Tag: M.W=150-200

Shee, Sujan; Panja, Dibyajyoti; Kundu, Sabuj published the artcile< Nickel-Catalyzed Direct Synthesis of Quinoxalines from 2-Nitroanilines and Vicinal Diols: Identifying Nature of the Active Catalyst>, Computed Properties of 27841-33-4, the main research area is nitroaniline benzenediamine vicinal diol nickel dehydrogenative coupling cyclocondensation catalyst; quinoxaline preparation.

The inexpensive and simple NiBr2/1,10-phenanthroline system-catalyzed synthesis of a series of quinoxalines from both 2-nitroanilines and 1,2-diamines is demonstrated. The reusability test for this system was performed up to the seventh cycle, which afforded good yields of the desired product without losing its reactivity significantly. Notably, during the catalytic reaction, the formation of the heterogeneous Ni-particle was observed, which was characterized by PXRD, XPS, and TEM techniques.

Journal of Organic Chemistry published new progress about Anilines Role: RCT (Reactant), RACT (Reactant or Reagent) (nitro). 27841-33-4 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H12N2O2, Computed Properties of 27841-33-4.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Koini, Eftychia N.; Alvonitis, Nicolaos; Calogeropoulou, Theodora published the artcile< Simple and efficient method for the halogenation of oxygenated aromatic compounds>, Application of C8H7ClO3, the main research area is oxygenated benzene acetic acid hydrogen peroxide hydrohalic chlorination bromination; arylchloride arylbromide preparation.

An efficient and mild method for the chlorination and bromination of oxygenated aromatics, with good regioselectivity and excellent yields, using a combination of HX/H2O2/AcOH in petroleum ether is presented. The effect of ultrasound was investigated.

Synlett published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent) (oxygenated). 3964-57-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Application of C8H7ClO3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wu, Mingxi; Wang, Mingjin; Cao, Song published the artcile< Copper(I)-catalyzed trifluoromethylation of phthalic anhydride derivatives with (trifluoromethyl)trimethylsilane>, Electric Literature of 118-45-6, the main research area is phthalic anhydride fluoromethylsilane trifluoromethylation copper catalyst; naphthalic anhydride fluoromethylsilane trifluoromethylation copper catalyst; fluoromethylhydroxyisobenzofuran lactone preparation; fluoromethylhydroxynaphthopyranone lactone preparation.

An efficient copper-catalyzed trifluoromethylation of substituted phthalic anhydrides using (trifluoromethyl)trimethylsilane (Me3SiCF3) as a nucleophilic trifluoromethylating reagent in the presence of 1,10-phenanthroline and KF, followed by quenching the reaction mixture with water was developed. A possible mechanism was suggested.

Chinese Journal of Chemistry published new progress about Anhydrides, cyclic Role: RCT (Reactant), RACT (Reactant or Reagent). 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Electric Literature of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kajigaeshi, Shoji; Shinmasu, Yoichi; Fujisaki, Shizuo; Kakinami, Takaaki published the artcile< Halogenation using quaternary ammonium polyhalides. XXVI [1]. Chlorination of phenols with benzyltrimethylammonium tetrachloroiodate>, COA of Formula: C8H7ClO3, the main research area is chlorination phenol benzyltrimethylammonium tetrachloroiodate.

The reaction of phenols with [PhCH2NMe3]+ [ICl4]- in CH2Cl2 at room temperature gave chloro-substituted phenols in 73-91% yields.

Chemistry Express published new progress about Chlorination. 3964-57-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, COA of Formula: C8H7ClO3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Saha, Arijit; Wu, Chia-Ming; Peng, Rui; Koodali, Ranjit; Banerjee, Subhash published the artcile< Facile Synthesis of 1,3,5-Triarylbenzenes and 4-Aryl-NH-1,2,3-Triazoles Using Mesoporous Pd-MCM-41 as Reusable Catalyst>, Related Products of 5153-70-8, the main research area is triarylbenzene preparation nitrostyrene denitrative cyclotrimerization MCM41 supported palladium catalyst; triazole preparation nitrostyrene denitrative cycloaddition MCM41 supported palladium catalyst.

We report mesoporous nano-Pd-MCM-41 catalyzed rapid and efficient synthesis of 1,3,5-triarylbenzenes via de-nitrative cyclotrimerization of β-nitrostyrenes. All the reactions were very fast and high yielding. The Pd-MCM-41 was also very effective in catalyzing de-nitrative [3+2] cycloaddition of β-nitrostyrenes with TMSN3 to synthesize 4-aryl-NH-1,2,3-triazoles. The catalyst was reused at least up to eight times with min. loss of catalytic activity.

European Journal of Organic Chemistry published new progress about [3+2] Cycloaddition reaction (denitrative). 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Related Products of 5153-70-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Matin, Priyanka; Rahman, Rezaur Md; Huda, Durul; Bakri, Muhammad Khusairy Bin; Uddin, Jamal; Yurkin, Yuriy; Burkov, Andrey; Kuok, Kuok King; Matin, Mohammed Mahbubul published the artcile< Application of synthetic acyl glucopyranosides for white-rot and brown-rot fungal decay resistance in aspen and pine wood>, HPLC of Formula: 17082-09-6, the main research area is acyl glucopyranoside fungi decay resistance wood.

Due to its non-toxicity and environmentally friendly nature, carbohydrate based fatty acid (CFA) esters are encouragingly used as antimicrobials and synthetic intermediates. They also are notably applied in food, surfactant, and pharmaceutical industries. In this respect, Me 2,6-di-O-isopentanoyl-α-D-glucopyranoside (2), synthesized in a single step from Me α-D-glucopyranoside (1), was converted into four other 3,4-di-O-acyl esters (3 – 6). All the newly synthesized CFA esters (2 – 6) were applied for the first time to study decay resistances of aspen (Populus tremula) and pine (Pinus sibirica) wood from decay caused by white-rot (Polyporous versicolor L.ex. Fr.) and brown-rot (Postia placenta (Fr). Cke.) fungi. Most of these CFA esters protected these woods from fungal attack, reduced deterioration, and preserved the weight percentage of woods at a certain point. It is noted that the CFA esters compounds reduced the deterioration and suppressed the weight percentage loss of wood at a certain point and from low to moderate decay resistances against the selected fungi.

BioResources published new progress about Fungi, brown rot. 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, HPLC of Formula: 17082-09-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Xu, Yingying; Huang, Xin; Lv, Guanghui; Lai, Ruizhi; Lv, Songyang; Li, Jianglian; Hai, Li; Wu, Yong published the artcile< Iridium-Catalyzed Carbenoid Insertion of Sulfoxonium Ylides for Synthesis of Quinoxalines and β-Keto Thioethers in Water>, Product Details of C9H7ClO, the main research area is keto thioether green preparation carbenoid insertion annulation water; quinoxaline green preparation carbenoid insertion annulation water.

Sulfoxonium ylides as safe carbene precursors are described for iridium-catalyzed carbene insertions and annulation, providing a facile and green approach to access a variety of quinoxaline derivatives in water. This water-mediated method also allows the preparation of β-keto thioethers under mild condition.

European Journal of Organic Chemistry published new progress about Aromatic diamines Role: RCT (Reactant), RACT (Reactant or Reagent) (ortho). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Product Details of C9H7ClO.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Jolivalt, C.; Neuville, L.; Boyer, F. D.; Kerhoas, L.; Mougin, C. published the artcile< Identification and Formation Pathway of Laccase-Mediated Oxidation Products Formed from Hydroxyphenylureas>, Safety of Methyl 4-chloro-2-hydroxybenzoate, the main research area is laccase oxidation hydroxyphenylurea polyaromatic compound quinone.

Hydroxyphenylureas are the first main metabolites formed in the environment from pesticide and biocide urea compounds Because fungi release potent exocellular oxidases, we studied the ability of laccases produced by the white rot fungus, T. versicolor, to catalyze in vitro the transformation of five hydroxyphenylureas, to identify transformation pathways and mechanisms. Our results establish that the pH of the reaction has a strong influence on both the kinetics of the reaction and the nature of the transformation products. Structural characterization by spectroscopic methods (NMR, mass spectrometry) of eleven transformation products shows that laccase oxidizes the substrates to quinones or to polyaromatic oligomers. Slightly acidic conditions favor the formation of quinones as final transformation products. In contrast, at pH 5-6, the quinones further react with the remaining substrate in solution to give hetero-oligomers via carbon-carbon or carbon-oxygen bond formation. A reaction pathway is proposed for each of the identified products. These results demonstrate that fungal laccases could assist the transformation of hydroxyphenylureas.

Journal of Agricultural and Food Chemistry published new progress about C-C bond formation. 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Safety of Methyl 4-chloro-2-hydroxybenzoate.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Deng, Xiangping; Liu, Renbo; Li, Junjian; Li, Zhongli; Liu, Juan; Xiong, Runde; Lei, Xiaoyong; Zheng, Xing; Xie, Zhizhong; Tang, Guotao published the artcile< Design, synthesis, and preliminary biological evaluation of 3',4',5'-trimethoxy flavonoid salicylate derivatives as potential anti-tumor agents>, Quality Control of 22717-55-1, the main research area is trimethoxy flavonoid salicylate derivative antitumor tubulin mol docking.

According to the pharmacophore combination principle, a set of new 3′,4′,5′-trimethoxy flavonoid salicylate derivatives were designed, synthesized, and evaluated for biol. activity. The cytotoxicity evaluation revealed that compound 10v exhibited higher potency than 5-Fu against HCT-116 cells. Preliminary biol. activity studies showed that compound 10v could inhibit the colony formation and migration of HCT-116 cells. Besides, the Hoechst 33258 staining assay and flow cytometry revealed that treatment with compound 10v induced the apoptosis of HCT-116 cells in a concentration-dependent manner, while it had no effect on their cell cycle. The WB anal. suggested that HIF-1α, tubulin, HK-2, and PFK might be the potential pharmacophore targets of compound 10v. Tubulin was a potential drug target for compound 10v, which was explained by analyzing the crystal structure of compound 10v complexed with tubulin. These results indicated that compound 10v might be a promising anti-tumor agent candidate, deserving further optimization and evaluation.

New Journal of Chemistry published new progress about Antitumor agents. 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Quality Control of 22717-55-1.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics