Tag: M.W=150-200

Khairnar, Pankaj V.; Su, Yin-Hsiang; Chen, Yung-Chang; Edukondalu, Athukuri; Chen, Yi-Ru; Lin, Wenwei published the artcile< Organophosphane-Catalyzed Direct β-Acylation of 4-Arylidene Pyrazolones and 5-Arylidene Thiazolones with Acyl Chlorides>, Quality Control of 17082-09-6, the main research area is oxoarylidene pyrazolone preparation diastereoselective crystal structure mol; arylidene pyrazolone acyl chloride acylation organophosphane catalyst; oxo arylidene thiazolone preparation diastereoselective crystal structure mol; thiazolone arylidene acyl chloride acylation organophosphane catalyst.

An efficient method for the direct β-acylation of arylidene pyrazolones and thiazolones with acyl chlorides in the presence of a base catalyzed by organophosphanes was reported. A variety of oxoarylidene pyrazolones I [R1 = Me, i-Pr, Ph, etc.; R2 = Ph, 4-MeOC6H4, 4-FC6H4, etc.; R3 = Ph, 4-ClC6H4, 2-thienyl, etc.; R4 = Me, Ph, 2-thienyl, etc.] and oxoarylidene thiazolones II [R5 = Ph, 4-ClC6H4, 2-MeC6H4, etc.] were prepared under metal-free and mild conditions via a tandem phospha-Michael addition/O-acylation/intramol. cyclization/rearrangement sequence. Mechanistic investigations revealed that the reaction was highly stereospecific to provide exclusively cis-isomers and the methodol. could also be scaled up with similar efficacy.

Organic Letters published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Quality Control of 17082-09-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kumar, Balagani Sathish; Negi, Arvind S. published the artcile< A frank synthesis of alkyl-aryl ethers from 2-halobenzaldehydes and aromatic olefins without transition metal co-catalyst and ligand>, COA of Formula: C8H7ClO2, the main research area is alkyl aryl ether preparation halobenzaldehyde aromatic olefin.

An efficient synthesis of alkyl ethers was developed for o-deactivated aryl halides and 1-halotetralenes. The method shows good regioselectivity towards ortho substituted halides. Alkali metal carbonates (Li2CO3/Na2CO3/K2CO3/Cs2CO3) were used without a transition metal co-catalyst and ligand. The method is simple, straight-forward and proceeds to afford products in good isolated yields. The method holds potential for future applications in organic synthesis.

Tetrahedron Letters published new progress about Alkyl aryl ethers Role: SPN (Synthetic Preparation), PREP (Preparation). 53581-86-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO2, COA of Formula: C8H7ClO2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Barn, David R.; Morphy, J. Richard published the artcile< Solid-Phase Synthesis of Cyclic Imides>, SDS of cas: 118-45-6, the main research area is imide cyclic combinatorial library solid phase synthesis; phthalimidoethylisoquinoline analog combinatorial library solid phase synthesis; isoquinoline phthalimidoethyl analog preparation.

A cyclative cleavage strategy for the synthesis of cyclic imides on a polystyrene resin is described. After optimization of the cleavage conditions, a small array of succinimides and phthalimides was synthesized. The methodol. was then applied to a drug discovery project, in which it was used to synthesize a new class of δ-opioid receptor ligands, analogs of the isoquinoline I, by both automated and manual methods.

Journal of Combinatorial Chemistry published new progress about Combinatorial library. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, SDS of cas: 118-45-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wei, Haibing; Fang, Xingzhong; Han, Ying; Hu, Benlin; Yan, Qing published the artcile< Synthesis and characterization of poly(thioether ether sulfone imide)s derived from isomeric bis(chlorophthalimide)s and bis(4-mercaptophenyl) sulfone>, Category: chlorides-buliding-blocks, the main research area is polyether polyimide polysulfone polythioether synthesis thermal mech property.

A series of isomeric bis(chlorophthalimide)s (BCPIs) were conveniently prepared from 3-chlorophthalic anhydride, 4-chlorophthalic anhydride, and mixtures thereof. Polymerization of BCPIs with bis(4-mercaptophenyl) sulfone (BMPS) proceeded smoothly in the presence of tributylamine, from which a class of isomeric poly(thioether ether sulfone imide)s (PTESIs) with inherent viscosities of 0.45-0.82 dL/g were obtained. The solubility, thermal stability, and mech. properties of these polymers were characterized. Compared to the PTESIs derived from single BCPIs, i.e., 3,3′-, 3,4′-, or 4,4′-BCPIs, the PTESIs derived from mixed BCPIs showed better solubility and higher storage modulus. These PTESIs also demonstrated good thermal stability, giving only 5% weight loss at temperature of 490° in nitrogen atm. The glass transition temperatures (T gs) of these isomeric PTESIs were between 242 and 265°, and were increased with increasing of the ratio of 3-chlorophthalimide unit in the polymer backbone.

European Polymer Journal published new progress about Complex modulus, tan δ. 118-45-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H3ClO3, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhao, Zhe; Tian, Xinzhe; Tang, Peichen; Ren, Yun-Lai; Zhao, Shuang; Zheng, Xianfu; Cheng, Xinqiang published the artcile< Autocatalytic Friedel-Crafts Acylation of Arenes without Additional Catalyst and Additive>, Formula: C9H7ClO, the main research area is acyl chloride arene autocatalysis regioselective Friedel Crafts acylation; aryl ketone preparation.

A new and autocatalytic method was developed for Friedel-Crafts acylation of arenes without addnl. catalyst and additive. A series of electron-rich arenes underwent the acylation to give the targeted product in low to high yields by using aryl, alkyl and vinyl acyl chlorides as the acylating reagent, which gave an effective method for the preparation of diaryl ketones, alkyl aryl ketones and α,β-unsaturated ketones. Preliminary mechanistic investigation suggested that the present acylation displayed an induction period and a sigmoid kinetic profile characteristic of autocatalytic systems, and the resulting H+ played a role of the catalyst.

ChemistrySelect published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 17082-09-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H7ClO, Formula: C9H7ClO.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chang, Chia-Lin published the artcile< Synthesis and structural pattern recognition of 5-(2'-alkoxycarbonyl-substituted phenoxy)furfural derivatives>, Computed Properties of 22717-55-1, the main research area is phenoxyfurfural phenoxyfurancarboxylate preparation structural recognition analysis NMR mass spectra; nitrofurfural phenol nucleophilic substitution.

The Et 5-(2′-alkoxycarbonyl-substituted phenoxy)furan-2-carboxylates e.g. I, showed good anti-platelet aggregation, anti-allergic and anti-inflammatory activities. A series of 5-(2′-alkoxycarbonyl-substituted phenoxy)furfurals e.g. II, were prepared for comparing the above activities. The objectives of this research are the synthesis and structural pattern recognition of 5-(2′-alkoxycarbonyl-substituted phenoxy)furfurals. The Silica Gel 60 column chromatog. method was employed to sep. and purify pure 5-(2′-alkoxycarbonyl-substituted phenoxy)furfurals, by three solvent systems. For the structure elucidation of 5-(2′-alkoxycarbonyl-substituted phenoxy)furfurals, four spectroscopic methods were used: electron impact mass (EI-MS), UV-VIS, IR and NMR spectrometers. With the help of spectrometers, investigations can be performed on spectroscopic data. A simple methodol. for recognizing structural patterns was carried out with the aid of statistical anal. designed to establish the classification model of the structural skeleton in this research. It was found that Et phenoxyfuran-2-carboxylate derivatives and phenoxyfurfural derivatives, have similar chem. profiles and are clustered into one group. The pattern plots revealed valuable information and showed good correlation between Et phenoxyfuran-2-carboxylate derivatives and phenoxyfurfural derivatives These findings correlate directly with the resulting spectroscopic data. These results with those obtained by EI-MS and NMR patterns give insight into a reliable pattern recognition for determining the skeletons of Et phenoxyfuran-2-carboxylate derivatives and phenoxyfurfural derivatives

Chemical & Pharmaceutical Bulletin published new progress about Electron ionization mass spectra. 22717-55-1 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Computed Properties of 22717-55-1.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tsagdi, Artemis; Druvari, Denisa; Panagiotaras, Dionisios; Avramidis, Pavlos; Bekiari, Vlasoula; Kallitsis, Joannis K. published the artcile< Polymeric coatings based on water-soluble trimethylammonium copolymers for antifouling applications>, COA of Formula: C9H9Cl, the main research area is water soluble trimethylammonium copolymer coating antifouling application; antifouling coatings; aquaculture nets; crosslinked polymeric materials; high-pressure cleaning; quaternary trimethylammonium compounds; water-soluble copolymers.

Crosslinked polymeric materials based on a quaternary trimethylammonium compound were developed and evaluated as potential antifouling coatings. For this purpose, two water-soluble random copolymers, poly(4-vinylbenzyltrimethylammonium chloride-co-acrylic acid) P(VBCTMAM-co-AAx) and poly(N,N-dimethylacrylamide-co-glycidylmethacrylate) P(DMAm-co-GMAx), were synthesized via free radical polymerization A water based approach for the synthesis of P(VBCTMAM-co-AAx) copolymer was used. Coatings of the complementary reactive copolymers in different compositions were obtained by curing at 120°C for one day and were used to coat aquaculture nets. These nets were evaluated in respect to their release rate using Total Organic Carbon (TOC) and Total Nitrogen (TN) measurements. Finally, the antifouling efficacy of these newly-composed durable coatings was investigated for 14 days in accelerated conditions. The results showed that this novel polymeric material provides contact-killing antifouling activity for a short time period, whereas it functions efficiently in biofouling removal after high-pressure cleaning.

Molecules published new progress about Antifouling agents. 1592-20-7 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H9Cl, COA of Formula: C9H9Cl.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Bharathi Priya, Velumani; Ramya, Subramani; Uthayanila, Selvarasu; Karthikeyan, Parasuraman published the artcile< A development of a reusable copper supported imidazolium functionalized ionic liquid catalyzed asymmetric Michael addition reaction>, Computed Properties of 5153-70-8, the main research area is cyclohexanone nitrostyrene copper ionic liquid enantioselective Michael addition; nitro phenylethyl cyclohexanone preparation green chem.

An eco-friendly copper supported Imidazolium functionalized ionic liquid [[Gmim]Cl-Cu (II)] was used as green catalyst in solvent free asym. Michael addition at 25°C. This technique covers simplified product isolation, high conversion and catalyst recycling.

Journal of the Indian Chemical Society published new progress about Cyclohexanones Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 5153-70-8 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H6ClNO2, Computed Properties of 5153-70-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Terasaki, Masanori; Makino, Masakazu published the artcile< Disinfection by-products of para-hydroxybenzoate esters (parabens): synthesis and mass spectrometric study>, Name: Methyl 3-chloro-4-hydroxybenzoate, the main research area is paraben chlorination sulfuryl chloride; disinfection drinking water purification byproduct synthesis.

A simple and efficient procedure for the chlorination of para-hydroxybenzoate esters (parabens) with sulfuryl chloride is described. Fourteen monochlorinated or dichlorinated parabens were synthesized and their mass spectrometric characteristics were determined This work enabled the definitive identification and quantification of the chlorinated parabens in environmental samples.

Journal of Health Science published new progress about Chlorination. 3964-57-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO3, Name: Methyl 3-chloro-4-hydroxybenzoate.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gung, Benjamin W.; Smith, Daniel T.; Wolf, Mark A. published the artcile< Evidence for synclinal transition state in the reactions of aromatic aldehydes with α-(alkoxy)allylstannanes>, Synthetic Route of 53581-86-5, the main research area is aldehyde aromatic reaction alkoxyallylstannane stereochem; transition state structure aldehyde reaction alkoxyallylstannane; ether enol preparation stereoselective.

Unlike aliphatic aldehydes, aromatic aldehydes produce greater than 95% of syn-(Z)-enol ether when treated with α-(alkoxy)allylstannanes in the presence of BF3·Et2O. However, in the presence of TiCl4, the reaction of p-chloro-o-methoxybenzaldehyde with α-(alkoxy)crotylstannane produced predominantly the syn-(E) isomer.

Tetrahedron published new progress about Aryl aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 53581-86-5 belongs to class chlorides-buliding-blocks, and the molecular formula is C8H7ClO2, Synthetic Route of 53581-86-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics