I found the field of Chemistry very interesting. Saw the article Unified Protocol for Fe-Based Catalyzed Biaryl Cross-Couplings between Various Aryl Electrophiles and Aryl Grignard Reagents published in 2019.0. Quality Control of 1-Chloro-2-methylbenzene, Reprint Addresses Duan, XF (corresponding author), Beijing Normal Univ, Coll Chem, Beijing 100875, Peoples R China.. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene
The combination of commonly used FeCl3/SIPr with Ti(OEt)(4)/PhOM enabled a highly general iron- based catalyst system, which could efficiently catalyze the biaryl coupling reaction between various electrophiles (I, Br, Cl, OTs, OCONMe2, OSO2NMe2) and common or functionalized aryl Grignard reagents with high functional group tolerance. Selective couplings of aryl iodides and bromides over the corresponding oxygen-based electrophiles have been achieved, and thus a terphenyl acid intermediate for anidulafungin was conveniently synthesized via an orthogonal coupling strategy.
Welcome to talk about 95-49-8, If you have any questions, you can contact Wang, L; Wei, YM; Zhao, Y; Duan, XF or send Email.. Quality Control of 1-Chloro-2-methylbenzene
Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics