Toyota, Kozo published the artcileUnexpected formation of 4,7-dihalobenzo[b]thiophenes using Ohira-Bestmann reagent and reactivity of the halogen-substituted benzo[b]thiophenes in Suzuki-Miyaura coupling with phenylboronic acid, HPLC of Formula: 886615-30-1, the main research area is phenyl halobenzothiophene preparation regioselective; phenylboronic acid dihalobenzothiophene Suzuki coupling palladium catalyst.
Reaction of 2-(1-adamantylsulfanyl)-3,6-dihalobenzaldehydes 2-X-5-Y-6-SR1C6H2CHO (X = Br, I, Cl, H, Ph; Y = Br, I, Cl, H; R1 = adamantan-1-yl) with Ohira-Bestmann reagent gave 4,7-dihalobenzo[b]thiophenes I along with normal alkyne products 2-X-5-Y-6-SR1C6H2CC . Nine types of 4,7-dihalobenzo[b]thiophenes I bearing chlorine, bromine, or iodine atoms, were prepared by this method. Regioselectivity in Suzuki-Miyaura cross coupling reactions of the 4,7-dihalobenzo[b]thiophenes I with PhB(OH)2 was also studied.
Heterocycles published new progress about Aromatic hydrocarbons, aryl alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 886615-30-1 belongs to class chlorides-buliding-blocks, name is 3-Bromo-6-chloro-2-fluorobenzaldehyde, and the molecular formula is C7H3BrClFO, HPLC of Formula: 886615-30-1.
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics