com. formulation for disinfecting CTs, there is a lack of published data on the efficacy of this compound against both planktonic and sessile populations in the cooling tower. Biocide response in both sessile/planktonic bacteria counts varied according to months. Tested biocide concentrations provided the clean tower conditions by reducing the concentration of heterotrophic plate count (HPC) below <104 cfu mL-1, L. pneumophila <10 cfu mL-1 and of ATP (ATP) values <300 relative light units (RLU), after 1, 3 and 24 h of exposure, during a 6-mo period. There were no statistically significant differences in efficacy between concentrations in terms of reduction in the number of bacteria, decrease in ATP value and viability. The results revealed that Chloramine T can effectively control biofouling in cooling systems according to the limit values of the successful control program.

Water Science and Technology published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ruefenacht, Kurt published the artcilePhosphoric acid esters and thiophosphoric acid esters with some heterocyclic substitutions. 7. Thio- and dithiophosphoric acid esters of the GS 13005 type with some analog or homolog heterocyclic rings, Product Details of C3H3Br2ClO, the publication is Helvetica Chimica Acta (1973), 56(7), 2186-204, database is CAplus.

Analogs of the pesticide GS 13005 were prepared, including pyrazolinones of the type I, (R = Cl, OH), pyrazoles II, (R = H, Me, Cl; R1 = H, Cl, Br, NO2; R2 = H, Me, iso-Pr; R3 = Cl, OH), pyridazinones III, (R = H, Cl, Br, Me, Et; R1 = H, Cl, Me; R2 = H, Cl, Me; R3 = Cl, OH), thiadiazinones IV, (R = Me, Et; R1 = Cl, OH), and their mono- and dithiophosphates. The preparation, of analogous thiadiazepinones failed, giving instead pyrazolidinone derivatives Approx. 100 compounds were prepared

Helvetica Chimica Acta published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Product Details of C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Rebrova, R. N. published the artcileComparative study of the effect of decamine and decamethoxine on fungi of the genus Candida, diphtheria bacteria and pathogenic staphylococci, Formula: C38H74Cl2N2O4, the publication is Vestnik Dermatologii i Venerologii (1971), 45(11), 51-2, database is CAplus and MEDLINE.

Decamine [522-51-0] had a stronger fungistatic effect against Candida albicans than did decamethoxine (I) [38146-42-8], but I was more effective than decamine in preventing the growth of diphtheria bacteria and pathogenic staphylococci. I may be useful in treating diseases caused or complicated by diphtheria or staphylococci organisms.

Vestnik Dermatologii i Venerologii published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Formula: C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Pernot, Robert published the artcileThe reaction of ethylene with sulfur monochloride (S₂Cl₂) and with sulfur dichloride (S₂Cl₂ + Cl₂) in the preparation of bis(2-chloroethyl) sulfide (mustard gas), Safety of 1,2-Bis(2-chloroethyl)disulfane, the publication is Ann. chim. [12] (1946), 626-57, database is CAplus.

Crude mustard gas (I) as obtained in the Levinstein process is a clear yellow liquid, m. 10.5°, which does not deposit a trace of S when kept for over a year. On distillation in vacuo I gives 70% pure (ClCH₂CH₂)₂S.(II), m. 13.5°. I is only partially soluble in EtOH or ether. The m.p. is only slightly affected when byproducts are present. When 500 g. I is extracted with 500 cc. EtOH, 208 g. remains undissolved. On cooling the alc. solution, 130 g. II, m. 13.3°, crystallizes. When 500 g. I is cooled with ice-NaCl, 245 g. II, m. 12.5°, crystallizes. Distillation of 323 g. I gives 2 fractions, (a) 185 g., b₁₈ 110-15°, m. 13.3°, and (b) 40 g., b₁₈ 115-55°, m. 3.8°, the residue decomposing Redistillation of 40 g. of fraction a gives a fraction (c) 25 g., b₁₈ 110-15°, and 12 g., b₁₈ 120-35°, the latter being chiefly (ClCH₂CH₂)₂S₂ (III). Distillation of the EtOH solution gives II, but no III or (ClCH₂CH₂)₂S₃ (IV) is present. From the EtOH-insoluble part no definite product can be isolated even on distillation at 1 mm. It still contains a small amount of II which is removed by careful oxidation with H₂O₂, whereby II is oxidized to the H₂O-soluble sulfoxide while III and IV remain unchanged. The elementary composition of the residue after treatment with H₂O₂ corresponds to (ClCH₂CH₂)₂S₈ (V) which may be formed according to the following equation: 7S₂Cl₂ + 14C₂H₄ → 6 II + V. Treatment of 86 g. EtOH-insoluble product with moist NH₃ according to Felsing and Arenson (C.A. 15, 54) causes the separation of 16.5 g. S. The recovered product, now soluble in ether and C₆H₆, is free of N and has a composition corresponding to (ClCH₂CH₂)₂S₄ (VI). VI does not deposit S even after standing 6 mo. When VI is heated with S, the latter dissolves and seps. again on cooling. In an attempt to hydrolyze VI with alc. KOH no definite compound is formed. When VI is treated with Me₂CO, S is deposited with the formation of IV, m. 27°. IV is also formed when VI is treated with steam at 100 mm. An attempt to oxidize IV with BzO₂H, to transfer it into the iodine compound by heating it with NaI in a sealed tube, or to condense IV with PhONa or BzONa failed. Distillation of 50 g. IV at 1 mm. gives 40 g. yellow liquid, b₁ 120-35°. Redistillation of the latter gives 2 fractions, (d) 10 g., b₁ up to 120°, and (e) 28 g., b₁ 120-6°, containing chiefly IV, m. 26.5°. IV prepared according to Mann, et al. (C.A. 15, 2413), m. 25°; the mixed m.p. of the 2 preparations is 26°. When IV is heated with the theor. amount of S to form VI, the S dissolves but seps. again on cooling. IV when distilled at 40 mm. gives a small amount of III, b. 160-5°, which is not attacked by H₂O₂. When distilled at atm. pressure III gives a very small amount of II. These results show that III has the structure (ClCH₂CH₂S)₂ and not (ClCH₂CH₂)₂S:S, while IV has the structure ClCH₂CH₂S(:S)SCH₂CH₂Cl. When 220 g. EtOH-insoluble product is extracted 5 times with 200 cc. pure and dry Me₂CO and the Me₂CO is evaporated, 80 g. of yellow oil is obtained from which some (ClCH₂CH₂)₂SO crystallizes. The residual oil has a composition corresponding to (ClCH₂CH₂)₂S₅ (VII) and is insoluble in EtOH, petr. ether, and AcOH. Pyridine precipitates 8.5 g. S from 43 g. VII. Evaporation of the pyridine leaves an oil which on distillation at 3 mm. gives a mixture of III and IV. The Me₂CO-insoluble part (140 g.), when cooled, deposits 16 g. S. The filtrate consists of a polysulfide or a mixture of polysulfides high in S content (75.7-6.7%). The hypothesis that II is formed according to the equation S₂Cl₂ + 2C₂H₄ → II + S is not substantiated by the action of C₂H₄ upon S₅Cl₂. When 580 g. S₅Cl₂ is treated with C₂H₄, 733 g. reaction product is obtained from which 207 g. S deposits, giving 526 g. reaction product. From 342 g. S₂Cl₂, which equals 580 g. S₅Cl₂, and 142 g. C₂H₄, 484 g. reaction product is calculated while 526 g. is obtained. These results indicate that S₅Cl₂ reacts in the same way as S₂Cl₂. The following reaction mechanism is proposed: S₂Cl₂ + 3C₂H₄ gives a sesquimustard gas, (CH₂SCH₂CH₂Cl)₂ (VIII). VIII reacts with S₂Cl₂ to give 1 mol. II and ClSS₂CH₂CH₂Cl (IX); IX + C₂H₄ → IV. IV + S₂Cl₂ → Cl.S.CH₂CH₂Cl (X) + ClS₄CH₂CH₂Cl (XI); XI + C₂H₄ → II + VI, etc. SCl₂ + C₂H₄ gives 85% crude reaction product (XII), m. 5-8°. Distillation of 109.5 g. XII, m. 5.5°, gives 3 fractions: (f) 97.5 g., b₁₀ 93-6°, m. 10°; (g) 4.5 g., b₁₀ 96-105°; and 3.5 g. residue. Redistillation of 90 g. f gives a fraction, 76.5 g., b₁₂ 97-8°, m. 10°, which on redistillation gives 62.3 g., b₁₃ 101-2°, m. 10.2°, and 11.4 g., b₁₅ 102-4°, m. 11.8°. This indicates that with II other products come over. Because under the conditions used, SCl₂ can be considered to be a solution of Cl in a mixture of SCl₂ and S₂Cl₂, byproducts containing α-chlorinated compounds are formed which split off HCl with formation of ClCH:CHSCH₂CH₂Cl (XIII). II containing 8.8% XIII m. 9.9°. When SCl₂ in a 10% CCl₄ solution and C₂H₄ are allowed to react and the reaction product is distilled after the CCl₄ has been removed at 120°, II, b₁₀ 93.5-4°, m. 10.8°, is obtained. When 800 g. of the reaction product is extracted with EtOH only 31 g. insoluble product (XIV) is obtained. When Cl is passed into 250 g. XIV, the temperature rises to 45-50°. As soon as the temperature drops to room temperature the Cl current is stopped and the reaction product distilled in vacuo. Up to 70°/15 mm. the S-Cl compounds distill, and between 98° and 100° a few cc. of a turbid liquid distills. When C₂H₄ is passed at 30-40° into the residue, a vigorous reaction takes place. After the active Cl in the residue has disappeared, 303 g. of a clear red solution is obtained. Distillation of 238 g. of this solution gives 3 fractions: (h) 12.6 g., b₁₃ 40-97°; (i) 76.6 g., b₁₃ 97-107°; (j) 8.2 g., b₁₃ 107-25°. Redistillation of i gives a product, b₁₃ 98-101°, m. 8.6°. Oxidation of 4.3 g. of this product with H₂O₂ at 50° in AcOH gives 1.2 g. of a sulfoxide, m. 108°, which when mixed with the sulfoxide of II, m. 108°. These results indicate that the Cl splits the polysulfides, ClCH₂CH₂S(:S_x)S(:S_y)CH₂CH₂Cl, to give 2 mols. X, while the S is converted into SCl₂ which again reacts with C₂H₄ with excess formation of a certain amount of II. On the other hand, the Cl also reacts with X, giving rise to the formation of XIV.

Ann. chim. [12] published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Safety of 1,2-Bis(2-chloroethyl)disulfane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics