Tag: M.W=300-350

Feng, Yanli published the artcilePhotochromic thiophene oligomers based on bisthienylethene: syntheses, photochromic and two-photon properties, Application of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of Materials Chemistry (2006), 16(37), 3685-3692, database is CAplus.

A series of novel, functional sym. and unsym. photochromic thiophene oligomers based on bisthienylethenes (BTEs) were synthesized via control of the reaction condition with a Suzuki coupling method. Their optical, photochromic quantum yields, two-photon and electrochem. properties in THF as well as in poly(Me methacrylate) (PMMA) films were measured and discussed. The fluorescence emission can be tuned reversibly by alternating irradiation with UV and visible light. These BTEs could be used as nanowires, fluorescent switch and electrochem. switch.

Journal of Materials Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Application of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Yannian published the artcilePhotodynamic Chiral Molecular Switches with Thermal Stability: From Reflection Wavelength Tuning to Handedness Inversion of Self-Organized Helical Superstructures, Related Products of chlorides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2013), 52(51), 13703-13707, database is CAplus and MEDLINE.

We previously developed a dithienylcyclopentene dopant that bears two methylenedioxy-bridged binaphthyl moieties. Herein, we report our new findings on related compounds that entail different bridge lengths in their binaphthyl units. Three new compounds were synthesized. It was found that variations of the bridge length resulted in significantly different photoresponsive properties in LC media.

Angewandte Chemie, International Edition published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhou, Zhiguo published the artcileModulation of the Photochromic Property in an Organoboron-Based Diarylethene by a Fluoride Ion, Category: chlorides-buliding-blocks, the publication is Organic Letters (2006), 8(18), 3911-3914, database is CAplus and MEDLINE.

Organoboron-based diarylethene was successfully synthesized and exhibited photochromic property. Furthermore, its photochromic property can be modulated by a fluoride ion. The absorption maximum of the photostationary state shifted from 655 to 490 nm upon addition of a fluoride ion. The modulation mechanism is attributed to the special Lewis acid-base interaction between a trivalent boron atom and a fluoride ion.

Organic Letters published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H15OP, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Chenguang published the artcileAutomated synthesis of prexasertib and derivatives enabled by continuous-flow solid-phase synthesis, Recommanded Product: 2-Chlorotrityl chloride, the publication is Nature Chemistry (2021), 13(5), 451-457, database is CAplus and MEDLINE.

Recent advances in end-to-end continuous-flow synthesis are rapidly expanding the capabilities of automated customized syntheses of small-mol. pharmacophores, resulting in considerable industrial and societal impacts; however, many hurdles persist that limit the number of sequential steps that can be achieved in such systems, including solvent and reagent incompatibility between individual steps, cumulated byproduct formation, risk of clogging and mismatch of timescales between steps in a processing chain. To address these limitations, herein a strategy that merges solid-phase synthesis and continuous-flow operation, enabling push-button automated multistep syntheses of active pharmaceutical ingredients, is reported. The application of this methodol. is demonstrated with a six-step synthesis of prexasertib in 65% isolated yield after 32 h of continuous execution. As there are no interactions between individual synthetic steps in the sequence, the established chem. recipe file was directly adopted or slightly modified for the synthesis of twenty-three prexasertib derivatives, enabling both automated early and late-stage diversification.

Nature Chemistry published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Recommanded Product: 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Feng, Ke published the artcileModular Design of Poly(norbornenes) for Organelle-Specific Imaging in Tumor Cells, COA of Formula: C19H14Cl2, the publication is Biomacromolecules (2016), 17(2), 538-545, database is CAplus and MEDLINE.

Through modular ROMP (ring-opening metathesis polymerization) directly from monomeric norbornenes of bioactive peptides, rhodamine B chromophore, and PEG solubilizer, we designed and synthesized a series of water-soluble poly(norbornenes) with organelle-specific imaging capability in tumor cells. For the selection of F_xrF_xK, TAT, and SV40 peptide sequences, these fluorescence probes exhibited different targeting specificity toward mitochondria, lysosome, and nucleolus, resp., based on the same poly(norbornene) backbonds. More importantly, the ROMP strategy enables selective combination from various monomers and allows programmable biofunctionalization via peptide sequence permutations, which would greatly extend the biomedical applications such as imaging, diagnosis, and therapy for these synthetic polymers.

Biomacromolecules published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, COA of Formula: C19H14Cl2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Wenjie published the artcileTriptycene-based porous polymers regulated by diarylethenes, Related Products of chlorides-buliding-blocks, the publication is Dyes and Pigments (2018), 72-76, database is CAplus.

Linear and star triptycene-based porous polymers regulated by diarylethenes were constructed via Pd (0)-catalyzed Suzuki coupling reaction, resp. Both triptycene-based porous polymers performed reversible photochromism in solid state but exhibited distinctive solvent-dependent photochromism in solution Their surface area and porous properties were further analyzed by nitrogen sorption isotherms. Results showed that the sp. surface areas and total pore volumes of the two polymers can be reversibly tuned by adjusting the open- and the closed-ring of diarylethene upon irradiating with UV and visible light. These distinctive properties have potential applications in the photo-switched gas adsorption and the probe of chloride solvents.

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yan, Liying published the artcileFluorescent molecular photoswitch based on basket-shaped porphyrins, SDS of cas: 219537-97-0, the publication is Tetrahedron Letters (2020), 61(29), 152104, database is CAplus.

Here we present two novel basket-shaped porphyrins bridged by photochromic diarylethene derivatives, which show significant photoswitchable fluorescent properties. Their synthesis, structures, photochromism and fluorescence characteristics were reported in detail. They are desirable for reversible light-driven fluorescent mol. switches.

Tetrahedron Letters published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C7H9BN2O3, SDS of cas: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhang, Jing published the artcileMultifunctional Mesoporous Silica Nanoparticles Based on Charge-Reversal Plug-Gate Nanovalves and Acid-Decomposable ZnO Quantum Dots for Intracellular Drug Delivery, Application of 2-Chlorotrityl chloride, the publication is ACS Applied Materials & Interfaces (2015), 7(48), 26666-26673, database is CAplus and MEDLINE.

A novel type of pH-responsive multifunctional mesoporous silica nanoparticle (MSN) was developed for cancerous cells drug delivery and synergistic therapy of tumor. MSNs were covered with a kind of cell-penetrating peptide, deca-lysine sequence (K₁₀), to enhance their escape from the endosomes. After K₁₀‘s primary amines were reacted with citraconic anhydride to form acid-labile β-carboxylic amides, zinc oxide (ZnO) quantum dots (QDs) were introduced to cap MSNs via electrostatic interaction. The obtained ZnO@MSN drug-delivery system (DDS) achieves “zero-premature” drug release under a physiol. environment. However, once the DDS is transferred to the cancerous cells’ acidic endosome, ZnO QDs would rapidly dissolve and the acid-labile amides on the side chain of K₁₀ would hydrolyze to regenerate primary amines, resulting in the uncapping of MSNs and exposure of the cell-penetrating peptide K₁₀. The regenerated K₁₀ could help the DDS escape from the endosome and efficiently release the loaded drugs inside the cells. At the meantime, because of the cytotoxicity of ZnO QDs at their destination, the ZnO@MSN DDS may achieve a synergistic antitumor effect to improve the therapeutic index.

ACS Applied Materials & Interfaces published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C4H6O3, Application of 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Singh, Ravinder published the artcileMonomeric and aggregation emissions of tetraphenylethene in a photo-switchable polymer controlled by cyclization of diarylethene and solvent conditions, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2017), 5(38), 9952-9962, database is CAplus.

A novel photo-switchable polymer P-PHT containing diarylethene (DAE) and tetraphenylethene (TPE) moieties and a triazole linker in the repeating unit was synthesized to study the aggregation-induced emission (AIE) behavior of TPE with both the open and closed forms of DAE in P-PHT with high water contents. The photo-switching phenomena of DAE (from open to closed forms under UV-irradiation) in P-PHT were prominent in organic solvent (THF), high water contents (at 90% H₂O) and acidic conditions. Upon UV-irradiation of P-PHT at 90% water content, the AIE of TPE was completely quenched via an energy transfer event from TPE to cyclized DAE. Interestingly, the rare monomeric emission of TPE was first discovered by the photo-cyclization of DAE in P-PHT compared with the AIE behavior of TPE with the open form of DAE in P-PHT with AIE favorable conditions of high water content (90% H₂O) and acidic conditions.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C16H18Br2ClN3O3, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Jiang, Lianzhong published the artcileA photochromic dye doped polymeric Mach-Zehnder interferometer for UV light detection, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of Materials Chemistry C: Materials for Optical and Electronic Devices (2019), 7(21), 6257-6265, database is CAplus.

Owing to the compact size, immunity to electromagnetic interference, high sensitivity and real-time monitoring, optical waveguide sensors based on a refractive index change have become an emerging approach for smart sensing in the internet-of-things system. For this purpose, the synergetic efforts in material engineering (sensing materials) and optical engineering (waveguide design and fabrication) are both indispensable. Here we report a Mach-Zehnder interferometer (MZI) waveguide with photochromic dye-doped polymer sensing films for UV light detection. Firstly, UV light induced photochromism of a synthesized dye DAECHO in solution and in the solid state is investigated to understand the relationship between their structure and optical properties, especially the photochromism-induced refractive index change for waveguide sensors. Then the MZI structure is designed and simulated to optimize the performance of refractive index sensing. Following the standard microfabrication process of double photolithog.-development, the device is fabricated with a DAECHO doped polymer as a sensing cladding material for UV light detection. The evanescent sensing of MZI is performed to detect weak UV light from 10 μW cm^-2 to 100 μW cm^-2 at 365 nm. Our demonstration of MZI for UV light detection indicates the potential of portable and highly sensitive UV light waveguide sensors for real-life applications.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics