Month: December 2022

Li, Bin published the artcileGold(I)-Coordination Triggered Multistep and Multiple Photochromic Reactions in Multi-Dithienylethene (DTE) Systems, Computed Properties of 219537-97-0, the publication is Inorganic Chemistry (2012), 51(3), 1933-1942, database is CAplus and MEDLINE.

The preparation, characterization, and photochromic properties of a mononuclear Au(I) complex (100) with two identical DTE-acetylides and a dinuclear Au(I) complex (2000) with both DTE-acetylide and DTE-diphosphine are described. Both Au(I) complexes exhibit multistep and multiple photocyclization/cycloreversion reactions. Particularly, four-state and four-color photochromic switch is successfully achieved for the dinuclear Au(I) complex upon irradiation with appropriate wavelengths of light. In contrast, fully ring-closed form is unattained through multiple photocyclization for the two corresponding model organic compounds coupling with the same DTE units as Au(I) complexes but without Au(I)-participation. It is demonstrated that coordination of Au(I) ion to DTE-acetylides exerts indeed a crucial role in achieving stepwise and selective photocyclization and cycloreversion reactions for both Au(I) complexes, in which the coordinated Au(I) atom acts as an effective “barrier” to prohibit intramol. energy transfer between multi-DTE moieties.

Inorganic Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Computed Properties of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Guan-Wu published the artcileMechanochemical aminochlorination of electron-deficient olefins with chloramine-T promoted by (diacetoxyiodo)benzene, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Advanced Synthesis & Catalysis (2007), 349(11+12), 1977-1982, database is CAplus.

A direct and convenient procedure for the solvent-free mechanochem. aminochlorination of electron-deficient olefins promoted by (diacetoxyiodo)benzene [PhI(OAc)₂] was described using com. available and cheap chloramine-T as a nitrogen and chlorine source. The vicinal chloramine derivatives were obtained in high regio- and stereoselectivity with good yields. PhI(OAc)₂ was superior to metal salts for the aminochlorination of electron-deficient olefins.

Advanced Synthesis & Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C10H10O2, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yang, Shan published the artcileRegioselective Sulfonylvinylation of the Unactivated C(sp³)-H Bond via a C-Centered Radical-Mediated Hydrogen Atom Transfer (HAT) Process, HPLC of Formula: 21286-54-4, the publication is Organic Letters (2019), 21(12), 4837-4841, database is CAplus and MEDLINE.

Given the similarity of multiple sp³ C-H bonds in electronic properties and bond dissociation energy (BDE), regioselective sp³ C-H bond functionalization remains a paramount challenge. Here, the authors report a C-centered radical-mediated approach for site-specific sulfonylvinylation of the C(sp³)-H bond via the hydrogen atom transfer (HAT) process. The reaction features mild conditions, broad substrate scope, and high regioselectivity and stereoselectivity, manifesting the nontrivial synthetic potential.

Organic Letters published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C9H9NO6S, HPLC of Formula: 21286-54-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Lei, Ying-jie published the artcileUltrasound assisted synthesis and antibacterial activity of 4-(coumarin-3-yl)-2-arylaminothiazoles, Category: chlorides-buliding-blocks, the publication is Huaxue Shiji (2018), 40(6), 518-522, 588, database is CAplus.

In this work, 3-(2-bromoacetyl)-2H-chromen-2-ones prepared from 3-acetyl coumarins with tetrabutylammonium tribromide on bromination were used as the raw material. An efficient approach toward the synthesis of 4-(coumarin-3-yl)-2-arylaminothiazoles was carried out by the reaction of the starting compounds with certain Ph thioureas in presence of PEG-400 under ultrasound irradiation at a frequency of 40 kHz in 20âˆ?0 min, with a yield of 81.6%âˆ?3.0%. The structures of target compounds were confirmed by IR, ¹HNMR, ¹³CNMR, MS and elemental anal. Preliminary bioassay results showed that some of them have certain antibacterial activities against Staphylococcus aureus, Bacillus subtilis and Escherichia coli. This method is operationally simple and environmentally benign and the solvent could be reused for several times.

Huaxue Shiji published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yuan, Yang published the artcilePalladium-Catalyzed Carbonylative Synthesis of N-Heterocycles from 1-Chloro-2-fluorobenzenes, Formula: C7H6ClF, the publication is European Journal of Organic Chemistry (2019), 2019(11), 2172-2175, database is CAplus.

A simple and efficient synthesis of pyrido-fused quinazolinones and dibenzoxazepinones by palladium-catalyzed annulation of com. available substituted 1-chloro-2-fluorobenzenes and 2-aminopyridines or 2-aminophenols was developed. The reaction involved carbonylation/aromatic nucleophilic substitution sequential in a one-pot manner.

European Journal of Organic Chemistry published new progress about 116850-28-3. 116850-28-3 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzene, name is 2-Chloro-1-fluoro-3-methylbenzene, and the molecular formula is C24H29N5O3, Formula: C7H6ClF.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yu, Yi published the artcileElectrochemical Sulfoxidation of Thiols and Alkyl Halides, Quality Control of 939-99-1, the publication is Journal of Organic Chemistry (2022), 87(10), 6942-6950, database is CAplus and MEDLINE.

A green and efficient electrochem. sulfoxidation via the use of readily available materials, i.e., thiols and alkyl halides was reported. The simple operation, mild conditions and broad substrate scope render this protocol potentially applicable for the preparation of diverse synthetically significant sulfoxides RSOCH₂R¹ [R = i-Pr, 4-FC₆H₄, 4-ClC₆H₄, etc.; R¹ = (CH₂)₂CH₃, Ph, 3-MeOC₆H₄, etc.].

Journal of Organic Chemistry published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C21H24O8, Quality Control of 939-99-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Lai, J. S. published the artcilePreparation of sulfur ylide complexes of platinum by phase transfer catalysis, Application of trimethyloxosulphonium chloride, the publication is Journal of Organometallic Chemistry (1990), 393(3), 431-40, database is CAplus.

Various sulfur ylide complexes of Pt were prepared by the phase transfer catalysis (PTC). Thus, reaction of Pt(PR₃)₂Cl₂ (R = Me, Ph) in CH₂Cl₂ with [S(O)(CH₃)₃]I under PTC/OH^– conditions give complexes {Pt(PR₃)₂[(CH₂)₂S(O)(CH₃)]}I, which contain a bidentate double sulfur ylide. With Pt(dppe)Cl₂ [dppe = Ph₂P(CH₂)₂PPh₂] as starting material, a similar product was obtained. But when Pt(dppm)Cl₂ [dppm = Ph₂PCH₂PPh₂] was treated with [S(O)(CH₃)₃]Cl under PTC/OH^– conditions, an unexpected product {Pt(PPh₂CH₃)(PPh₂OH)[(CH₂)₂S(O)(CH₃)]}Cl was obtained. This compound contains a bidentate double sulfur ylide and two unsym. phosphines resulting from the base hydrolysis of dppm. Compound {Pt(PPh₃)₂[(CH₂)₂S(O)(CH₃)]}I, was subjected to an x-ray diffraction study.

Journal of Organometallic Chemistry published new progress about 5034-06-0. 5034-06-0 belongs to chlorides-buliding-blocks, auxiliary class Salt,Aliphatic hydrocarbon chain, name is trimethyloxosulphonium chloride, and the molecular formula is C3H9ClOS, Application of trimethyloxosulphonium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chen, Cheng published the artcileDiscovery of cytochrome bc₁ complex inhibitors inspired by the natural product karrikinolide, Safety of 2-Chloro-4-methylphenylboronic acid, the publication is RSC Advances (2016), 6(100), 97580-97586, database is CAplus.

The cytochrome bc₁ complex (cyt bc₁ or complex III) is a promising target of numerous antibiotics and fungicides. With an aim to indentify new lead structures for the bc₁ complex, a series of novel inhibitors were discovered from the natural product karrikinolide for the first time. Extensive screening results suggested variable inhibitory activities of these compounds against succinate-cytochrome reductase [SCR, a mixture of respiratory complex II (SQR) and complex III (the bc₁ complex)], implying the essential role of a 4-substituted Ph group for the high potency. Exceptionally, compound 12g showed excellent inhibition potency having an IC₅₀ value in the sub-micromolar range, demonstrating its higher potency than the com. control amisulbrom by over two orders of magnitude. Further experiments inferred that these newly prepared compounds mainly target the bc₁ complex. Seemingly, this work has presented a new lead scaffold for further development of bc₁ complex inhibitors.

RSC Advances published new progress about 145349-62-8. 145349-62-8 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids, name is 2-Chloro-4-methylphenylboronic acid, and the molecular formula is C7H8BClO2, Safety of 2-Chloro-4-methylphenylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fu, Ying published the artcileDebenzylative Sulfonylation of Tertiary Benzylamines Promoted by Visible Light, Safety of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, the publication is European Journal of Organic Chemistry (2021), 2021(12), 1896-1900, database is CAplus.

An efficient, general, inexpensive, and environmentally friendly photosynthesis of sulfonamides via visible light promoted debenzylative sulfonylation of tertiary benzylamines is described. Compared to the traditional S-N coupling reactions, which are promoted by oxidative C-N bond cleavage of sym. tertiary alkylamines, this strategy provides a selective C-N bond cleavage protocol and avoids the use of transition-metal, explosive oxidants, and ligands.

European Journal of Organic Chemistry published new progress about 32333-53-2. 32333-53-2 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Sulfonyl chlorides,Benzene, name is 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, and the molecular formula is C7H3Cl2F3O2S, Safety of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wu, Hsyueh-Liang published the artcileEnantioselective addition of organozinc reagents to carbonyl compounds catalyzed by a camphor derived chiral γ-amino thiol ligand, Category: chlorides-buliding-blocks, the publication is Tetrahedron (2016), 72(21), 2656-2665, database is CAplus.

The design and synthesis of the chiral camphor derived γ-amino thiol ligand I and its application in catalytic enantioselective carbon-carbon forming reactions through the addition of organozinc reagents (R)₂Zn (R = Me, Et) to carbonyl compounds R¹CHO (R¹ = 2-ClC₆H₄, 2-thienyl, cyclohexyl, etc.) have been described. The catalytic activity and enantioselectivity of ligand I were demonstrated in the enantioselective addition of various organozinc reagents to aldehydes and ketoesters ArC(O)CO₂CH₃ (Ar = 2-H₃CC₆H₄, 2-furyl, 2-naphthyl, etc.), offering the corresponding alcs. e.g., 4-BrC₆H₄CH(OH)CH₃ in high yields and enantioselectivities. The role of the mercapto group in the highly enantioselective 1,2-addition reaction of organozincs to aldehyde was also discussed.

Tetrahedron published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C7H11N, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics