Tag: M.W=250-300

Gao, Wa; Wang, Lu; Gao, Chao; Liu, Jinqiu; Yang, Yong; Yang, Liuqing; Shen, Qing; Wu, Congping; Zhou, Yong; Zou, Zhigang published the artcile< Exquisite design of porous carbon microtubule-scaffolding hierarchical In2O3-ZnIn2S4 heterostructures toward efficient photocatalytic conversion of CO2 into CO>, Product Details of Cl3H8InO4, the main research area is carbon dioxide indium oxide zinc sulfur semiconductor heterostructure.

Porous carbon microtubule (PCMT)-scaffolding semiconductor heterostructures were exquisitely designed through the in situ growth of ZnIn2S4 (ZIS) ultrathin nanosheets onto In2O3 nanoparticle layers generated on the surface PCMT (abbreviated as PCMT@In2O3/ZIS) toward the efficient photocatalytic conversion of CO2 into CO. The pronounced photocatalytic performance for CO2 photoreduction into CO is attributed to a synergistic effect of the following factors: (1) the multistage hopping of the charge carriers among In2O3, ZIS, and PCMT greatly reduces the charge recombination in In2O3 and ZIS. An (2) The mesoporous feature of the PCMT renders the large surface area and abundant active sites to accumulate the local concentration of CO2 in the heterostructures. An (3) The existence of a large amount of carbon defects in PCMT promotes the activity of the absorbed CO2 mols. An (4) The tubular structures with two open ends of PCMT may favor the fast diffusion of the reactants and products, and the optical absorption can also be increased by multi-light scattering/reflection in the interior void. An (5) The unique fabrication route leads to an intimate and tight contact among PCMT, In2O3, and ZIS, which is also favorable for the charge migration. This work makes a contribution to the development of a complex hollow photocatalysis system for artificial photosynthesis.

Nanoscale published new progress about Band gap. 22519-64-8 belongs to class chlorides-buliding-blocks, and the molecular formula is Cl3H8InO4, Product Details of Cl3H8InO4.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Byun, Youngjoo; Vogel, Susan R.; Phipps, Andrew J.; Carnrot, Cecilia; Eriksson, Staffan; Tiwari, Rohit; Tjarks, Werner published the artcile< Synthesis and Biological Evaluation of Inhibitors of Thymidine Monophosphate Kinase from Bacillus anthracis>, Application of C7H7ClO4S2, the main research area is thymidine phosphate analog preparation inhibitor Bacillus thymidine monophosphate kinase.

Nineteen lipophilic thymidine phosphate-mimicking compounds were designed and synthesized as potential inhibitors of thymidine monophosphate kinase of Bacillus anthracis, a Gram-pos. bacterium that causes anthrax. These thymidine analogs were substituted at the 5′-position with sulfonamide-, amide-, (thio)urea-, or triazole groups, which served as lipophilic surrogates for phosphate. Three of the tested compounds produced inhibition of B. anthracis growth and/or thymidine monophosphate activity. Addnl. studies will be necessary to elucidate the potential of this type of B. anthracis thymidine monophosphate inhibitors as novel antibiotics in the treatment of anthrax.

Nucleosides, Nucleotides & Nucleic Acids published new progress about Anthrax (disease). 5335-40-0 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H7ClO4S2, Application of C7H7ClO4S2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wu, Kai; Jiang, Renqian; Zhao, Yulong; Mao, Liang; Gu, Xiuquan; Cai, Xiaoyan; Zhu, Mingshan published the artcile< Hierarchical NiCo2S4/ZnIn2S4 heterostructured prisms: High-efficient photocatalysts for hydrogen production under visible-light>, Product Details of Cl3H8InO4, the main research area is nickel cobalt zinc indium sulfide heterostructured prisms; zinc indium sulfide hydrogen production photocatalysts visible light; Charge separation; Co-catalyst; Hollow structure; Hydrogen; Photocatalyst.

Exploring low-cost co-catalyst to ameliorate the photocatalytic activity of semiconductors sets a clear direction for solving energy crisis and achieving efficient solar-chem. energy conversion. In this work, a unique hierarchical hollow heterojunction was constructed by in-situ growing ZnIn2S4 nanosheets on the porous NiCo2S4 hollow prisms through a low temperature solvothermal method, in which NiCo2S4 with semi-metal property acted as non-noble metal co-catalyst. NiCo2S4 co-catalyst was innovatively encapsulated in ZnIn2S4, which not only relieved the light shielding effect caused by the large loading amount of co-catalyst, but also supplied abundant active sites for H2 evolution. The hierarchical hollow heterostructure of NiCo2S4 /ZnIn2S4 provided a highly efficient channel for charge transfer. Combining these advantages, NiCo2S4 /ZnIn2S4 composite demonstrated excellent photocatalytic activity. In the absence of sacrificial agent, the NiCo2S4/ZnIn2S4 photocatalyst achieved a remarkable improved H2 yield of 0.77 mmol g-1h-1 under visible light irradiation (λ > 400 nm), which is 6.6 times greater than that of ZnIn2S4. Besides, NiCo2S4 even exhibited better performance on the H2 evolution improvement of ZnIn2S4 than precious metal Pt. This work will offer novel insights into the reasonable design of non-noble metal photocatalysts with respectable activity for water splitting.

Journal of Colloid and Interface Science published new progress about Centrifugation. 22519-64-8 belongs to class chlorides-buliding-blocks, and the molecular formula is Cl3H8InO4, Product Details of Cl3H8InO4.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Mukherjee, N.; Delay, E. R. published the artcile< Cyclophosphamide-induced disruption of umami taste functions and taste epithelium>, COA of Formula: C7H17Cl2N2O3P, the main research area is cyclophosphamide monohydrate taste bud epithelium monosodium glutamate IMP.

Clin. studies have reported taste dysfunctions developing in patients undergoing chemotherapy. This adverse side effect is a major concern for the doctors and patients because disrupted taste can reduce appetite, cause malnutrition, delay recovery, and affect quality of life. Cyclophosphamide (CYP) is a common atenoplastic drug used during chemotherapy and is thought to affect taste through learned tasted aversions. This study asked whether CYP also alters umami taste sensory functions and disrupts taste epithelium of mice. Behavioral tests focused on taste acuity, assessed by the ability of mice to discriminate between the taste qualities of two umami substances, monosodium glutamate (MSG) and IMP, and taste sensitivity, assessed by detection thresholds of MSG and IMP, after an IP injection (75 mg/kg) of CYP. The behavioral results revealed a two-phase disturbance in taste acuity and loss of sensitivity, the first phase occurring within 2-4 days after injection and the second occurring 9-12 days after injection. The number of fungiform papillae (with and without pores) decreased immediately after injection and did not begin to recover until 12 days after injection. Circumvallate taste buds began to show disturbances by 8 days after injection and evidence of recovery beginning 12 days after injection. Von Ebner glands were smaller and secreted less saliva 4 days postinjection but not later. These findings suggest the initial behavioral deficits may be because of cytotoxic effects of the drug on taste sensory tissues, whereas the second phase may be because of a disturbance of the taste cell replacement cycle.

Neuroscience (Amsterdam, Netherlands) published new progress about Body weight. 6055-19-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H17Cl2N2O3P, COA of Formula: C7H17Cl2N2O3P.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Huang, X.; Chen, X. L.; Zheng, Z. W.; Ji, H. M.; Ma, Y. L. published the artcile< Dense chalcopyrite CuInSe2 thin films prepared with ethanol-based In2Se3-Cu+ ink>, Computed Properties of 22519-64-8, the main research area is chalcopyrite copper indium diselenide thin film ethanol ink.

Here, we show a novel ink containing ethanol, In2Se3 nanosheets and Cu+ that can be used as the sol for filming by dip coating method. And pure chalcopyrite (CH) CuInSe2 (CIS) thin films were obtained when In2Se3 nanosheets with poor crystallinity as a component of the ink. We described the formation of the CH CIS films that exhibit (112)-orientation and dense structure without interspace. Hall measurement shows that the CIS film sintered at 550°C has an elec. resistivity of 3.19 Ω·cm and carrier concentration of 2.63×1017 cm-3, which meet the requirements of high performance solar cell absorption layer.

Chalcogenide Letters published new progress about Absorption. 22519-64-8 belongs to class chlorides-buliding-blocks, and the molecular formula is Cl3H8InO4, Computed Properties of 22519-64-8.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Hakura, Atsushi; Hori, Yuji; Uchida, Kanako; Sawada, Shigeki; Suganuma, Akiyoshi; Aoki, Toyohiko; Tsukidate, Kazuo published the artcile< Inhibitory effect of dimethyl sulfoxide on the mutagenicity of promutagens in the Ames test>, Name: 2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate, the main research area is dimethyl sulfoxide promutagen mutagenicity inhibition detoxification.

The effect of DMSO on the mutagenicity of 14 promutagens belonging to several chem. classes and one direct mutagen as a reference compound was examined in the Ames preincubation test, to clarify how much the test results were affected by its inhibitory activity on metabolic enzymes. The mutagens were assayed by the preincubation method using the TA100 or WP2uvrA (pKM101) bacterial test strains in the presence of 1% and 14% DMSO (concentrations in treatment mixture) with S9 mix for 12 promutagens that are known to be activated by CYP enzymes or without S9 mix for 2 promutagens that are known to be activated by bacterial nitroreductase enzymes, and the direct-mutagen. The data indicate that the mutagenicity of 11 of the 14 promutagens was significantly reduced in the presence of 14% DMSO as compared with that in the presence of 1% DMSO, while the 3 remaining promutagens and the direct mutagen exhibited mutagenicity of equal degree at both concentrations The largest inhibitory effect of DMSO was found on the nitrosamines in WP2uvrA(pKM101) and TA100, and no cytotoxicity was detected by survival test, with 14% DMSO in WP2uvrA(pKM101), at any amounts of dimethylnitrosamine. Further equivalent or slightly lower cytotoxicity in the presence of 14% DMSO than in the presence of 1% DMSO was detected by decrease in the bacterial background-lawn d., as a whole. These observations suggest that the reduction in the yield of revertant colonies in the presence of 14% DMSO with the 11 chems. was not due to cytotoxicity of DMSO. The inhibitory effect of DMSO on the mutagenicity of the promutagens can be explained by its inhibitory effect on the drug-metabolizing enzymes involved in the activation/detoxification pathways. Use of DMSO at a low concentration, such as 1%, may be suggested for the Ames test, as for other in vitro genotoxicity tests.

Genes and Environment published new progress about Biological detoxification. 6055-19-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H17Cl2N2O3P, Name: 2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ngo, Le P.; Owiti, Norah A.; Swartz, Carol; Winters, John; Su, Yang; Ge, Jing; Xiong, Aoli; Han, Jongyoon; Recio, Leslie; Samson, Leona D.; Engelward, Bevin P. published the artcile< Sensitive CometChip assay for screening potentially carcinogenic DNA adducts by trapping DNA repair intermediates>, Related Products of 6055-19-2, the main research area is DNA adduct trapping repair CometChip screening environment carcinogen.

Genotoxicity testing is critical for predicting adverse effects of pharmaceutical, industrial, and environmental chems. The alk. comet assay is an established method for detecting DNA strand breaks, however, the assay does not detect potentially carcinogenic bulky adducts that can arise when metabolic enzymes convert pro-carcinogens into a highly DNA reactive products. To overcome this, we use DNA synthesis inhibitors (hydroxyurea and 1-β-D-arabinofuranosyl cytosine) to trap single strand breaks that are formed during nucleotide excision repair, which primarily removes bulky lesions. In this way, comet-undetectable bulky lesions are converted into comet-detectable single strand breaks. Moreover, we use HepaRG cells to recapitulate in vivo metabolic capacity, and leverage the CometChip platform (a higher throughput more sensitive comet assay) to create the ‘HepaCometChip’, enabling the detection of bulky genotoxic lesions that are missed by current genotoxicity screens. The HepaCometChip thus provides a broadly effective approach for detection of bulky DNA adducts.

Nucleic Acids Research published new progress about Alkaline comet assay. 6055-19-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H17Cl2N2O3P, Related Products of 6055-19-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Clardy, J. C.; Mosbo, J. A.; Verkade, J. G. published the artcile< Crystal and molecular structure of cyclophosphamide hydrate>, Formula: C7H17Cl2N2O3P, the main research area is phosphamide cyclo crystal structure; carcinostatic cyclophosphamide crystal structure.

The x-ray structure of the cyclophosphamide (I) showed that the chair-form ring possesses an equatorial dialkyl amino group and an axial phosphoryl O. The triclinic crystals, space group P1,̅ had a 8.65, b 13.39, c 6.01 Å, α 96.3, β 100.3, and γ 106.7.degree., and Z = 2. The structure was refined by least-squares to R = 7.2% for 1601 reflections.

Journal of the Chemical Society, Chemical Communications published new progress about Crystal structure. 6055-19-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H17Cl2N2O3P, Formula: C7H17Cl2N2O3P.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Li, Yi; Yu, Shan; Doronkin, Dmitry E.; Wei, Shiqian; Dan, Meng; Wu, Fan; Ye, Liqun; Grunwaldt, Jan-Dierk; Zhou, Ying published the artcile< Highly dispersed PdS preferably anchored on In2S3 of MnS/In2S3 composite for effective and stable hydrogen production from H2S>, Product Details of Cl3H8InO4, the main research area is manganese indium palladium sulfide photocatalytic hydrogen evolution.

As an important byproduct during natural gas exploitation, green utilization of hydrogen sulfide (H2S) by photocatalysis has offered us the possibility for production of clean hydrogen (H2) from H2S with low energy consumption. In this work, we have successfully introduced well-dispersed palladium sulfide (PdS) which is preferably loaded on In2S3 of MnS/In2S3 composite for improved photocatalytic hydrogen evolution from H2S aqueous solution In contrast to binary MnS/In2S3, ternary MnS/In2S3/PdS has exhibited a remarkable and stable hydrogen production rate of 22.7 mmol g-1 h-1 with an apparent quantum yield of 34% at around 395 nm. A comprehensive structure characterization of the ternary composite including scanning transmission electron microscopy (STEM) and X-ray absorption spectroscopy (XAS) in combination with theor. calculations confirm the good dispersion of PdS in the composite. Moreover, we discovered that PdS preferably interact with In2S3 rather than MnS in the composite through Pd-S-In bond on the interface of the two. Photoluminescence (PL) spectra, surface photovoltage (SPV) spectra together with transient photocurrent and electrochem. impedance spectra (EIS) demonstrate the advantage of PdS for promoting the charge separation This work sheds light on the pos. effect on the enhanced activity of the corresponding system resulting from the preferable anchoring of highly dispersed PdS on In2S3 in the composite by chem. Pd-S-In bond. Not only the high dispersion but also the preferable anchoring of the co-catalyst in the composite could hence inspire people for more rational designs of ternary composite in future.

Journal of Catalysis published new progress about Band structure. 22519-64-8 belongs to class chlorides-buliding-blocks, and the molecular formula is Cl3H8InO4, Product Details of Cl3H8InO4.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Hirose, Orie; Itabashi, Mitsuyo; Takei, Takashi; Nitta, Kosaku published the artcile< Comparison of a novel chemiluminescence enzyme immunoassay (CLEIA) with enzyme-linked immunosorbent assay (ELISA) for the determination of MPO-ANCA in patients with ANCA-associated vasculitis>, Formula: C7H17Cl2N2O3P, the main research area is chemiluminescence enzyme immunoassay ELISA MPO ANCA human AAV; ANCA-associated vasculitis; BVAS; CLEIA; ELISA; MPO-ANCA.

Background. Myeloperoxidase (MPO) anti-neutrophil cytoplasmic antibody (ANCA) represents the serol. hallmark of ANCA-associated vasculitis (AAV). We evaluated the anal. and diagnostic accuracy of chemiluminescence enzyme immunoassay (CLEIA) vs. ELISA for the detection of MPO-ANCA. Methods. A total of 242 sera obtained from 51 patients with AAV and 103 patients without AAV were tested for MPO-ANCA by ELISA (NephroScholor MPOANC II) and CLEIA (the STACIA MEBLux test). Disease activity in the patients with AAV was determined based on the Birmingham Vasculitis Activity Score. We analyzed the correlations between the MPO-ANCA titers determined by the CLEIA and those determined by the ELISA, and also between the MPO-ANCA titers and the disease activity. Results. The MPO-ANCA titers determined by the CLEIA (x) were strongly correlated with those determined by the ELISA (y). The correlation could be expressed by the following equation in this study: y = 1.8x + 7.7 (r = 0.96; p < 0.0001). At the cutoff value of 3.5 U/mL, the CLEIA yielded pos. test results for MPO-ANCA in 73 of the 242 sera (30.2%), while at the cutoff value of 20 U/mL, ELISA yielded pos. test results in 57 of the 242 sera (23.6%). The CLEIA yielded false-pos. test results in 4 of the 120 sera obtained from the non-AAV patients (3.3%), whereas the ELISA yielded a false-pos. result in only 1 of the 120 sera obtained from the non-AAV patients (0.8%). The sensitivity and specificity of the CLEIA for the diagnosis of AAV were 100% and 96.7%, resp., while those of the ELISA were 94.3% and 99.2%, resp. The sensitivity and specificity of the CLEIA for the prediction of active disease were 100% and 64.4%, resp., while those of the ELISA were 94.3% and 73.6%, resp. Conclusion. The false positivity rate of the CLEIA for MPO-ANCA tended to be high as compared with that of the ELISA. Also, according to the correlation coefficient between the results of the CLEIA and the ELISA calculated in this study, it is necessary to pay attention to the differences in the sensitivity and specificity between CLEIA and ELISA. Modern Rheumatology published new progress about Blood analysis. 6055-19-2 belongs to class chlorides-buliding-blocks, and the molecular formula is C7H17Cl2N2O3P, Formula: C7H17Cl2N2O3P.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics