Tag: M.W=300-350

Veisi, Hojat published the artcileHighly efficient method for synthesis of bis(indolyl)methanes catalyzed by FeCl₃-based ionic liquid, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Journal of the Chinese Chemical Society (Taipei, Taiwan) (2009), 56(2), 240-245, database is CAplus.

A reaction of benzyltriethylammonium chloride with iron chloride (FeCl₃) gave an ionic liquid compound [i.e., N,N,N-triethylbenzenemethanaminium tetrachloroferrate]. A method for the synthesis of the title compounds [i.e, 3,3′-(phenylmethylene)bis[1H-indole] derivatives] is reported here. A highly efficient green protocol involved a reaction of indole with with aldehydes and ketones in the presence of and ionic liquid These liquids serve as efficient media as well as Lewis acid catalysts.

Journal of the Chinese Chemical Society (Taipei, Taiwan) published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C12H10F2Si, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Karthiraj, T. published the artcileTask-specific deep eutectic solvent based extraction coupled cascade chromatography quantification of α-glucosidase inhibitory peptide from Ocimum tenuriflorum seeds, HPLC of Formula: 23616-79-7, the publication is Microchemical Journal (2020), 104883, database is CAplus.

A sustainable method for purification and quantification of α-glucosidase inhibitory peptides from Ocimum tenuriflorum is described in the present investigation. Nine tailor-made DESs under diverse categories were synthesized and their thermophys. properties were determined Selective extraction of these therapeutic peptides using sustainable DESs is carried out. Three DESs having better phase ratios were selected and their partition coefficient was assessed with a tripeptide as a marker. Ultrasound-assisted liquid-phase microextraction (UA-LPME) based purification of bioactive peptides is performed. Further, response surface methodol. based optimization for effective isolation of α-amylase inhibitory peptide from mango seed hydrolyzate for DES formed with carnitine and maltose was determined as 96%. Preparative purification (43μg/g) of bioactive peptides was carried out with size exclusion chromatog. The preconcd. fractions were exposed to anion exchange chromatog. and ultrapure peptides (88%) with high inhibitory activity were obtained. α-amylase inhibition kinetics was established for the resultant ultrapure bioactive peptides to evaluate and quantify its inhibitory property.

Microchemical Journal published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, HPLC of Formula: 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Itsuno, Shinichi published the artcileSynthesis of chiral iridium complexes immobilized on amphiphilic polymers and their application to asymmetric catalysis, Product Details of C19H34ClN, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2014), 52(21), 3037-3044, database is CAplus.

This article details the enantioselective catalytic performance of crosslinked, polymer immobilized, Ir-based, chiral complexes for transfer hydrogenation of cyclic imines to chiral amines. Polymerization of the achiral vinyl monomer, divinylbenzene, and a polymerizable chiral 1,2-diamine monosulfonamide ligand followed by complexation with [IrCl₂Cp*]₂ affords the crosslinked polymeric chiral complex, which can be successfully applied to asym. transfer hydrogenation of cyclic imines. Polymeric catalysts prepared from amphiphilic achiral monomers have high catalytic activity in the reaction and can be used both in organic solvents and water to give chiral cyclic amines with a high level of enantioselectivity (up to 98% ee). The asym. reaction allows for reuse of the heterogeneous catalyst without any loss in activity or enantioselectivity over several runs. © 2014 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2014.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Product Details of C19H34ClN.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ghiani, S. published the artcileSynthesis, radiolabeling, and pre-clinical evaluation of [⁴⁴Sc]Sc138995-P-AAZTA conjugate PSMA inhibitor, a new tracer for high-efficiency imaging of prostate cancer, SDS of cas: 42074-68-0, the publication is European Journal of Nuclear Medicine and Molecular Imaging (2021), 48(8), 2351-2362, database is CAplus and MEDLINE.

The aim of this work was to demonstrate the suitability of AAZTA conjugated to PSMA inhibitor (B28110) labeled with scandium-44 as a new PET tracer for diagnostic imaging of prostate cancer. Nowadays, scandium-44 has received significant attention as a potential radionuclide with favorable characteristics for PET applications. A polyaminopolycarboxylate heptadentate ligand based on a 1,4-diazepine scaffold (AAZTA) has been thoroughly studied as chelator for Gd3+ ions for MRI applications. The excellent results of the equilibrium, kinetic, and labeling studies led to a preliminary assessment of the in vitro and in vivo behavior of [44Sc][Sc-(AAZTA)]- and two derivatives, i.e., [44Sc][Sc (CNAAZTA-BSA)] and [44Sc][Sc (CNAAZTA-cRGDfK)]. Results: B28110 was synthesized by hybrid approach, combining solid-phase peptide synthesis (SPPS) and solution chem. to obtain high purity (97%) product with an overall yield of 9%. Subsequently, the radioactive labeling was performed with scandium-44 produced from natural calcium target in cyclotron, in good radiochem. yields (RCY) under mild condition (pH 4, 298 K). Stability study in human plasma showed good RCP% of [44Sc]Sc-B28110 up to 24 h (94.32%). In vivo PET/MRI imaging on LNCaP tumor-bearing mice showed high tracer accumulation in the tumor regions as early as 20 min post-injection. Ex vivo biodistribution studies confirmed that the accumulation of 44Sc-PSMA-617 was two-fold lower than that of the radiolabeled B28110 probes. This work demonstrated the suitability of B28110 for the complexation with scandium-44 at room temperature and the high performance of the resulting new tracer based on AAZTA chelator for the diagnosis of prostate cancer using PET.

European Journal of Nuclear Medicine and Molecular Imaging published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, SDS of cas: 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Duraisamy, Thirumalai published the artcileTransition metal halide compounds: 1. Octahedral hexatantalum halide clusters, Synthetic Route of 23616-79-7, the publication is Inorganic Syntheses (2014), 1-8, database is CAplus.

The preparation of octahedral hexatantalum halide clusters is described. Thus, reaction of TaCl₅ with Ga⁺GaCl₄^– in the presence of NaCl gave Na₄[Ta₆(μ-Cl)₁₂Cl₆] which on hydrolysis gave Ta₆(μ-Cl)₁₂Cl₂(OH₂)₄·4H₂O. Reaction of later complex with [N(CH₂Ph)Bu₃]Cl gave [N(CH₂Ph)Bu₃]₄[Ta₆(μ-Cl)₁₂Cl₂].

Inorganic Syntheses published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Synthetic Route of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mei, Leixia published the artcileSupramolecular self-assembly of fluorescent peptide amphiphiles for accurate and reversible pH measurement, Quality Control of 42074-68-0, the publication is Organic & Biomolecular Chemistry (2019), 17(4), 939-944, database is CAplus and MEDLINE.

We report the synthesis and self-assembly of fluorescent peptide amphiphiles (NBD-PA) composed of a fluorescent NBD probe and a peptide derivative VVAADD with a C₁₂-alkyl-chain as the linker (NBD-C₁₂-VVAADD). The self-assembly of NBD-PA formed beta-sheet structures at neutral pH in aqueous solution, contributed to an âˆ?0-fold increase in the fluorescence and quantum yield of NBD mols., and conferred a supramol. hydrogel with excellent viscoelastic properties, while gel-to-sol transition of NBD-PA occurred rapidly when the pH value was adjusted to strongly alk. (e.g. pH 11). Through the pH-responsive self-assembly behavior, we further explored the relation between fluorescence of NBD-PA and pH values. Interestingly, the fluorescence of the NBD-PA system exhibited an excellent sigmoidal function relation (R² = 0.9999) with the alk. pH values, which enabled accurate pH measurement regardless of salt types and ionic strength of solvents. Furthermore, the fluorescence of NBD-PA was fully reversible upon cycles of pH shifts, with the chem. structure of NBD-PA well-maintained throughout the process. These features of NBD-PA would facilitate the design of in situ pH detection systems as well as pH-responsive actuators for various applications in future.

Organic & Biomolecular Chemistry published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Quality Control of 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chai, Xianzhi published the artcileTargeted photoswitchable imaging of intracellular glutathione by a photochromic glycosheet sensor, Related Products of chlorides-buliding-blocks, the publication is Beilstein Journal of Organic Chemistry (2019), 2380-2389, database is CAplus and MEDLINE.

The development of photochromic fluorescence sensors with dynamic and multiple-signaling is beneficial to the improvement of biosensing/imaging precision. However, elaborate designs with complicated mol. structures are always required to integrate these functions into one mol. By taking advantages of both redox-active/high loading features of two-dimensional (2D) manganese dioxide (MnO₂) and dynamic fluorescence photoswitching of photochromic sensors, we here design a hybrid photochromic MnO₂ glycosheet (Glyco-DTE@MnO₂) to achieve the photoswitchable imaging of intracellular glutathione (GSH). The photochromic glycosheet manifests significantly turn-on fluorescence and dynamic ON/OFF fluorescence signals in response to GSH, which makes it favorable for intracellular GSH double-check in targeted human hepatoma cell line (HepG2) through the recognition between β-D-galactoside and asialoglycoprotein receptor (ASGPr) on cell membranes. The dynamic fluorescence signals and excellent selectivity for detection and imaging of GSH ensure the precise determination of cell states, promoting its potential applications in future disease diagnosis and therapy.

Beilstein Journal of Organic Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Li, Ziyong published the artcileConstruction of photoswitchable rotaxanes and catenanes containing dithienylethene fragments, Related Products of chlorides-buliding-blocks, the publication is Organic & Biomolecular Chemistry (2015), 13(26), 7313-7322, database is CAplus and MEDLINE.

Mech. interlocked structures such as rotaxanes and catenanes provide a novel backbone for constructing functional materials with unique structural characteristics. In this study, we have designed and synthesized a series of photoswitchable rotaxanes and catenanes containing photochromic dithienylethene fragments using a template-directed clipping approach based on dynamic imine chem. Their structures have been confirmed using NMR, mass spectrometry and elemental anal. Investigations into their photoisomerization properties indicated that these dithienylethene-based mech. interlocked mols. have good reversibility and excellent fatigue resistance upon irradiation with UV or visible light. Interestingly, the mech. interlocked mols. containing two dithienylethene backbones display around a 2-fold increase in the molar absorption coefficient compared with that of the mono dithienylethene derivative Furthermore, the introduction of the fluorophore pyrene in the dithienylethene component facilitates these mols. to serve as fluorescent switches.

Organic & Biomolecular Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Brueckner, Alexander C. published the artcileVisible-light-mediated, nitrogen-centered radical amination of tertiary alkyl halides under metal-free conditions to form α-tertiary amines, Application of 2-Chlorotrityl chloride, the publication is Organic & Biomolecular Chemistry (2016), 14(19), 4387-4392, database is CAplus and MEDLINE.

A mild and operationally convenient amino-functionalization of a range of tertiary alkyl halides by reaction with iminoiodinanes (PhI=NNs) and I₂ was developed. According to the mechanistic experiments described within the reaction was speculated to proceed through a light-promoted, N-centered radical pathway involving a N,N-diiodosulfonamide reactive species. This method of direct N-incorporation offers an attractive alternative to the production of α-tertiary amines, a synthetically challenging structural class found in a variety of bioactive mols.

Organic & Biomolecular Chemistry published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Application of 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Tong published the artcilepH-controlled reversible deep-eutectic solvent based enzyme system for simultaneous extraction and in-situ separation of isoflavones from Pueraria lobata, HPLC of Formula: 23616-79-7, the publication is Separation and Purification Technology (2022), 120992, database is CAplus.

In this study, we developed an efficient and green pH-controlled reversible deep-eutectic solvents (DESs) based enzyme system for efficient extraction, transformation and in-situ separation of natural products from herbs. As a case study, seven isoflavones in the root of Pueraria lobata were selected as target compounds A series of DESs were firstly prepared and the extraction efficiency for target compounds with or without cellulase catalysis was investigated. We found that [N4444][Cl]:ethylene glycol (1:2) with cellulase addition show the highest extraction efficiency for isoflavones. More importantly, the phase behavior of [N4444][Cl]:ethylene glycol (1:2) based cellulase system was found to be pH-controlled. When pH is 5.0, the system is a homogeneous single-phase system, which is conducive to the extraction of natural products. When pH is 6.4, the system changes from the single-phase to the heterogeneous two-phase, to realize the in-situ separation of the compounds Therefore, by adjusting the pH of the system, the in-situ separation of isoflavones was successfully realized with high recovery yields. The pH-controlled DESs based enzyme-assisted extraction system overcomes the incompatibility between enzyme catalysis and conventional organic solvent in extraction, which could efficiently extract seven isoflavones from Pueraria lobata root.

Separation and Purification Technology published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C7H6ClF3N2, HPLC of Formula: 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics