Tag: 100-200

On December 31, 2002, Costantino, Luca; Ferrari, Anna Maria; Gamberini, Maria Cristina; Rastelli, Giulio published an article.Formula: C7H6ClNO2 The title of the article was Nitrophenyl Derivatives as Aldose Reductase Inhibitors. And the article contained the following:

Nitrophenyl derivatives were recently discovered as a new class of ALR2 inhibitors by means of docking and database screening of the National Cancer Institute database of organic mols. The nitro group was predicted to bind to the Tyr48 and His110 active site residues of the enzyme, the site where acidic ALR2 inhibitors such as carboxylic acids bind in their anionic form. Given the novelty of these compounds, we decided to expand their structure-activity relationships by synthesizing and testing a series of derivatives and the corresponding compounds having a carboxylic group instead of the nitro moiety; the results obtained were rationalized by means of docking and mol. dynamics simulations. On the whole there is an agreement between inhibitory data and the results of mol. modeling experiments, supporting the hypothesized binding mode of these compounds The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Formula: C7H6ClNO2

The Article related to aldose reductase inhibitor nitrophenyl derivative preparation, Pharmacology: Structure-Activity and other aspects.Formula: C7H6ClNO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Unger, John B.; Lipshutz, Bruce H. published an article in 2007, the title of the article was Nickel-in-charcoal.COA of Formula: C7H6ClF And the article contains the following content:

Properties and applications of nickel-in-charcoal, a heterogeneous catalyst that has been applied to a number of group 10 transition metal mediated cross-coupling reactions are reviewed. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).COA of Formula: C7H6ClF

The Article related to review nickel preparation property reactivity safety, Inorganic Chemicals and Reactions: Reviews and other aspects.COA of Formula: C7H6ClF

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 12, 2014, Wang, Bin; Cancilla, John C.; Torrecilla, Jose S.; Haick, Hossam published an article.Electric Literature of 35444-44-1 The title of the article was Artificial Sensing Intelligence with Silicon Nanowires for Ultraselective Detection in the Gas Phase. And the article contained the following:

The use of molecularly modified Si nanowire field effect transistors (SiNW FETs) for selective detection in the liquid phase was successfully demonstrated. In contrast, selective detection of chem. species in the gas phase was rather limited. The application of artificial intelligence on deliberately controlled SiNW FET device parameters can provide high selectivity toward specific volatile organic compounds (VOCs). The obtained selectivity allows identifying VOCs in both single-component and multicomponent environments as well as estimating the constituent VOC concentrations The effect of the structural properties (functional group and/or chain length) of the mol. modifications on the accuracy of VOC detection is presented and discussed. The reported results have the potential to serve as a launching pad for the use of SiNW FET sensors in real-world counteracting conditions and/or applications. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Electric Literature of 35444-44-1

The Article related to volatile organic sensor silicon nanowire fet artificial intelligence, Organic Analytical Chemistry: Detections and other aspects.Electric Literature of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 30, 2008, Wang, Qiong; Wang, Fang; Kou, Ying-wei; Chen, Qiang published an article.Category: chlorides-buliding-blocks The title of the article was QSAR model of EC50 of photobacterium phosphoreum for benzene derivatives using GFA. And the article contained the following:

MS Modeling 4.0 from Accelrys Company was used to calculate diverse mol. descriptors of 100 data, which are EC50 of photobacterium phosphoreum for benzene derivatives QSAR predictive models were built by GFA method using selected descriptors. Comparing the top five models, results indicated that they were almost common, with equation 1 as the best predictive model. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Category: chlorides-buliding-blocks

The Article related to photobacterium benzene derivative toxicity qsar gfa, Toxicology: Methods (Including Analysis) and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 31, 1983, Naganuma, Masayuki; Ohtsu, Yutaka; Katsumura, Yoshio; Matsuoka, Masahiro; Morikawa, Yoshihiro; Tanaka, Muneo; Mitsui, Takeo published an article.Category: chlorides-buliding-blocks The title of the article was Analysis of subsidiary colors in Red Number 204 and its purification. Development of non-allergenic Red Number 204. And the article contained the following:

Red Number 204 (Lake Red CBA) [5160-02-1], used for make-up products including lipstick, was analyzed for its organic impurities. These impurities were isolated by high-performance liquid chromatog. and their structural formulas were confirmed by various anal. methods. Many kinds of aromatic azo compounds (subsidiary colors) were found. The subsidiary colors were 11 kinds including Sudan 1. These subsidiary colors and the related compounds were synthesized for use as the standard samples. The subsidiary colors in Lake Red CBA showed pos. results with the modified guinea pig maximization test indicating that each of them was a contact sensitizer, while Lake Red CBA itself was not. Lake Red CBA synthesized with C acid  [88-53-9] from which aromatic amines were removed contained no subsidiary color. When Lake Red CBA was synthesized with the purified C acid to which 3 types of the typical aromatic amines were added in fixed quantity, the corresponding aromatic azo compounds were produced in proportion to the added amounts of aromatic amines. The preparation of Sudan III, Orange II, Quinoline Yellow WS, Quinizarin Green SS, etc., free from contact sensitive impurities, for use in cosmetic products is discussed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Category: chlorides-buliding-blocks

The Article related to allergy red 204 cosmetic, sensitizer lake red cba, Essential Oils and Cosmetics: General and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 1, 1996, Cantegril, Richard; Mortier, Jacques; Croisat, Denis; Peignier, Raymond published a patent.SDS of cas: 452-75-5 The title of the patent was Preparation of fungicidal 3-phenylpyrazole derivatives for treating propagative plant stock.. And the patent contained the following:

The fungicides (preparation given) are 3-phenylpyrazole derivatives I [ R1-R5 = H, halo, nitro, alkyl; Y= halo, nitro, etc.; Z= H, halo, C(:Z1)Z2, phosphoryl, etc.; Z1 = O, S, etc.; Z2 = H, halo, OH, SH, CN, etc.]. I is useful for protecting propagative plant stock from fungal diseases. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).SDS of cas: 452-75-5

The Article related to pyrazole derivative preparation fungicide, Agrochemical Bioregulators: Microbial and other aspects.SDS of cas: 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Hahn, Elliot F.; Fishman, Jack; Heilman, Richard D. published an article in 1975, the title of the article was Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists.Application of 5034-06-0 And the article contains the following content:

A series of 11 title compounds was prepared from naloxone [465-65-6] and naltrexone [16590-41-3] by the Wittig reaction, or by reaction with sulfur ylides or alkyllithium reagents. Most of the derivatives had oral potencies superior to the parent compounds in hot plate and tail clip tests in mice. 6-Desoxy-6-methylenenaloxone (I) [42971-34-6] and 6-desoxy-6-methylenenaltrexone (II) [55096-26-9] had the greatest increase in potency over parent compounds Structure-activity relations were discussed. The experimental process involved the reaction of trimethyloxosulphonium chloride(cas: 5034-06-0).Application of 5034-06-0

The Article related to morphine antagonist noroxymorphone, naloxone analog morphine antagonist, naltrexone analog morphine antagonist, Pharmacodynamics: Structure-Activity and other aspects.Application of 5034-06-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 20, 2020, Liu, Jiaxin; Li, Quanzhe; Wei, Yin; Shi, Min published an article.Application In Synthesis of 2-Amino-4-chlorobenzoic acid The title of the article was Visible Light Induced Cyclization to Spirobi[indene] Skeletons from Functionalized Alkylidienecyclopropanes. And the article contained the following:

In this paper, we revealed a metal-free and visible light photoinduced method for the rapid construction of spirobi[indene] skeletons, e.g., I, providing a simple and efficient way for easy access to spirobi[indene] scaffolds under mild conditions along with a broad substrate scope and good functional group tolerance. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Application In Synthesis of 2-Amino-4-chlorobenzoic acid

The Article related to alkylidenecyclopropane nucleophile light cascade cyclization green, spiro indene preparation, Alicyclic Compounds: Spiro Compounds and other aspects.Application In Synthesis of 2-Amino-4-chlorobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Esteve-Turrillas, F. A.; Mercader, J. V.; Agullo, C.; Abad-Somovilla, A.; Abad-Fuentes, A. published an article in 2017, the title of the article was A class-selective immunoassay for simultaneous analysis of anilinopyrimidine fungicides using a rationally designed hapten.SDS of cas: 35444-44-1 And the article contains the following content:

The development of multianalyte immunoassays constitutes a main research issue in the field of bioanal. techniques. In the present study, class-specific antibodies against the three members of the anilinopyrimidine family of fungicides (pyrimethanil, cyprodinil and mepanipyrim) were raised by using a bioconjugate of a rationally designed hapten [5-(6-methyl-2-(phenylamino)pyrimidin-4-yl)pentanoic acid]. Highly sensitive immunoassays were developed for the generic determination of these compounds, using the competitive ELISA (ELISA). Particularly, a direct antibody-coated competitive ELISA afforded identical sensitivity for the three anilinopyrimidines, with IC50 values of 0.26, 0.27 and 0.25 μg L-1 for pyrimethanil, cyprodinil and mepanipyrim, resp. This immunoassay was fully characterized and applied to the multianalyte determination of anilinopyrimidine fungicides in white and red wines, with a limit of quantification of 1 μg L-1, average recoveries from 93.1 to 114.4%, and relative standard deviations lower than 20%. Com. wine samples were analyzed and those containing detectable anilinopyrimide residues were verified by a reference chromatog. technique. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).SDS of cas: 35444-44-1

The Article related to anilinopyrimidine fungicide immunoassay hapten, Food and Feed Chemistry: Analysis and other aspects.SDS of cas: 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 30, 2015, Esteve-Turrillas, Francesc A.; Mercader, Josep V.; Agullo, Consuelo; Abad-Somovilla, Antonio; Abad-Fuentes, Antonio published an article.Application of 35444-44-1 The title of the article was Moiety and linker site heterologies for highly sensitive immunoanalysis of cyprodinil in fermented alcoholic drinks. And the article contained the following:

Cyprodinil is a new-generation anilinopyrimidine fungicide widely used in crop protection and frequently found in fruits. In this study, novel derivatives of cyprodinil with linker site heterologies were synthesized and employed in order to produce antibodies with enhanced affinity. Moreover, moiety-heterologous haptens were designed and prepared for assay sensitivity improvement. Two competitive enzyme-linked immunosorbent assays for the anal. of this active substance were developed using direct and indirect formats, achieving IC50 values around 0.15 μg/L. Anal. figures of merit and usability of the optimized assays were evaluated with wine and cider as model food processed matrixes. The obtained recoveries were from 90% to 120%, and the limit of quantification was in the 1-5 μg/L range. Finally, a monitoring study (n = 150) was performed to estimate the occurrence and the concentration of cyprodinil in com. wine and cider products from different origins. We found that 28% of the analyzed wine samples contained cyprodinil residues at levels higher than 5 μg/L. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Application of 35444-44-1

The Article related to cyprodinil hapten antibody wine cider elisa, Food and Feed Chemistry: Analysis and other aspects.Application of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics