Tag: M.W=150-200

Ge, Qianqian; Liang, Xian; Ding, Liang; Hou, Jianqiu; Miao, Jibin; Wu, Bin; Yang, Zhengjin; Xu, Tongwen published the artcile< Guiding the self-assembly of hyperbranched anion exchange membranes utilized in alkaline fuel cells>, Safety of 1-(Chloromethyl)-4-vinylbenzene, the main research area is hyperbranched polyvinylbenzyl chloride diamine crosslinked anion exchange membrane; self assembly hyperbranched anion exchange membrane alk fuel cells.

Anion exchange membrane fuel cells (AEMFCs) can efficiently convert chem. energy into electricity at high pH. However, as the critical component, the existing anion exchange membranes (AEMs), cannot have both high stability and high conductivity, which is intrinsic to the conventional linear AEMs. To address this, here we report hyperbranched AEMs cross-linked by diamines and proposed a strategy to guide the self-assembly of hyperbranched AEMs, thereby regulating the membrane microphase morphol. We found that the chain length of the diamine crosslinking agents plays a significant role in guiding the formation of microphase separated morphol. inside hyperbranched AEMs and influences eventually the membrane conductivity and stability. The hyperbranched membrane HBM-6C exhibits the most distinct microphase separated morphol., leading to high conductivity and improved alk. stability. For instance, the hydroxide conductivity of HBM-6C membrane is 27.18 mS cm-1 at 30 °C, 2.7 times of the linear counterpart membrane [PTMVPMA][OH] (10 mS cm-1). A H2/O2 AEMFC assembled with HBM-6C membrane herein demonstrates a maximum power d. of 97 mW cm-2 at a c.d. of 190 mA cm-2. Our results would pave the way towards AEMs with novel chain architecture and stimulate further improvement in AEMFC performance.

Journal of Membrane Science published new progress about Alkaline fuel cells. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Safety of 1-(Chloromethyl)-4-vinylbenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Shi, Xiu-dong; Ge, Bing-chen; Xu, Jiang-ping; Zhou, Zhong-zhen published the artcile< Synthesis, crystal structure and antitumor activity of 6-chloro-1-((6-chloropyridin-3-yl)methyl)-3-phenyl-1H-benzofuro[3,2-c]pyrazole>, Computed Properties of 22717-55-1, the main research area is benzofuropyrazole preparation crystal structure antitumor activity.

The title compound 6-chloro-1-((6-chloropyridin-3-yl)methyl)-3-phenyl-1H-benzofuro[3,2-c]pyrazole (I, C21H13Cl2N3O, Mr = 394.26) was synthesized and characterized by elemental anal., 1H NMR, 13C NMR and X-ray single-crystal diffraction. The structure reveals that the crystal belongs to the triclinic system, space group P1 with a = 7.8829(8), b = 10.3281(10), c = 11.7615(12)Å, α = 83.5552(2), β = 79.921(2), γ = 70.189(2) degree, V = 885.54(15)Å3, Z = 2, Dc = 1.479 g/cm3, μ = 0.383 mm-1, F(000) = 404, R = 0.0538 and wR = 0.1335 for 2453 observed reflections with I>2σ(I). The result revealed that the crystal structure of the title compound I was stabilized by three C-Cl···π interactions and π···πstacking interaction. In addition, the preliminary investigation showed that I exhibited remarkably good antitumor activity against the MCF-7 and A549 cell lines.

Chinese Journal of Structural Chemistry published new progress about Antitumor agents. 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Computed Properties of 22717-55-1.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chien, Chih-Wei; Liu, Kwang-Ting; Lai, Chung K. published the artcile< Substituent effects in columnar β-diketonate metallomesogens>, Computed Properties of 3964-57-6, the main research area is diketonate copper palladium complex homologous series columnar mesophase preparation; crystal structure copper palladium diketonate complex; substituent effect copper palladium diketonate complex mesophase; liquid crystal copper palladium diketonate columnar mesophase preparation; metallomesogen diketonate columnar mesophase preparation.

A systematic study of the mesomorphic properties of two homologous series of copper(II) and palladium(II) complexes (1a-b) derived from unsym. β-diketonate derivatives (I) containing a variety of functional substituents (X = H, CH3, C2H5, OCH3, Cl, Br, I, CN) on the Ph ring is reported. These disk-like mols. all contain eight n-octyloxy chains, required for the formation of columnar phases appended to the central β-diketonate core. All complexes exhibited columnar phases studied by DSC, polarized optical microscopy and powder x-ray diffraction. The mesomorphic results indicated that all compounds formed stable enantiotropic columnar mesophases, and the formation of columnar phases was strongly dependent on the electronic and/or the steric factors of the substituents. For compounds containing bulky substituents (i.e. X = Me, Et) a rectangular columnar phase (Colr) was observed, however, other compounds containing electron-withdrawing substituents (i.e. X = Cl, Br, I) exhibited a hexagonal columnar phase (Colh). Most of the palladium(II) complexes, except for X = CH3 and OCH3 derivatives, have lower clearing temperatures than those of the copper(II) analogs, and this is probably due to a weaker mol. interaction between the cores in the palladium(II) complexes. Lattice constants for these two types of compound obtained by powder x-ray diffraction are insensitive to the metal center incorporated. These values were all relatively close in magnitude, which indicated that the two structures were quite similar. A satisfactory linear relation with a correlation coefficient of 0.974 between the clearing temperatures and the Hammett σp constants of substituents was obtained only for the copper complexes.

Journal of Materials Chemistry published new progress about Crystal structure. 3964-57-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Computed Properties of 3964-57-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wang, Wenyuan; Chen, Hongjin; Yue, Youfeng; Zhang, Rui; Liu, Jian published the artcile< Electropolymerization of V-shape D-A-D type monomers for efficient and tunable electrochromics>, Recommanded Product: 4,5-Dimethoxybenzene-1,2-diamine, the main research area is electrochromic triphenylamine quinoxaline derivative preparation electrochem polymerization.

Five novel donor-acceptor-donor (D-A-D) type monomers (VQ1 ∼ VQ5) with a common V-shape configuration have been developed and further electropolymerized for electrochromic applications. The monomers were designed by introducing two triphenylamine groups into the 2- and 3- position of the quinoxaline derivates, resp. These redox-active monomers could be electrodeposited robustly on the ITO electrodes in an electrolyte solution via the oxidative coupling reactions between triphenylamine radical cations. The obtained thin polymer films (PVQ1 ∼ PVQ5) exhibited reversible redox behaviors and obvious color changes upon voltage variation. All these polymers exhibited excellent electrochromic performances involving high optical contrast (over 70%), short response time (less than 2 s) and high coloration efficiency (over 200 cm2 C-1). Moreover, the optical properties of these polymers in both neutral state and oxidation state can be tuned by variation of the addnl. substituents on the quinoxaline parts, resp.

Dyes and Pigments published new progress about Absorption spectra. 27841-33-4 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H12N2O2, Recommanded Product: 4,5-Dimethoxybenzene-1,2-diamine.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Pingping; Liu, Xu; Wang, Shi; Zeng, Qinghui; Wang, Zhinan; Li, Zengxi; Zhang, Liaoyun published the artcile< Confining Hyperbranched Star Poly(ethylene oxide)-Based Polymer into a 3D Interpenetrating Network for a High-Performance All-Solid-State Polymer Electrolyte>, Name: 1-(Chloromethyl)-4-vinylbenzene, the main research area is hyperbranched star PEO interpenetrating network solid polymer battery electrolyte; solid lithium battery electrolyte PEO polystyrene nanoconfinement crosslinking; 3D rigid framework; all-solid-state polymer electrolyte; hyperbranched star polymer; lithium-ion battery; nanoconfinement.

The original poly(ethylene oxide)-based polymer electrolytes normally show low ionic conductivity and inferior mech. property, which greatly restrict their practical application in all-solid-state lithium-ion batteries (LIBs). In this work, a hyperbranched star polymer with poly(ethylene glycol) Me ether methacrylate flexible chain segments is embedded into a three-dimensional (3D) interpenetrating crosslinking network created by the rapid one-step UV-derived photopolymerization of the cross-linker (ethoxylated trimethylolpropane triacrylate) in the presence of lithium salt. The rigid 3D network framework provides the polymer electrolyte with not only enhanced mech. behavior, including film-forming and dendrite-inhibiting capabilities, but also nanoconfinement effects, which can speed up polymer chain segmental dynamics and reduce the crystallinity of the polymer. Depending on this unique rigid-flexible coupling network, the prepared solid polymer electrolyte shows enhanced ionic conductivity (6.8 × 10-5 S cm-1 at 50 °C), widened electrochem. stability window (5.1 V vs Li/Li+), and enough mech. stability to suppress the growth of uneven Li dendrite (the Li sym. cells can operate steadily at both current densities of 0.05 and 0.1 mA cm-2 for 1000 h). Moreover, the assembled LiFePO4//Li cell also exhibited good cycle performance at 50 °C, making the hyperbranched star polymer electrolyte with a nanoconfined crosslinking structure to have potential application in high-safety and high-performance LIBs.

ACS Applied Materials & Interfaces published new progress about Activation energy. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Name: 1-(Chloromethyl)-4-vinylbenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Koo, Hyungmo; Kim, Hun Young; Oh, Kyungsoo published the artcile< (E)-Selective Friedel-Crafts acylation of alkynes to β-chlorovinyl ketones: Defying isomerizations in batch reactions by flow chemistry approaches>, Related Products of 17082-09-6, the main research area is beta chlorovinyl ketone diastereoselective preparation; alkyne acyl chloride Friedel Crafts acylation trichloroaluminum promoted flow.

The Friedel-Crafts acylation of alkynes stereoselectively provides (Z)-β-chlorovinyl ketones, whereas the AlCl3-promoted reaction yields a mixture of stereoisomeric β-chlorovinyl ketones. To develop the (E)-selective synthesis of β-chlorovinyl ketones (E)-RC(Cl):C(R2)COR1 [R = n-pentyl, c-hexyl, (CH2)2Ph, etc., R1 = cyclopropyl, Ph, 2-thienyl, etc., R2 = H, n-propyl], a flow chem. approach was devised for the Friedel-Crafts acylation of alkynes with acyl chlorides that defied the facile (E) → (Z) isomerization under AlCl3-promoted reaction conditions. Compared to batch reactions, the flow chem. approach provided a fast, clean, high yielding and stereoselective synthetic route to (E)-β-chlorovinyl ketones.

Organic Chemistry Frontiers published new progress about Acid halides Role: RCT (Reactant), RACT (Reactant or Reagent). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Related Products of 17082-09-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhou, Yu; Yang, Cheng-Li; Ye, Lei; Dong, Zhi-Bing published the artcile< Copper-Catalyzed C-S Formation for the Synthesis of Benzyl Phenyl Sulfides from Dithiocarbamates>, Recommanded Product: 1-Chloro-2-(chloromethyl)benzene, the main research area is benzyl phenyl sulfide green preparation; phenyl dithiocarbamate benzyl halide coupling copper catalyst.

An odorless and efficient protocol for the synthesis of benzyl Ph sulfides RSCH2R1 [R = Ph, 2-MeC6H4, 4-ClC6H4, etc.; R1 = Ph, 4-MeOC6H4, 2-BrC6H4, etc.] was reported. Starting from environmentally friendly Ph dithiocarbamates and com. available benzyl halides as starting materials, the target compounds (benzyl Ph sulfides) could be obtained smoothly and easily by using copper salt as catalyst and Cs2CO3as base. This method featured ligand/additive-free, the use of readily available starting materials, inexpensive catalysts, and good substrate suitability, illustrating its potentially synthetic value for the convenient preparation of some biol. active mols.

Synthesis published new progress about Benzyl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Recommanded Product: 1-Chloro-2-(chloromethyl)benzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Takebuchi, Haruka; Kubosawa, Hiroki; Jin, Ren-Hua published the artcile< Synthesis and Thermo-responsiveness of Double Hydrophilic Block Copolymers with PNIPAM Coils and Poly(methyloxazoline)/Poly(ethyleneimine) Combs>, Recommanded Product: 1-(Chloromethyl)-4-vinylbenzene, the main research area is isopropylacrylamide methyloxazoline ethyleneimine comb coil block copolymer hydrophilicity thermoresponsivity.

Two types of double-hydrophilic comb-coil block copolymers, (PVBC-g-PMOZ)-b-PNIPAM and (PVBC-g-PEI)-b-PNIPAM, possessing combs of poly(methyloxazoline) (PMOZ)/crystalline poly(ethyleneimine) (PEI) and coils of thermo-responsive poly(N-isopropylacrylamide) (PNIPAM) were synthesized by a combination of RAFT block copolymerization of 4-chloromethyl styrene and N-isopropylacrylamide (NIPAM), ring-opening polymerization of 2-methyloxazoline, and the selective hydrolysis of PMOZ. These polymers showed remarkable thermo-responsiveness to give thermo-induced aggregates with different morphologies.

Chemistry Letters published new progress about Cationic ring-opening polymerization. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Recommanded Product: 1-(Chloromethyl)-4-vinylbenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Song, Ming-Yu; Cao, Chen-Yu; He, Qiu-Rui; Dong, Qing-Miao; Li, Ding; Tang, Jiang-Jiang; Gao, Jin-Ming published the artcile< Constructing novel dihydrofuran and dihydroisoxazole analogues of isocombretastatin-4 as tubulin polymerization inhibitors through [3+2] reactions>, Application In Synthesis of 53581-86-5, the main research area is dihydrofuran dihydroisoxazole isocombretastatin analog preparation tubulin polymerization inhibitor; Combretastatin-4; Dihydrofuran; Dihydroisoxazole; Isocombretastatin-4; Tubulin polymerization inhibitors; [3+2] reactions.

[3+2] Reactions play a key role in constructing various pharmaceutical moleculars. In this study, using Mn(OAc)3 mediated and 1,3-dipolar [3+2] cyclization reactions, 38 novel dihydrofuran and dihydroisoxazole analogs of isoCA-4 were synthesized as inhibitors of tubulin polymerization Among them, compound 6g (5-(3-(4-chlorophenyl)-5-(3,4,5-trimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)-2-methoxyphenol) was found to be the most potent cytotoxic agents against PC-3 cells with IC50 value of 0.47 μM, and compound 5p ((5-(3-hydroxy-4-methoxyphenyl)-2-phenyl-5-(3,4,5-trimethoxyphenyl)-4,5-dihydrofuran-3-yl)(phenyl)methanone) exhibted highest activity on HeLa cells with IC50 vaule of 2.32 μM. Tubulin polymerization assay revealed that 6g was a dose-dependent and effective inhibitor of tubulin assembly. Immunohistochem. studies and cell cycle distribution anal. indicated that 6g severely disrupted microtubule network and significantly arrested most cells in the G2/M phase of the cell cycle in PC-3 cells. In addition, mol. docking studies showed that two chiral isomers of 6g can bind efficiently and similarly at colchicine binding site of tubulin.

Bioorganic & Medicinal Chemistry published new progress about Antitumor agents. 53581-86-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO2, Application In Synthesis of 53581-86-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics