Mooibroek, Tiddo J. published the artcileA threading receptor for polysaccharides, Safety of Pyrene-2-carboxylic acid, the main research area is receptor polysaccharide cellulose oligosaccharide monosaccharide preparation polypseudorotaxane chitosan.
Cellulose, chitin and related polysaccharides are key renewable sources of organic mols. and materials. However, poor solubility tends to hamper their exploitation. Synthetic receptors could aid dissolution provided they are capable of cooperative action, for example by multiple threading on a single polysaccharide mol. Here we report a synthetic receptor designed to form threaded complexes (polypseudorotaxanes) with these natural polymers. The receptor binds fragments of the polysaccharides in aqueous solution with high affinities (Ka up to 19,000 M-1), and is shown-by nuclear Overhauser effect spectroscopy-to adopt the threading geometry. Evidence from induced CD and at. force microscopy implies that the receptor also forms polypseudorotaxanes with cellulose and its polycationic analog chitosan. The results hold promise for polysaccharide solubilization under mild conditions, as well as for new approaches to the design of biol. active mols.
Nature Chemistry published new progress about Oligosaccharides Role: FMU (Formation, Unclassified), PRP (Properties), FORM (Formation, Nonpreparative). 36428-96-3 belongs to class chlorides-buliding-blocks, name is Pyrene-2-carboxylic acid, and the molecular formula is C17H10O2, Safety of Pyrene-2-carboxylic acid.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics