Month: December 2022

Westerhaus, Felix A. published the artcileHeterogenized cobalt oxide catalysts for nitroarene reduction by pyrolysis of molecularly defined complexes, HPLC of Formula: 350-30-1, the publication is Nature Chemistry (2013), 5(6), 537-543, database is CAplus and MEDLINE.

Molecularly well-defined homogeneous catalysts are known for a wide variety of chem. transformations. The effect of small changes in mol. structure can be studied in detail and used to optimize many processes. However, many industrial processes require heterogeneous catalysts because of their stability, ease of separation, and recyclability, but these are more difficult to control on a mol. level. Here, we describe the conversion of homogeneous cobalt complexes into heterogeneous cobalt oxide catalysts via immobilization and pyrolysis on activated carbon. The catalysts thus produced are useful for the industrially important reduction of nitroarenes to anilines. The ligand indirectly controls the selectivity and activity of the recyclable catalyst and catalyst optimization can be performed at the level of the solution-phase precursor before conversion into the active heterogeneous catalyst.

Nature Chemistry published new progress about 350-30-1. 350-30-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Nitro Compound,Benzene, name is 3-Chloro-4-fluoronitrobenzene, and the molecular formula is C8H11NO, HPLC of Formula: 350-30-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Rezaeifard, Abdolreza published the artcileBenzyltributylammonium periodate as a novel and safe oxygen source for Mn-porphyrin catalyzed practical and highly selective oxygenation of hydrocarbons, SDS of cas: 23616-79-7, the publication is Polyhedron (2011), 30(13), 2303-2309, database is CAplus.

Benzyltributylammonium periodate (BzBu₃NIO₄) was prepared easily in high yield in neat water. The compound crystallized with two cations and two anions per asym. unit and a space group of Pna2₁ was determined by single-crystal x-ray diffraction. It was used practically in the clean and selective epoxidation of olefins and oxygenation of saturated hydrocarbons catalyzed by manganese (III) porphyrins in water/ethanol as a green media. The catalyst could be reused without noticeable loss of activity, and the oxidant’s byproduct (BzBu₃NIO₃) could also be reused. The efficiency of the oxidation system depends critically upon the steric hindrances and electronic structures of both the nitrogen donors and Mn-catalysts. Some evidences suggest the involvement of a high valent Mn-oxo species as well as a six-coordinate [(L)(Por)Mn-OIO₃] complex in the oxidation reactions.

Polyhedron published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, SDS of cas: 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ngoma Tchibouanga, Remi Rolland published the artcile3-Chloro-4-hydroxyphenylacetic acid co-crystals with nicotinamide, isonicotinamide, phenazine and 4,4′-bipyridine: An investigation of synthon motifs, Recommanded Product: 3-Chloro-4-hydroxyphenylacetic acid, the publication is Journal of Molecular Structure (2020), 127195, database is CAplus.

Multicomponent crystals of 3-chloro-4-hydroxyphenylacetic acid (CHPAA) with nicotinamide (NAM), isonicotinamide (INAM), phenazine (PHZN) and 4,4′-bipyridine (BIPY) were successfully synthesized by the slow evaporation technique. The co-crystals were characterized using x-ray diffraction, thermal anal., FTIR spectroscopy and Hirshfeld surface anal. Both NAM and INAM co-crystal structures exhibited O-H···N and N-H···O interactions. The INAM co-crystal structure demonstrated the tetrameric amide homosynthon. The incorporation of H₂O into the NAM co-crystal structure resulted in addnl. O-H···O H bonds. PHZ and BIPY co-crystal structures displayed O-H···N interactions. The 2CHPAA•BIPY structure also showed an interesting CHPAA dimer with a head to tail motif characterized by O-H···O and formed a H bonded ring described as R²₂(18). Weaker interactions C-H···O, C-H···Cl and π ··· π stacking were also observed in the crystal structures. Alternate preparation methods such as grinding and slurry experiments were also explored. Crystallog. data are given.

Journal of Molecular Structure published new progress about 33697-81-3. 33697-81-3 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Carboxylic acid,Benzene,Phenol, name is 3-Chloro-4-hydroxyphenylacetic acid, and the molecular formula is C8H7ClO3, Recommanded Product: 3-Chloro-4-hydroxyphenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Andrianov, K. A. published the artcileHydrolysis reaction of the higher alkylmethyldichlorosilanes, Application In Synthesis of 14799-94-1, the publication is Journal of Organometallic Chemistry (1967), 8(3), 443-50, database is CAplus.

Study of the hydrolysis reaction of higher alkylmethyl-dichlorosilanes shows that this reaction results in the formation of a mixture of cyclic and linear compounds Hydrolysis in HCl products only cyclic compounds, which can be vacuum distilled Condensation of the hydrolysis products of the higher alkyl-methyldichlorosilanes results in formation of a mixture of 6-, 8-, and 10-membered dialkyl cyclosiloxanes. In the chlorination of the dialkyl α,ω-dihydroxysiloxanes in the hydrolysis products of the (higher alkyl)methyldichlorosilanes, OH groups are replaced by Cl atoms.

Journal of Organometallic Chemistry published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C7H16Cl2Si, Application In Synthesis of 14799-94-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Andrianov, K. A. published the artcileHydrolysis reaction of the higher alkylmethyldichlorosilanes, Name: Dichloro(methyl)(octyl)silane, the publication is Journal of Organometallic Chemistry (1967), 8(3), 443-50, database is CAplus.

Study of the hydrolysis reaction of higher alkylmethyl-dichlorosilanes shows that this reaction results in the formation of a mixture of cyclic and linear compounds Hydrolysis in HCl products only cyclic compounds, which can be vacuum distilled Condensation of the hydrolysis products of the higher alkyl-methyldichlorosilanes results in formation of a mixture of 6-, 8-, and 10-membered dialkyl cyclosiloxanes. In the chlorination of the dialkyl α,ω-dihydroxysiloxanes in the hydrolysis products of the (higher alkyl)methyldichlorosilanes, OH groups are replaced by Cl atoms.

Journal of Organometallic Chemistry published new progress about 14799-93-0. 14799-93-0 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(methyl)(octyl)silane, and the molecular formula is C9H20Cl2Si, Name: Dichloro(methyl)(octyl)silane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Yan published the artcileIdentification of a hormone response element that mediates suppression of APOF by LXR and PPARα agonists, Synthetic Route of 637-07-0, the publication is Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids (2020), 1865(3), 158583, database is CAplus and MEDLINE.

Here we show in human liver C3A cells that APOF mRNA levels are reduced by agonists of LXR and PPARα nuclear receptors. This neg. regulation requires co-incubation with the RXR agonist, retinoic acid. Bioinformatic anal. of the ∼2 kb sequence upstream of the APOF promoter identified one potential LXR and 4 potential PPARα binding sites clustered between nucleotides -2007 and -1961. ChIP anal. confirmed agonist-dependent binding of LXRα, PPARα, and RXRα to this hormone response element complex (HREc). A luciferase reporter containing the 2 kb 5′ APOF sequence was neg. regulated by LXR and PPARα ligands as seen in cells. This regulation was maintained in constructs lacking the ∼1700 nucleotides between the HREc and the APOF proximal promoter. Mutations of the HREc that disrupted LXRα and PPARα binding led to the loss of reporter construct inhibition by agonists of these nuclear receptors. siRNA knockdown studies showed that APOF gene regulation by LXRα or PPARα agonists did not require an interaction between these two nuclear receptors. Thus, APOF is subject to neg. regulation by agonist-activated LXR or PPARα nuclear receptors binding to a regulatory element ∼1900 bases 5′ to the APOF promoter. High fat, cholesterol-enriched diets likely reduce APOF gene expression via these receptors interacting at this regulatory site.

Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids published new progress about 637-07-0. 637-07-0 belongs to chlorides-buliding-blocks, auxiliary class Inhibitor,Cell Cycle,PPAR, name is Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate, and the molecular formula is C12H15ClO3, Synthetic Route of 637-07-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sato, Masaru published the artcileSynthesis and Redox Behavior of Ruthenium(II) 2,3,4,5-Tetramethylruthenocenylacetylide and Related Complexes. Formation of μ-η⁶:η¹-[(Cyclopentadienylidene)ethylidene]diruthenium Complexes Containing a Strong Metal-Metal Interaction, COA of Formula: C5H10Cl3O3P, the publication is Organometallics (1999), 18(16), 3208-3219, database is CAplus.

1-Ethynyl-2,3,4,5-tetramethylruthenocene was prepared by the reaction of 1-formyl-2,3,4,5-tetramethylruthenocene with trimethylsilyldiazomethyllithium and also by the reaction of 1-(2′,2′-dichlorovinyl)-2,3,4,5-tetramethylruthenocene, which was obtained from the reaction of 1-formyl-2,3,4,5-tetramethylruthenocene with Li di-Et dichloromethylphosphonate and t-BuLi in good yield. 1-Ethynyl-2,3,4,5-tetramethylruthenocene reacted with RuClP₂L (P₂ = 2 PPh₃ or dppe; L = η-C₅H₅, η-C₅Me₅, or η⁵-C₉H₇) in the presence of NH₄PF₆ or AgBF₄, followed by column chromatog. on deactivated Al₂O₃, to give Ru(CCRc’)P₂L in moderate or good yields. Ru(CCRc)P₂(η⁵-C₉H₇) and Ru(CCRc^*)P₂(η⁵-C₉H₇) were similarly prepared (Rc, Rc’, and Rc^* are ruthenocenyl, 2,3,4,5-tetramethylruthenocenyl, and 1′,2′,3′,4′,5′-pentamethylruthenocenyl, resp.). The structures of Ru(CCRc’)(dppe)(PPh₃)₂(η-C₅H₅), Ru(CCRc)(dppe)(η⁵-C₉H₇), and Ru(CCRc’)(dppe)(η⁵-C₉H₇) were determined by x-ray anal. Cyclic voltammetry of the acetylide complexes showed two well-separated quasi-reversible waves. Chem. oxidation of Ru(II) 2,3,4,5-tetramethylruthenocenylacetylide complexes gave products whose stability was dependent on the ligand on the Ru(II) moiety. The ¹³C NMR spectrum of the oxidized species isolated as stable crystals confirmed the structural rearrangement of the bridging acetylide ligand to a μ-η⁶:η¹-[(cyclopentadienylidene)ethylidene] ligand. The structure of [(η-C₅H₅)Ru(μ-η⁶:η¹-C₅Me₄:C:C)Ru(dppe)(η⁵-C₅Me₅)](BF₄)₂ was determined by x-ray anal.

Organometallics published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, COA of Formula: C5H10Cl3O3P.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Takano, Seiichi published the artcileConcise enantioselective synthesis of acromelic acid A, HPLC of Formula: 18791-02-1, the publication is Journal of the American Chemical Society (1987), 109(18), 5523-4, database is CAplus.

A concise enantioselective synthesis of acromelic acid A (I), a potent neuroexcitory amino acid from the poisonous Japanese mushroom Clitocybe acromelalga, has been accomplished using (S)-O-benzylglycidol (II) as chiral template. The key step was the stereoselective intramol. cycloaddition of aziridine III at 200° to give pyrrolopyranone IV.

Journal of the American Chemical Society published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C5H5F3O2, HPLC of Formula: 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Pijper, Thomas C. published the artcilePosition and Orientation Control of a Photo- and Electrochromic Dithienylethene Using a Tripodal Anchor on Gold Surfaces, Synthetic Route of 219537-97-0, the publication is Journal of Physical Chemistry C (2015), 119(7), 3648-3657, database is CAplus.

A tripodal system for anchoring photochromic dithienylethenes on gold surfaces is reported. The self-assembled monolayers of a tripod-functionalized dithienylethene were characterized by cyclic voltammetry, surface-enhanced Raman spectroscopy (SERS), and XPS. These data are compared with solution studies, solid state Raman spectroscopy, and d. functional theory (DFT) calculations We show that the tripod-functionalized dithienylethene forms stable monolayers on gold in which all three legs of the tripod are adsorbed via the thiol units, thus providing a fixed position and orientation of the dithienylethene moiety with respect to the surface. Importantly, immobilization in this way allows for retention of both the photochem. and electrochem. functionality of the dithienylethene unit and reduces photochem. fatigue observed in solution

Journal of Physical Chemistry C published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Synthetic Route of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Palii, G. K. published the artcileStudy of Candida fungus sensitivity to antimicrobial drugs, Safety of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Antibiotiki i Meditsinskaya Biotekhnologiya (1986), 31(3), 218-20, database is CAplus.

Fifty strains of Candida (C. albicans 28, C. tropicalis 18, and C. pseudotropicalis 4 strains) were tested in vitro against 5 fungicides: amphotericin B, levorin, decamethoxine, enteroseptol, and intestopan. Decamethoxine was the most active drug, as it inhibited 78% of the strains at 0.08-6.25 μg/mL concentration; at 12.5 μg/mL, the drug showed fungicidal activity against 20% of the strains. Levorin and amphotericin B displayed antifungal activity at 50 μg/mL concentration At 3.9-7.8, μg/mL enteroseptol inhibited 78% of the strains. Intestopan was the least active compound Development of resistance to decamethoxine was slow, and there was no cross-resistance between decamethoxine and levorin.

Antibiotiki i Meditsinskaya Biotekhnologiya published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Safety of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics