Author: Jessica.F

Furuya, Takeru; Kaiser, Hanns Martin; Ritter, Tobias published an article in 2008, the title of the article was Palladium-mediated fluorination of arylboronic acids.Name: 4-Chloro-2-fluorotoluene And the article contains the following content:

Novel palladium complexes allow mild, two-step fluorination of aryl boronic acids. The reaction is regiospecific, functional-group tolerant, has a broad substrate scope, and is ideally suited for the introduction of fluorine substituents at a late stage for aryl fluoride synthesis. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Name: 4-Chloro-2-fluorotoluene

The Article related to aryl boronic acid palladium acetate complex transmetallation, complex aryl palladium preparation electrophilic fluorination, regioselective aryl fluoride preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Name: 4-Chloro-2-fluorotoluene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 1, 2012, Wang, Kai; Song, Lvhua; Chen, Yunfeng; Yu, Faquan; Chi, Ruan; Huang, Ting published a patent.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Synthesis of janus green B. And the patent contained the following:

The method comprises dissolving 4-amino-N,N-diethyl aniline in an aqueous acid , mixing with aniline at molar ratio of 1: 1-2 in the presence of inorganic oxidants (chromate, permanganate, or peroxo acid salt), stirring at pH 4-7, -5 to 50°C for 0.5-5 h, reacting with 1-2 M fold aniline, reacting at 0-100°C for 1-10 h, filtering, vacuum concentrating, precipitating, filtering, drying cake to obtain methylene purple 3RAX, adding into acid water at -5°C, slowly dripping sodium nitrite aqueous solution, reacting at -5 to 25°C for 1-5 h, reacting with 1-2 M fold N,N-didimethylaniline for 1-10 h, vacuum distilling, dispersing residue in saturated saline, filtering, and drying cake. This invention has easy-obtained raw materials, simple process, and certain industrialization value. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to janus green b dye synthesis, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 1, 2012, Wang, Kai; Jin, Qi; Yu, Faquan; Zhang, Heng; Chi, Ruan; Huang, Ting; Zhang, Xiulan; Wan, Chunjie published a patent.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Process for synthesizing janus green b. And the patent contained the following:

The process comprises the following steps: dissolving p-phenylenediamine and N,N-diethylbenzene in acid water, controlling pH of 4-7 in the presence of inorganic oxidant, reacting at (-5)-50 °C, stirring for 0.5-5 h, then adding aniline, increasing temperature to 0-100 °C, reacting for 1-10 h, filtering, concentrating, salting out, filtering, drying filter cake, obtaining methylene violet 3RAX, adding said methylene violet 3RAX into acid water, slowly dripping sodium nitrite aqueous solution, reacting at (-5)-25 °C for 1-5 h, adding N,N-dimethylaniline, reacting for 1-10 h, reducing pressure to dryness, dispersing residue in saturated saline, filtering, and drying filter cake. This process has the advantages of easily obtained raw materials and simple procedures. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to synthesis janus green b oxidation, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 18, 2015, Zhou, Xin; Yu, Changjiang; Feng, Zeya; Yu, Yang; Wang, Jun; Hao, Erhong; Wei, Yun; Mu, Xiaolong; Jiao, Lijuan published an article.Name: Methyl 6-chloro-6-oxohexanoate The title of the article was Highly Regioselective α-Chlorination of the BODIPY Chromophore with Copper(II) Chloride. And the article contained the following:

A general and efficient method for α-chlorination of 4,4′-difluoro-4-bora-3a,4a-diaza-s-indacenes (BODIPYs) was developed using CuCl2 as chlorination reagent. The reaction is characterized by complete 3/5-positions of BODIPY regioselectivity. This unusual highly regioselective α-halogenation of BODIPY is in sharp contrast to previously reported halogenation methods which preferred to occur first at the 2,6-positions of BODIPY. This approach provides a straightforward, facile, and economical route to 3- and/or 5-chloroBODIPYs with various meso-groups (H, alkyl, and aryl) and their derivatives The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Name: Methyl 6-chloro-6-oxohexanoate

The Article related to regioselective chlorination bodipy copper chloride, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Name: Methyl 6-chloro-6-oxohexanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On July 31, 2003, Jonnalagadda, S. B.; Shezi, M.; Pare, B. published an article.Synthetic Route of 4569-86-2 The title of the article was Uncatalyzed and ruthenium(III)-catalyzed reaction of acidic chlorite with methylene violet. And the article contained the following:

The kinetics and mechanism of the uncatalyzed and Ru(III)-catalyzed oxidation of methylene violet [3-amino-7-(diethylamino)-5-phenylphenazinium chloride] (MV) by acidic chlorite is reported. With excess concentrations of other reactants, both uncatalyzed and catalyzed reactions had pseudo-first-order kinetics with respect to MV. The uncatalyzed reaction had first-order dependence on chlorite and H+ concentrations, but the catalyzed reaction had first-order dependence on both chlorite and catalyst, and a fractional order with respect to [H+]. The rate coefficient of the uncatalyzed reaction is (5.72 ± 0.19) M-2 s-1, while the catalytic constant for the catalyzed reaction is (22.4 ± 0.3) × 103 M-1 s-1. Stoichiometry is dependent on the initial concentration of chlorite present. Consistent with the exptl. results, pertinent mechanisms are proposed. The proposed 15-step mechanism is simulated using literature; exptl. and estimated rate coefficients and the simulated plots agreed well with the exptl. curves. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Synthetic Route of 4569-86-2

The Article related to chlorite oxidation kinetics methylene violet dye ruthenium catalyst, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Synthetic Route of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhang, Min; Hao, Erhong; Xu, Yajun; Zhang, Shengzhou; Zhu, Hongnian; Wang, Qi; Yu, Changjiang; Jiao, Lijuan published an article in 2012, the title of the article was One-pot efficient synthesis of pyrrolylBODIPY dyes from pyrrole and acyl chloride.Quality Control of Methyl 6-chloro-6-oxohexanoate And the article contains the following content:

A facile one-pot synthesis of pyrrolylBODIPY dyes from acid chloride and excess pyrrole was developed through oxidative nucleophilic substitution of in situ formed dipyrromethene with pyrrole. Fluorescence imaging of living cells by using selected dyes was successfully demonstrated. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Quality Control of Methyl 6-chloro-6-oxohexanoate

The Article related to pyrrolylbodipy dye pyrrole acyl chloride synthesis fluorescent imaging, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Quality Control of Methyl 6-chloro-6-oxohexanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 28, 1998, Proevska, L. I.; Pojarlieff, I. G. published an article.Computed Properties of 4569-86-2 The title of the article was 1H NMR spectra and structure of safranines. Hindered rotation of the 3-dialkylamino group in 7-azo derivatives. And the article contained the following:

The 1H NMR spectra of safranine derivatives are reported. Semiempirical calculations indicate that the high shielding of the 4- and 6-proton adjacent to an amino or hydroxyl group (resonating between 5.5 and 6.0 ppm) is due to accumulation of neg. charge on the 4-and 6-C atoms, augmented by the magnetic anisotropy effect of the orthogonal 5-Ph ring. The ortho protons of the latter resonate up field to the meta and para protons. Hindered rotation of dialkylamino groups, altogether unexpected in view of the rather low barriers in similar anilines, is observed only in the azo derivatives AM1 suggests that this is due to destabilization of the transition state when an amino group is substituted for an azo group. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Computed Properties of 4569-86-2

The Article related to azo derivative safranine hindered rotation, alkylamino hindered rotation safranine derivative, Dyes, Organic Pigments, Fluorescent Brighteners, and Photographic Sensitizers: Heterocyclics and other aspects.Computed Properties of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 12, 2022, Wang, Tao; Chen, Xuling; Li, Pengfei published an article.Computed Properties of 89-77-0 The title of the article was One-Pot Divergent Synthesis of Benzoxazines and Dihydroquinolines from Morita-Baylis-Hillman Alcohols. And the article contained the following:

Benzoxazines and hydroquinolines was prepared by a one-pot process via catalyst-controlled divergent annulations of Morita-Baylis-Hillman (MBH) alcs. In the presence of diazabicyclo[2.2.2]octane, MBH alcs. reacted with Boc2O to form MBH carbonates, followed by intramol. annulation to give 4H-benzo[d][1,3]oxazines. Divergently, the combination of Bu4NBr and NaOH enabled the formation of 1,2-dihydroquinolines from the same starting materials. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Computed Properties of 89-77-0

The Article related to hydroxy carboxypropylene benzamide intramol heterocyclization, carboxyethylene benzoxazine preparation, acyl dihydroquinoline carboxylate preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 6-Membered Rings, Two Hetero Atoms and other aspects.Computed Properties of 89-77-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On June 15, 2011, Sukchol, Kulthida; Thongyai, Supakanok; Praserthdam, Piyasan published an article.HPLC of Formula: 14602-86-9 The title of the article was Preparation and characterization of novel polyimide with chiral side chain for twist nematic liquid crystal display. And the article contained the following:

The synthesis of novel polyimide (PI) films containing chirals in side chain was investigated for utilizing in twist nematic (TN) liquid crystal display (LCD). The polyimide with amine side groups (PI4 a.m.) was prepared by two steps copolymerization of 4,4′-hexafluoroisopropylidene diphthalic anhydride (6FDA), 4,4′-oxydianiline (ODA), and 3,3′-diaminobezidine (4AM) in N-methyl-2- pyrrolidinone (NMP). In the first step, the oligomer of 6FDA-ODA with mole ratio 4:3 was synthesized. In the second step, the oligomer was reacted with 4AM by gradually dropping the oligomer into 4AM solution with the mole ratio 4:5 to obtain amino groups containing polyimide P14AM. By reacting chiral compounds, mandelic acid, menthyl chloroformate, and menthyl glyoxylate hydrate using condensation reaction with amine groups along polyimide mols., the novel polyimides can be synthesized. Their chem. structures were confirmed by Fourier transform IR spectroscopy and NMR spectroscopy (1H-NMR). The coated glass slides pairs were coated with PI4AM and with each polyimide/chiral. The liquid crystals (LCs) were inserted between two coated glass slides at above the nematic temperature under the polarized light microscope to observe the alignment of LCs. The results showed the alignment of LCs in some certain direction under polyimide/chiral pair, regardless of the type of the chiral mol. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).HPLC of Formula: 14602-86-9

The Article related to polyimide chiral side chain alignment liquid crystal display, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Other and other aspects.HPLC of Formula: 14602-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 12, 2021, Wang, Kai; Jia, Fang; Song, Shihao; Zhao, Fang; Pan, Jie; Zhao, Yimei; Jiang, Jun; Ye, Wenjing published a patent.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Preparation of methylene violet derivatives as fluorescent probes for sulfide ion detection. And the patent contained the following:

The title compounds with general formula I•Cl- [wherein R1 = -NHCOCH2-R3, -NH(CH2O)n-R3, –NH(CH2NH)n-R3, -NH(CH2)n-R3, -N=N-(p-phenyl)-R3 or R3, where R3 is 7-nitro-4-(1-piperazinyl-4-yl)-2,1,3-benzoxadiazole; R2 = NH2 or N(Et)2; n = independently 1-12] were prepared as fluorescent probes. For example, compound II•Cl- was prepared in a multi-step synthesis. The fluorescent probe can be used for sulfide ion detection or preparing photodynamic therapy probe. The invention has good water solubility, high detection sensitivity, simple synthesis, mild condition, and low cost. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to preparation methylene violet derivative fluorescent probes sulfide ion detection, Heterocyclic Compounds (More Than One Hetero Atom): Pyridazines, Cinnolines, and Phthalazines and other aspects.Reference of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics