Tag: M.W=150-200

An article Nine Supramolecular Adducts of 4-dimethylaminopyridine and Carboxylic acids Assembled by Classical Hydrogen Bonds and Other Noncovalent Intermolecular Interactions WOS:000663587500014 published article about PROTON-TRANSFER COMPOUNDS; SOLID-STATE LANDSCAPE; CRYSTAL-STRUCTURE; STRUCTURAL-CHARACTERIZATION; PHARMACEUTICAL COCRYSTALS; MOLECULAR-STRUCTURE; ORGANIC SALTS; SOLUBILITY; SYNTHON; ARCHITECTURES in [Chen, Bin; Wu, Ronghui; Jin, Shouwen; Bai, Liqun] Zhejiang A&F Univ, Linan 311300, Peoples R China; [Chen, Bin; Lin, Zhihao; Jin, Shouwen; Dong, Lingfeng; Xu, Weiqiang] Zhejiang A&F Univ, Jiyang Coll, Zhuji 311800, Zhejiang, Peoples R China; [Wang, Daqi] Liaocheng Univ, Dept Chem Engn, Liaocheng 252059, Shandong, Peoples R China in 2021, Cited 86. COA of Formula: C7H4Cl2O2. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0

Cocrystallization of the widely available 4-dimethylaminopyridine, with a series of carboxylic acids gave nine molecular adducts 4-dimethylaminopyridinium trifluoroacetate (1) , 4-dimethylaminopyridinium glycolate glycolic acid (2) , 4-dimethylaminopyridinium 2-furoate dihydrate (3) , tri(4-dimethylaminopyridinium) tri(o-chlorobenzoate) tetrahydrate (4) , 4-dimethylaminopyridinium 4-bromobenzoate 4-bromobenzoic acid (5) , 4-dimethylaminopyridinium 4-formylbenzoate 4-formylbenzoic acid (6) , 4-dimethylaminopyridinium 2,4-dichlorobenzoate (7) , 4-dimethylaminopyridinium 2-aminobenzoate 2-aminobenzoic acid (8) and bis(4-dimethylaminopyridinium) 5-nitroisophthalate 5-nitroisophthalic acid methanol solvate (9) . The nine adducts have been characterised by X-ray diffraction, IR and elemental analysis, the melting points were also reported. Their structural and supramolecular aspects are fully analyzed. The result reveals that among the nine investigated crystals only the ring Ns in the 4-dimethylaminopyridine moieties are protonated when the carboxylic acids are deprotonated. The crystal packing is interpreted by the strong charge-assisted N-H center dot center dot center dot O hydrogen bond between the NH+ and the deprotonated acidic groups. Except the N-H center dot center dot center dot O hydrogen bonds, the charge assisted or neutral O-H center dot center dot center dot O hydrogen bonds were also found at 2-6, 8 and 9 . The COOH center dot center dot center dot COO- synthon has been at 2, 5-6 and 8-9. Further analysis of the crystal packing indicated that a different family of additional CH-O/CH2-O/CH3-O, F-F, Br-Br, CH-Cl, CH3-Cl, CH-pi/CH3-pi, C-H center dot center dot center dot C-pi, C-pi, Cl-O, O-C, O-pi and pi-pi contacts contribute to the stabilization and expansion of the total high-dimensional (2D-3D) framework structures. For the synergism of the various nonbonding contacts there created homo/hetero supramolecular synthons or both. (C) 2021 Elsevier B.V. All rights reserved.

COA of Formula: C7H4Cl2O2. About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Chen, B; Lin, ZH; Wu, RH; Jin, SW; Dong, LF; Bai, LQ; Xu, WQ; Wang, DQ or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about PROTON-TRANSFER COMPOUNDS; SOLID-STATE LANDSCAPE; CRYSTAL-STRUCTURE; STRUCTURAL-CHARACTERIZATION; PHARMACEUTICAL COCRYSTALS; MOLECULAR-STRUCTURE; ORGANIC SALTS; SOLUBILITY; SYNTHON; ARCHITECTURES, Saw an article supported by the Zhejiang Provincial Natural Science Foundation of ChinaNatural Science Foundation of Zhejiang Province [LY14B010006]; Open Foundation of Key Laboratory of Chemical Utilization of Forestry Biomass of Zhejiang Province, Zhejiang A F University [2015CUFB02]; Jiyang 533 project. Recommanded Product: 50-84-0. Published in ELSEVIER in AMSTERDAM ,Authors: Chen, B; Lin, ZH; Wu, RH; Jin, SW; Dong, LF; Bai, LQ; Xu, WQ; Wang, DQ. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid

Cocrystallization of the widely available 4-dimethylaminopyridine, with a series of carboxylic acids gave nine molecular adducts 4-dimethylaminopyridinium trifluoroacetate (1) , 4-dimethylaminopyridinium glycolate glycolic acid (2) , 4-dimethylaminopyridinium 2-furoate dihydrate (3) , tri(4-dimethylaminopyridinium) tri(o-chlorobenzoate) tetrahydrate (4) , 4-dimethylaminopyridinium 4-bromobenzoate 4-bromobenzoic acid (5) , 4-dimethylaminopyridinium 4-formylbenzoate 4-formylbenzoic acid (6) , 4-dimethylaminopyridinium 2,4-dichlorobenzoate (7) , 4-dimethylaminopyridinium 2-aminobenzoate 2-aminobenzoic acid (8) and bis(4-dimethylaminopyridinium) 5-nitroisophthalate 5-nitroisophthalic acid methanol solvate (9) . The nine adducts have been characterised by X-ray diffraction, IR and elemental analysis, the melting points were also reported. Their structural and supramolecular aspects are fully analyzed. The result reveals that among the nine investigated crystals only the ring Ns in the 4-dimethylaminopyridine moieties are protonated when the carboxylic acids are deprotonated. The crystal packing is interpreted by the strong charge-assisted N-H center dot center dot center dot O hydrogen bond between the NH+ and the deprotonated acidic groups. Except the N-H center dot center dot center dot O hydrogen bonds, the charge assisted or neutral O-H center dot center dot center dot O hydrogen bonds were also found at 2-6, 8 and 9 . The COOH center dot center dot center dot COO- synthon has been at 2, 5-6 and 8-9. Further analysis of the crystal packing indicated that a different family of additional CH-O/CH2-O/CH3-O, F-F, Br-Br, CH-Cl, CH3-Cl, CH-pi/CH3-pi, C-H center dot center dot center dot C-pi, C-pi, Cl-O, O-C, O-pi and pi-pi contacts contribute to the stabilization and expansion of the total high-dimensional (2D-3D) framework structures. For the synergism of the various nonbonding contacts there created homo/hetero supramolecular synthons or both. (C) 2021 Elsevier B.V. All rights reserved.

About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Chen, B; Lin, ZH; Wu, RH; Jin, SW; Dong, LF; Bai, LQ; Xu, WQ; Wang, DQ or concate me.. Quality Control of 2,4-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about EFFICIENT HETEROGENEOUS CATALYST; SCHIFF-BASE COMPLEX; SELECTIVE OXIDATION; AEROBIC OXIDATION; CARBOXYLIC-ACID; PYRIDINIUM CHLOROCHROMATE; RECYCLABLE CATALYST; SECONDARY ALCOHOLS; DIMETHYL-SULFOXIDE; MANGANESE-DIOXIDE, Saw an article supported by the Tarbiat Modares University. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Nejad, MJ; Salamatmanesh, A; Heydari, A. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid. Category: chlorides-buliding-blocks

Copper (II) immobilized on L-arginine-beta-cyclodextrin-functionalized magnetite nanoparticles (nano-Fe3O4@L-arginine-CD-Cu(II)) were successfully synthesized and fully characterized using FT-IR, XRD, SEM, EDX, ICP, TGA and VSM techniques. The catalytic activity of these magnetically retrievable nanoparticles was evaluated in the direct oxidation of primary alcohols and benzyl halides to acids in neat conditions that was observed to proceed well and products were obtained in good yields. In addition to showing good catalytic activity, the magnetic catalyst is easy to synthesize and can be recycled at least five times with little loss in activity. (C) 2020 Elsevier B.V. All rights reserved.

About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Nejad, MJ; Salamatmanesh, A; Heydari, A or concate me.. Computed Properties of C7H4Cl2O2

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Authors Wang, ZX; Wu, XF; Li, ZN; Huang, ZD; Chen, F in ROYAL SOC CHEMISTRY published article about ASYMMETRIC REDUCTION; CARBONYL REDUCTASE; DERIVATIVES; CONVERSION; ALCOHOLS in [Wang, Zexu; Li, Zhining; Huang, Zedu; Chen, Fener] Fudan Univ, Dept Chem, Engn Ctr Catalysis & Synth Chiral Mol, 220 Handan Rd, Shanghai 200433, Peoples R China; [Wang, Zexu; Li, Zhining; Huang, Zedu; Chen, Fener] Shanghai Engn Res Ctr Ind Asymmetr Catalysis Chir, 220 Handan Rd, Shanghai 200433, Peoples R China; [Wu, Xiaofan] Fuzhou Univ, Coll Chem Engn, 2 Xueyuan Rd, Fuzhou 350100, Fujian, Peoples R China in 2019, Cited 29. Quality Control of 2,4-Dichlorobenzoic acid. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0

We report here the stereoselective bioreduction of -nitro ketones catalyzed by ketoreductases (KREDs) with publicly known sequences. YGL039w and RasADH/SyADH were able to reduce 23 class I substrates (1-aryl-2-nitro-1-ethanone (1)) and ten class II substrates (1-aryloxy-3-nitro-2-propanone (4)) to furnish both enantiomers of the corresponding -nitro alcohols, with good-to-excellent conversions (up to >99%) and enantioselectivities (up to >99% ee) being achieved in most cases. To the best of our knowledge, KRED-mediated reduction of class II -nitro ketones (1-aryloxy-3-nitro-2-propanone (4)) is unprecedented. Select -nitro alcohols, including the synthetic intermediates of bioactive molecules (R)-tembamide, (S)-tembamide, (S)-moprolol, (S)-toliprolol and (S)-propanolol, were stereoselectively synthesized in preparative scale with 42% to 90% isolated yields, showcasing the practical potential of our developed system in organic synthesis. Finally, the advantage of using KREDs with known sequence was demonstrated by whole-cell catalysis, in which -nitro alcohol (R)-2k, the key synthetic intermediate of hypoglycemic natural product (R)-tembamide, was produced in a space-time yield of 178 g L-1 d(-1) as well as 95% ee by employing the whole cells of a recombinant E. coli strain coexpressing RasADH and glucose dehydrogenase as the biocatalyst.

About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Wang, ZX; Wu, XF; Li, ZN; Huang, ZD; Chen, F or concate me.. COA of Formula: C7H4Cl2O2

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocks. Recently I am researching about ACID ORANGE 7; PHOTOCATALYTIC DEGRADATION; AZO-DYE; VISIBLE-LIGHT; METHYL-ORANGE; WATER; OPTIMIZATION; OXIDATION; CARBON, Saw an article supported by the . Published in MAIK NAUKA/INTERPERIODICA/SPRINGER in NEW YORK ,Authors: Moradi, R; Ganjali, A. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid

In this paper, synthesized Fe3O4 nanoparticles applied as catalyst in photodegradation of Direct Red 23 (DR23) dye using photo-Fenton process in aqueous solution. The Fe3O4 nanoparticles were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR). Design of experiments (DOE) based on Taguchi approach was used. Analysis the response of each experiment was based Signal to Noise (S/N) ratio was calculated. The effective parameters for the degradation of dye were determined and optimized using Taguchi (L-9 (3(4))) orthogonal array experimental design method with four factors having three levels for each factor. The Taguchi approach showed that pH 3 (level 1), catalyst amount = 25 mg/L (level 2), H2O2 concentration = 15 ppm (level 3), and temperature = 35 degrees C (level 3) was optimum conditions for this process. The factor most influencing the process was determined using analysis of variance (ANOVA) method. The most significant factor in this process was pH. The interaction between pH x catalyst amount was the most influencing interaction. The percent (p (%)) of each factor on the degradation of dye was found to be in the following the order: pH (50.306%), catalyst amount (6.887%), H2O2 concentration (39.272%), and temperature (3.456%). The percentage contribution of factors in this process was found to be in the following the order: pH (0.332), catalyst amount (0.101), H2O2 concentration (0.291), and temperature (0.082). So first order reaction with k = 0.0472 min(-1) was observed for the photocatalytic degradation reaction.

Category: chlorides-buliding-blocks. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Moradi, R; Ganjali, A or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocks. In 2019 J AGR FOOD CHEM published article about PHYTOPHTHORA-CAPSICI; BLACK SHANK; OXATHIAPIPROLIN; STROBILURINS; METALAXYL; EFFICACY; DOCKING; CYP51 in [Wu, Qifan; Zhao, Bin; Fan, Zhijin; Guo, Xiaofeng; Yang, Dongyan; Zhang, Nailou; Yu, Bin; Zhou, Shuang; Zhao, Jiabao; Chen, Fan] Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China; [Fan, Zhijin] Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China in 2019, Cited 40. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

Oxathiapiprolin is one of the best active fungicides discovered for oomycetes control. To develop a fungicide candidate with a broad spectrum of activity, 22 new piperidinylthiazole derivatives were designed and synthesized. Compound 51 showed the best activity against Pseudoperonospora cubensis (Berk. et Curt.) Rostov and Phytophthora infestans in vivo with 100% and 80% of inhibition, respectively, at 1 mg/L, and 72.87% of field efficacy against P. cubensis at 1 g ai/667 m(2) validated these results. Compound 5i exhibited a broad spectrum of excellent activity against Sclerotinia sclerotiorum with EC50 = 0.30 mg/ L (>10 times more active than oxathiapiprolin and azoxystrobin in vitro), good activity against Botrytis cinerea, Cercospora arachidicola, and Gibberella zeae with EC50 of 14.54, 5.57, and 14.03 mg/L in vitro and against P. cubensis and P. infestans with 60% and 30% inhibition rates, respectively, at 1 mg/L in vivo. Mode of action studies by RNA sequencing analysis discovered oxysterol-binding protein (OSBP), chitin synthase (CHS1), and (1,3)-beta-glucan synthase (FKS2) as the potent target of 5i against S. sclerotiorum. Quenching studies validated that OSBP was the same target of both 5i and oxathiapiprolin; it was quenched by both of them. Our studies discovered isothiazole-containing piperidinylthiazole as an OSBP target-based novel lead for fungicide development.

About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Wu, QF; Zhao, B; Fan, ZJ; Guo, XF; Yang, DY; Zhang, NL; Yu, B; Zhou, S; Zhao, JB; Chen, F or concate me.. Category: chlorides-buliding-blocks

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

COA of Formula: C7H4Cl2O2. In 2019 J MED CHEM published article about 20S PROTEASOMES; CRYSTAL-STRUCTURE; IMMUNOPROTEASOME; SITES; YEAST; GENERATION; BORTEZOMIB; MECHANISM; SUBSTRATE; KNOWLEDGE in [Xin, Bo-Tao; de Bruin, Gerjan; Maurits, Elmer; Espinal, Christofer; Du, Yimeng; Janssens, Marissa; Florea, Bogdan I.; van der Marel, Gijsbert A.; Overkleeft, Herman S.] Leiden Inst Chem, Gorlaeus Labs, Einsteinweg 55, NL-2333 CC Leiden, Netherlands; [Xin, Bo-Tao; de Bruin, Gerjan; Maurits, Elmer; Espinal, Christofer; Du, Yimeng; Janssens, Marissa; Florea, Bogdan I.; van der Marel, Gijsbert A.; Overkleeft, Herman S.] Netherlands Prote Ctr, Einsteinweg 55, NL-2333 CC Leiden, Netherlands; [Huber, Eva M.; Heinemeyer, Wolfgang; Groll, Michael] Tech Univ Munich, Lehrstuhl Biochem, Dept Chem, Ctr Integrated Prot Sci, D-85748 Garching, Germany; [Driessen, Christoph] Kantonsspital St Gallen, Dept Hematol & Oncol, CH-9007 St Gallen, Switzerland; [Weyburne, Emily S.; Kisselev, Alexei F.] Geisel Sch Med Dartmouth, Dept Mol & Syst Biol, 1 Med Ctr Dr HB7936, Lebanon, NH 03756 USA; [Weyburne, Emily S.; Kisselev, Alexei F.] Geisel Sch Med Dartmouth, Norris Cotton Canc Ctr, 1 Med Ctr Dr HB7936, Lebanon, NH 03756 USA; [Kisselev, Alexei F.] Auburn Univ, Harrison Sch Pharm, Dept Drug Discovery & Dev, Auburn, AL 36849 USA in 2019, Cited 43. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

Subunit-selective proteasome inhibitors are valuable tools to assess the biological and medicinal relevance of individual proteasome active sites. Whereas the inhibitors for the beta 1c, beta 1i, beta 5c, and beta 5i subunits exploit the differences in the substrate-binding channels identified by X-ray crystallography, compounds selectively targeting beta 2c or beta 2i could not yet be rationally designed because of the high structural similarity of these two subunits. Here, we report the development, chemical synthesis, and biological screening of a compound library that led to the identification of the beta 2c- and beta 2i-selective-compounds LU-002c (4; IC50 beta 2c: 8 nM, IC50 beta 2i/beta 2c: 40-fold) and LU-002i (5; IC50 beta 2i: 220 nM, IC50 beta 2c/beta 2i: 45-fold), respectively. Co-crystal structures with beta 2 humanized yeast proteasomes visualize protein-ligand interactions crucial for subunit specificity. Altogether, organic syntheses, activity-based protein profiling, yeast mutagenesis, and structural biology allowed us to decipher significant differences of beta 2 substrate-binding channels and to complete the set of subunit-selective proteasome inhibitors.

About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Xin, BT; Huber, EM; de Bruin, G; Heinemeyer, W; Maurits, E; Espinal, C; Du, YM; Janssens, M; Weyburne, ES; Kisselev, AF; Florea, BI; Driessen, C; van der Marel, GA; Groll, M; Overkleeft, HS or concate me.. COA of Formula: C7H4Cl2O2

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Dai, ZH; Zhu, J; Wang, JH; Su, WB; Yang, FL; Zhou, QF in [Dai, Zonghao; Zhu, Jin; Wang, Jiahua; Su, Wenbo; Yang, Fulai; Zhou, Qingfa] China Pharmaceut Univ, Dept Organ Chem, State Key Lab Nat Med, Nanjing 210009, Jiangsu, Peoples R China published Phosphine-Catalyzed Chemoselective [4+3] Cycloaddition of Alminine Esters and beta ‘-acetoxy Allenoates for Divergent Synthesis of Azepines in 2020.0, Cited 96.0. Recommanded Product: 50-30-6. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Text. A general method for the synthesis of structural diversity and complexity of azepines from aldimine esters and beta ‘-acetoxy allenoates is reported. Under phosphine catalysis, a [4+3] cycloaddition for the formation of 1,3-dihydro-2H-azepine-2,2,4-tricarboxylates was achieved with broad substrate scope under mild reactions. A switchable process was given and a variety of important 2,3-dihydrochromeno[4,3-b]azepin-6(1H)-ones were selectively formed when the reaction was performed in the presence of Cs2CO3 and PPh3, which involved an intramolecular ester group migration and subsequent lactonization of 1,3-dihydro-2H-azepine-2,2,4-tricarboxylates. Besides easy handle process, high synthetic value of resulting products, it is worth to note that this work showed the novel example of 1,5-ethoxycarbonyl migration.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Dai, ZH; Zhu, J; Wang, JH; Su, WB; Yang, FL; Zhou, QF or concate me.. Recommanded Product: 50-30-6

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article A Strategy for Accessing Aldehydes via Palladium-Catalyzed C-O/C-N Bond Cleavage in the Presence of Hydrosilanes published in 2020.0. Recommanded Product: 50-30-6, Reprint Addresses Liu, TT; Zeng, Z (corresponding author), South China Normal Univ, Sch Chem, Guangzhou 510006, Peoples R China.; Zeng, Z (corresponding author), Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China.. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid

We report the catalytic reduction of both active esters and amides by selective C(acyl)-X (X=O, N) cleavage to access aldehyde functionality via a palladium-catalyzed strategy. Reactions are promoted by hydrosilanes as reducing reagents with good to excellent yields and with excellent chemoselectivity for C(acyl)-N and C(acyl)-O bond cleavage. Carboxylic acid C(acyl)-O bonds are activated by 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) to form triazine ester intermediates, which further react with hydrosilanes to yield aldehydes in one-pot two-step procedures. We demonstrate that C(acyl)-O cleavage/formylation offers higher yields and broader substrate scopes compared with C(acyl)-N cleavage under the same reaction conditions.

Recommanded Product: 50-30-6. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact He, ZY; Wang, ZJ; Ru, JX; Wang, YL; Liu, TT; Zeng, Z or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

COA of Formula: C7H4Cl2O2. Mandal, S; Saha, S; Jana, CK in [Mandal, Sumana; Saha, Subhajit; Jana, Chandan K.] Indian Inst Technol Guwahati, Dept Chem, Gauhati 780139, Assam, India published Diastereoselective and Reversed Regioselective Annulations of N-Alkyl Anilines to Julolidines and Lilolidines in 2020, Cited 89. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

A three-component annulation reaction of N-alkyl anilines, cyclic 1,3-dicarbonyl compounds, and aryl aldehydes to julolidines and lilolidines is reported. The 6 pi-electrocyclization enabled the annulation to proceed with reversed regioselectivity as compared with the annulation that occurs in the Povarov reaction. Both cyclic and acyclic N-alkyl anilines participated in the reaction to provide a wide range of julolidines and lilolidines as the single regio- and diastereoisomers in good to excellent yields.

COA of Formula: C7H4Cl2O2. About 2,4-Dichlorobenzoic acid, If you have any questions, you can contact Mandal, S; Saha, S; Jana, CK or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics