Tag: M.W=300-350

Kemper, Jerome M. published the artcileQuaternary Amines As Nitrosamine Precursors: A Role for Consumer Products?, Related Products of chlorides-buliding-blocks, the publication is Environmental Science & Technology (2010), 44(4), 1224-1231, database is CAplus and MEDLINE.

Nitrosamine formation has been associated with wastewater-impacted waters, but specific precursors within wastewater effluents have not been identified. Experiments indicated that nitrosamines form in low yields from quaternary amines, and that the nitrosamines form from the quaternary amines themselves, not just lower order amine impurities. Polymeric and benzylated quaternary amines were more potent precursors than monomeric quaternary alkylamines. Pretreatment of quaternary amines with ozone or free Cl, which deactivate lower order amine impurities, did not significantly reduce nitrosamine formation. The nitrosamine formation pathway is unclear but experiments indicated that transformation of quaternary amines to lower order amine precursors via Hofmann elimination was not involved. Experiments suggest that the pathway may involve quaternary amine degradation by amidogen or chloramino radicals formed from chloramines. Quaternary amines are significant constituents of consumer products, including shampoos, detergents, and fabric softeners. Although quaternary amines may be removed by sedimentation during wastewater treatment, their importance should be evaluated on a case-by-case basis. The high loadings from consumer products may enable the portion not removed to serve as precursors.

Environmental Science & Technology published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Sheng published the artcilePhoto-induced morphology transition of a multifunctional photochromic bisthienylethene molecule with switchable aggregation-induced emission, HPLC of Formula: 219537-97-0, the publication is Science China: Chemistry (2018), 61(10), 1301-1306, database is CAplus.

A novel multifunctional mol. BTE-CNPH was designed and synthesized by connecting 2-(3�5�bis(trifluoromethyl)-biphenyl-4-yl)-2-cyanovinyl group to both side of the bisthienylethene (BTE), which exhibited excellent aggregation-induced emission (AIE) and bistable photochromism. High-contrast (>60) reversible fluorescence switching was achieved in the 1D nanowires, solid of BTE-CNPH and also in a polymethyl methacrylate (PMMA) film loaded with 1% BTE-CNPH under the alternative irradiation by 365 nm and visible light. Interestingly, the nanowire-like assembly morphol. of BTE-CNPH in aqueous THF (THF) solution of specific concentration was observed to translate into amorphous pieces gradually upon prolonged irradiation by the 365 nm, accompanying with photo-tunable AIE emission.

Science China: Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C12H15ClO3, HPLC of Formula: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Seibold, Uwe published the artcileRational Design, Development, and Stability Assessment of a Macrocyclic Four-Hydroxamate-Bearing Bifunctional Chelating Agent for ⁸⁹Zr, Product Details of C19H14Cl2, the publication is ChemMedChem (2017), 12(18), 1555-1571, database is CAplus and MEDLINE.

Zirconium-89 is a positron-emitting radionuclide of high interest for medical imaging applications with positron emission tomog. (PET). For the introduction of this radiometal into biol. active targeting vectors, the chelating agent desferrioxamine B (DFO) is commonly applied. However, DFO is known to form ⁸⁹Zr complexes of limited in vivo stability. Herein we describe the rational design and chem. development of a new macrocyclic four-hydroxamate-bearing chelating agent-1,10,19,28-tetrahydroxy-1,5,10,14,19,23,28,32-octaazacyclohexatriacontan-2,6,11,15,20,24,29,33-octaone (CTH36)-for the stable complexation of Zr⁴⁺. For this purpose, we first performed computational studies to determine the optimal chelator geometry before we developed different synthesis pathways toward the target structures. The best results were obtained using an efficient solution-phase-based synthesis strategy toward the target chelating agent. To enable efficient and chemoselective conjugation to biomols., a tetrazine-modified variant of CTH36 was also developed. The excellent conjugation characteristics of the so-functionalized chelator were demonstrated on the example of the model peptide TCO-c(RGDfK). We determined the optimal ⁸⁹Zr radiolabeling parameters for CTH36 as well as its bioconjugate, and found that ⁸⁹Zr radiolabeling proceeds efficiently under very mild reaction conditions. Finally, we performed comparative complex stability tests for ⁸⁹Zr-CHT36-c(RGDfK) and ⁸⁹Zr-DFO-c(RGDfK), showing improved complex stability for the newly developed chelator CTH36.

ChemMedChem published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C8H7NO4, Product Details of C19H14Cl2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yao, Shengxin published the artcileSynthesis and spectroscopic properties of BODIPY-dithienylethene conjugates, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of Porphyrins and Phthalocyanines (2021), 25(10/12), 930-936, database is CAplus.

Two red fluorescent triads containing photochromic dithienylethene moiety linked to two 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) via acetylene bond, 1a or single bond, 1b were synthesized and characterized. Although no evident absorption and NMR spectra changes were observed upon irradiation with visible light, the absorption and fluorescence spectra of 1a and 1b are remarkably solvent dependent, in contrast to those of the reference BODIPY-thienyl compounds 2a and 2b, which are essentially solvent independent. Fluorescence intensities of 1a and 1b decreased as the solvent polarity increased, and the fluorescence decay showed two exponentials in polar solvents other than n-hexane. DFT calculations have been carried out to elucidate the spectral behavior of investigated compounds

Journal of Porphyrins and Phthalocyanines published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C14H14, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mohamed, Heba A. published the artcileSilver(I) N-Heterocyclic Carbene Complexes Derived from Clotrimazole: Antiproliferative Activity and Interaction with an Artificial Membrane-Based Biosensor, Formula: C19H14Cl2, the publication is Organometallics (2020), 39(8), 1318-1331, database is CAplus.

With the aim of combining the potential anticancer properties of both clotrimazole, an imidazole based antifungal agent, and Ag(I) N-heterocyclic carbenes, 13 novel Ag(I) N-heterocyclic carbene complexes derived from clotrimazole were synthesized. The complexes were fully characterized, and the partition coefficient of each provides a measure of hydrophobicity. The antiproliferative properties of the complexes against cancerous and noncancerous cell lines found optimum cytotoxicity when the complex displays an intermediate lipophilicity, which describes a complex that possesses both water-soluble groups and lipophilic aromatic groups. The Ag complexes were screened on a synthetic biomembrane-like device using a chip-based phospholipid-coated Pt/Hg electrode embedded in a flow cell system. The results are recorded as rapid cyclic voltammograms (RCVs), which give insight into the interactions of the complexes with a cell membrane. The principle of intermediate lipophilicity also applies to the monolayer interaction to which the Ag atom significantly implements an irreversibility.

Organometallics published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Formula: C19H14Cl2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yuan, Dan published the artcileThe enzyme-instructed assembly of the core of yeast prion Sup35 to form supramolecular hydrogels, Name: 2-Chlorotrityl chloride, the publication is Journal of Materials Chemistry B: Materials for Biology and Medicine (2016), 4(7), 1318-1323, database is CAplus and MEDLINE.

Based on the self-assembly capability of the core segment (GNNQQNY) of yeast prion Sup35, we design and synthesize a series of structurally related precursors for the enzymic formation of hydrogels. We found that, with the catalysis of alk. phosphatase, the precursor becomes a hydrogelator that self-assembles in water to form nanofibers with an average width less than ten nanometers. Interestingly, the introduction of an amyloid segment into a cytotoxic precursor (N’ffyp: D-1P) is able to abrogate the cytotoxicity of the precursor, making the resulting peptide cell compatible. This work contributes a new insight into the use of enzymes to form cell compatible hydrogels of peptide cross-β spine.

Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C17H18N2O6, Name: 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hirabayashi, Ayumi published the artcilePhotodegradation of amyloid β and reduction of its cytotoxicity to PC12 cells using porphyrin derivatives, Recommanded Product: 2-Chlorotrityl chloride, the publication is Chemical Communications (Cambridge, United Kingdom) (2014), 50(67), 9543-9546, database is CAplus and MEDLINE.

A purpose-designed porphyrin-peptide hybrid effectively degraded amyloid β monomer and oligomers associated with Alzheimer’s disease. Degradation was achieved using light irradiation in the absence of any additives and under neutral conditions. Moreover, the hybrid effectively neutralized the cytotoxicity of amyloid β in PC12 cells upon photoirradiation

Chemical Communications (Cambridge, United Kingdom) published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, Recommanded Product: 2-Chlorotrityl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ge, Dandan published the artcilePreparation of new hydrophobic deep eutectic solvents and their application in dispersive liquid-liquid microextraction of Sudan dyes from food samples, Category: chlorides-buliding-blocks, the publication is Analytical and Bioanalytical Chemistry (2021), 413(15), 3873-3880, database is CAplus and MEDLINE.

In this work, a new generation of hydrophobic deep eutectic solvents (DESs) was prepared using eugenol (as hydrogen bond donor) and benzyltriethylammonium bromide, benzyltributylammonium bromide, benzyltriethylammonium chloride and benzyltributylammonium chloride (as hydrogen bond acceptor) in different molar ratios. These DESs were applied to vortex-assisted dispersive liquid-liquid microextraction of Sudan dyes from food samples, followed by high-performance liquid chromatog. determination The influencing parameters, including the type of DES, amount of DES, extraction time, solution pH and salt addition, were investigated and optimized. Under the optimized conditions, a linear range of 2-1000 ng mL-1 with determination coefficients of <0.999 was obtained. Limits of detection and limits of quantification were in the range of 0.5 to 1 ng mL-1 and 2 to 3 ng mL-1, resp. The proposed method was successfully used in the determination of Sudan dyes in chili sauce, chili powder and ketchup, and satisfactory recoveries of between 89.9 and 119.3% were obtained, with relative standard deviations in the range of 0.1-6.8%. The proposed method is simple, green and efficient, and can be applied to determine Sudan dyes in complex matrixes.

Analytical and Bioanalytical Chemistry published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Cui, Shuzhen published the artcileSynthesis and characterisation of photochromic dithienylcyclopentene liquid crystal with thermal irreversibility, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Liquid Crystals (2016), 43(6), 803-810, database is CAplus.

A series of photochromic liquid crystal dithienylcyclopentene derivatives I (n = 4, 5, 6, 7) was synthesized from the initial material 2-chloro-5-methylthiophene. They were characterized by ¹H NMR, high resolution mass spectrometer, differential scanning calorimetry (DSC) and polarized optical microscopy (POM) with a hot stage. All of them exhibited excellent photochem. reversible isomerization between the open-ring form and the closed-ring form in both organic solvents and LC media, resulting in the color change between colorless and purple under different light irradiations. The typical textures from POM showed that their isomers both had nematic phase and smectic phase with different colors. These compounds with bent shape were more sensitive to light than those of diarylethenes reported.

Liquid Crystals published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Feng, Yanli published the artcileNew photochromic bisthienylethene derivatives containing carbazole, SDS of cas: 219537-97-0, the publication is Journal of Physical Organic Chemistry (2007), 20(11), 968-974, database is CAplus.

Some new photochromic bisthienylethene (BTE) derivatives containing carbazole were synthesized by Suzuki coupling method. All compounds were characterized by ¹H NMR spectra, ¹³C NMR, mass spectra, etc. Their optical, photochromic, and electrochem. properties were described. Moreover, their two-photon absorption (TPA) properties were investigated both in open and closed forms, finding observable distinction in the TPA of the ring-open and ring-closed forms. These compounds could be used as two-photon switches and for the potential applications in three-dimensional optical storage.

Journal of Physical Organic Chemistry published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, SDS of cas: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics