Tag: M.W=250-300

He, Zhi-Tao published the artcileTrimethylphosphate as a Methylating Agent for Cross Coupling: A Slow-Release Mechanism for the Methylation of Arylboronic Esters, COA of Formula: C13H17BCl2O2, the publication is Journal of the American Chemical Society (2018), 140(49), 17197-17202, database is CAplus and MEDLINE.

Tri-Me phosphate acted as an effective source of Me groups; in the presence of CuI, and LiI, (MeO)₃P(:O) underwent chemoselective coupling with arylpinacolboronates mediated by LiOt-Bu in 1,3-dimethylimidazolidin-2-one (DMI) to yield methylarenes in higher yields than related coupling reactions using either Me iodide or Me tosylate. The methylation reaction was used in tandem with iridium-catalyzed regioselective borylation with bis(pinacolato)diboron to provide a one-pot methylation reaction for arenes, and for trideuteromethylation of arylpinacoboronates using tris(trideuteromethyl) phosphate. The chemoselectivity of the reaction was tested using additives possessing various functional groups (robustness screen); unprotected amines, alcs., and amides and terminal alkynes were not tolerated. The methylation of 1-naphthylpinacolboronate was demonstrated on a 200 mmol scale. The kinetics of the methylation and its dependence on Li⁺ and I^– ions was determined and a mechanism suggested. Me iodide is released slowly upon reaction of tri-Me phosphate with iodide; the low concentration of MeI enables selective reaction with arylcopper intermediates generated from the arylboronate rather than with other nucleophiles, while binding of tert-butoxide to the pinacolboronate reactants inhibits reaction of MeI with tert-butoxide.

Journal of the American Chemical Society published new progress about 942069-73-0. 942069-73-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronate Esters,Boronic Acids,Boronic acid and ester, name is 2-(3,5-Dichloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C13H17BCl2O2, COA of Formula: C13H17BCl2O2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Arthuis, Martin published the artcilePd⁰-Catalyzed carbonylation of 1,1-dichloro-1-alkenes, a new selective access to Z-α-chloroacrylates, HPLC of Formula: 866-23-9, the publication is Chemical Communications (Cambridge, United Kingdom) (2010), 46(41), 7810-7812, database is CAplus and MEDLINE.

A novel and fully chemo- and stereoselective three component strategy leading to Z-α-chloroacrylates by a Pd⁰-catalyzed reaction of CO (1 atm) with 1,1-dichloro-1-alkenes and various alcs. is disclosed. This catalytic approach compares favorably with the Wittig type strategies as α-chloroacrylates of pure Z configuration are obtained in high yield.

Chemical Communications (Cambridge, United Kingdom) published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, HPLC of Formula: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sedelmeier, Jorg published the artcileKMnO₄-Mediated Oxidation as a Continuous Flow Process, SDS of cas: 3919-74-2, the publication is Organic Letters (2010), 12(16), 3618-3621, database is CAplus and MEDLINE.

An efficient and easily scalable transformation of alcs. and aldehydes to carboxylic acids and nitroalkane derivatives to the corresponding carbonyls and carboxylic acids using permanganate as the oxidant within a continuous flow reactor is reported. Notably, the generation and downstream processing of MnO₂ slurries was not found to cause any blocking of the reactor when ultrasound pulses were applied to the flow system.

Organic Letters published new progress about 3919-74-2. 3919-74-2 belongs to chlorides-buliding-blocks, auxiliary class Isoxazole,Fluoride,Chloride,Carboxylic acid,Benzene, name is 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, and the molecular formula is C16H10O5, SDS of cas: 3919-74-2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Herbort, James H. published the artcileCationic Co(I) Catalysts for Regiodivergent Hydroalkenylation of 1,6-Enynes: An Uncommon cis-α-C-H Activation Leads to Z-Selective Coupling of Acrylates, Safety of Sodium chloro(tosyl)amide trihydrate, the publication is ACS Catalysis (2021), 11(15), 9605-9617, database is CAplus and MEDLINE.

Two intermol. hydroalkenylation reactions of 1,6-enynes N(R)(CH²CH=CH²)CH²CCR¹ (R = -N(Ts)-, -C(COOEt)₂-, -O-, -N(Boc)-; R¹ = 4-fluorophenyl, thiophen-3-yl, prop-1-en-2-yl, etc.) are presented which yield substituted 5-membered carbo- and -heterocycles I (R = -N(Ts)-, -C(COOEt)²-; R² = H, Me; R³ = H, Me, n-Bu). This reactivity is enabled by a cationic bis-diphenylphosphinopropane (DPPP)CoI species which forms a cobaltacyclopentene intermediate by oxidative cyclization of the enyne. This key species interacts with alkenes in distinct fashion, depending on the identity of the coupling partner to give regiodivergent products I. Simple alkenes undergo insertion reactions to furnish 1,3-dienes whereby one of the alkenes is tetrasubstituted. The acerylates R⁴CH=C(R⁵)C(O)OR⁶ (R⁴ = H, Me, OMe; R⁵ = H, Me; R⁶ = Me, Bn, Cy, t-Bu) were employed as coupling partners, and the site of intermol. C-C formation shifts from the alkyne to the alkene motif of the enyne, yielding Z-substituted-acrylate derivatives II. Computational studies provide support for the exptl. observations and show that the turnover-limiting steps in both reactions are the interactions of the alkenes with the cobaltacyclopentene intermediate via either a 1,2-insertion in the case of ethylene, or an unexpected α-C-H activation in the case of most acrylates. Thus, the H syn to the ester is activated through the coordination of the acrylate carbonyl to the cobaltacycle intermediate, which explains the uncommon Z-selectivity and regiodivergence. Variable time normalization anal. (VTNA) of the kinetic data reveals a dependence upon the concentration of cobalt, acrylate, and activator. A KIE of 2.1 was observed with Me methacrylate in sep. flask experiments, indicating that C-H cleavage is the turnover-limiting step in the catalytic cycle. Lastly, a Hammett study of aryl-substituted enynes yields a ρ value of -0.4, indicating that more electron-rich substituents accelerate the rate of the reaction.

ACS Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Safety of Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hunziker, F. published the artcileChemistry and pharmacology of dibenzo[b,e][1,4]diazepine derivatives with basic substituents in position 10, Quality Control of 60091-87-4, the publication is Arzneimittel-Forschung (1963), 324-8, database is CAplus and MEDLINE.

A series of I derivatives was prepared according to Clemo, et al. (CA 19, 293) and Burton and Gibson (CA 19, 987) by an Ullmann-synthesis from o-bromonitrobenzenes and free anthranilic acid derivatives in presence of K₂CO₃ and catalytic amounts of Cu in a higher alcohol as solvent. The N-methylated anthranilic acids gave lower yields (50-60%) than the corresponding primary amines. The esters of I were best obtained via the acid chlorides. Thus, the following I derivatives were prepared (R¹, R², R³, and m.p. given): H, 4-Me, H, 213-15°; H, 4-Me, Et, 99-100°; Me, 4-Me, H, 140-1°; H, 4-Cl, H, 245-8°; H, 4-Cl, Et, 134-6°; Me, 4-Cl, H, 139-42°; H, 4-CF₃, H, 225-6°; H, 4-CF₃, Me, 147-8°; Me, 4-CF₃, H, 154-6°; H, 4-OMe, H, 228-30°; H, OMe, Et, 104°; Me, 4-OMe, H, 164-6°; H, 5-Cl, Me, 157-8°; H, 5-Cl, Et, 127-8°; Me, 5-Cl, H, 160°; Me, 5-Cl, Me, 92-3°; H, 5-OMe, Me, 149°; H, 5-SMe, Et, 187-8°; Me, 5-SMe, Me, 102-3°; H, 6-Cl, Me, 119-20°; H, 5′-Cl, Et, 106-7°; H, 5′-OMe, H, 235-7°; H, 4′-Cl, H, 232-5°; H, 4′-Cl, Me, 138°; H, 4′-OMe, H, 240°; Me, 4′-OMe, H, 168-72°. To a cooled solution of 5.9 g. K in 110 ml. tert-BuOH was added under stirring 12 g. MeSH. At 20°, a solution of 40.3 g. I (R¹ = R³ = Me, R² = 5-Cl) in 300 ml. HCONMe₂ was added. After 2 hrs. stirring at 80°, evaporation to dryness in vacuo, distribution between benzene and NaHCO₃ solution, evaporation of the benzene, and crystallization from Et₂O/petr. ether gave 40 g. I (R¹ = R³ = Me, R² = 5-SMe), m. 102-3°. To 135.6 g. I (R¹ = R³ = H, R² = 5-Cl) 10.3, suspended in 1.8 l. 2N aqueous NH₃ was added within 3 hrs. 266 g. Na₂S₂O₄. The mixture was heated to 80° till solution was complete. Charcoal treatment, acidification to pH 4.5 with AcOH, addition of NaCl, and work-up gave 121.3 g. II (R¹ = R³ = H, R² = 5-Cl), m. 208-5° (decomposition) (MeOH-H₂O). Similarly prepared were the II derivatives (R¹, R², R³, m.p. given): H, 4-Me, H, 213-15°; Me, 4-Me, H, 144-6°; H, 4-Cl, H, 200-5°; Me, 4-Cl, H, 155°; H, 4-CF₃, H, 214-15°; Me, 4-CF₃, H, 160°; H, 4-OMe, H, 200°; Me, 4-OMe, H, 132-4°; H, 5-Cl, Me, 117-18°; Me, 5-Cl, H, 155°; H, 5-OMe, H, 178-9°; H, 5-SMe, H, 170-2°; H, 6-Cl, Me, 135-9°; H, 5′-Cl, H, 175-7°; H, 5′-OMe, H, 182-4°; H, 4′-Cl, H, 197-8°. II (R¹ = R³ = H, R² = 5-Cl) (121.3 g.) was refluxed in 3 l. xylene 40 hrs. under continuous removal of H₂O. After distillation of the solvent and vapor distillation for removal of impurities, the residue was made alkaline with dilute NH₃, filtered, treated with charcoal, and crystallized from Me₂CO-H₂O to give 71.3 g. III (R¹ = H, R² = 7-Cl), m. 253-4°. The same compound was also obtained by refluxing of 2.5 g. II (R¹ = H, R² = 5-Cl, R³ = Me) with 0.39 g. NaNH₂ in 20 ml. dioxane, dilution with H₂O, and filtration in 83% yield. Similarly prepared were the following III derivatives (R¹, R², m.p. given): H, 2-Cl, 259-60°; H, 2-OMe, 220-1°; Me, 2-OMe, 200-12°; H, 3-Cl, 271°; H, 3-OMe, 232-3°; H, 3-Me, 267-9°; H, 6-Cl, 244-6°; Me, 7-Cl, 226-7°; H, 7-OMe, 239-40°; H, 7-SMe, 211-12°; Me, 7-SMe, 225-6°; H, 8-Cl, 231-2°; Me, 8-Cl, 214-15°; H, 8-Me, 194-5°; Me, 8-Me, 228-9°; H, 8-CF₃, 176-7°; Me, 8-CF₃, 239-40°; H, 8-OMe, 174-6°; Me, 8-OMe, 221-3°. III (R¹ = H, R² = 7-Cl) (52.5 g.) was refluxed 1 hr. with 9.2 g. NaNH₂ in 350 ml. dioxane, then 29 g. ClCH₂CH₂NMe₂ in 50 ml. benzene was added and the mixture refluxed 16 hrs. Concentration in vacuo, distribution between benzene/H₂O, extraction of the benzene with diluted HCl, alkalinization of the extract with NH₃, extraction with CHCl₃, evaporation of the solvent, and crystallization from Me₂CO/Et₂O gave 50.8 g. IV (R¹ = H, R² = 7-Cl), m. 165-6°, _ε230 32,740 (EtOH); hydrochloride m. 225-33° (EtOH-Et₂O). The same compound was obtained by refluxing 11.4 g. II (R¹ = H, R² = 5-Cl, R³ = Me) 90 min. with 1.8 g. NaNH₂ in 90 ml. dioxane, then adding 6 g. ClCH₂CH₂NMe₂ in 20 ml. benzene, and refluxing 15 hrs. (and usual work-up) in 56% yield. Similarly prepared were the following IV derivatives (R¹ R², m.p. free base, m.p. hydrochloride, L.D.₅₉ mg./kg. mouse per os given): H, H, 112-14°, -, 705; Me, H, 116-17°, 234-40°, 215; H, 2-Cl, 172-3°, -, 175; Me, 2-OMe, -, 205-10°, 900; H, 3-Cl, 159-60°, -, 305; H, 3-OMe, 141-3°, -, 150; H, 6-Cl, 122-3°, -, 260; H, 7-Cl, 165-6°, 225-33°, 330; Me, 7-Cl, -, 247-53°, 500; H, 7-OMe, 152-3°, -, 220; H, 7-SMe, 126-9°, -, 345; Me, 7-SMe, -, 205-7°, 520; H, 8-Cl, 140-5°, -, -; Me, 8-Cl, -, 240-5°, 500; H, 8-OMe, 126-7°, -, 220; H, 8-CF₃, 115-18°, -, 150; Me, 8-CF₈, -, 222-6°, 240; H, 8-Me, 137-8°, -, 127; Me, 8-Me, -, 214-17°, 100. Also prepared were the V derivatives (X, m.p., D.L.₅₀ mg./kg. mouse per os given): 2-pyrrolidinoethyl, 159-60°, 700; 2-piperidinoethyl, 187-9°, 700; 2-morpholinoethyl, 220-2°, >2500; CH₂CHMeNMe₂, 197-9°, 320; (CH₂)₃NMe₂, 137-9°, 1000. Reduction of the corresponding oxo derivatives with LiAlH₄ in tetrahydrofuran gave the VI derivatives (R¹, R², m.p., L.D.₅₀ mg./kg. mouse per os given): H, H, (maleate m. 100°), 600; Me, H, – (maleate m. 149-51°), 760; H, Cl, 87-9°, 275. IV (R¹ = H, R² = 2-Cl) (20 g.) was refluxed 24 hrs. in 200 ml. 5N HCl. Concentration in vacuo, addition of NaOH, and isolation of the resulting base gave 14.8 g. VII, b_8.97 130-8°. Acetylation with Ac₂O in pyridine gave VIII, m. 109-11°. To prove the structure, VIII was also synthesized independently. Thus, IX was acetylated to give X, m. 89-90° (Et₂O-petr. ether). X (31 g.) was alkylated with 4 g. NaNH₂ and 9.5 g. ClCH₂CH₂NMe₂ in 150 ml. dioxane to give after usual work-up 31.5 g. VIII. To test the influence of the N bridge on the pharmacol. properties, XI was prepared by refluxing 11.7 g. phenanthridone with 2.95 g. NaNH₂ in 120 ml. dioxane for 2 hrs. Addition of 7 g. ClCH₂CH₂NMe₂ in 50 ml. dioxane during 4 hrs., refluxing for 10 hrs, and normal work-up gave XI; hydrochloride m. 268-70° (MeOH-Et₂O). The XII derivatives were also prepared (X, m.p., L.D.₅₀ mg./kg. mouse per os given): S, 268-71° (hydrochloride) 870; SO₂, 113-23°, 620; O, 230-3° (hydrochloride), 500. The influence of the chem. constitution on the pharmacological activity was studied. A heterocyclic bridge in position 5 is indispensable for activity; derivatives of benzanilide and phenanthridone having basic substituents are inactive. An unsubstituted NH-group in position 5 has a more favorable effect than the Me-substituted N and is superior in activity to other hetero-bridges such as SO₂, S, and O. Compounds with substituents in position 7 show greater activity than the unsubstituted compound A carbonyl group in position 11 is essential for activity, the corresponding VI derivatives, although closely related to known antihistamines of the benzylaniline group are practically inactive in vivo. In agreement with other classes of antihistamines, the (CH₂)₂NMe₂ and (CH₂)₃NMe₂ groups are the most effective basic substituents. IV (R¹ = H, R² = 7-Cl) and the corresponding 7-SMe derivative belong to the most potent antihistaminics of today.

Arzneimittel-Forschung published new progress about 60091-87-4. 60091-87-4 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Nitro Compound,Carboxylic acid,Amine,Benzene, name is 2-((4-Chloro-2-nitrophenyl)amino)benzoic acid, and the molecular formula is C13H9ClN2O4, Quality Control of 60091-87-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Coutrot, Philippe published the artcileSynthesis of diethyl 1,1-dichloroalkane- and 1-chloroalkanephosphonates, Computed Properties of 866-23-9, the publication is Synthesis (1977), 615-17, database is CAplus.

RCCl2P(O)(OEt)2 (I, R = Me, Et, Pr, Bu, CH2:CHCH2, MeCH:CHCH2, MeOCH2) and RR1CClP(O)(OEt)2 (II, R = Me, Et, Pr, Bu; R1 = H, Me, Et, Bu, CH2:CHCH2, Cl(CH2)3) (11 compounds) were prepared in 42-81 and 66-89% yields resp. Thus, alkylation of (EtO)2P(O)CCl2Li with RBr in presence of PO(NMe2)3 at -80° gave I. Lithiation of I followed by alkylation with R1X (X = Br, iodo) gave II.

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Computed Properties of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Bel’skii, V. E. published the artcileStructure and chemical shifts in phosphorus-31 NMR of phosphonic acid esters, Safety of Diethyltrichloromethylphosphonate, the publication is Zhurnal Obshchei Khimii (1972), 42(11), 2427-31, database is CAplus.

The induction constants σ* of R groups correlated linearly with the chem. shift of 31P in 37 RP(O)(OEt)2 (R = alkyl or substituted alkyl groups), provided that hyperconjugation effects were taken into account. The presence of unshared electron pairs in R at the C atom adjacent to the P destroyed the linear relationship; the same was true of R groups containing multiple bonds.

Zhurnal Obshchei Khimii published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Safety of Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abdeen, Sanofar published the artcileSulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA), Recommanded Product: 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, the publication is Journal of Medicinal Chemistry (2018), 61(16), 7345-7357, database is CAplus and MEDLINE.

Extending from a study we recently published examining the anti-trypanosomal effects of a series of GroEL/ES inhibitors based on a pseudo-sym. bis-sulfonamido-2-phenylbenzoxazole scaffold, here, we report the antibiotic effects of asym. analogs of this scaffold against a panel of bacteria known as the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species). While GroEL/ES inhibitors were largely ineffective against K. pneumoniae, A. baumannii, P. aeruginosa, and E. cloacae (Gram-neg. bacteria), many analogs were potent inhibitors of E. faecium and S. aureus proliferation (Gram-pos. bacteria – EC₅₀ values of the most potent analogs were in the 1-2 μM range). Furthermore, even though some compounds inhibit human HSP60/10 biochem. functions in vitro (IC₅₀ values in the 1-10 μM range), many of these exhibited moderate to low cytotoxicity to human liver and kidney cells (CC₅₀ values >20 μM).

Journal of Medicinal Chemistry published new progress about 32333-53-2. 32333-53-2 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Sulfonyl chlorides,Benzene, name is 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, and the molecular formula is C7H3Cl2F3O2S, Recommanded Product: 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Lipatova, I. P. published the artcileElectron-donor capability of the phosphoryl group of some trichloromethyl derivatives of phosphorus(V) studied by an ir spectroscopic method, Name: Diethyltrichloromethylphosphonate, the publication is Zhurnal Obshchei Khimii (1975), 45(2), 287-9, database is CAplus.

Heats of the H bonding of 16 title compounds, e.g., EtPhP(O)CCl3, p-MeC6H4P(CCl3)(O)OPr, and CCl3P(O)(OBu)2, with PhOH were determined via ir and correlated with resonance and inductive effects of the substituents.

Zhurnal Obshchei Khimii published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Name: Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Silina, E. B. published the artcileα-Bromoalkyl isocyanates and their phosphorylated derivatives, Computed Properties of 18791-02-1, the publication is Zhurnal Obshchei Khimii (1989), 59(3), 571-86, database is CAplus.

Reaction of Br₃CNCO with ROPX₂ (R = Me, Et, X = Cl; R = Bu, X = F) in the presence of FeCl₃ gave 27-58% X₂P(O)CBr₂NCO. Arbuzov reaction of BrCH₂CHBrNCO with (R¹O)₃P (R¹ = Et, Me) or with halophosphites (EtO)₂PX (X = Cl, F) or EtOPX₂ (X = Cl, F) gave (R¹O)₂P(O)CH(CH₂Br)NCO (I; same R¹), 40-60% EtOPX(O)CH(CH₂Br)NCO (II; same X), or 54-72% X₂P(O)CH(CH₂Br)NCO (III; same X), resp. Treating I (R¹ = Et) and II–III with Et₃N gave 48-75% ethylene isocyanates (EtO)_n(X)_2-nP(O)C(:CH₂)NCO (IV; n = 0-2; X = Cl, F), which when treated with Br₂ gave 33-68% (EtO)_n(X)_2-nP(O)CBr(CH₂Br)NCO (V). Reaction of III (X = Cl) or IV (n = 0; X = Cl) with R²OH (R² = Me, Et) and Et₃N gave 73-87% carbamates (R²O)₂P(O)C(:CH₂) NHCO₂R. III (X = F) and IV (n = 0, X = F) reacted with PhNH₂ to give 65-81% anilides F₂P(O)CH(CH₂Br)NHCONHPh and F₂P(O)C(:CH₂)NHCONHPh, resp. ¹H, ¹⁹F, and ³¹P NMR spectra of III–V are discussed.

Zhurnal Obshchei Khimii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C10H9N3O, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics