Tag: M.W=250-300

Swain, Asim Kumar published the artcilePyrene-Fused [7]Helicenes Connected Via Hexagonal and Heptagonal Rings: Stereospecific Synthesis and Chiroptical Properties, Product Details of C10H15ClO3S, the publication is Journal of Organic Chemistry (2022), 87(2), 993-1000, database is CAplus and MEDLINE.

In this manuscript, stereospecific synthesis of C2- and C1-sym. pyrene fused [7]helicene compounds I and II, resp. was portrayed. Compounds I and II were synthesized via one-pot Suzuki coupling-C-H activation and two-step Suzuki coupling-Scholl reaction, resp., with complete retention of configuration. The synthesized mols. differ in the fusing mode of [7]helicene units with pyrene via six- and seven-membered rings for compounds I and II, resp. There was a significant difference in the functional properties and enantiomerization barrier of both compounds because of their distinct mol. symmetry as well as fusing mode to pyrene moiety. The heptagon containing mol. II showed remarkable photophys. and chiroptical properties with commendable configurational stability compared to compound I and pristine [7]helicene as well as its [5]helicene congener.

Journal of Organic Chemistry published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C8H8O2, Product Details of C10H15ClO3S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Padmavathi, V. published the artcileSynthesis of novel bis heterocycles: bis pyrroles, pyrrolyl pyrazolines and pyrrolyl isoxazolines, Product Details of C7H13ClNNaO5S, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2008), 47B(11), 1707-1712, database is CAplus.

The Michael acceptors, 1-arylsulfonyl-2-styrylsulfonylethenes were used as synthons to develop bis pyrroles, pyrrolyl pyrazolines and pyrrolyl isoxazolines by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, nitrile imines and nitrile oxides.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chandra published the artcile3-(4-Methoxyphenyl)-5-methylisoxazole-4-carboxylic acid, Recommanded Product: Sodium chloro(tosyl)amide trihydrate, the publication is Acta Crystallographica, Section E: Structure Reports Online (2013), 69(3), o388, database is CAplus and MEDLINE.

In the title compound, C₁₂H₁₁NO₄, the dihedral angle between the benzene and isoxazole rings is 42.52(8)°. The carboxylic acid group is close to being coplanar with the isoxazole ring [dihedral angle = 5.3(2)°]. In the crystal, inversion dimers linked by pairs of O-H···O hydrogen bonds generate R₂²(8) loops.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Recommanded Product: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Padmaja, A. published the artcileSynthesis and antioxidant activity of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles, Product Details of C7H13ClNNaO5S, the publication is European Journal of Medicinal Chemistry (2011), 46(10), 5034-5038, database is CAplus and MEDLINE.

A new class of oxazolyl/thiazolylsulfonylmethyl pyrazoles I(X= O, S, R = H, Me, Cl) and II(X= O, S, R¹ = R² = H, cl; X= O, S, R¹ = Me, R² = MeO) and isoxazoles III(X= O, S, R¹ = R² = H, cl; X= O, S, R¹ = Me, R² = MeO) were prepared from the synthetically vulnerable intermediate E-styrylsulfonylacetic acid Me ester and studied their antioxidant activity.

European Journal of Medicinal Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Comstock, Lindsay R. published the artcileExpeditious synthesis of aziridine-based cofactor mimics, Name: 2,3-Dibromopropionylchloride, the publication is Tetrahedron (2002), 58(30), 6019-6026, database is CAplus.

S-Adenosyl-L-methionine mimics were synthesized in a linear fashion highlighting methodol. that bypasses the need for adenine base protection. These aziridine-based cofactor mimics are envisioned as useful biochem. tools and potential therapeutic agents whose mechanism of action hinges upon aberrant methyltransferase enzymes. Aziridination of the 5′ position of adenosine was effected by convergence of suitably protected 5′-aminoadenosine with various dibromopropionates. The economy and high yields for this route to said aziridine-based cofactors is highly amenable to large-scale chem. which no doubt will be vital to their development as therapeutics and biochem. tools.

Tetrahedron published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Name: 2,3-Dibromopropionylchloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mal, Sanjib published the artcileFacile one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazines via oxidative cyclisation using chloramine T, Category: chlorides-buliding-blocks, the publication is Tetrahedron Letters (2015), 56(22), 2896-2901, database is CAplus.

A facile and expedient one pot synthesis of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives I [R¹ = H, Cl; R = Ph, 3-MeO-C₆H₄, 4-Br-C₆H₄, etc.] from 2-chloro-3-hydrazinylpyrazine and aldehydes is described using chloramine T trihydrate as a safe and convenient electrocyclisation (oxidising) agent. The presence of the chloro group on pyrazine enabled us to access versatile new synthetic scaffolds II [R¹ = Ph, 2-thiophenyl, 2,4-diCl-C₆H₃] by easy diversification using palladium catalyzed Suzuki-Miyaura and Sonogashira cross coupling reactions. The products are obtained in high yields in short reaction time under mild conditions without the need for chromatog. purification

Tetrahedron Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Yakubenko, Artyom A. published the artcileSelf-association of diphenylpnictoginic acids in solution and solid state: covalent vs. hydrogen bonding, Quality Control of 7080-50-4, the publication is Physical Chemistry Chemical Physics (2022), 24(13), 7882-7892, database is CAplus and MEDLINE.

Triphenylpnictogens were oxidized to access diphenylpnictioginic acids Ph₂XOOH (X = P, As, Sb, Bi). Oxidation with chloramine-T does not lead to the cleavage of a C-pnictogen bond. The preliminary reductive cleavage with sodium in liquid ammonia followed by the oxidation with hydrogen peroxide was successfully used for the synthesis of diphenylphosphinic and diphenylarsinic acids. In solid state (by XRD), all diphenylpnictoginic acids form polymeric chains. Diphenylbismuthinic and diphenylantimonic acids form polymeric covalent adducts, while diphenylphosphinic and diphenylarsinic chains are associated through hydrogen bonding. Unlike diphenylphosphinic acid, diphenilarsinic acid forms two polymorphs of hydrogen-bonded infinite chains. In solution in a polar aprotic solvent diphenylarsinic acid, similarly to dimethylarsinic, forms hydrogen-bonded cyclic dimers together with a small amount of cyclic trimers.

Physical Chemistry Chemical Physics published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C9H20Cl2Si, Quality Control of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zamani, Farzad published the artcileOxazolidinones and 2,5-Dihydrofurans via Zinc-Catalyzed Regioselective Allenylation Reactions of L-α-Amino Aldehydes, Computed Properties of 21286-54-4, the publication is Journal of Organic Chemistry (2017), 82(13), 6819-6830, database is CAplus and MEDLINE.

The simultaneous control of diastereoselectivity and regioselectivity in Zn-catalyzed allenylation reactions of N-protected L-α-amino aldehydes is reported. A reversal in diastereoselectivity could be realized by variation of the α-amino aldehyde protecting groups. A range of 1-allenyl-2-amino alcs. were obtained with excellent regioselectivity and converted to oxazolidinones and dihydrofurans. Many oxazolidinones and dihydrofuran could be isolated as single diastereoisomers and without significant erosion of ee, making this a practical catalytic synthesis of highly functionalized heterocycles.

Journal of Organic Chemistry published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C4H7BrO2, Computed Properties of 21286-54-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Eremeev, A. V. published the artcileAsymmetric unbridged nitrogen. 37. Absolute configuration of diastereomeric derivatives of N-substituted aziridine-2-carboxylic acids, Computed Properties of 18791-02-1, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1984), 1343-8, database is CAplus.

Both (R,S)- and (S,S)-aziridinecarboxanilides (I; R, R¹ = Me, H; Me, Br; CHMe₂, Br) were prepared and the diastereoisomers distinguished by their ¹H and ¹⁵N NMR and CD spectra.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Olmstead, Marilyn M. published the artcileCrystal and molecular structure of chloramine-T trihydrate. Absence of a sodium-nitrogen interaction in the oxidant. N-chloro-N-sodiotoluene-p-sulfonamide, Product Details of C7H13ClNNaO5S, the publication is Inorganic Chemistry (1986), 25(22), 4057-8, database is CAplus.

The title compound is triclinic, space group PT, with a 6.393(1), b 7.510(1)8 c 13.767(2) Å, α 85.33(1), β 83.92(1), and γ 74.11(1)°; Z = 2. Final R = 0.039 for 2366 data. At. coordinates are given. The main feature of the structure involves the lack of the commonly represented interaction between Na and N. Instead, the Na ion is coordinated to one of the sulfonamide oxygens. The rest of the Na coordination sphere involves oxygens (from water of crystallization) and a Cl from a neighboring mol. The structure is the first for an [RSO₂NCl]^– moiety.

Inorganic Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics