Xu, Liang published the artcileOxidative cyclization of N-alkyl-o-methyl-arenesulfonamides to biologically important saccharin derivatives, HPLC of Formula: 7079-48-3, the main research area is ortho methylarenesulfonamide oxidative cyclization saccharin derivative synthesis; benzisothiazole dioxide synthesis oxidative cyclization ortho methylarenesulfonamide.
Various biol. important saccharin skeletons and their N-alkyl derivatives were efficiently prepared by Cr(VI) oxide-catalyzed H5IO6 oxidation of N-alkyl-o-methyl-arenesulfonamides in MeCN. N-tert-Bu saccharin skeletons were easily prepared by H5IO6-CrO3 oxidation of N-tert-butyl-o-Me arenesulfonamides in the presence of acetic anhydride. The method that furnished the novel fluoro- and trifluoromethyl-substituted saccharin skeletons was characterized by two steps, a simple work-up procedure, a single purification and good overall yields from substituted toluene derivatives For example, 58 % 2-tert-butyl-6-trifluoromethyl-1,2-benzisothiazol-3-one 1,1-dioxide was obtained from 1-methyl-4-(trifluoromethyl)benzene.
Tetrahedron published new progress about Heterocyclization (oxidative). 7079-48-3 belongs to class chlorides-buliding-blocks, name is 4-Fluoro-2-methylbenzene-1-sulfonyl chloride, and the molecular formula is C7H6ClFO2S, HPLC of Formula: 7079-48-3.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics