Month: December 2022

Zhang, Xiulian published the artcileAryldiazonium ion initiated C-N bond cleavage for the versatile, efficient and regioselective ring opening of aziridines, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Organic Chemistry Frontiers (2019), 6(11), 1832-1836, database is CAplus.

Aryldiazonium salts were proved to initiate the regioselective cleavage of aziridines for the installation of varied functional groups to gave β-substituted aryl sulfonamides I [R¹ = Ph, 4-MeC₆H₄, 4-ClC₆H₄, etc.; R² = H, Me; R³ = OMe, OBn, SPh, etc.]. The ring-opening process was effective and general for a variety of nucleophiles, including [O], [S] and [N] at room temperature This highly regioselective process, which could be performed at the gram scale, enjoys operational simplicity, as well as mild and metal-free conditions. The postulated reaction mechanism involved a single electron transfer from aziridines to aryldiazonium salts, which generates a highly reactive amino radical cation.

Organic Chemistry Frontiers published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C8H10S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fox, Richard J. published the artcileGeneral User Guide for Partitioning of Tetraalkylammonium and Tetraalkylphosphonium Salts: Impacts of Cation, Anion, and Solvent, Category: chlorides-buliding-blocks, the publication is Organic Process Research & Development (2020), 24(2), 235-241, database is CAplus.

Using a gravimetric approach, the partitioning of 57 tetraalkylammonium and 10 tetraalkylphosphonium salts in 12 different organic solvent/water mixtures was determined The data show that the partitioning is dramatically affected by the identity of the cation, anion, and solvent, and this comprehensive compilation can serve as a general user guide to aid as a starting point for reagent selection, especially in cases where efficient removal of the tetraalkylammonium or phosphonium salt is required.

Organic Process Research & Development published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhang, Shuai-Bing published the artcileAntifungal mechanism of 1-nonanol against Aspergillus flavus growth revealed by metabolomic analyses, Product Details of C7H16ClNO2, the publication is Applied Microbiology and Biotechnology (2021), 105(20), 7871-7888, database is CAplus and MEDLINE.

Chem. control of fungal spoilage of postharvest cereal grains is an important strategy for the management of grain storage. Here, the potential antifungal activity of 1-nonanol, a main component of cereal volatiles, against Aspergillus flavus was studied. The growth of A. flavus was completely inhibited by 0.11 and 0.20 μL/mL 1-nonanol at vapor and liquid contact phases, resp. Metabolomic anal. identified 135 metabolites whose expression was significantly different between 1-nonanol-treated and untreated A. flavus. These metabolites were involved in the tricarboxylic acid cycle, amino acid biosynthesis, protein degradation and absorption, aminoacyl-tRNA biosynthesis, mineral absorption, and in interactions with ABC transporters. Biochem. validation confirmed the disruptive effect of 1-nonanol on A. flavus growth, as indicated by the leakage of intracellular electrolytes, decreased succinate dehydrogenase, mitochondrial dehydrogenase, and ATPase activity, and the accumulation of reactive oxygen species. We speculated that 1-nonanol could disrupt cell membrane integrity and mitochondrial function and might induce apoptosis of A. flavus mycelia. Simulated grain storage experiments showed that 1-nonanol vapor, at a concentration of 264 μL/L, completely inhibited A. flavus growth in wheat, corn, and paddy grain with an 18% moisture content. This study provides new insights into the antifungal mechanism of 1-nonanol against A. flavus, indicating that it has a promising potential as a bio-preservative to prevent fungal spoilage of postharvest grains. 1-Nonanol showed higher antifungal activity against A. flavus. · The antifungal mechanisms of 1-nonanol against A. flavus were revealed. · 1-Nonanol could damage cell membrane integrity and mitochondrial function.

Applied Microbiology and Biotechnology published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C2H2N4O2, Product Details of C7H16ClNO2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yan, Qing published the artcileAll-visible-light triggered solid-state dual-color fluorescence switching of phenanthroimidazole-based bisthienylethene, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2022), 10(18), 7024-7030, database is CAplus.

All-visible-light controlled fluorescence switching is more promising for bioimaging. Constructing dual-color fluorescent bisthienylethene (BTE) systems are quite challenging. Here, all-visible-light triggered dual-color fluorescence switching was achieved in a color-specific switching manner in a solid-state by associating the photochromic BTE core with a blue emissive phenanthroimidazole (PI) unit. Unique emission behavior caused by J-aggregation of the coplanar PI unit was crucial, which suggested a novel strategy for constructing dual-color fluorescent photoswitching. Moreover, a ‘turn-off’ fluorescence photoswitching was demonstrated in solution and PMMA films owing to the energy transfer from the PI moiety to a ring-closed isomer of the BTE moiety. Remarkably, an all-visible-light patterning application for information storage medium was developed with these compounds BTE-P1 was successfully utilized in cellular imaging for efficient fluorescence switching.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C18H34N4O5S, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zheng, Kewang published the artcileAdsorption of Cu²⁺ by modified chitosan microspheres and its application in homocoupling of arylboronic acid, Synthetic Route of 145349-62-8, the publication is Arabian Journal of Chemistry (2022), 15(10), 104170, database is CAplus.

The modified chitosan microspheres were first prepared by emulsification and investigated the performance of the chitosan adsorbent for the adsorption of copper ions. The catalytic performance of chitosan-supported copper microspheres in the self-coupling of arylboronic acids using 4-methoxybenzene as the model substrate was evaluated, while exploring a wide range of substrates including aryl boronic acid derivatives and heterocyclic arylboronic acids, including aldehyde, nitro, and aldehyde groups. The exptl. results show that good to excellent yields (55%-95%) of the desired dimer products were obtained under mild conditions at room temperature and in air, and the catalytic material could be reused up to five times with no significant decrease in catalytic activity.

Arabian Journal of Chemistry published new progress about 145349-62-8. 145349-62-8 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronic Acids, name is 2-Chloro-4-methylphenylboronic acid, and the molecular formula is C15H24S, Synthetic Route of 145349-62-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Cai, Xing-wei published the artcileLead/rare earth-free green-light-emitting crystal of molecular-based hybrid compound: (C₅H₁₃ClN)₂[MnCl₄] with large crystal size, COA of Formula: C5H13Cl2N, the publication is Wuji Huaxue Xuebao (2018), 34(2), 283-288, database is CAplus.

Reaction of MnCl₂ and 2-dimethylaminoisopropyl chloride hydrochloride afforded one novel mol.-based material, (C₅H₁₃ClN)₂[MnCl₄] (1). And it is interesting to note that 1 exhibits intense greenish fluorescent emission (520 nm) at room temperature and relatively high thermal stability (stable up to 450 K). Moreover, structure and spectra analyses reveal that its excellent optical property can be attributed to the ⁴T₁ (G) → ⁶A₁ electronic transition of Mn²⁺ in [MnX₄]^2- tetrahedron.

Wuji Huaxue Xuebao published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C5H13Cl2N, COA of Formula: C5H13Cl2N.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Wei published the artcilePalladium-Catalyzed Thiocarbonylation of Benzyl Chlorides with Sulfonyl Chlorides for the Synthesis of Arylacetyl Thioesters, Computed Properties of 939-99-1, the publication is Advanced Synthesis & Catalysis (2021), 363(10), 2541-2545, database is CAplus.

A convenient procedure for the synthesis of thioesters RCH₂C(O)SR¹ (R = Ph, 3,4-dimethylphenyl, naphthalen-1-yl, thiophen-3-yl, etc.; R¹ = Ph, 2,4,6-trimethylphenyl, naphthalen-1-yl, etc.) has been developed via a palladium-catalyzed thiocarbonylation of benzyl chlorides RCH₂Cl with sulfonyl chlorides R¹S(O)₂Cl. Various arylacetyl thioesters were produced in good yields by using sulfonyl chlorides as an odorless sulfur source. Furthermore, W(CO)₆ exhibited dual roles as both a solid CO surrogate and reductant here.

Advanced Synthesis & Catalysis published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C7H8BClO2, Computed Properties of 939-99-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Wei published the artcilePalladium-Catalyzed Thiocarbonylation of Benzyl Chlorides with Sulfonyl Chlorides for the Synthesis of Arylacetyl Thioesters, Product Details of C7H6Cl2, the publication is Advanced Synthesis & Catalysis (2021), 363(10), 2541-2545, database is CAplus.

A convenient procedure for the synthesis of thioesters RCH₂C(O)SR¹ (R = Ph, 3,4-dimethylphenyl, naphthalen-1-yl, thiophen-3-yl, etc.; R¹ = Ph, 2,4,6-trimethylphenyl, naphthalen-1-yl, etc.) has been developed via a palladium-catalyzed thiocarbonylation of benzyl chlorides RCH₂Cl with sulfonyl chlorides R¹S(O)₂Cl. Various arylacetyl thioesters were produced in good yields by using sulfonyl chlorides as an odorless sulfur source. Furthermore, W(CO)₆ exhibited dual roles as both a solid CO surrogate and reductant here.

Advanced Synthesis & Catalysis published new progress about 620-20-2. 620-20-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 3-Chlorobenzylchloride, and the molecular formula is C12H10FeO4, Product Details of C7H6Cl2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Sheng published the artcilePhotoswitching of bisthienylethene using 2D-π-A type pyran-based fluorescent dye for rewritable optical storage, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Dyes and Pigments (2011), 89(2), 188-192, database is CAplus.

The photoswitching of photochromic bisthienylethene mixed electron donor-π-accepter (2D-π-A) type fluorescent dye with appropriate doping ratio was constructed, which showed excellent fluorescence switch “on” and “off” when the photochromic bisthienylethene undergoes ring-opening and ring-closed photoisomerization with UV and visible-light irradiation in solution and PMMA film. The erasable and rewritable photoimages on the photochromic bisthienylethene mixed 2D-π-A type fluorescent dye in PMMA were successfully demonstrated, which will provide a simple and viable method for optical data storage based photochromic fluorescent materials. These developments are crucial for fundamental research and eventual tech. application for all-photo mode high-d. optical data storage.

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C13H18N2, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zamani, Farzad published the artcileOxazolidinones and 2,5-Dihydrofurans via Zinc-Catalyzed Regioselective Allenylation Reactions of L-α-Amino Aldehydes, Computed Properties of 21286-54-4, the publication is Journal of Organic Chemistry (2017), 82(13), 6819-6830, database is CAplus and MEDLINE.

The simultaneous control of diastereoselectivity and regioselectivity in Zn-catalyzed allenylation reactions of N-protected L-α-amino aldehydes is reported. A reversal in diastereoselectivity could be realized by variation of the α-amino aldehyde protecting groups. A range of 1-allenyl-2-amino alcs. were obtained with excellent regioselectivity and converted to oxazolidinones and dihydrofurans. Many oxazolidinones and dihydrofuran could be isolated as single diastereoisomers and without significant erosion of ee, making this a practical catalytic synthesis of highly functionalized heterocycles.

Journal of Organic Chemistry published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C4H7BrO2, Computed Properties of 21286-54-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics