Tag: M.W=100-150

An article Chemical composition and antioxidant capacity of black pepper pericarp WOS:000546692300001 published article about PIPER-NIGRUM L.; OFF-FLAVOR COMPOUNDS; WHITE PEPPER; UNDESIRABLE ODORANTS; SPICES in [Lee, Joon-Goo] Minist Food & Drug Safety, Food Stand Div, Heungduk 28159, Cheongju, South Korea; [Chae, Young] Centumtech, Seoul 07566, South Korea; [Shin, Youngjae] Dankook Univ, Dept Food Engn, Cheonan 31116, Chungnam, South Korea; [Kim, Young-Jun] Seoul Natl Univ Sci & Technol, Dept Food Sci & Technol, Seoul 01811, South Korea in 2020.0, Cited 44.0. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8. Formula: C7H7Cl

Piper nigrumL. is a widely used spice because of its flavour and health effects. It is prepared as black and white pepper, according to the harvest time and inclusion of the outer skin. Pepper pericarp is usually considered waste when making white pepper. In this study, bioactive and flavour compounds and minerals in the pericarp of black pepper were determined to identify its applications. The pericarp contained total phenol, total flavonoid and piperine contents of 1421.95 +/- 22.35 mg GAE/100 g, 983.82 +/- 8.19 mg CE/100 g and 2352.19 +/- 68.88 mg/100 g, respectively. There were higher levels of total phenols and total flavonoids in the pericarp compared with black pepper and white pepper. Piperine content was lower in the pericarp than in black pepper. The principal monoterpene compounds in the pericarp were alpha-pinene (9.2%), 2-beta-pinene (14.3%), delta-3-carene (21.5%) anddl-limonene (18.8%), and the primary sesquiterpenes were alpha-copaene (5.1%) and caryophyllene (17.2%). The higher percentages of flavour compounds found in the pericarp would impart a more potent odour, and the pericarp exhibited higher minor and tiny differences based on electronic nose analysis. It had more minerals than black pepper and peeled black pepper.

Formula: C7H7Cl. About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Lee, JG; Chae, Y; Shin, Y; Kim, YJ or concate me.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Quality Control of 2-Chloro-6-methylaniline. Recently I am researching about VITRO PHARMACOLOGICAL CHARACTERIZATION; RELEASE; AGONIST; SCHIZOPHRENIA; DISCOVERY; TARGETS; SERIES; ACID, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [NSFC 21572011, 81573410, 31370741, 21272009]; Ministry of Science and Technology of ChinaMinistry of Science and Technology, China [2013CB531302]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Li, YH; Sun, LL; Yang, TY; Jiao, WX; Tang, JS; Huang, XM; Huang, ZZ; Meng, Y; Luo, LC; Wang, XT; Bian, XL; Zhang, F; Wang, KW; Sun, Q. The CAS is 87-63-8. Through research, I have a further understanding and discovery of 2-Chloro-6-methylaniline

A series of novel thiazolo[4,5-d]pyrimidin-7(6H)-ones (3aa-3eq) were designed, synthesized, and evaluated as the type I positive allosteric modulators of human alpha 7 nAChR expressed in Xenopus ooctyes by a two-electrode voltage clamp. The structure-activity relationship analysis identified the compound 3ea as a potent and efficacious PAM with the maximum activation effect of the alpha 7 current of over 1633% in the presence of acetylcholine (100 mu M) and an EC50 = 1.26 mu M. It is highly specific to alpha 7 nAChR over other subtypes of nAChR, 5-HT3A, NMDA, and GABA(A) receptors. Compound 3ea showed an elimination half-life of 10.8 +/- 1.5 h for 3 mg/kg, i.v., and 7.4 +/- 1.1 h for 60 mg/kg, i.g. in rat. It also exhibited sufficient blood-brain barrier penetration with no significant effect on hERG channel. Most importantly, compound 3ea dose-dependently (0.1-1 mg/kg, i.p.) reversed the prepulse inhibition deficit induced by MK-801 in the mouse schizophrenia model. X

Quality Control of 2-Chloro-6-methylaniline. About 2-Chloro-6-methylaniline, If you have any questions, you can contact Li, YH; Sun, LL; Yang, TY; Jiao, WX; Tang, JS; Huang, XM; Huang, ZZ; Meng, Y; Luo, LC; Wang, XT; Bian, XL; Zhang, F; Wang, KW; Sun, Q or concate me.

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Quality Control of 2-Chloro-6-methylaniline. In 2020 CHEM COMMUN published article about ORTHO-ACYLATION; 2H-INDAZOLES; FUNCTIONALIZATION; AZOXYBENZENES; CONDENSATION; AZOBENZENES; ANNULATION; ACCESS; MILD in [Jin, Guo-Qing; Gao, Wen-Xia; Zhou, Yun-Bing; Liu, Miao-Chang; Wu, Hua-Yue] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China in 2020, Cited 38. The Name is 2-Chloro-6-methylaniline. Through research, I have a further understanding and discovery of 87-63-8.

A straightforward and efficient method for the preparation of 2-aryl-2H-indazoles from ortho-alkyl substituted azoxybenzenes is presented. The reaction proceeds through base-catalyzed benzyl C-H deprotonation and cyclization to afford 2-aryl-2H-indazoles in good yields. This synthetic strategy can be applied to the construction of several fluorescent and bioactive molecules.

Quality Control of 2-Chloro-6-methylaniline. About 2-Chloro-6-methylaniline, If you have any questions, you can contact Jin, GQ; Gao, WX; Zhou, YB; Liu, MC; Wu, HY or concate me.

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sarmah, K; Mukhopadhyay, S; Maji, TK; Pratihar, S in [Sarmah, Kasturi; Mukhopadhyay, Subhamoy; Maji, Tarun K.; Pratihar, Sanjay] Tezpur Univ, Dept Chem Sci, Napaam 784028, Assam, India published Switchable Bifunctional Bistate Reusable ZnO-Cu for Selective Oxidation and Reduction Reaction in 2019.0, Cited 75.0. Safety of 1-Chloro-2-methylbenzene. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8.

Herein we disclosed the utilization of copper loaded zinc oxide (ZnO-Cu) for its stimuli (O-2/light) responsive switchable performance between its reduced (S-1) and oxidized (S-2) state for two antagonistic reactions, namely oxidation of alkyl arenes/heteroarenes to aldehydes/ketones and reduction of nitro arenes/heteroarenes corresponding amines. The two states of the catalyst showed its switchable performance as highly active and poorly active catalyst for oxidation and reduction, and both reactions could be turned off and on by changing the stimuli (light and O-2/N-2). The switching efficiency between the states and their relative reactivity were found to be consistent under variety of reaction conditions and remain unaltered irrespective of oxidation-reduction (or vice versa) sequence and substrates used in the reaction. The photo catalysts (S-1 and S-2) demonstrated good catalytic activity, multiple reusability, broad substrate scope, and reasonable functional group tolerance for both the reactions and probed its quality performance in a large-scale setup. The system was used in an assisted tandem catalysis setup for the synthesis of benzyl amines utilizing both oxidation and reduction reaction by stimuli responsive switching between the states of the catalyst.

About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Sarmah, K; Mukhopadhyay, S; Maji, TK; Pratihar, S or concate me.. Safety of 1-Chloro-2-methylbenzene

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Recommanded Product: 95-49-8. In 2020.0 ADV SYNTH CATAL published article about EFFICIENT; FUNCTIONALIZATION; NANOPARTICLE; HETEROARENES; MECHANISM; ARRAY in [Ohno, Aya; Sato, Takuma; Yamada, Yoichi M. A.] RIKEN, Ctr Sustainable Resource Sci, Wako, Saitama 3510198, Japan; [Mase, Toshiaki; Uozumi, Yasuhiro] Inst Mol Sci IMS, Okazaki, Aichi 4448787, Japan in 2020.0, Cited 49.0. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8.

The development of highly active and reusable supported catalysts for Suzuki-Miyaura coupling and catalytic C-H arylation is important for fundamental and applied chemistry, with these reactions being used to produce medical compounds and functional materials. Herein, we found that a mesoporous composite made of a linear poly(4-vinylpyridine) and tetrachloropalladate acted as a dual-mode catalyst for a variety of cross-coupling reactions, with both Pd nanoparticles and a Pd complex catalyst being observed under different conditions. The polyvinylpyridine-palladium composite1was readily prepared via the molecular convolution of poly(4-vinylpyridine) and sodium tetrachloropalladate to provide a hardly soluble polymer-metal composite. The Suzuki-Miyaura coupling and the C-H arylation of aryl chlorides and bromides with arylboronic acids, thiophenes, furans, benzene, and anisole proceeded in the presence of 0.004 mol% (40 mol ppm) to 1 mol% Pd of1to afford the corresponding coupling products in high yields. Furthermore, the catalyst was reused without an appreciable loss of activity. Pharmaceutical compounds and functional materials were synthesized via the coupling reactions. N(2)gas adsorption/desorption analysis indicated that the catalyst had a mesoporous nature, which played a crucial role in the catalysis. In the Suzuki-Miyaura couplings,in situgenerated palladium nanoparticles in the polymer matrix were catalytically active, while a polymeric Pd(II) complex was crucial in the C-H arylations. These catalytic species were investigated via XAFS, XPS, far-infrared absorption, and Raman spectroscopies, as well as DFT calculations.

About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Ohno, A; Sato, T; Mase, T; Uozumi, Y; Yamada, YMA or concate me.. Recommanded Product: 95-49-8

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Metal-free synthesis of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles via microwave-assisted synthesis pathway published in 2020. Application In Synthesis of 2-Chloro-6-methylaniline, Reprint Addresses Tung, TT (corresponding author), PHENIKAA Univ, Fac Pharm, Hanoi 12116, Vietnam.. The CAS is 87-63-8. Through research, I have a further understanding and discovery of 2-Chloro-6-methylaniline

A simple, efficient, and metal-free methodology for the preparation of 2-mercaptobenzothiazole and derivatives in excellent yields via microwave-assisted pathway is reported. Our condition provides a convenient protocol for the synthesis of a diverse collection of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles with a very simple purification process. This report provides an alternative protocol for fast access to the wide range of compounds for sequence synthesis and biological studies.

Application In Synthesis of 2-Chloro-6-methylaniline. About 2-Chloro-6-methylaniline, If you have any questions, you can contact Tung, TT; Huy, LX or concate me.

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An article Efficient synthesis of 2-aryl-2H-indazoles by base-catalyzed benzyl C-H deprotonation and cyclization WOS:000592062700009 published article about ORTHO-ACYLATION; 2H-INDAZOLES; FUNCTIONALIZATION; AZOXYBENZENES; CONDENSATION; AZOBENZENES; ANNULATION; ACCESS; MILD in [Jin, Guo-Qing; Gao, Wen-Xia; Zhou, Yun-Bing; Liu, Miao-Chang; Wu, Hua-Yue] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China in 2020, Cited 38. The Name is 2-Chloro-6-methylaniline. Through research, I have a further understanding and discovery of 87-63-8. Name: 2-Chloro-6-methylaniline

A straightforward and efficient method for the preparation of 2-aryl-2H-indazoles from ortho-alkyl substituted azoxybenzenes is presented. The reaction proceeds through base-catalyzed benzyl C-H deprotonation and cyclization to afford 2-aryl-2H-indazoles in good yields. This synthetic strategy can be applied to the construction of several fluorescent and bioactive molecules.

Name: 2-Chloro-6-methylaniline. About 2-Chloro-6-methylaniline, If you have any questions, you can contact Jin, GQ; Gao, WX; Zhou, YB; Liu, MC; Wu, HY or concate me.

Reference:
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2006/20879; (2006); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Recently I am researching about PSEUDOMONAS SP; XYLENE BTX; BIODEGRADATION KINETICS; COMPETITIVE-INHIBITION; WASTE-WATER; P-XYLENE; BENZENE; TOLUENE; 1,2,4-TRICHLOROBENZENE; 1,4-DICHLOROBENZENE, Saw an article supported by the Dong Thap University. Published in BMC in LONDON ,Authors: Nguyen, OT; Ha, DD. The CAS is 95-49-8. Through research, I have a further understanding and discovery of 1-Chloro-2-methylbenzene. Computed Properties of C7H7Cl

The cooperation of Bacillus subtilis strain DKT and Comamonas testosteroni KT5 was investigated for biofilm development and toluenes and chlorobenzenes degradation. Bacillus subtilis strain DKT and C. testosteroni KT5 were co-cultured in liquid media with toluenes and chlorobenzenes to determine the degradation of these substrates and formation of dual-species biofilm used for the degradation process. Bacillus subtilis strain DKT utilized benzene, mono- and dichlorinated benzenes as carbon and energy sources. The catabolism of chlorobenzenes was via hydroxylation, in which chlorine atoms were replaced by hydroxyl groups to form catechol, followed by ring fission via the ortho-cleavage pathway. The investigation of the dual-species biofilm composed of B. subtilis DKT and C. testosteroni KT5 (a toluene and chlorotoluene-degrading isolate with low biofilm formation) showed that B. subtilis DKT synergistically promoted C. testosteroni KT5 to develop biofilm. The bacterial growth in dual-species biofilm overcame the inhibitory effects caused by monochlorobenzene and 2-chlorotoluene. Moreover, the dual-species biofilm showed effective degradability toward the mixture of these substrates. This study provides knowledge about the commensal relationships in a dual-culture biofilm for designing multispecies biofilms applied for the biodegradation of toxic organic substrates that cannot be metabolized by single-organism biofilms.

About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Nguyen, OT; Ha, DD or concate me.. Computed Properties of C7H7Cl

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An article Aging of microplastics affects their surface properties, thermal decomposition, additives leaching and interactions in simulated fluids WOS:000517760200002 published article about ENVIRONMENTAL-SAMPLES; DENSITY POLYETHYLENE; HUMAN HEALTH; TOXICITY; PIGMENTS; BEHAVIOR; IDENTIFICATION; COMPOSITES; ORGANISMS; PYROLYSIS in [Luo, Hongwei; Zhao, Yaoyao; Li, Yu; Xiang, Yahui; He, Dongqin; Pan, Xiangliang] Zhejiang Univ Technol, Coll Environm, Key Lab Microbial Technol Ind Pollut Control Zhej, Hangzhou 310014, Peoples R China in 2020.0, Cited 69.0. Product Details of 95-49-8. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8

Most microplastics (MPs) have undergone extensive aging in the environment. Aged MPs exhibit different physical and chemical properties from unaged ones. Here, we studied the effects of accelerated aging on the characteristics and pyrolysis of commercial pigmented MPs, as well as pigments leaching and their interactions in simulated gastric and intestinal fluids of mammals. We report that the carbonyl index, surface area, and color change of MPs increased after aging treatment. Cracks and fragmentation of MPs facilitated the accessibility of light and oxygen to internal layer and therefore accelerated the aging process. TGA/GC-MS analysis showed that the high temperature resistance of MN decreased after aging. Thermal decomposition of pigments and polyethylene occurred in temperature ranges of 340-406 degrees C and 406-550 degrees C, respectively. Mono (di)-alkenes and saturated alkanes were the thermal decomposition products of polyethylene. Aging of MPs also caused an increased release of pigments and prolonged aging time led to more release in simulated fluids. Pigments would result in fluorescence quenching of the enzymes through binding interactions once they were released from MPs into simulated fluids. Charge neutralization and polymer bridging accounted for the formation of pigment-enzyme complexes and flocs. These novel findings will allow us to better assess how aging process affects the characteristics, leaching, and toxicity of MPs. (C) 2020 Published by Elsevier B.V.

About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Luo, HW; Zhao, YY; Li, Y; Xiang, YH; He, DQ; Pan, XL or concate me.. Product Details of 95-49-8

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocks. In 2021.0 TETRAHEDRON LETT published article about SELECTIVE INHIBITORS; TANDEM REACTION; H BONDS; METAL; 2-ACYLBENZOTHIAZOLES; BENZOTHIAZOLE; CYCLIZATION; KETONES; BASE; 2-AROYLBENZOTHIAZOLES in [Lu, Qi; Sun, Xiao-Tong; Kong, Yao-Lei; Liu, Jin-Chuan; Chen, Bo; Weng, Jian-Quan] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China in 2021.0, Cited 41.0. The Name is 1-Chloro-2-methylbenzene. Through research, I have a further understanding and discovery of 95-49-8.

An efficient Selectfluor-oxidative protocol was developed for the direct C2-arylacylation of 2H-benzothiazoles via the radical reaction of 2H-benzothiazoles with methyl arenes. Selectfluor can effectively promote the oxidative cross-coupling without an external catalyst. This arylacylation reaction tolerates a wide range of functional groups affording 28 examples of the arylacylated products in 39-81% yield. (C) 2021 Elsevier Ltd. All rights reserved.

About 1-Chloro-2-methylbenzene, If you have any questions, you can contact Lu, Q; Sun, XT; Kong, YL; Liu, JC; Chen, B; Weng, JQ or concate me.. Category: chlorides-buliding-blocks

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics