Chlorides-buliding-blocks

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 1878-65-5, formula is C8H7ClO2, Name is 3-Chlorophenylacetic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Safety of 3-Chlorophenylacetic acid.

Ji, Dong-Sheng;Liang, Hui;Yang, Kai-Xuan;Feng, Zhi-Tao;Luo, Yong-Chun;Xu, Guo-Qiang;Gu, Yucheng;Xu, Peng-Fei research published ã€?Solvent directed chemically divergent synthesis of β-lactams and α-amino acid derivatives with chiral isothioureaã€? the research content is summarized as follows. A protocol for the chem. divergent synthesis of β-lactams I (R¹ = Ph, 3-ClC₆H₄, 2-thienyl, etc.; R² = Ph, 1-naphthyl, 3-thienyl, 3-indolyl, etc.; R³ = Me, Et, PhCH₂) and α-amino esters II with isothiourea catalysis by switching solvents has been developed. The stereospecific Mannich reaction occurring between imines III and zwitterionic enolate intermediates, generated from the catalyst and perfluorophenyl esters IV, followed by intramol. lactamization afforded β-lactams I when dichloromethane and acetonitrile were used as solvents. However, when EtOH was used as the solvent, the intermediates underwent an intermol. esterification reaction, and α-amino acid derivatives II were produced. Detailed mechanistic experiments were conducted to prove that these two kinds of products came from the same intermediates. Furthermore, chem. diversified transformations of β-lactam and α-amino acid derivatives were achieved.

Safety of 3-Chlorophenylacetic acid, 3-Chlorophenylacetic acid is a useful research compound. Its molecular formula is C8H7ClO2 and its molecular weight is 170.59 g/mol. The purity is usually 95%.
3-Chlorophenyl acetic acid is a compound that has resonance mass of 269. The compound reacts with HBr and water to produce 3-chlorobenzene, carbon dioxide and hydrogen chloride. A reaction product of this chemical is covid-19 pandemic (a type of drug)., 1878-65-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Reference of 6334-18-5.

Jaiswal, Shivani;Akhilesh;Uniyal, Ankit;Tiwari, Vinod;Raja Ayyannan, Senthil research published ã€?Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazonesã€? the research content is summarized as follows. We designed and synthesized a series of 4-methylsulfonylphenyl semicarbazones I [R¹ = H, Me, Ph; R² = H, 2-OH, 4-F, etc.] and II [R¹ = H, allyl, propargyl; R² = H, Cl] and evaluated for fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) inhibition properties. Most of the compounds showed potency toward both enzymes with leading FAAH selectivity. Compound (Z)-2-(2,6-dichlorobenzylidene)-N-(4-(methylsulfonyl)phenyl)hydrazine-1-carboxamide emerged as the lead inhibitor against both FAAH (IC₅₀ = 11 nM) and MAGL (IC₅₀ = 36 nM). The lead inhibitor inhibited FAAH by non-competitive mode, but showed a mixed-type inhibition against MAGL. Mol. docking study unveiled that the docked ligands bind favorably to the active sites of FAAH and MAGL. The lead inhibitor interacted with FAAH and MAGL via π-π stacking via Ph ring and hydrogen bonding through sulfonyl oxygen atoms or amide NH. Moreover, the stability of docked complexes was rationalized by mol. simulation studies. PAMPA assay revealed that the lead compound was suitable for blood-brain penetration. The lead compound showed better cell viability in lipopolysaccharide-induced neurotoxicity assay in SH-SY5Y cell lines. Further, in-vivo experiments unveiled that dual inhibitor was safe up to 2000 mg/kg with no hepatotoxicity. The dual FAAH-MAGL inhibitor produced significant anti-nociceptive effect in the CCI model of neuropathic pain without altering locomotion activity. Lastly, the lead compound exhibited promising ex-vivo FAAH/MAGL inhibition activity at the dose of 10 mg/kg and 20 mg/kg. Thus, these findings suggest that the semicarbazone-based lead compound can be a potential template for the development of agents for neuropathic pain.

6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Reference of 6334-18-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Formula: C16H24Cl2Ir2.

Jacko, Jaroslav;Stas, Monika;Rulisek, Lubomir;Cisarova, Ivana;Kotora, Martin research published �Ir-Catalyzed Cycloaddition of Tribenzocyclyne with Biphenylenes� the research content is summarized as follows. Ir-catalyzed C-C bond activation in biphenylenes followed by a reaction with tribenzocyclyne was demonstrated as a suitable method for synthesizing strained and unknown monoadducts with the tetradehydrotetrabenzo[a,c,e,i]cyclododecene scaffold ([12]annulenes). Modification of reaction conditions also furnished [12]annulene products with cis and/or trans double bonds formed by hydrogen transfer. The [9]annulene side product was formed upon the reaction of the benzyl radical with tribenzocyclyne during the Bergman cyclization. All isolated compounds were fully characterized by HRMS, NMR and X-ray diffraction anal.

Formula: C16H24Cl2Ir2, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Reference of 3900-89-8.

Ito, Sora;Fujimoto, Hayato;Tobisu, Mamoru research published �Non-stabilized Vinyl Anion Equivalents from Styrenes by N-Heterocyclic Carbene Catalysis and Its Use in Catalytic Nucleophilic Aromatic Substitution� the research content is summarized as follows. A protocol for the catalytic nucleophilic activation of unactivated styrenes was reported, which enables the generation of a non-stabilized alkenyl anion equivalent as a transient intermediate. In the reaction, N-heterocyclic carbenes add across styrenes to generate ylide intermediates, which could then be used in intramol. nucleophilic aromatic substitution reactions of aryl fluorides, chlorides and Me ethers. The method allowed for straightforward access to complex polyaromatic compounds

Reference of 3900-89-8, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. SDS of cas: 12112-67-3.

Ilyin, I. Yu.;Mirzaeva, I. V.;Sukhikh, T. S.;Bonegardt, D. V.;Basova, T. V. research published ã€?STUDY OF THE CORRELATION BETWEEN THE STRUCTURE OF THE [Ir(cod)Cp] COMPLEX AND ITS THERMAL PROPERTIESã€? the research content is summarized as follows. A volatile iridium(I) complex [Ir(cod)Cp] (cod – 1,5-cyclooctadiene, Cp – cyclopentadienyl) is synthesized and characterized by IR and NMR spectroscopy. The structure of [Ir(cod)Cp] is determined by single crystal X-ray diffraction. The anal. of the Hirshfeld surface along with the electron d. distribution and its topol. based on the AIM theory reveals the presence of many intermol. contacts, with C(Cp)···H(Cp), Ir···H(Cp), H(cod)···H(cod) being the strongest. The presence of these contacts in the crystal structure of the compound leads to higher m.ps. and transition temperatures to the gas phase, as compared to those of a similar complex containing methyl-substituted cyclopentadienyl. Lattice energy calculations and results of the thermogravimetric anal. of the [Ir(cod)Cp] complex are well consistent with the similar data for β-diketonate complexes [Ir(cod)L], which suggests that there may be a correlation between lattice energies and melting and a 50% weight loss temperatures

SDS of cas: 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. COA of Formula: C7H8ClN.

Iakovenko, Roman O.;Chrenko, Daniel;Kristek, Jozef;Desmedt, Eline;Zalesak, Frantisek;De Vleeschouwer, Freija;Pospisil, Jiri research published ã€?Heteroaryl sulfonamide synthesis: Scope and limitationsã€? the research content is summarized as follows. Heteroaryl sulfonamides are important structural motifs in the medicinal and agrochem. industries. However, their synthesis often relies on the use of heteroaryl sulfonyl chlorides, which are unstable and toxic reagents. Herein, the authors report a protocol that allows direct oxidative coupling of heteroaryl thiols R¹SH (R¹ = pyrimidin-2-yl, pyridin-2-yl, 1,3-benzothiazol-2-yl, etc.) to primary amines R²NH₂ (R² = CH₂Ph, CH(Me)CO₂Me, CH(CO₂Me)(CH₂)₂CO₂Me, etc.) and Me (2S)-pyrrolidine-2-carboxylate, readily available and inexpensive commodity chems. The transformation proceeds under mild reaction conditions and yields the desired N-alkylated sulfonamides, e.g., I, in good yields. N-alkyl heteroaryl sulfonamides can be further transformed using a microwave-promoted Fukuyama-Mitsunobu reaction to give N,N-dialkyl heteroaryl sulfonamides. The developed protocols thus enable the preparation of previously difficult to prepare sulfonamides (toxic reagents, harsh conditions, and low yields) under mild conditions.

COA of Formula: C7H8ClN, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Electric Literature of 349-88-2.

Huo, Yong-Wang;Qi, Xinxin;Wu, Xiao-Feng research published ã€?Nickel-Catalyzed Carbonylative Synthesis of α,β-Unsaturated Thioesters from Vinyl Triflates and Arylsulfonyl Chloridesã€? the research content is summarized as follows. A straightforward and efficient synthesis of α,β-unsaturated thioesters RC(O)SR¹ [R = cyclopenten-1-yl, cyclohexen-1-yl, 3,4-dihydronaphthalen-1-yl, etc.; R¹ = 4-MeC₆H₄, 4-FC₆H₄, 4-MeOC₆H₄, etc.] had been developed via a nickel-catalyzed thiocarbonylation reaction of vinyl triflates with arylsulfonyl chlorides. With Mo(CO)₆ as both CO source and reductant, a variety of α,β-unsaturated thioesters were obtained in moderate to good yields with very good functional group compatibility. It was noteworthy that the present method was the first example on nickel-catalyzed carbonylative synthesis of α,β-unsaturated thioesters by using arylsulfonyl chlorides as the coupling partner.

Electric Literature of 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 3900-89-8, formula is C6H6BClO2, Name is (2-Chlorophenyl)boronic acid. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. COA of Formula: C6H6BClO2.

Huang, Zhigang;Luo, Wei;Xu, Deming;Guo, Fengxun;Yang, Meng;Zhu, Yusong;Shen, Liang;Chen, Shuhui;Tang, Dongdong;Li, Lei;Li, Yongguo;Wang, Bin;Franzblau, Scott G.;Ding, Charles Z. research published �Discovery and preclinical profile of sudapyridine (WX-081), a novel anti-tuberculosis agent� the research content is summarized as follows. Multidrug resistant tuberculosis (MDR-TB) remains a major human health challenge. Bedaquiline was approved in 2012 by the US FDA, and listed by WHO as a treatment for multidrug-resistant tuberculosis (MDR-TB) in 2018. However, the side effects of bedaquiline including the risk of unexplained mortality, QTc prolongation and hepatotoxicity limit its wide clin. use. Based on bedaquiline, we describe herein discovery and development of a novel diarylpyridine series, which led to identification of WX-081 (sudapyridine, 21l). It displayed excellent anti-mycobacterial activity against M. tuberculosis H37Rv in vitro and in vivo and low cytotoxicity; addnl. WX-081 had excellent pharmacokinetic parameters in animals, better lung exposure and lower QTc prolongation potential compared to bedaquiline. WX-081 is currently under clin. phase II development (NCT04608955).

COA of Formula: C6H6BClO2, 2-Chlorophenylboronic acid is a useful research compound. Its molecular formula is C6H6BClO2 and its molecular weight is 156.38 g/mol. The purity is usually 95%.
2-Chlorophenylboronic acid used in the preparation of imidazo[1,2-a]pyridine amides which has tuberculostatic activity.
2-Chlorophenylboronic acid is a diphenyl ether that can be used as a building block for the synthesis of benzodiazepine receptor ligands. It has been shown to be an efficient nucleophile, leading to the formation of carbonyl groups in the presence of halides. 2-Chlorophenylboronic acid has also been shown to inhibit p38 kinase activity and may be useful for anticancer therapy., 3900-89-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Related Products of 104-86-9.

Huang, Yan;Shen, Yinjing;Li, Sichen;Zheng, Ruijie;Zhang, Chengjian;Li, Benxia;Zhang, Kun research published ã€?Dual-emission samarium macrocycle as a lab-on-a-molecule enables high-throughput discrimination of anionic sulfonate surfactantsã€? the research content is summarized as follows. Nowadays, it is still a huge challenge to efficiently discriminate of analogus anionic sulfonate surfactants, which are noxious xenobiotics related to many safety concerns of environment and life. Recently, great advances in orthogonal detection have shown the great advantages of principal component anal. (PCA) to construct a comprehensive statistical method for sensing signals in recognizing more analytes with similar structures. Inspired by sensor arrays, we propose a new ′one-element-two-channelâ€?protocol upon a dual-emission samarium macrocycle Sm-2o as the lab-on-a-mol., containing two isolated emissions of macrocycle (443 nm) and Sm(III) (643 nm) emitters as two fluorescence channels. Herein, these targeted surfactants instruct original fluorescences of Sm-2o to generate diverse sensing signals which can finally convert into unique fingerprint patterns and distinguish four anionic surfactants (SDS, SDSO, SCI and AOS) from other ten ones, even their proportional concentrations Significantly, this high-throughput discrimination is realized by different receptor-analyte interactions and the structure transformation of Sm-2o in diverse microenvironments formed in various types of surfactants. Furthermore, these sensing systems also show satisfactory discrimination and semiquantitation performances for mixtures of anionic surfactants, especially the SDS and SDBS, in real water sample, revealing the practicability of our lab-on-a-mol. probe. On the basis of the PCA method, this work provides a vital reference for the design and application of multianalyte chemosensors.

Related Products of 104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Name: 3-Bromobenzenesulfonyl chloride.

Huang, Huan-Ming;Bellotti, Peter;Erchinger, Johannes E.;Paulisch, Tiffany O.;Glorius, Frank research published ã€?Radical Carbonyl Umpolung Arylation via Dual Catalysisã€? the research content is summarized as follows. A series of aryl benzoates I [R = iPr, tBu, cyclohexyl, etc.; R¹ = 4-NCC₆H₄, 2-NCC₆H₄, 2-pyridyl, etc.] via dual nickel and photoredox catalyzed radical carbonyl umpolung arylation of aldehydes and aryl bromides was reported. This redox-neutral approach provided a complementary method to construct Grignard-type products from (hetero)aryl bromides and aliphatic aldehydes, without the need for prefunctionalization. Sequential activation, hydrogen atom transfer and halogen atom transfer process could directly converted aldehydes to the corresponding ketyl radicals, which further react with aryl-nickel intermediates in an overall polarity-reversal process. This radical strategy tolerated-among others-acidic functional groups, heteroaryl motifs and sterically hindered substrates and was applied in the late-stage modification of drugs and natural products.

Name: 3-Bromobenzenesulfonyl chloride, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1�benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics