Washburn, Alex published the artcileDual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections, Category: chlorides-buliding-blocks, the publication is Bioorganic & Medicinal Chemistry Letters (2019), 29(13), 1665-1672, database is CAplus and MEDLINE.
Benzoxazolylphenyl sulfonamides I (R = Me, Ph, 2-thienyl, 2-FC6H4, 3-FC6H4, 4-FC6H4, 2-ClC6H4, 3-ClC6H4, 4-ClC6H4, 5-chloro-2-thienyl, 2-F3CC6H4, 3-F3CC6H4, 4-F3CC6H4, 3,4-Cl2C6H3, 4-F-3-F3CC6H3, 4-Cl-3-F3CC6H3, 4-Cl-3-O2NC6H3, 5-Cl-2-MeOC6H3, 2-MeC6H4, 3-MeC6H4, 4-MeC6H4, 4-EtC6H4, 4-H2C:CHC6H4, 2-MeOC6H4, 3-MeOC6H4, 4-MeOC6H4, 2-HOC6H4, 3-HOC6H4, 4-HOC6H4) and phenylbenzoxazolyl sulfonamides II (R = Me, Ph, 2-thienyl, 2-FC6H4, 3-FC6H4, 4-FC6H4, 2-ClC6H4, 3-ClC6H4, 4-ClC6H4, 5-chloro-2-thienyl, 2-F3CC6H4, 3-F3CC6H4, 4-F3CC6H4, 3,4-Cl2C6H3, 4-F-3-F3CC6H3, 4-Cl-3-F3CC6H3, 4-Cl-3-O2NC6H3, 5-Cl-2-MeOC6H3, 2-MeC6H4, 3-MeC6H4, 4-MeC6H4, 4-EtC6H4, 4-H2C:CHC6H4, 2-MeOC6H4, 3-MeOC6H4, 4-MeOC6H4, 2-HOC6H4, 3-HOC6H4, 4-HOC6H4) were prepared as dual inhibitors of GroEL/ES and the virulence factor protein tyrosine phosphatase B (PtpB) for the treatment of Mycobacterium tuberculosis infection at all stages of bacterial infection.
Bioorganic & Medicinal Chemistry Letters published new progress about 32333-53-2. 32333-53-2 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Sulfonyl chlorides,Benzene, name is 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, and the molecular formula is C15H21BO2, Category: chlorides-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics