Month: December 2022

Sadhukhan, Dipali published the artcileWeak Interactions Modulating the Dimensionality in Supramolecular Architectures in Three New Nickel(II)-Hydrazone Complexes, Magnetostructural Correlation, and Catalytic Potential for Epoxidation of Alkenes under Phase Transfer Conditions, Category: chlorides-buliding-blocks, the publication is Inorganic Chemistry (2011), 50(17), 8326-8339, database is CAplus and MEDLINE.

Three different ONO donor acetyl hydrazone Schiff bases have been synthesized from the condensation of acetic hydrazide with three different carbonyl compounds: salicylaldehyde (HL¹), 2-hydroxyacetophenone (HL²), and 2,3-dihydroxybenzaldehyde (HL³). These tridentate ligands are reacted with Ni(OOCCF₃)₂·xH₂O to yield three new Ni(II) complexes having distorted octahedral geometry at each Ni center: [Ni(L¹)(OOCCF₃)(CH₃OH)]₂ (1), [Ni(L²)(OOCCF₃)(H₂O)]₂ (2), and [Ni(L³)(L³H)](OOCCF₃)(H₂O)_1.65(CH₃OH)_0.35 (3). The ligands and the complexes have been characterized by elemental anal. and IR and UV-visible spectroscopy, and the structures of the complexes have been established by single crystal XRD study. 1 And 2 are centrosym. dinuclear complexes and are structural isomers whereas 3 is a bis chelated cationic monomer coordinated by one neutral and one monoanionic ligand. O-H···O hydrogen bonds in 3 give a dimer. Slight steric and electronic modifications in the ligand backbone provoke differences in the supramol. architectures of the complexes, leading to a variety of one, two, and three-dimensional hydrogen bonded networks in complexes 1–3, resp. Variable temperature magnetic susceptibility measurements reveal that moderate antiferromagnetic interactions operate between phenoxo bridged Ni(II) dimers in 1 and 2 whereas very weak antiferromagnetic exchange occurs through hydrogen bonding and π-π stacking interactions in 3. All complexes are efficient catalysts for the epoxidation of alkenes by NaOCl under phase transfer condition. The efficiency of alkene epoxidation is dramatically enhanced by lowering the pH, and the reactions are supposed to involve high valent Ni^III-OCl or Ni^III-O·intermediates. 3 Is the best epoxidation catalyst among the three complexes with 99% conversion and very high turnover number (TON, 396).

Inorganic Chemistry published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Balaraman, Harish Babu published the artcileKinetics and microwave-assisted extractive transesterification studies of high octane methyl esters (HOME) from karanja and chicken lard oil using protic deep eutectic solvent, Quality Control of 23616-79-7, the publication is Fuel (2020), 117299, database is CAplus.

The bio-conversion of fatty oils recovered from chicken waste and Karanja by both enzymic and microwave-assisted transesterification (MATE) into fatty acid Me esters (FAME) were performed in the present investigation. Evaluation of physicochem. properties and yield of biodiesel produced reveals the production of esters from chicken waste oil to be effective than the counterparts obtained from karanja oil. Intensification of transesterification process with chicken waste oil was carried out by employing protic deep eutectic solvents (pDES) for production of high octane Me esters (HOME). The thermophys. evaluation of synthesized pDES show low values of d., viscosity and refractive index which decrease with the further increase in temperature The use pDES reduces the mass transfer limitation in biodiesel formation at the lowest acyl acceptor ratio of 1:4. Response surface methodol. based optimization for microwave-assisted biodiesel production indicate the usage of the lowest power of 1.4 kW with a min. volume of pDES (8%) at the optimal time of 25 min yields 96.4% pure biodiesel. The composition of obtained biodiesel was evaluated with GC-MS. The resulting biodiesel obtained is suitable additive to mineral based fuels.

Fuel published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Quality Control of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Balaraman, Harish Babu published the artcileHigh selective purification of IgY from quail egg: Process design and quantification of deep eutectic solvent based ultrasound assisted liquid phase microextraction coupled with preparative chromatography, HPLC of Formula: 23616-79-7, the publication is International Journal of Biological Macromolecules (2020), 253-262, database is CAplus and MEDLINE.

The present research investigates on task-specific deep eutectic solvents (TDES) based aqueous two-phase extraction and purification of Igs by chromatog. from quail egg. The synthesis of TDES was accomplished with quaternary ammonium salt as hydrogen bond acceptor (HBA) and glycerol as hydrogen bond donor (HBD). Aqueous two-phase (ATPS) formation of TDESs with various salts was established and phase partitioning ability was evaluated using standard bovine Ig. Ultrasound-assisted liquid-liquid microextraction (UA-LLME) was performed with ATPS of better partitioning ability for quail egg yolk. Optimization of influential variables with response surface methodol. was accomplished and maximum yield was achieved for 85% (volume/volume) of NADES for feed of 18μg/mL of egg yolk isolate with ultrasound temperature of 35°C and 12 min contact time resp. The quantification of recovery was accomplished by gel filtration process with the determination of retention time, volume and resolution of separation using marker protein. Ultrapure Ig-Y (IgY) is achieved with anion exchange chromatog. and yield was calculated The results revealed that the selective concentration of Ig-Y from quail egg yolk could be performed using environment-friendly TDES based UA-LLME coupled with chromatog.

International Journal of Biological Macromolecules published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, HPLC of Formula: 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Pragathi, Yazala Jyothsna published the artcileIodine promoted synthesis and construction of aromatic thioureas from amines, Synthetic Route of 3696-23-9, the publication is European Journal of Biomedical and Pharmaceutical Sciences (2018), 5(7), 1-3, database is CAplus.

A new facile methodol. for the synthesis of thioureas by desulfurization and addition reaction of the required amines, carbon disulfide and ammonia solution in the presence of DMF solvent using iodine at room temperature The structures of the synthesized compounds were confirmed by IR, and ¹H-NMR methods. The synthetic benefits were operational simplicity, mild reaction conditions, short reaction times, high purity and yield of the products. Considering the com. importance of thioureas, it should be emphasized that implementation of the optimal synthesis of thiourea determined good intermediate for the synthesis heterocyclic compounds having good biol. activity from amines using iodine as a reagent.

European Journal of Biomedical and Pharmaceutical Sciences published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, Synthetic Route of 3696-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Darroudi, Mahdieh published the artcileSynthesis of Novel Triazole Incorporated Thiazolone Motifs Having Promising Antityrosinase Activity through Green Nanocatalyst CuI-Fe₃O₄@SiO₂ (TMS-EDTA), COA of Formula: C7H7ClN2S, the publication is Applied Organometallic Chemistry (2020), 34(12), e5962, database is CAplus.

In the present work, novel 5-((1-benzyl-1,2,3-triazol-4-yl)methoxybenzylidene)-2-(arylamino)thiazol-4-one thiazolone incorporated triazole derivatives I and II was designed as tyrosinase inhibitors. The compounds I and II were synthesized through click reaction in good yield. Moreover, the antityrosinas activity of the synthesized derivatives I and II was evaluated. In the search for establishing a click copper-catalyzed azide/alkyne cycloaddition (CuAAC) reaction under strict conditions, in terms of a novel air-stable, a recyclable and efficient magnetic catalyst was planned for new triazole derivatives as a well-organized copper iodide supported on the functionalized Fe₃O₄@SiO₂ core-shell (CuI/Fe₃O₄@SiO₂(TMS-EDTA) nanoparticles). The engineered nanocatalyst synthesized for the first time and characterized by different methods, including FT-IR spectroscopy, XRD, FESEM, EDX, TEM, TGA, and BET anal. The excellent catalytic performance in ethanol with high surface area (351.7 m²g^-1) and short reaction time for diverse functional groups (120-200 min), no use of toxic solvents, reusability of the catalyst, and using eco-friendly conditions were the advantageous of this work. Moreover,the nanocatalyst was used at least five times without any significant decrease in the yield of the reaction. The thiazolidine-triazole derivatives I [X=Y=Z = H, X=Y = H; Z = Br, X = 4-N; Y = H; Z = 2-Cl and X = 4-N; Y = H; 3,4-di-Cl] showed promising tyrosinase inhibitory activity with IC₅₀ values in the range of 5.90-9.81μM. The compounds I and II were found to be considerably more potent tyrosinase inhibitors than the reference inhibitor kojic acid (IC₅₀ = 18.36μM).

Applied Organometallic Chemistry published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H7ClN2S, COA of Formula: C7H7ClN2S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ahn, Ki Chang published the artcileDetection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay, Category: chlorides-buliding-blocks, the publication is Environmental Science & Technology (2016), 50(7), 3754-3761, database is CAplus and MEDLINE.

A sensitive, competitive ELISA for the detection of the antimicrobial triclosan (TCS) was developed. Novel immunizing haptens were synthesized by derivatizing at the 4-Cl position of the TCS mol. Compounds derived from substitutions at 4′-Cl and that replaced the 2′-OH with a Cl atom were designed as unique coating antigen haptens. Polyclonal rabbit antisera were screened against the coating antigen library to identify combinations of immunoreagents resulting in the most sensitive assays. The most sensitive assay identified was one utilizing antiserum number 1155 and a heterologous competitive hapten, where the 2′-OH group was substituted with a Cl atom. An IC₅₀ value and the detection range for TCS in assay buffer were 1.19 and 0.21-6.71 μg/L, resp. The assay was selective for TCS, providing low cross-reactivity (<5%) to the major metabolites of TCS and to brominated di-Ph ether-47. A 2nd assay using a competitive hapten containing Br instead of Cl substitutions was broadly selective for both brominated and chlorinated diphenylethers. Using the most sensitive assay combination, we measured TCS concentrations in water following dilution Biosolid samples were analyzed following the dilution of a simple solvent extract The immunoassay results were similar to those determined by LC-MS/MS. This immunoassay can be used as a rapid and convenient tool to screen for human and environmental exposure.

Environmental Science & Technology published new progress about 350-30-1. 350-30-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Nitro Compound,Benzene, name is 3-Chloro-4-fluoronitrobenzene, and the molecular formula is C6H3ClFNO2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

O’Hagan, Michael P. published the artcileVisible-light photoswitching of ligand binding mode suggests G-quadruplex DNA as a target for photopharmacology, Formula: C15H14Cl2S2, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(38), 5186-5189, database is CAplus and MEDLINE.

We report the selective targeting of telomeric G4 DNA with a dithienylethene ligand and demonstrate the robust visible-light mediated switching of the G4 ligand binding mode and G-tetrad structure in physiol.-relevant conditions. The toxicity of the ligand to cervical cancer cells is modulated by the photoisomeric state of the ligand, indicating for the first time the potential of G4 to serve as a target for photopharmacol. strategies.

Chemical Communications (Cambridge, United Kingdom) published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Formula: C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Prasad, G. K. published the artcileSun light assisted photocatalytic decontamination of sulfur mustard using ZnO nanoparticles, Application of 1,2-Bis(2-chloroethyl)disulfane, the publication is Journal of Molecular Catalysis A: Chemical (2011), 349(1-2), 55-62, database is CAplus.

Sunlight-assisted photocatalytic decontamination of sulfur mustard (HD) was studied using ZnO nanoparticles and the data were compared with those carried out in the presence of UVA and visible light radiation. In the presence of sunlight, 100% of HD was decomposed in 12 h. Whereas, in the presence of UVA light 90%, and in visible light 80% of HD was decomposed in 12 h. GC-MS data indicated the formation of thiodiglycol, hemisulfur mustard, divinyl sulfide, 2-chloro Et vinyl sulfide, etc., on the surface of ZnO nanoparticles in the case of dark and visible light irradiation experiments However, in sunlight and UVA light irradiation experiments, GC-MS data indicated the formation of HD sulfoxide, HD sulfone, 1,3-dithiane, 2-chloro ethanol, acetaldehyde, CO₂, etc. along with hydrolysis and elimination products. Under the illumination of visible light and in dark hydrolysis, elimination and surface complexation reactions contributed to decontamination of HD. Whereas, in the presence of sunlight and UVA light, photocatalytic reactions like C-S bond cleavage, oxidation of C, S atoms were observed to have contributed to decontamination of HD in addition to hydrolysis and elimination reactions.

Journal of Molecular Catalysis A: Chemical published new progress about 1002-41-1. 1002-41-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 1,2-Bis(2-chloroethyl)disulfane, and the molecular formula is C4H8Cl2S2, Application of 1,2-Bis(2-chloroethyl)disulfane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Comstock, Lindsay R. published the artcileExpeditious synthesis of aziridine-based cofactor mimics, Name: 2,3-Dibromopropionylchloride, the publication is Tetrahedron (2002), 58(30), 6019-6026, database is CAplus.

S-Adenosyl-L-methionine mimics were synthesized in a linear fashion highlighting methodol. that bypasses the need for adenine base protection. These aziridine-based cofactor mimics are envisioned as useful biochem. tools and potential therapeutic agents whose mechanism of action hinges upon aberrant methyltransferase enzymes. Aziridination of the 5′ position of adenosine was effected by convergence of suitably protected 5′-aminoadenosine with various dibromopropionates. The economy and high yields for this route to said aziridine-based cofactors is highly amenable to large-scale chem. which no doubt will be vital to their development as therapeutics and biochem. tools.

Tetrahedron published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Name: 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Geetanjali, Y. published the artcileFurano compounds: synthesis of aroylbenzofurans, benzo[1,2-b:5,4-b’]difurans and their basic ethers, Product Details of C5H13Cl2N, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1985), 24B(11), 1129-32, database is CAplus.

Alkylaminoalkoxybenzofurans I (R = CH₂CH₂NR¹R², CHMeCH₂NMe₂, 3-piperidinopropyl; NR¹R² = NMe₂, NEt₂, pyrrolidino, piperidino, morpholino) have been synthesized by condensing I (R = H) with RCl.HCl in the presence of K₂CO₃ in dry Me₂CO. I (R = H) was obtained by refluxing 1,3-Ac₂C₆H₂(OH)₂-4,6 with BrCH₂Bz. Dibenzoylbenzo[1,2-b:5,4-b‘]difurans II (R³ = H, OMe, OH, OR) have also been synthesized. Condensation of BrCH₂Bz with 5-acetyl-6-hydroxy-2,3-diphenylbenzofuran results in 6-benzoyl-5-methyl-2,3-diphenylbenzo[1,2-b:5,4-b‘]difuran.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C5H13Cl2N, Product Details of C5H13Cl2N.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics