Tag: M.W=250-300

Chen, Shuqing published the artcileRedox-neutral ortho-C-H amination of pinacol arylborates via palladium(II)/norbornene catalysis for aniline synthesis, Recommanded Product: 2-(4-Chloro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, the publication is Chemical Science (2019), 10(36), 8384-8389, database is CAplus and MEDLINE.

A palladium(II)/norbornene cooperative catalysis enabled redox-neutral ortho-C-H amination of pinacol aryl- or heteroarylborates for the synthesis of structurally diverse anilines was reported. The method was scalable, robust (tolerance of air and moisture), phosphine ligand-free and compatible with a wide range of functionalities. These practical features made this reaction amenable for industry. A plethora of synthetically very useful halogenated anilines which often cannot be prepared via other transition-metal-catalyzed aminations were readily produced using this method. Particularly, the orthogonal reactivity between pinacol arylborates and aryl iodides was demonstrated. Preliminary deuterium-labeling studies revealed a redox-neutral ipso-protonation mechanism of this process, which will surely inspire the future development of this field. Overall, the exceptionally broad scope (47 examples) and reliability of this procedure, together with the wide availability of pinacol arylborates made this chem. a valuable addition to the existing methods for aniline synthesis.

Chemical Science published new progress about 1030832-75-7. 1030832-75-7 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Boronic acid and ester,Benzene,Boronate Esters,Boronic acid and ester, name is 2-(4-Chloro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C13H18BClO2, Recommanded Product: 2-(4-Chloro-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Chen, Pengquan published the artcileAsymmetric Total Synthesis of Dankasterones A and B and Periconiastone A Through Radical Cyclization, Quality Control of 21286-54-4, the publication is Angewandte Chemie, International Edition (2021), 60(10), 5512-5518, database is CAplus and MEDLINE.

We describe herein the assembly of the cis-decalin framework through radical cyclization initiated by metal-catalyzed hydrogen atom transfer (MHAT), further applied it in the asym. synthesis of dankasterones A and B and periconiastone A. Position-selective C-H oxygenation allowed for installation of the necessary functionality. A radical rearrangement was adopted to create 13(14�)abeo-8-ergostane skeleton. Interconversion of dankasterone B and periconiastone A was realized through biomimetic intramol. aldol and retro-aldol reactions. The MHAT-based approach, serves as a new dissection means, is complementary to the conventional ways to establish cis-decalin framework.

Angewandte Chemie, International Edition published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C10H15ClO3S, Quality Control of 21286-54-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Jiawei published the artcileZinc-Catalyzed Hydroxyl-Directed Regioselective Ring Opening of Aziridines in S_N2 Reaction Pathway, Product Details of C7H13ClNNaO5S, the publication is ACS Catalysis (2020), 10(1), 556-561, database is CAplus.

In this protocol, a zinc-catalyzed catalytic regioselective ring opening of electronically and sterically unbiased 2,3-aziridinyl alcs. has been accomplished. The directing effect of the hydroxyl moiety enables the selective nucleophilic attack to the C-3 position of 2,3-aziridinyl alcs. with various aromatic amines and thiophenols as nucleophiles. This operationally simple reaction provides convenient access to a variety of amino alcs. and hydroxyl sulfides in excellent regiocontrol. Moreover, simple derivatization of the ring opening product establishes a general strategy to approach internal vicinal diamines in regioselective and diastereomerically pure form.

ACS Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wu, Xue-Liang published the artcileAminochlorination in Water: First Bronsted Acid-Promoted Synthesis of Vicinal Chloramines, HPLC of Formula: 7080-50-4, the publication is Journal of Organic Chemistry (2007), 72(24), 9398-9401, database is CAplus and MEDLINE.

A practical and scalable route for the regioselective and diastereoselective synthesis of vicinal chloro amines from electron-deficient olefins and Chloramine-T promoted by Bronsted acids in water has been realized for the first time. This novel protocol is efficient, mild, ecofriendly, and broadly applicable for the aminochlorination of various electron-deficient olefins including α,β-unsaturated ketones, cinnamate and cinnamamide. Water represents as a privileged solvent for the aminochlorination reaction in the authors’ reaction system.

Journal of Organic Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C3H5BN2O2, HPLC of Formula: 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Huang, Benhua published the artcileSynthesis of mesoporous zirconium-containing silicates and their application for catalytic asymmetric addition of diethylzinc to aldehydes, Product Details of C10H15ClO3S, the publication is Journal of Porous Materials (2017), 24(4), 867-879, database is CAplus.

A series of mesoporous zirconium-containing silicates were prepared in sol-gel, which were further functionalized by chiral sulfonyl chloride and proline for catalytic asym. addition of diethylzinc to aldehydes. These materials had good porosities, hexagonal symmetries and internal chiralities. Moreover, significant morphol. variations were observed when preparative conditions were changed. These materials also showed good to excellent enantioselectivities in catalysis, and there was chiral induction synergy between silicate matrix and attached ligand. Recycling of catalyst was tested, and promising results were obtained. This study would contribute to the design of mesoporous chiral catalysts.

Journal of Porous Materials published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C10H15ClO3S, Product Details of C10H15ClO3S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Okawara, Tadashi published the artcileSynthesis of new uracils having N-amino-β-, -γ-, and -δ-lactams, COA of Formula: C3H3Br2ClO, the publication is Heterocycles (1988), 27(8), 1881-5, database is CAplus.

The reaction of 1,3-dimethyl-6-methylhydrazinouracil with R(CH₂)_nCR¹R²COCl (R = Br, Cl; R¹,R² = H, Me, Br; n = 1-5) afforded N-haloacylhydrazinouracils I, which were converted into the lactams II by treatment with KOH in the presence of TEBAC.

Heterocycles published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, COA of Formula: C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Myannik, A. O. published the artcileSynthesis and properties of some esters of phosphoric, thiophosphoric, and phosphonic acids, Application In Synthesis of 866-23-9, the publication is Neftekhimiya (1964), 4(6), 899-905, database is CAplus.

The influence of the trichloromethyl group in different esters of phosphoric, thiophosphoric, and alkylphosphorous esters on their antiabrasive properties were studied. The following compounds prepared by known methods [b.p. (mm.), d₂₀, n²⁰_D), and MR_D given]: iso-AmOP(O)(OEt)₂, 85-8°(3), 1.0164, 1.4150, 55.21; CCl₃CH₂OP(O)(OEt)₂, 119-20°(4), 1.3473, 1.4490, 56.85; CCl₃CH₂OP(O)(OBu)₂, 126-7°(2), 1.2097, 1.4480, 75.48; CCl₃(CH₂)₄OP(O)(OEt)₂, 155-6°(2), 1.2685, 1.4850, 70.48; CCl₃(CH₂)₄OP(O)(OBu)₂, 196-7°(2), 1.1637, 1.4550, 89.39; AmSP(O)(OEt)₂, 145-6°(6), 1.0434, 1.4575, 62.73; Me(CH₂)₈SP(O)(OEt)₂, 177-8°(2), 0.9985, 1.4600, 81.19; CCl₃(CH₂)₄SP(O)(OEt)₂, 165-7°(2), 1.2892, 1.4940, 77.40; CCl₃(CH₂)₄SP(O)(OPr)₂, 186-7°(2), 1.2226, 1.4890, 87.45; CCl₃(CH₂)₄SP(O)(OBu-iso)₂, 183-4°(2), 1.1875, 1.4850, 96.42; CCl₃(CH₂)₈SP(O)(OEt)₂, 217- 18°(2), 1.1900, 1.4885, 96.80; EtOP(S)(OEt)₂, 88-9°(8), 1.0746, 1.4480, 49.33; BuOP(S)(OEt)₂, 120-1°(5), 1.0412, 1.4505, 58.40; CCl₃CH₂OP(S)(OEt)₂, 130-1°(3), 1.3414, 1.4840, 64.32; CCl₃(CH₂)₄OP(S)(OEt)₂, 153-4°(4), 1.2647, 1.4873, 78.14; MeP(O)(OEt)₂, 74-5°(10), 1.0685, 1.4140, 35.53; MeP(O)(OAm)₂, 98-9°(2), 0.9618, 1.4307, 63.33; CCl₃P(O)(OEt)₂, 88-9°(2), 1.3738, 1.4645, 51.30; CCl₃P(O)(OAm)₂, 123-4°(1), 1.1745, 1.4601, 79.01; MeP(O)OCH₂CCl₃)₂, –(m. 63-3.5°), –, –, –; MeP(O)[O(CH₂)₄CCl₃₂, 177-8°(1), 1.3838, 1.4941, 92.91; CCl₃P(O)(OCH₂CCl₃)₂ –(m. 94-94.5°),–, –, –.

Neftekhimiya published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Application In Synthesis of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Myannik, A. O. published the artcileThe effect of composition of some esters of phosphoric and phosphonic acids on their activity as mixtures, in decreasing friction wear, SDS of cas: 866-23-9, the publication is Teoriya Smazochnogo Deistviya i Novye Materialy (1965), 63-7, database is CAplus.

H₃PO₄ esters were synthesized from dialkylphosphoric acid chlorides and of alcs. Almost all the esters are liquids soluble in hydrocarbons and lubricating oils. The experiment was carried by adding 6 millimoles of ester to 100 g. oil (1.4-2.2%). Wear-load curves were constructed. H₃PO₄ esters considerably increase the critical load (80 kg.) for pure lubricating oil to 150 kg., after addition of diethyl isoamyl phosphate, and to 227 kg. after addition of diethyl trichloropentyl phosphate. Increasing wear resistance is seen after addition of compounds containing (RO₂)P(:S) S < (RO)₂P(:S)O < (RO)₂P(:O)S < (RO)₂P(:O)O groups. The addition of methyl- and trichloromethyl phosphonic acids increases the load to 300 kg.

Teoriya Smazochnogo Deistviya i Novye Materialy published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, SDS of cas: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanin, P. I. published the artcileEffect of lubricating oil additives on wear under friction, Related Products of chlorides-buliding-blocks, the publication is Wear (1960), 200-18, database is CAplus.

Additives in an oil with a viscosity of 20.8 centistokes at 50° were tested in a modified 4-ball machine for reduction of wear and load-carrying capacity. Chlorinated compounds, such as methyl dichlorostearate, tetrachloronaphthalene, and chlorinated wax fractions increase the critical load and lower frictional wear by chem. reaction at high temperature Optimum results were obtained with >7% of chlorinated fractions containing >40% Cl. Tests on organic S-P compounds indicated that the activity of organic phosphites depends on the structure of the hydrocarbon radical; e.g., the critical load for an oil containing tripropyl trithiophosphite is 110 kg., almost twice that of the base oil or of the oil containing tri-noctadecyl trithiophosphite. Only lower trialkyl trithiophosphites with C₃-C₅ alkyls, are potential additives for increasing the lubricating properties of oils; trialkylthiophosphates are less active. Butyl esters of phosphorous, phosphoric, thiophosphorous, and thiophosphoric acids are active additives. Increasing the S content of phosphites, and particularly of phosphates, resulted in a reduction of the critical load but reduced wear above the critical load by formation of a sulfide film on the frictional surfaces under heavy load and at high temperature P in the mol. increased the critical load and S improved frictional behavior. Cl reduced wear even more than S. Phosphonic compounds were more active than compounds containing alkoxy groups, e.g., trichloromethyl phosphonates (I) and dichloroethyl chloroethylphosphonate increased the critical load from 68 to 140-50 kg. and reduced wear at loads higher than the critical load. Tetrachloroalkanes increased the critical load and reduced wear above the critical load but compounds containing the CCl₃ group and P, such as I, are markedly more active owing to action of the trichloromethyl group and of P from additive decomposition Increasing the number of CCl₃ groups in the mol. of organic P compounds enabled an oil containing such an additive to carry enormous loads without seizure, e.g., tri(trichloroethyl)phosphite and tri(trichloro-tert-butyl)phosphite reduced wear to lower than 0.8 mm. at 300 kg. loads. 21 references.

Wear published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fu, Ying published the artcileA visible-light photoinduced charge-transfer complex promoted the ring opening of N-alkyl-4-piperidinols, Safety of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, the publication is Green Chemistry (2020), 22(7), 2264-2269, database is CAplus.

A visible-light photoinduced ring opening of N-alkyl-4-piperidinols under mild conditions was achieved. The reaction sequence involved a visible-light-induced charge-transfer complex, which promoted the S-Cl bond cleavage of sulfonyl chlorides. The generated sulfonyl radical further reacts with N-alkyl-4-piperidinol cation radicals to achieve C-N and C-C bond cleavages to yield homoallylamine products.

Green Chemistry published new progress about 32333-53-2. 32333-53-2 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Sulfonyl chlorides,Benzene, name is 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride, and the molecular formula is C7H3Cl2F3O2S, Safety of 4-Chloro-3-(trifluoromethyl)benzenesulfonyl Chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics