Tag: M.W=150-200

Gimenez, Rodrigo E.; Serrano, Mariana P.; Alvarez, Rosa Maria S.; Martino, Debora M.; Borsarelli, Claudio D. published the artcile< Fabrication and Characterization of Hollow Microcapsules from Polyelectrolytes Bearing Thymine Pendant Groups for Ultraviolet-B (UVB)-Induced Crosslinking>, Electric Literature of 1592-20-7, the main research area is polyelectrolyte microcapsule thymine UV crosslinking; hollow microcapsules; layer-by-layer method; photo-crosslinking; polyelectrolytes; thymine.

DNA – bioinspired polyelectrolytes poly[vinylbenzylthymine (VBT)-4-vinylbenzyltriethylammonium chloride (VBA)] and poly[vinylbenzylthymine (VBT)-4-vinylphenylsufonate (VPS)] were used for the preparation of hollow microcapsules (HMC) using the layer-by-layer method and CaCO3 microspheres as removable molds. Stable aqueous suspensions of spherical-shaped HMCs with a shell composed of six layers of VBA-based polyelectrolytes were obtained, of approx. (7.0 ± 1.5) μm diameter and a shell thickness of 1 μm. UV-B irradiation of the HMC suspensions induces an efficient crosslinking between adjacent polyelectrolyte chains through the formation of thymine photodimers, such as the cyclobutane pyrimidine dimer (CPD) and the (6-4) pyrimidine-pyrimidone photoproduct (6-4PP). This process resulted in a reduction of the average interstitial mesh size of the HMC shells, modulating their permeability properties and increasing the mech. stability of the HMC without a noticeable modification of size and shape. Thus, the DNA-bioinspired polyelectrolytes are promising materials for the preparation of UVB-responsive HMCs.

ChemPlusChem published new progress about Double-layer capacitance. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Electric Literature of 1592-20-7.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yu, Hao; Wang, Zhenhua; Wu, Ri; Chen, Xiangfeng; Chan, T.-W. Dominic published the artcile< Water-dispersible pH/thermo dual-responsive microporous polymeric microspheres as adsorbent for dispersive solid-phase extraction of fluoroquinolones from environmental water samples and food samples>, Category: chlorides-buliding-blocks, the main research area is polymeric microsphere liquid chromatog mass spectrometry; dispersive solid phase extraction water dispersibility; Environmental samples; Hydrophilic–hydrophobic transition; Liquid chromatography–mass spectrometry; Polymeric microspheres; Water dispersibility; d-SPE.

Multifunctional polymeric microspheres were prepared using hyper-crosslinking chem. combined with surface-initiated atom transfer radical polymerization The synthesized microspheres exhibited good water dispersibility, a high surface area, and pH/thermo dual-responsiveness. Fluoroquinolones (FQs), which contains a hydrophilic piperazine ring and hydrophobic fluorine atoms, were used as target analytes to assess the performance of the microspheres as a sorbent for dispersive solid-phase extraction (d-SPE). The d-SPE exptl. parameters, including extraction time, amount of microspheres, extraction temperature, and sample solution pH, as well as the desorption conditions, were systematically studied. Coupled with LC-MS/MS, an anal. method for anal. of trace-level FQs in water samples was developed and validated. Under optimal conditions, linearity with correlation coefficients (r) of >0.99 was achieved in the concentration range of 0.02-10 μg L-1. The limits of detection and quantification for the selected FQs were 5.0-6.7 and 12-20 ng L-1, resp. High recovery values (93.1%-97.2%), a high enrichment factor (∼180), and good precision (RSD < 8%, n = 6) were obtained for FQ determination in spiked purified water samples. It was proposed that hydrophilic-hydrophobic transition induced by stretching and shrinking of polymer chains under different pH and temperature conditions offered good control of the surface wettability and altered the extraction behavior. The developed method was validated and was successfully applied to the anal. of FQs in environmental water samples, meat and milk samples. These results demonstrated that the water-dispersible polymeric microspheres have good potential for use in separation and extraction techniques. Journal of Chromatography A published new progress about Adsorbents. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Wentao; Huang, Wei; Lin, Qian; Tsai, Mei-Hsuan; Zhang, Rui; Fan, Lijun; Scott, Jack D.; Liu, Guansai; Wan, Jinqiao published the artcile< Development of DNA-compatible hydroxycarbonylation reactions using chloroform as a source of carbon monoxide>, Recommanded Product: 4-Chloro-3-methoxybenzoic acid, the main research area is DNA encoded hydroxycarbonylation aryl halide chloroform; Chloroform; DNA compatible reaction; DNA-encoded library; Hydroxycarbonylation; Palladium catalysis.

A robust palladium-catalyzed hydroxycarbonylation of aryl halides on DNA has been developed. Instead of Mo(CO)6 as a source of carbon monoxide as previously described in the literature, chloroform was used as a surrogate in this report for the purpose of avoiding to use a large excess of molybdenum reagent which is not totally soluble in aqueous reaction mixtures

Bioorganic & Medicinal Chemistry published new progress about Aromatic carboxylic acids Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 85740-98-3 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Recommanded Product: 4-Chloro-3-methoxybenzoic acid.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Qiyu; Zhou, Liang; Fan, Di; Guan, Mingzhao; Ma, Qiaozhi; Li, Song; Ouyang, Xinping; Qiu, Xueqing; Fan, Wei published the artcile< Adsorption-Enhanced Glucan Oligomer Production from Cellulose Hydrolysis over Hyper-Cross-Linked Polymer in Molten Salt Hydrate>, SDS of cas: 1592-20-7, the main research area is adsorption glucan oligomer cellulose molten salt hydrate; cellulose; glucan oligomer; hydrolysis; hyper-cross-linked polymer; reactive adsorption.

Selective saccharification of cellulose into glucose is a critical step for utilization of lignocellulosic biomass. Molten salt hydrates (MSHs) have shown promising performance in selectively converting cellulose into glucose because of the high solubility of cellulose in the solvent. However, the separation of formed glucose from the MSHs is still a grand challenge. To address this issue, we developed a two-step process, where crystalline cellulose is hydrolyzed into short-chain glucan oligomers in MSHs followed by separation and subsequent hydrolysis of the formed oligomers into glucose under mild conditions. The two-step method provides an easy separation for glucan oligomers from the MSHs without sacrificing the selectivity to glucose. Application of the method for crystalline cellulose is, however, limited to a relatively low concentration, 26.2 mg/mL, because of the formation of byproducts in the MSH that facilitate oligomers degradation In this work, reactive adsorption was employed to in situ remove the byproducts formed during cellulose hydrolysis in the MSH. It was found that hyper-crosslinked polymer (HCP) made from the polymerization of 4-vinylbenzyl chloride and divinylbenzene can selectively adsorb 5-hydroxymethylfurfural (5-HMF) and levulinic acid (LA) while showing negligible sugar adsorption in both water and the MSH. With the reactive adsorption approach, byproducts including 5-HMF and LA were removed from the reaction media under reaction conditions, and their neg. effects on oligomer degradation were inhibited. In the presence of the HCP, the obtained glucan oligomer concentration was enhanced from less than 54.2 to 247.1 mg mL-1 when the weight ratio of cellulose was increased to MSH from 1:60 to 1:4, exhibiting an oligomer yield of 69.5%. The HCP can be effectively separated from the reaction media by filtration and regenerated by oxidation with hydrogen peroxide. Application of reactive adsorption with HCP for cellulose hydrolysis in the MSH provides a promising method to produce glucan oligomers and glucose with an improved yield and efficiency.

ACS Applied Materials & Interfaces published new progress about Adsorbents. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, SDS of cas: 1592-20-7.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Suri Babu, Undamatla; Singam, Maneesh Kumar Reddy; Kumar, Muniganti Naveen; Nanubolu, Jagadeesh Babu; Sridhar Reddy, Maddi published the artcile< Palladium-Catalyzed Carbo-Aminative Cyclization of 1,6-Enynes: Access to Naphthyridinone Derivatives>, Formula: C9H5ClO2, the main research area is naphthyridinone preparation; enyne iodoaniline carbo aminative cyclization palladium catalyst.

A general approach to naphthyridinones I [R = H, 8-Me, 7-F, etc.; Ar = Ph, 4-MeC6H4, Bn, etc.; Ar1 = Ph, 4-MeC6H4, 2-thienyl, etc.] was described via Pd-catalyzed annulation of 1,6-enynes with 2-iodoanilines. This protocol represents a rare carbo-aminative annulative cyclization via 6-endo-trig mode, subduing the well documented exo-trig/dig cyclizations. Regioselective aryl palladation of alkyne followed by Heck type intramol. coupling before isomerization were key in realizing this cascade.

Organic Letters published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Formula: C9H5ClO2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ohba, Mai; Oka, Tomoichiro; Ando, Takayuki; Arahata, Saori; Ikegaya, Asaka; Takagi, Hirotaka; Ogo, Naohisa; Owada, Kazuhiro; Kawamori, Fumihiko; Wang, Qiuhong; Saif, Linda J.; Asai, Akira published the artcile< Discovery and synthesis of heterocyclic carboxamide derivatives as potent anti-norovirus agents>, Application of C5H2Cl2O2S, the main research area is heterocyclic carboxamide preparation SAR antiviral.

In this study, synthesis, anti-norovirus activity, and structure-activity relationship (SAR) of a series of heterocyclic carboxamide derivatives I (R3 = 2-thienyl, 2-furyl, 2-thiazolyl, etc.; R4 = H, 6-Cl, 4-Br, etc.) has been described. Heterocyclic carboxamide I (R3 = 5-bromo-thiophen-2-yl; R4 = 6-F) (50% effective concentration (EC50)= 37 μM) was identified using the cytopathic effect reduction assay by the author’s screening campaign. Initial SAR studies suggested the importance of halogen substituents on the heterocyclic scaffold and identified 3,5-di-bromo-thiophene derivative (EC50 = 24 μM) and 4,6-di-benzothiazole derivative (EC50 = 5.6 μM) as more potent inhibitors than I (R3 = 5-bromo-thiophen-2-yl; R4 = 6-F). Moreover, their hybrid compound, 3,5-di-bromo-thiophen-4,6-di-fluoro-benzothiazole, showed the most potent anti-norovirus activity with a EC50 value of 0.53 μM. Further investigation suggested that the hybrid compound might inhibit intracellular viral replication or the late stage of viral infection.

Chemical & Pharmaceutical Bulletin published new progress about Antiviral agents. 31166-29-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C5H2Cl2O2S, Application of C5H2Cl2O2S.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Garcia-Monzon, Irma; Borges-Gonzalez, Jorge; Martin, Tomas published the artcile< Solid-Supported Tetrahydropyran-Based Hybrid Dipeptide Catalysts for Michael Addition of Aldehydes to Nitrostyrenes>, Computed Properties of 5153-70-8, the main research area is tetrahydropyran dipeptide catalyst solid support aldehyde nitrostyrene michael addition.

The heterogenization of homogeneous catalysts onto a solid support is a step towards a more sustainable chem. The recovery and reuse of catalysts is extremely important from a practical, economic and environmental point of view. In this regards, we report a series of polymer-supported tetrahydropyran-based hybrid dipeptides that serve as active catalysts for the enantioselective Michael addition of aldehydes to β-nitrostyrenes. These supported catalysts have been designed considering the optimal anchor position and orientation between the catalyst and the solid support. Addnl., the influence of the linker length on the catalytic efficiency was studied. The catalysts allowed the transformation of a variety of substrates in 76-98% yield and with 94-97% enantiomeric excess. Detailed deactivation studies have provided important information, which allows to increase the useful life of these immobilized catalysts.

Advanced Synthesis & Catalysis published new progress about Asymmetric catalysis. 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Computed Properties of 5153-70-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Li, Na; Liu, Dan; Dai, Jiang-Kun; Wang, Jin-Yi; Wang, Jun-Ru published the artcile< Synthesis and in vitro antibacterial activity of quaternized 10-methoxycanthin-6-one derivatives>, Category: chlorides-buliding-blocks, the main research area is benzyl methoxycanthinone preparation agrochem antibacterial activity SAR; 10-methoxycanthin-6-one; SARs; antibacterial; quaternization.

Background: Based on our previous work, we found that 10-methoxycanthin-6-one displayed potential antibacterial activity and quaternization was an available method for increasing the antibacterial activity. Here, we explored the antibacterial activity of quaternized 10-methoxy canthin-6-one derivatives Methods and Results: Twenty-two new 3-N-benzylated 10-methoxy canthin-6-ones were designed and synthesized through quaternization reaction. The in vitro antibacterial activity against three bacteria was evaluated by the double dilution method. Moreover, the structure-activity relationships (SARs) were carefully summarized in order to guide the development of antibacterial canthin-6-one agents. Two highly active compounds displayed 8-fold superiority (MIC = 3.91 μg/mL) against agricultural pathogenic bacteria R. solanacearum and P. syringae compared to agrochem. streptomycin sulfate, and showed potential activity against B. cereus. Moreover, these two compounds exhibited good “”drug-like”” properties, low cytotoxicity, and no inhibition on seed germination. Conclusions: This work provides two new effective quaternized canthin-6-one derivatives as candidate bactericide, promoting the development of natural-sourced bactericides and preservatives.

Molecules published new progress about Agrochemical antibacterial agents. 611-19-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H6Cl2, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Weidlich, Tomas; Kamenicka, Barbora; Melanova, Klara; Cicmancova, Veronika; Komersova, Alena; Cermak, Jiri published the artcile< Hydrodechlorination of different chloroaromatic compounds at room temperature and ambient pressure-differences in reactivity of Cu- and Ni-based Al alloys in an alkaline aqueous solution>, Application of C7H4ClF3O, the main research area is chloroarom compound copper nickel aluminum alloy hydrodechlorination.

It is well known that the hydrodechlorination (HDC) of chlorinated aromatic contaminants in aqueous effluents enables a significant increase in biodegradability. HDC consumes a low quantity of reactants producing corresponding non-chlorinated and much more biodegradable organic compounds Two commonly used precious metals free Al alloys (Raney Al-Ni and Devarda’s Al-Cu-Zn) were compared in reductive action in an alk. aqueous solution Raney Al-Ni alloy was examined as a universal and extremely effective HDC agent in a diluted aqueous NaOH solution The robustness of Raney Al-Ni activity is illustrated in the case of HDC of polychlorinated aromatic compounds mixture in actual waste water. In contrast, Devarda’s Al-Cu-Zn alloy was approved as much less active for HDC of the tested chlorinated aromatic compounds, but with a surprisingly high selectivity on cleavage of C-Cl bonds in the meta and sometimes the ortho position in chlorinated aniline and sometimes chlorinated phenol structures. The reaction of both tested alloys with chlorinated aromatic compounds in the aqueous NaOH solution is accompanied by dissolution of aluminum. Dissolved Al in the alk. HDC reaction mixture is very useful for subsequent treatment of HDC products by coagulation and flocculation of Al(OH)3 caused by simple neutralization of the alk. aqueous phase after the HDC reaction.

Catalysts published new progress about Biodegradability. 35852-58-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H4ClF3O, Application of C7H4ClF3O.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yan, Jingling; Li, Taihang; Wang, Zhen; Gao, Lianxun; Ding, Mengxian published the artcile< Hydrazine-based polyimides from isomeric bis(chlorophthalimide)s>, Related Products of 118-45-6, the main research area is hydrazine isomeric dichloro bisphthalimide thiobisbenzenethiol polyimide thermal mech property.

3,3′-Dichloro-N,N’-bisphthalimide (3,3′-DCBPI), 3,4′-dichloro-N,N’-bisphthalimide (3,4′-DCBPI), and 4,4′-dichloro-N,N’-bisphthalimide (4,4′-DCBPI) were synthesized from 3- or 4-chlorophthalic anhydrides and hydrazine in glacial acetic acid. The yield of 3,3′-DCBPI (90%) was much higher than that of 4,4′-DCBPI (33%) because of the better stability of the intermediate, 3-chloro-N-aminophthalimide, and 3,3′-DCBPI. A series of hydrazine-based polyimides were prepared from isomeric DCBPIs and 4,4′-thiobisbenzenethiol (TBBT) in N,N-dimethylacetamide in the presence of tributylamine. Inherent viscosity of these polymers was in the range of 0.51-0.69 dL/g in 1-methyl-2-pyrrolidinone (NMP) at 30 °C. These polyimides were soluble in 1,1,2,2-terachloroethane, NMP, and phenols. The 5% weight-loss temperatures (T5%s) of the polymers were near 450 °C in N2. Their glass-transition temperatures (Tgs) determined by dynamic mech. thermal anal. and differential scanning calorimetry increased according to the order of polyimides based on 4,4′-DCBPI, 3,4′-DCBPI, and 3,3′-DCBPI. The hydrolytic stability of these polymers was measured under acid, basic, and neutral conditions and the results indicated that the order was 3,3′-DCBPI/TBBT > 3,4′-DCBPI/TBBT > 4,4′-DCBPI/TBBT.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about Elongation at break. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Related Products of 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics