Chlorides-buliding-blocks

Li, Yangyang published the artcileModular access to substituted cyclohexanes with kinetic stereocontrol, HPLC of Formula: 939-99-1, the publication is Science (Washington, DC, United States) (2022), 376(6594), 749-753, database is CAplus and MEDLINE.

Substituted six-membered cyclic hydrocarbons are common constituents of biol. active compounds Although methods for the synthesis of thermodynamically favored, disubstituted cyclohexanes are well established, a reliable and modular protocol for the synthesis of their stereoisomers is still elusive. Herein, the authors report a general strategy for the modular synthesis of disubstituted cyclohexanes with excellent kinetic stereocontrol from readily accessible substituted methylenecyclohexanes by the implementation of chain-walking catalysis. Mechanistically, the initial introduction of a sterically demanding B ester group adjacent to the cyclohexane is key to guiding the stereochem. outcome. The synthetic potential of this methodol. was highlighted in late-stage modification of complex bioactive mols. and in comparison with current cross-coupling techniques.

Science (Washington, DC, United States) published new progress about 939-99-1. 939-99-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Benzyl chloride,Benzene, name is 1-(Chloromethyl)-4-(trifluoromethyl)benzene, and the molecular formula is C8H6ClF3, HPLC of Formula: 939-99-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yang, Dongsheng published the artcileDelivery of siRNA using cationic liposomes incorporating stearic acid-modified octa-arginine, SDS of cas: 42074-68-0, the publication is Anticancer Research (2016), 36(7), 3271-3276, database is CAplus and MEDLINE.

Cationic liposomes incorporating stearic acid-modified octa-arginine (StA-R8) were evaluated for survivin small interfering RNA (siRNA) delivery. StA-R8 was synthesized and incorporated into liposomes. The composition of liposomes was optimized. Physicochem. properties, cytotoxicity, cellular uptake and gene silencing activity of the liposomes complexed to survivin siRNA were investigated. The results showed that StA-R8-containing liposomes had reduced cytotoxicity and improved delivery efficiency of siRNA into cancer cells compared with StA-R8 by itself.

Anticancer Research published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C8H12BNO4S, SDS of cas: 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Yun published the artcileSynthesis of a phenylboronic acid-functionalized thermosensitive block copolymer and its application in separation and purification of vicinal-diol-containing compounds, Quality Control of 332154-58-2, the publication is RSC Advances (2016), 6(85), 82309-82320, database is CAplus.

A phenylboronic acid-functionalized amphiphilic thermosensitive block copolymer was prepared by taking PEO₂₀PPO₆₀PEO₂₀ as the template and a detailed study of its performance in downstream separation processes was presented. Alizarin red was used as the model compound to study the feasibility of using an affinity adsorption system and aqueous two-phase flotation system based on the phenylboronic acid-functionalized PEO₂₀PPO₆₀PEO₂₀ for the separation and purification of ortho-hydroxyl compounds The optimized conditions of the affinity adsorption experiment were: 2% phenylboronic acid-functionalized PEO₂₀PPO₆₀PEO₂₀, 0.3 mg alizarin red, 40% K₂HPO₄ and 4 h adsorption time. The affinity adsorption rate of alizarin red reached 98% under such conditions. In addition, a flotation recovery of alizarin red of 97% was obtained under the optimal conditions of aqueous two-phase flotation: 0.3 g of collector, 12 g K₂HPO₄, 0.6 mg alizarin red, 15 mL min^-1 nitrogen flow rate and 40 min flotation time. Both methods are capable of separating alizarin red, suggesting their broad application prospect in downstream separation engineering of vicinal-diol-containing compounds

RSC Advances published new progress about 332154-58-2. 332154-58-2 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,acyl chloride,Boronic Acids,Boronic Acids,Boronic acid and ester,, name is (3-(Chlorocarbonyl)phenyl)boronic acid, and the molecular formula is C8H11NO, Quality Control of 332154-58-2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shao, Dongyun published the artcilePreparation of polycarboxylic acid-functionalized silica supported Pt catalysts and their applications in alkene hydrosilylation, HPLC of Formula: 14799-94-1, the publication is RSC Advances (2018), 8(36), 20379-20393, database is CAplus and MEDLINE.

A series of novel immobilized platinum catalysts was prepared by loading Pt onto silica particles modified with polycarboxylic acid groups such as diethylenetriaminepentaacetic acid (DTPA), nitrilotriacetic acid (NTA) and succinic acid (SA). The three modified heterogeneous Pt catalysts were characterized using IR spectroscopy (IR), transmission electron microscopy (TEM), XPS, energy dispersive X-ray spectroscopy (EDS) and at. absorption spectroscopy (AAS). The residual H₂PtCl₆ solutions were characterized using UV spectroscopy (UV). The polycarboxylic acid-functionalized silica supported Pt catalysts were used to catalyze alkene hydrosilylation and 1-hexene was chosen as a model alkene. The data indicated that the catalytic performance was strongly dependent on the properties of the polycarboxylic acid group bonded to the silica particles. Among them, DTPA-functionalized silica supported Pt (SiO₂-DTPA-Pt) showed the best catalytic activity and reusability. Furthermore, some hydrosilylation reactions between other linear alkenes (1-heptene, 1-octene, 1-decene, 1-do-decene, 1-tetra-decene, 1-hexa-decene, 1-octa-decene, styrene or cis-hex-2-ene), or ring type alkenes (norbornene) with methyldichlorosilane could be catalyzed in the presence of these three Pt catalysts. Their high activities were more than 90%, and their selectivities were more than 99%, which were apparently better than homogeneous Pt catalysts. In addition, reactions with cyclohexene were also successfully catalyzed by the Pt catalysts. These results indicate that the polycarboxylic acid-functionalized silica gel supported Pt catalysts have potential value in industrial hydrosilylation reactions.

RSC Advances published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C16H20N2, HPLC of Formula: 14799-94-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shao, Dongyun published the artcilePreparation of polycarboxylic acid-functionalized silica supported Pt catalysts and their applications in alkene hydrosilylation, Recommanded Product: Dichloro(methyl)(octyl)silane, the publication is RSC Advances (2018), 8(36), 20379-20393, database is CAplus and MEDLINE.

A series of novel immobilized platinum catalysts was prepared by loading Pt onto silica particles modified with polycarboxylic acid groups such as diethylenetriaminepentaacetic acid (DTPA), nitrilotriacetic acid (NTA) and succinic acid (SA). The three modified heterogeneous Pt catalysts were characterized using IR spectroscopy (IR), transmission electron microscopy (TEM), XPS, energy dispersive X-ray spectroscopy (EDS) and at. absorption spectroscopy (AAS). The residual H₂PtCl₆ solutions were characterized using UV spectroscopy (UV). The polycarboxylic acid-functionalized silica supported Pt catalysts were used to catalyze alkene hydrosilylation and 1-hexene was chosen as a model alkene. The data indicated that the catalytic performance was strongly dependent on the properties of the polycarboxylic acid group bonded to the silica particles. Among them, DTPA-functionalized silica supported Pt (SiO₂-DTPA-Pt) showed the best catalytic activity and reusability. Furthermore, some hydrosilylation reactions between other linear alkenes (1-heptene, 1-octene, 1-decene, 1-do-decene, 1-tetra-decene, 1-hexa-decene, 1-octa-decene, styrene or cis-hex-2-ene), or ring type alkenes (norbornene) with methyldichlorosilane could be catalyzed in the presence of these three Pt catalysts. Their high activities were more than 90%, and their selectivities were more than 99%, which were apparently better than homogeneous Pt catalysts. In addition, reactions with cyclohexene were also successfully catalyzed by the Pt catalysts. These results indicate that the polycarboxylic acid-functionalized silica gel supported Pt catalysts have potential value in industrial hydrosilylation reactions.

RSC Advances published new progress about 14799-93-0. 14799-93-0 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(methyl)(octyl)silane, and the molecular formula is C16H20N2, Recommanded Product: Dichloro(methyl)(octyl)silane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Laiming published the artcilePreparation and evaluation of a novel and high efficient boronic acid-substituted silica supported Pt catalyst, Safety of Dichloro(hexyl)(methyl)silane, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2019), 322-330, database is CAplus.

A smart design of transition metal nanocatalyst can efficiently improve its catalytic activity and use value. In this work, platinum (Pt) was successfully anchored to silica gel with phenylboronic acid group first time and formed nanoparticles (0.5-5 nm) which afforded a highly active supported catalyst for the hydrosilylation of olefins. The turnover number and regioselectivity in the reaction of methyldichlorosilane and 1-octene using 0.00000004 mol of the immobilized Pt catalyst approached 1,321,317 and 99% over 12 h. The corresponding hydrosilylation products in excellent yields and regioselectivities were obtained when we employed a broad range of terminal aliphatic olefins and methyldichlorosilane as substrates. The fully immobilized Pt nanoparticles could be recycled at least 10 runs without any obvious loss in catalytic activity.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C7H16Cl2Si, Safety of Dichloro(hexyl)(methyl)silane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Laiming published the artcilePreparation, characterization and evaluation of a series of heterogeneous platinum catalysts immobilized on magnetic silica with different acid ligands, Application In Synthesis of 14799-94-1, the publication is Transition Metal Chemistry (Dordrecht, Netherlands) (2019), 44(8), 779-787, database is CAplus.

Platinum was immobilized on magnetic silica gel by means of boronic, nitric, carboxylic or sulfuric acid ligands to give four heterogeneous Pt nano-catalysts, designated as Fe₃O₄@SiO₂-BA@Pt, Fe₃O₄@SiO₂-NA@Pt, Fe₃O₄@SiO₂-CA@Pt and Fe₃O₄@SiO₂-SA@Pt, resp. Particles of these mono-dispersible Pt catalysts were 10-20 nm in size and could be separated for recycling by means of a magnet. Fe₃O₄@SiO₂-BA@Pt (0.174 mmol/g Pt) showed the best catalytic activity and selectivity, which were better than Speier’s catalyst. Its turnover numbers were up to 1.7 X 10⁶ and 1.1 X 10⁶ for hydrosilylation of 1-hexene or styrene, resp. This material could also catalyze the hydrosilylation of a broad range of alkenes and alkynes as substrates and methyldichlorosilane or triethoxysilane as silanes. Similar yields of 1-hexyl-methyldichlorosilane at the first and eighth runs (96.5% and 95.2%, resp.), together with a final Pt content of 0.171 mmol/g indicated the outstanding stability of Fe₃O₄@SiO₂-BA@Pt under the catalytic reaction conditions.

Transition Metal Chemistry (Dordrecht, Netherlands) published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C7H16Cl2Si, Application In Synthesis of 14799-94-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Laiming published the artcilePreparation and evaluation of a novel and high efficient boronic acid-substituted silica supported Pt catalyst, Formula: C9H20Cl2Si, the publication is Colloids and Surfaces, A: Physicochemical and Engineering Aspects (2019), 322-330, database is CAplus.

A smart design of transition metal nanocatalyst can efficiently improve its catalytic activity and use value. In this work, platinum (Pt) was successfully anchored to silica gel with phenylboronic acid group first time and formed nanoparticles (0.5-5 nm) which afforded a highly active supported catalyst for the hydrosilylation of olefins. The turnover number and regioselectivity in the reaction of methyldichlorosilane and 1-octene using 0.00000004 mol of the immobilized Pt catalyst approached 1,321,317 and 99% over 12 h. The corresponding hydrosilylation products in excellent yields and regioselectivities were obtained when we employed a broad range of terminal aliphatic olefins and methyldichlorosilane as substrates. The fully immobilized Pt nanoparticles could be recycled at least 10 runs without any obvious loss in catalytic activity.

Colloids and Surfaces, A: Physicochemical and Engineering Aspects published new progress about 14799-93-0. 14799-93-0 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(methyl)(octyl)silane, and the molecular formula is C9H20Cl2Si, Formula: C9H20Cl2Si.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Futing published the artcilePreparation of efficient and environment-friendly silica-supported EDTA platinum catalyst and its applications in hydrosilylation of olefins and methyldichlorosilane, HPLC of Formula: 14799-94-1, the publication is Journal of Molecular Catalysis A: Chemical (2016), 254-263, database is CAplus.

A novel catalyst by preparing silica supported EDTA (EDTA) platinum complex was developed. The preparation conditions, such as heating temperature and solvent types, were optimized. The catalyst was phosphine-free and sulfur-free which was characterized by IR spectroscopy (IR), energy dispersive X-ray spectrometer (EDS), transmission electron microscopy (TEM), high resolution transmission electron microscopy (HRTEM), XPS, UV spectroscopy (UV) and at. absorption spectroscopy (AAS). Its catalytic activity was evaluated by catalyzing solventless hydrosilylation reactions. In the hydrosilylation reaction between 1-hexene and methyldichlorosilane, the new catalyst showed a higher catalytic activity than that provided by Speier’s catalyst. Moreover, the new catalyst could be reused for 12 times without obvious loss of catalytic activity. To confirm its practical feasibility, catalyzing the hydrosilylation reaction between 1-octene and methyldichlorosilane was performed. Our results indicated that the new catalyst can efficiently catalyze the hydrosilylation reaction.

Journal of Molecular Catalysis A: Chemical published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C7H16Cl2Si, HPLC of Formula: 14799-94-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yin, Xue-Song published the artcileCopper(II)-catalyzed methoxylation of unactivated (hetero)aryl C-H bonds using a removable bidentate auxiliary, Related Products of chlorides-buliding-blocks, the publication is Organic Chemistry Frontiers (2015), 2(2), 119-123, database is CAplus.

A copper(II)-catalyzed methoxylation of unactivated (hetero)aryl C-H bonds directed by newly developed PIP directing group with methanol has been achieved. This protocol occurs efficiently with a catalytic amount of copper (5 mol%), is a simple and environmentally benign reaction system, has a broad substrate scope and high functional group tolerance.

Organic Chemistry Frontiers published new progress about 6313-54-8. 6313-54-8 belongs to chlorides-buliding-blocks, auxiliary class Pyridine,Chloride,Carboxylic acid, name is 2-Chloroisonicotinic acid, and the molecular formula is C24H20Ge, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics