Tag: M.W=300-350

Sitnikov, Nikolay S. published the artcileDesign and Synthesis of New Protease-Triggered CO-Releasing Peptide-Metal-Complex Conjugates, Safety of 2-Chlorotrityl chloride, the publication is European Journal of Organic Chemistry (2019), 2019(40), 6830-6837, database is CAplus.

Aiming at the development of novel protease-triggered CO-releasing mols. (PT-CORMs) the authors designed oxycyclohexadiene-Fe(CO)₃ complexes, which are connected through a self-immolative linker with a plasmin-specifying peptide unit. The challenging synthesis of these compounds was elaborated employing a combination of solid-phase peptide synthesis and solution chem. synthesis. Late-stage attachment of the organometallic unit and Pd-catalyzed cleavage of an alloc-protected lysine side chain afforded the target compounds in good yields and high purity.

European Journal of Organic Chemistry published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C25H23NO4, Safety of 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Dong, Huan published the artcileSynthesis and properties of tetraphenylethylene derivatived diarylethene with photochromism and aggregation-induced emission, HPLC of Formula: 219537-97-0, the publication is Dyes and Pigments (2017), 118-128, database is CAplus.

A series of new diarylethene compounds with both photochromism and aggregation-induced emission have been synthesized by connecting tetraphenylethene and triphenylethene to the bisthienylethene. All the four compounds exhibit good photochromism upon irradiation with alternative UV and visible light. And they are all provided with aggregation-induced emission properties in THF solution with different fraction of water, non-emissive in the pure THF solution but yellowish green fluorescence in the aggregate or solid state. Furthermore, the compounds connecting tetraphenylethene to the bisthienylethene were found to exhibit the stronger fluorescence emission in the aggregate or solid state than the ones connecting triphenylethene to the bisthienylethene.

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, HPLC of Formula: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Huaimin published the artcileEnzyme-Catalyzed Formation of Supramolecular Hydrogels as Promising Vaccine Adjuvants, Application In Synthesis of 42074-68-0, the publication is Advanced Functional Materials (2016), 26(11), 1822-1829, database is CAplus.

Promising vaccine adjuvants of self-assembling peptide hydrogels for protein ovalbumin (OVA) are introduced in this study. The hydrogels are formed by the enzyme of phosphatase, and the vaccine adjuvant potency of both L– and D-peptide hydrogels is evaluated. The results indicate that, compared with the clin. used alum adjuvant, both L– and D-peptide hydrogels can increase the IgG production of OVA for about 1.3 and 3.8 times, resp. Both gels can enhance antigen uptake and induce dendritic cell maturation, and promote and prolong accumulation of antigen in lymph node, as well as evoke germinal center formation. However, the D-peptide hydrogel with OVA exhibits a slightly more efficient accumulation of OVA in the lymph nodes and seems preventing tumor growth more significantly than its L-counterpart. With the good biocompatibility and degradability of peptide hydrogels, the hydrogels described in this study have big potential for the production of protein vaccines for immunotherapy against different diseases.

Advanced Functional Materials published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C12H15ClO3, Application In Synthesis of 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yu, Fei published the artcilePhotostimulus-Responsive Large-Area Two-Dimensional Covalent Organic Framework Films, Quality Control of 219537-97-0, the publication is Angewandte Chemie, International Edition (2019), 58(45), 16101-16104, database is CAplus and MEDLINE.

Using an external stimulus to modulate the electronic structure of covalent organic frameworks (COFs) is very important because such a response will endow them with addnl. functions. A two-dimensional (2D) COF, constructed from a photo-responsive unit (1,2-bis(5-formyl-2-methylthien-3-yl)cyclopentene), can reversibly switch its elec. conductivity 200 times from low state (the open form) to high state (the closed form) upon irradiation with UV light and reversible with visible light. This reversible phenomenon can be monitored through a circuit containing a light-emitting diode (LED). Photoinduced ring-closing/opening reactions do not destroy the integrity of the frameworks, and both processes follow logarithmic carrier generation with time. Moreover, the correlation between COFs electronic properties and changes in photoinduced kinetics and absorption curves has been demonstrated.

Angewandte Chemie, International Edition published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C3H8N2S, Quality Control of 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yang, Shuqing published the artcileOligomerization of isobutene catalyzed by AlCl₃ ionic liquids, HPLC of Formula: 23616-79-7, the publication is Shiyou Lianzhi Yu Huagong (2012), 43(5), 14-18, database is CAplus.

AlCl₃ ionic liquids having various cations and anions were synthesized. Tests for oligomerization of isobutene catalyzed by various AlCl₃ ionic liquids were conducted in an autoclave, and the effect of reaction temperature, reaction time and stirring speed was studied. Exptl. results indicated that these AlCl₃ ionic liquids exhibited good catalytic performance in isobutene oligomerization with conversion of isobutene over 95%. For ionic liquids synthesized by AlCl₃ and (C₂H₅)₃NHCl, when the mole ratio of AlCl₃ to(C₂H₅)₃NHCl was below 1, the AlCl₃ ionic liquid was inactive to isobutene oligomerization. When the mole ratio of AlCl₃ to(C₂H₅)₃NHCl was 1, the ionic liquid exhibited certain catalytic activity and its selectivity to dimers and trimers was good. When the mole ratio of AlCl₃ to (C₂H₅)₃NHCl was above 1, these ionic liquids could effectively catalyze oligomerization reactions, the conversion of isobutene reached more than 95%, yet the selectivity to dimers and trimers declined and the product distributions were continuous with certain amount of cracking byproducts. The optimal reaction conditions were as follows: a reaction temperature of 80°C, a reaction time of 30 min and stirring speed of 1300 r/min.

Shiyou Lianzhi Yu Huagong published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C9H7NO3, HPLC of Formula: 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yang, Shuqing published the artcileIsobutene oligomerization in ionic liquid, Application of N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Shiyou Lianzhi Yu Huagong (2007), 38(1), 39-42, database is CAplus.

Ionic liquid containing various anions or cations was synthesized. The catalytic performance and related reaction conditions of the oligomerization of isobutene catalyzed by ionic liquid were investigated in an autoclave. The exptl. results indicated that ionic liquid synthesized by anhydrous FeCl₃ and triethylamine hydrochloride could effectively catalyze oligomerization and had higher selectivity. The type of anion had important influence on activity and selectivity of the products, and the structure of cation also had important influence on activity. The test result showed that the product was the mixture of dimer, trimer, tetramer and pentamer without crackate. Under the reaction conditions of temperature 40 °C, reaction time 30 min, ionic liquid to olefin ratio 1.2 with 200 mL n-hexane as diluent, the conversion of isobutene reached 85%, and the concentration of dimer and trimer in oligomer was 22.87% and 57.43% resp.

Shiyou Lianzhi Yu Huagong published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C18H28B2O4, Application of N-Benzyl-N,N-dibutylbutan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Huang, Wenxiu published the artcileFunctional polyimides based on diamine containing diarylethylene moieties and their photochromic mechanism studies, SDS of cas: 219537-97-0, the publication is Polymer Chemistry (2020), 11(41), 6701-6707, database is CAplus.

To expand the existing application conditions of photochromic polymers and enhance the tolerance of photochromic polymer electronic devices in extreme environments, a diamine monomer DTEDA bearing the diarylethylene (DTE) moiety was synthesized and polymerized with com. available dihydrides to afford three polyimides (PIs, named DTEODPI, DTE6FPI and DTEHPMPI) through chem. imidization. These PIs realized reversible photo-triggered isomerization both in solution and in film state, with solution photoluminescence “on/off” effects. Semi-aromatic DTEHPMPI showed the largest contrast of color and fastest light response due to its local excited (LE) state. This research provides a simple method to prepare photochromic polymer materials with excellent comprehensive properties.

Polymer Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, SDS of cas: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Jin, Piaopiao published the artcileBinding porphyrins gated dithienylethene bridge, Formula: C15H14Cl2S2, the publication is Dyes and Pigments (2016), 151-158, database is CAplus.

Porphyrins strapped with photochromic dithienylethene have been prepared for photochem. double-throw gated switch. The strapped porphyrins performed totally different but reversible binding capacity and fluorescence intensity when irradiated by different lights. The photochromism of the dithienylethene bridge was effectively gated by porphyrin ring through binding or unbinding Zn²⁺. The central Zn²⁺ in the porphyrin ring was employed as a lock, external H⁺ as a key, which can alternately turn on/off the photochromic switch of the dithienylethene bridge. The porphyrins’ gate for binding/unbinding Zn²⁺ was reversibly regulated by dithienylethene switch with different irradiation lights. These distinctive properties might be utilized to multi-controlled mol. switches or logic gates.

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Formula: C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Luo, Qianfu published the artcileSynthesis and characteristics of dithienylethenes with purine and pyrimidine substituents, Application of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Dyes and Pigments (2015), 602-608, database is CAplus.

Five new dithienylethenes decorated with purine and pyrimidine derivatives have been conveniently synthesized via a facile one-pot process. All new compounds were characterized by ¹H NMR, ¹³C NMR, UV-visible spectroscopy and high-resolution mass spectrometry. Their photophys. properties and photochromic behavior were investigated in detail. These compounds exhibit reversible photochromism with good photocyclization/photocycloreversion quantum yields and considerable molar extinction coefficients The result shows that the introduction of purine and pyrimidine derivatives into the dithienylethene unit has a remarkable effect on their performance, such as photoinduced fatigue resistance, photocyclization/photocycloreversion quantum yields and molar extinction coefficient

Dyes and Pigments published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Application of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Jin published the artcileFolic Acid-Conjugated Pyropheophorbide a as the Photosensitizer Tested for In Vivo Targeted Photodynamic Therapy, Recommanded Product: 2-Chlorotrityl chloride, the publication is Journal of Pharmaceutical Sciences (2017), 106(6), 1482-1489, database is CAplus and MEDLINE.

Photodynamic therapy (PDT) is a highly localized and minimally invasive cancer treatment modality with many important advantages, but the lack of ideal photosensitizers (PSs) greatly restricts its clin. utility. To develop new PSs with highly efficient singlet oxygen production and high tumor-localizing ability to reduce damage to healthy adjacent tissues, we conjugated folic acid (FA) with pyropheophorbide a (Pyro), a potent PS with a very high singlet oxygen quantum yield and a high extinction coefficient In the present work, we describe the synthesis and PDT evaluation of this FA-Pyro conjugate both in vitro and in vivo. This conjugation increased the accumulation of Pyro inside the tumors and improved the efficiency of PDT, resulting in eradication of s.c. xenograft KB (human mouth epidermal carcinoma) tumors after only 1 or 2 applications of external near IR light irradiation This outstanding PDT outcome in a tumor-bearing mouse model and the simple synthesis of the conjugate should have very good practical potential for clin. application.

Journal of Pharmaceutical Sciences published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C8H14O2, Recommanded Product: 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics