Tag: M.W=300-350

Ahlers, Patrick published the artcileDynamic Light Scattering Investigation of the Kinetics and Fidelity of Supramolecular Copolymerizations in Water, Category: chlorides-buliding-blocks, the publication is Macromolecules (Washington, DC, United States) (2017), 50(19), 7712-7720, database is CAplus.

The self-assembly of supramol. copolymers facilitates the preparation of multifunctional materials, with tunable mech., electronic, or bioactive properties. Compared to covalent copolymerization protocols, controlling the mol. weight, stability, and monomer sequence of a multicomponent supramol. copolymer remains limited. Here, we report a light scattering investigation of the charge-regulated supramol. copolymerization in neutral buffer of physiol. ionic strength, supported with electron microscopy and CD spectroscopy experiments Dendritic anionic and cationic peptide comonomers self-assemble into AB-type heterocopolymers with a nanorod-like morphol., a thickness of 11 nm, and a mean length of up to 70 nm. The fidelity in the copolymerization is remarkably high, and excess of either monomer of up to 50 mol % in the feed ratio does not lead to chain stoppering. The narrow length distribution of the copolymers (D < 1.3) and high colloidal stability in physiol. buffer support their applications as biomedical carrier materials.

Macromolecules (Washington, DC, United States) published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhang, Liyun published the artcile“Orange alert”: A fluorescent detector for bisphenol A in water environments, Computed Properties of 42074-68-0, the publication is Analytica Chimica Acta (2014), 51-56, database is CAplus and MEDLINE.

Due to the prevalent use of polycarbonate plastics and epoxy resins in packaging materials and paints for ships, there has been a widespread global contamination of environmental water sources with bisphenol A (BPA). BPA, an endocrine disruptor, has been found to cause tremendous health problems. Therefore, there is an urgent need for detecting BPA in a convenient and sensitive manner to ensure water safety. Herein, we develop a fluorescent turn-on BPA probe, named Bisphenol Orange (BPO), which could conveniently detect BPA in a wide variety of real water samples including sea water, drain water and drinking water. BPO shows superior selectivity toward BPA and up to 70-fold increase in fluorescence emission at 580 nm when mixed with BPA in water. Mechanistic studies suggest a plausible water-dependent formation of hydrophobic BPA clusters which favorably trap and restrict the rotation of BPO and recover its inherent fluorescence.

Analytica Chimica Acta published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C7H4BrClO2, Computed Properties of 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Steenbock, Torben published the artcilePhotoswitching Behavior of a Cyclohexene-Bridged versus a Cyclopentene-Bridged Dithienylethene System, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is ChemPhysChem (2015), 16(7), 1491-1501, database is CAplus and MEDLINE.

Photoswitching is an intriguing way of incorporating functionality into mols. or their subunits. Dithienylethene switches are particularly promising, but have so far mostly been studied with five-membered ring (cyclopentenyl) backbones. We aim at comparing the switching properties of backbones with five and six carbon atoms in the ring. A major advantage is that cyclohexenyl rings offer new options for chiral functionalization. A slight change in the reaction conditions of a McMurry ring closure reaction leads to the formation of dithienyl derivatives with a cyclohexene backbone in reasonable yield. D. functional theory calculations were carried out, demonstrating the similarity of both compounds Exptl. results confirm the theor. outcomes.

ChemPhysChem published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C14H26O2, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liang, Jun published the artcileChemical synthesis of Ub-AMC via ligation of peptide hydrazides, SDS of cas: 42074-68-0, the publication is Science China: Chemistry (2013), 56(9), 1301-1306, database is CAplus.

The C-terminal conjugate of ubiquitin with 7-amino-4-methylcoumarin (Ub-AMC) is an important probe for fluorescence-based anal. of deubiquitinating enzyme (DUB) activity. It is important to develop more efficient methods for the preparation of Ub-AMC because the currently available technol. is still expensive for scaled-up production In the present work we report an efficient strategy for total chem. synthesis of Ub-AMC through ligation of peptide hydrazides. Three peptide segments are assembled via N-to-C sequential ligation and the resulting product is converted to Ub-AMC via TCEP-mediated desulfurization. The synthetic Ub-AMC is shown to have expected biol. functions through the measurement of its DUB activity.

Science China: Chemistry published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, SDS of cas: 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mahvidi, S. published the artcileInfluence of protonation on the photochromic behavior, phase transfer and thermal stability of phenylamine-substituted diarylethenes, Category: chlorides-buliding-blocks, the publication is Progress in Color, Colorants and Coatings (2020), 13(2), 105-119, database is CAplus.

This paper examines the role of protonation on the photochromic reactions of multi-responsive Ph amine diarylethene derivatives (PA-DAEs). Reversible protonation and deprotonation provide a secondary stimulus for controlling the properties of light-responsive PA-DAEs, including solubility and thermal stability. For this reason, the phenylamine substituted DAEs were synthesized using a novel and efficient microwave-assisted synthetic route. Steady-state spectroscopy results indicated that the photocyclization and photocycloreversion reactions were reversible at different pH values. Even though, the acidic condition caused red-shift of the visible light absorption bands and generated a new absorption band at near-IR to IR region in the closed-ring structure but made blue-shift in the absorption spectra of the open-ring isomers. Also, it was showed that the excess amount of proton locked back the photochromic reaction. Results also indicated that the protonated closed-ring isomers of PA-DAEs are hydrophilic, whereas the deprotonated forms and protonated open-ring forms are hydrophobic. In addition to photoswitching and solubility of PA-DAEs under irradiation at different light wavelengths, the thermal stability of P-type PA-DAEs was also monitored in the presence of trifluoroacetic acid at different temperatures as external stimuli.

Progress in Color, Colorants and Coatings published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Barman, Siti published the artcileNMR, surface tension and conductance study to investigate host-guest inclusion complexes of three sequential ionic liquids with β-cyclodextrin in aqueous media, Quality Control of 23616-79-7, the publication is Chemical Physics Letters (2016), 43-50, database is CAplus.

Host-guest inclusion complexes of 3 sequential cationic room temperature surface active ionic liquids, benzyltrialkylammonium chloride [(C₆H₅CH₂)N(C_nH_2n+1)₃Cl; where n = 1, 2, 4] with β-cyclodextrin in aqueous media have been studied using surface tension, conductance and NMR spectroscopy. All the studies suggested that the hydrophobic benzyl group of ionic liquids is encapsulated inside into the cavity of β-cyclodextrin and played a crucial role in supporting the formation of inclusion complexes. The variation of the thermodn. parameters with guest size, shape is used to draw inferences about contributions to the overall binding by the driving forces, viz., hydrophobic effect, steric hindrance, van der Waal force, and electrostatic force.

Chemical Physics Letters published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Quality Control of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Bonacchi, Sara published the artcileSurface-Induced Selection During In Situ Photoswitching at the Solid/Liquid Interface, Category: chlorides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2015), 54(16), 4865-4869, database is CAplus and MEDLINE.

Here we report for the first time a submolecularly resolved scanning tunneling microscopy (STM) study at the solid/liquid interface of the in situ reversible interconversion between two isomers of a diarylethene photoswitch, i.e., open and closed form, self-assembled on a graphite surface. Prolonged irradiation with UV light led to the in situ irreversible formation of another isomer as byproduct of the reaction, which due to its preferential physisorption accumulates at the surface. By making use of a simple yet powerful thermodn. simulation, physicochem. we provide a quant. description for the observed surface-induced selection of one isomeric form.

Angewandte Chemie, International Edition published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Al Musaimi, Othman published the artcileBypassing osmotic shock dilemma in a polystyrene resin using the green solvent cyclopentyl methyl ether (CPME): a morphological perspective, Quality Control of 42074-68-0, the publication is Polymers (Basel, Switzerland) (2019), 11(5), 874, database is CAplus and MEDLINE.

The “osmotic shock” phenomenon is the main thing that is responsible for morphol. structure alteration, which can jeopardize the use of a polymer in a chem. process. This is extremely important in solid-phase peptide synthesis (SPPS), which is the method of choice for the preparation of these important biol. active compounds Herein, we have used Hildebrand solubility parameters (d) to investigate the influence of different ethers that are used in the precipitation step of the SPPS using a polystyrene resin. The green cyclopentyl Me ether (CPME) has shown to be slightly superior to 2-methyltetrahydrofurane, which is also a green ether and clearly better than the hazardous di-Et ether and tert-Bu Me ether. These results have been corroborated by scanning electron microscope (SEM) anal. and computational studies. All together, these confirm the adequacy of CPME for being the ether of choice to be used in SPPS.

Polymers (Basel, Switzerland) published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Quality Control of 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Subiros-Funosas, Ramon published the artcileUse of Oxyma as pH modulatory agent to be used in the prevention of base-driven side reactions and its effect on 2-chlorotrityl chloride resin, Category: chlorides-buliding-blocks, the publication is Biopolymers (2012), 98(2), 89-97, database is CAplus and MEDLINE.

The presence of low pKa N-hydroxylamines is beneficial in peptide chem. as they reduce some base-mediated side reactions. Here we evaluated the applicability and buffering capacity of Et 2-cyano-2-(hydroxyimino)acetate (Oxyma) in the prevention of aspartimide/piperidide formation and Pro-based overcoupling and compared it with the performance of HOBt and HOAt. In addition, the compatibility of these additives with the highly acid-labile 2-chlorotrityl chloride resin is examined © 2011 Wiley Periodicals, Inc. Biopolymers, 2011.

Biopolymers published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C4H6N2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Xiao-Gang published the artcileA multifunctional metal-organic framework based tumor targeting drug delivery system for cancer therapy, COA of Formula: C19H14Cl2, the publication is Nanoscale (2015), 7(38), 16061-16070, database is CAplus and MEDLINE.

Drug delivery systems (DDSs) with biocompatibility and precise drug delivery are eagerly needed to overcome the paradox in chemotherapy that high drug doses are required to compensate for the poor biodistribution of drugs with frequent dose-related side effects. In this work, we reported a metal-organic framework (MOF) based tumor targeting DDS developed by a one-pot, and organic solvent-free “green” post-synthetic surface modification procedure, starting from the nanoscale MOF MIL-101. Owing to the multifunctional surface coating, premature drug release from this DDS was prevented. Due to the pH responsive benzoic imine bond and the redox responsive disulfide bond at the modified surface, this DDS exhibited tumor acid environment enhanced cellular uptake and intracellular reducing environment triggered drug release. In vitro and in vivo results showed that DOX loaded into this DDS exhibited effective cancer cell inhibition with much reduced side effects.

Nanoscale published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C10H9NO, COA of Formula: C19H14Cl2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics