Tag: M.W=150-200

Chlorinated organic compounds are found in nearly every class of biomolecules. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Reference of 349-88-2.

Li, Long;Li, Jiao-Zhe;Sun, Yong-Bin;Luo, Chun-Mei;Qiu, Hui;Tang, Keqi;Liu, Hongxin;Wei, Wen-Ting research published 《 Visible-Light-Catalyzed Tandem Radical Addition/1,5-Hydrogen Atom Transfer/Cyclization of 2-Alkynylarylethers with Sulfonyl Chlorides》, the research content is summarized as follows. A novel visible-light-catalyzed tandem radical addition/1,5-hydrogen atom transfer/cyclization cascade of 2-alkynylarylethers 2-(CHC)-3-R-4-R¹-C₆H₂OCH(R²)R³ (R = H, Me, Cl, C(O)OMe, etc.; R¹ = H, C(O)OMe; R² = Me, Et, Ph; R³ = Me, Et; R²R³ = -(CH2)5-, -(CH2)4-, -(CH2)3OCH2-) with sulfonyl chlorides R⁴S(O)₂Cl (R⁴ = Ph, 4-bromophenyl, 4-methylphenyl, 4-methoxyphenyl, thiophen-2-yl) in 2-methyltetrahydrofuran was developed under photocatalyst- and additive-free conditions. This reaction relies on unique energy transfer and solvent-radical relay strategies to generate sulfonyl radicals for the preparation of a series of sulfonyl-functionalized dihydrobenzofurans I in moderate to high yields catalyzed by visible light or solar radiation.

Reference of 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Application of C6H4ClFO2S.

Li, Qian;Zhu, Haibo;Liu, Yishuai;Yang, Liu;Fan, Qiangwen;Xie, Zongbo;Le, Zhang-Gao research published 《 Copper-assisted preparation of pyridinyl sulfonate esters from hydroxypyridines and sodium sulfinates》, the research content is summarized as follows. An efficient and powerful copper-assisted method for the effective conversion of a broad range of hydroxypyridines I (R = 2-OH-6-Me, 3-OH, 2-NO₂-3-OH, etc.) and sodium sulfinates R¹SO₂Na (R¹ = Et, 4-methylphenyl, 2-naphthyl, etc.) into their corresponding pyridinyl tosylates II was developed. Key features of this base- and ligand-free protocol include using the cheap and readily available CuBr₂ as a medium and the use of sodium sulfinates as formal sulfonylation reagents. A variety of functional pyridinyl tosylates could be formed with good yields, which can easily be converted into C-C and C-N bond-containing compounds

Application of C6H4ClFO2S, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Formula: C6H6BClO2.

Li, Shuai;Li, Xin-yang;Zhang, Ting-jian;Zhu, Ju;Liu, Kai-li;Wang, De-pu;Meng, Fan-hao research published 《 Novel 4,5-dihydrospiro[benzo[c]azepine-1,1′-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation》, the research content is summarized as follows. To further explore the research of novel PARP-1 inhibitors, design and synthesis of a series of novel 4,5-dihydrospiro[benzo[c]azepine-1,1′-cyclohexan]-3(2H)-one derivatives I (R = H, 2-Cl, 3-F, etc.) PARP-1 inhibitors based on the author’s previous research is reported. Most compounds displayed certain antitumor activities against four tumor cell lines (A549, HepG2, HCT-116, and MCF-7). Specifically, the candidate compound I (R = 2-F) possessed strong anti-proliferative potency toward A549 cells with the IC₅₀ value of 2.01μM and showed low toxicity to lung cancer cell line. And the in vitro enzyme inhibitory activity of compound I (R = 2-F) was better than rucaparib. Mol. docking studies provided a rational binding model of the above compound in complex with rucaparib. The following cell cycle and apoptosis assays revealed that this compound could arrest cell cycle in the S phase and induce cell apoptosis and western blot anal. further showed that it could effectively inhibit the PAR’s biosynthesis and was more effective than rucaparib. Overall, based on the biol. activity evaluation, compound I (R = 2-F) could be a potential lead compound for further developing novel amide PARP-1 inhibitors.

Formula: C6H6BClO2, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: 3-Chlorophenylacetic acid.

Li, Shu-Sen;Wang, Jianbo research published 《 Cu(I)/Chiral Bisoxazoline-Catalyzed Enantioselective Sommelet-Hauser Rearrangement of Sulfonium Ylides》, the research content is summarized as follows. Catalytic asym. thia-Sommelet-Hauser rearrangement of sulfonium ylides remains a great challenge due to its multistep reaction mechanism involving metal carbene formation, proton transfer, and [2,3]-sigmatropic rearrangement. In particular, the key problem of such reactions is the differentiation of the enantiotopic lone pair electrons of sulfur, which generates the sulfonium ylide intermediate bearing chirality on the sulfur atom. With a modified chiral bisoxazoline ligand, we developed a Cu(I)-catalyzed asym. thia-Sommelet-Hauser rearrangement with good to excellent enantioselectivities. Mechanistic studies provide insights into the details of the reaction mechanism.

Name: 3-Chlorophenylacetic acid, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Quality Control of 1878-65-5.

Li, Wei-Yi;Ni, Wei-Wei;Ye, Ya-Xi;Fang, Hai-Lian;Pan, Xing-Ming;He, Jie-Ling;Zhou, Tian-Li;Yi, Juan;Liu, Shan-Shan;Zhou, Mi;Xiao, Zhu-Ping;Zhu, Hai-Liang research published 《 N-monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation》, the research content is summarized as follows. A urease inhibitor with good in vivo profile is considered as an alternative agent for treating infections caused by urease-producing bacteria such as Helicobacter pylori. Here, we report a series of N-monosubstituted thioureas, which act as effective urease inhibitors with very low cytotoxicity. One compound () was evaluated in detail and shows promising features for further development as an agent to treat H. pylori caused diseases. Excellent values for the inhibition of against both extracted urease and urease in intact cell were observed, which shows IC₅₀ values of 0.16 ± 0.05 and 3.86 ± 0.10μM, being 170- and 44-fold more potent than the clin. used drug AHA, resp. Docking simulations suggested that the monosubstituted thiourea moiety penetrates urea binding site. In addition, is a rapid and reversible urease inhibitor, and displays nM affinity to urease with very slow dissociation (k_off=1.60 × 10^-3 s^-1) from the catalytic domain.

Quality Control of 1878-65-5, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Recommanded Product: 4-Fluorobenzene-1-sulfonyl chloride.

Li, Wen;Zhang, Cheng;Zhang, Hong-en;Dong, Ru;Liu, Jing-ying;Wang, Chun-meng;Wang, Min;Wang, Yu-wei;Wang, Chao;Zhang, Yan;Shi, Lei;Xu, Yong;Sun, Li-Ping research published 《 Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors》, the research content is summarized as follows. Bromodomain-containing protein 4 (BRD4), which is a member of the bromodomain and extra-terminal domain (BET) family, plays an important role in the regulation of gene expression as the “reader” of epigenetic regulation. BRD4 has become a promising target to treat cancer, because the up-regulation of BRD4 expression is closely associated with the occurrence and development of various cancers. At present, several BRD4 inhibitors are in clin. trials for cancer therapy, but no BRD4 inhibitors are on the market. Here, we designed and synthesized a series of compounds bearing pyrrolo[4,3,2-de]quinolin-2(1H)-one scaffold through structural modification of natural products ammosamide B, which is a natural pyrroloquinoline derivative reported for its potential antitumor activity. All target compounds were evaluated for their BRD4 BD1 inhibition activities via the protein thermal shift assays or AlphaSceen assay. The representative compound 49 showed potent activity (IC50 = 120 nM). The co-crystal of compound 49 with BRD4 BD1 was solved to study the structure activity relationship, which showed that 49 could combine with the acetyl lysine binding site and formed a hydrogen bond with the conserved residue Asn140. The results demonstrate that compound 49 is worthy of further investigation as a promising BRD4 inhibitor.

Recommanded Product: 4-Fluorobenzene-1-sulfonyl chloride, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Quality Control of 3900-89-8.

Li, Xin;Liu, Yunxia;Zhang, Lizhi;Dong, Yunhui;Liu, Qing;Zhang, Daopeng;Chen, Lei;Zhao, Zengdian;Liu, Hui research published 《 A novel electromagnetic mill promoted mechanochemical solid-state Suzuki-Miyaura cross-coupling reaction using ultra-low catalyst loading》, the research content is summarized as follows. The Nobel-prize-winning Suzuki-Miyaura cross-coupling (SMC) is a practical and attractive strategy for the construction of C-C bonds in both academic and industrial settings. However, the development of solid-state SMC reactions remains extremely scarce. Herein, authors report an electromagnetic mill (EMM) promoted solid-state SMC reaction using ultra-low palladium loading (0.05 mol%) without any liquid mol. dispersants. This protocol exhibits substantially broadened substrate scope, good functional group tolerance, efficient gram-scale synthesis and, especially, relatively high yields. The EMM conditions can suppress high aggregation of catalyst and accelerate the mixture of solid reactants, which might be the key for excellent efficiency. The utility of this strategy was exemplified in the modification of photoluminescent mols., cross-coupling of slightly soluble compounds and synthesis of several important bioactive mols. This solid-state EMM-SMC will be potentially developed into industrially attractive and environmentally friendly routes, and the EMM system developed in this study could unlock broad areas of chem. space for solvent-free solid-state metal-catalyzed synthesis of valuable targets in various scientific fields.

3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Quality Control of 3900-89-8

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Electric Literature of 6334-18-5.

Li, Xin-Ran;Li, Wan-Di;Wei, Wen-Ting;Fan, Juan;Liu, Zhong-Wen;Shi, Xian-Ying research published 《 Sequential Cobalt/Rhodium-Catalyzed Tandem Cyclization of Aromatic Aldehydes with Acrylates for Preparing 3-Substituted Phthalides in Oxygen Atmosphere and Neat Water》, the research content is summarized as follows. Metal-catalyzed C-H activation/tandem reactions of aromatic acids and functionalized alkenes is profound for constructing phthalide skeleton. However, most of these reactions employ stoichiometric amounts of metal additives and metal oxidants/toxic organic solvents. Herein, a sequential cobalt/rhodium-catalyzed tandem cyclization of aromatic aldehydes and acrylates for preparing 3-substituted phthalides in one pot has been described. This protocol features the use of water as a sustainable solvent and oxygen as the singular oxidant free of any additives. The use of aromatic aldehydes instead of aromatic acids as starting materials renders this route high atom economy, and the formation of water as a sole byproduct makes this process practical and environmentally benign.

6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Electric Literature of 6334-18-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Formula: C6H6BClO2.

Li, Xin-yang;Qian, Xin-hua;Zhu, Ju;Li, Yu-heng;Lin, Qi-qi;Li, Shuai;Xue, Wen-han;Jian, Ling-yan;Meng, Fan-hao research published 《 Synthesis and evaluation of novel HER-2 inhibitors to exert anti-breast cancer ability through epithelial-mesenchymal transition (EMT) pathway》, the research content is summarized as follows. In this study, two series of (E)-N-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methyl)anilines I [R = H, 2-F, 3-Br, etc.] and (E)-4-((5-phenyl-1H-indol-1-yl)methyl)-2-(4-(trifluoromethyl)styryl)azoles II synthesized and tested as novel HER-2 inhibitors to exert anti-breast cancer ability through epithelial-mesenchymal transition (EMT) pathway. Herein, screened out the most potential compound I [R = 4-Br] with HER-2 pos. breast cancer cells through MTT assays, which possessed low toxicity on normal cells (MCF7-10A). Subsequently, wound healing, transwell, western blotting, and immunofluorescence experiments were performed, and it was found that compound compound I [R = 4-Br] could suppress cell migration by inhibiting the phosphorylation of HER-2 and affecting the expression of EMT-related proteins. Moreover, the SKBR3 orthotopic xenograft model confirmed that compound I [R = 4-Br] was more effective than Mubritinib in inhibiting the proliferation of cancer cells. In general, compound I [R = 4-Br] was a potential HER-2 inhibitor in treating breast cancer, which may be of great significance for developing and improving HER-2 small mol. inhibitors.

3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., Formula: C6H6BClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Recommanded Product: (2-Chlorophenyl)boronic acid.

Lee, Je-Heon;Kim, Subin;Jin, Mi Sun;Kim, Yong-Chul research published 《 Discovery of substituted indole derivatives as allosteric inhibitors of m⁶A-RNA methyltransferase, METTL3 -14 complex》, the research content is summarized as follows. In this study, the discovery of the first allosteric inhibitor of the METTL3-14 complex I = [R¹ = H, CH₃; R² = (4-methoxycarbonylphenoxy), (4-carbamoylphenoxy), (4-carboxyphenoxy), etc.] and II [R³ = 4-Cl-Ph, 4-F-phenyl; R⁴ = Ph, benzyl, [4-(3,5-dichlorophenyl)phenyl], etc] was described based on structure-activity relationship (SAR) and optimization studies of the hit compound, 4-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-ethoxy]benzoic acid. Compound II [R³ = 4-F-phenyl; R⁴ = [4-(3,5-dichlorophenyl)phenyl]] was optimized throughout the modifications of 4 different regions of the structure, and it displayed potent enzyme inhibitory activity of the METTL3-14 complex (IC₅₀ = 2.81μM) and an antiproliferative effect in the AML cell lines by suppressing the m6A level of mRNA. The inhibition mechanism and binding mode of II [R³ = 4-F-phenyl; R⁴ = [4-(3,5-dichlorophenyl)phenyl]], were based on the interaction of the reversible and noncompetitive inhibitory profile at the allosteric site along with selectivity for the METTL3-14 complex relative to each subunit enzyme or truncated complex enzyme.

Recommanded Product: (2-Chlorophenyl)boronic acid, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics