Tag: 800-900

Product Details of 172222-30-9In 2021 ,《Selective Ring-Opening Allene Metathesis: Polymerization or Ruthenium Vinylidene Formation》 was published in ACS Macro Letters. The article was written by Neary, William J.; Sun, Yunyan; Moore, Jeffrey S.. The article contains the following contents:

Selective ring-opening allene metathesis polymerization (ROAlMP) and ruthenium vinylidene formation from 1,2-cyclononadiene (1) by simple catalyst selection are discussed. Grubbs second-generation catalyst (G2) favors the formation of an alkylidene leading to the ROAlMP of (1). Grubbs first-generation catalyst (G1) favors vinylidene formation and prevents the homopolymerization of (1) even at elevated temperatures Isolation and characterization of poly(1) by NMR anal. and MALDI-TOF confirms the generation of a well-defined polyallene that exhibits good thermal stability (TD ca. 390°C) and fluorescent properties. Ring-opening metathesis polymerization (ROMP) of a highly strained norbornene derivative (NBE-iPr) at 80°C using the ruthenium vinylidene generated from (1) is also investigated. The discovery of ROAlMP allows for the simple access of well-defined polyallenes from com. available catalysts and will ultimately guide structure-property determinations of polyallenes. In the part of experimental materials, we found many familiar compounds, such as Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Product Details of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Product Details of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Formula: C43H72Cl2P2RuIn 2020 ,《Helix stabilization by stapled N-capping box》 was published in Bioorganic Chemistry. The article was written by Pham, Thanh K.; Kim, Young-Woo. The article contains the following contents:

The N-capping box is a distinct helix-stabilizing motif frequently found in proteins. In this study, we examined a ruthenium-mediated intramol. backbone to side chain macrocyclization as a rigidified mimicry of the N-capping box. Exptl. data indicate that the 15-membered macrocycle formed by a hept-4-enoyl staple, which directly tethers the α-amino group of N1 residue and the α-carbon of N3 residue, is highly effective in stabilizing helical structures of short peptides. In addition to this study using Benzylidenebis(tricyclohexylphosphine)dichlororuthenium, there are many other studies that have used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Formula: C43H72Cl2P2Ru) was used in this study.

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Formula: C43H72Cl2P2Ru

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Blanco, Christian O.; Nascimento, Daniel L.; Fogg, Deryn E. published their research in Organometallics in 2021. The article was titled 《Routes to High-Performing Ruthenium-Iodide Catalysts for Olefin Metathesis: Ligand Lability Is Key to Efficient Halide Exchange》.Related Products of 172222-30-9 The article contains the following contents:

Clean, high-yielding routes are described to Ru-diiodide catalysts that were recently shown to enable high productivity in olefin metathesis. For the 2nd-generation Grubbs and Hoveyda catalysts (GII: RuCl2(H2IMes)(PCy3)(:CHPh); HII: RuCl2(H2IMes)(:CHAr), Ar = C6H4-2-OiPr), slow salt metathesis is shown to arise from the low lability of the ancillary PCy3 or ether ligands, which retards access to the four-coordinate intermediate required for efficient halide exchange. To exploit the lability of the 1st-generation catalysts, the diiodide complex RuI2(PCy3)(:CHAr) HI-I2 was prepared by treating Grubbs I (RuCl2(PCy3)2(:CHPh), GI) with NaI, H2C:CHAr (1a), and a phosphine-scavenging Merrifield iodide (MF-I) resin. Subsequent installation of H2IMes or cyclic (alkyl)(amino)carbene (CAAC) ligands afforded the 2nd-generation iodide catalysts in good to excellent yields. Given the incompatibility of the nitro group with a free carbene, the iodo-Grela catalyst RuI2(H2IMes)(:CHAr’) (nG-I2: Ar’ = C6H3-2-OiPr-4-NO2) was instead accessed by sequential salt metathesis of GI with NaI, installation of H2IMes, and finally cross-metathesis with the nitrostyrenyl ether H2C:CHAr’ (1b), with MF-I as the phosphine scavenger. The bulky iodide ligands improve the selectivity for macrocyclization in ring-closing metathesis. In the experiment, the researchers used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Related Products of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Related Products of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Introduction of Triptycene with a Particular Substitution Pattern into Polymer Chains Can Dramatically Improve the Structural and Rheological Properties》 was written by Ishiwari, Fumitaka; Okabe, Gen; Kajitani, Takashi; Fukushima, Takanori. Formula: C43H72Cl2P2RuThis research focused ontriptycene substitution polymer chain dramatically improve rheol. The article conveys some information:

Although a large number of polymers that contain triptycene units in the main chains have been developed, no polymer design using 1,8-substituted triptycene has been reported to date. In this study, we investigated the properties of linear homo- and copolymers obtained by ring-opening polymerization of a triptycene monomer bearing a macrocyclic olefin linked at its 1,8-position and its copolymerization with cyclooctene, resp. We found that the introduction of triptycene with this substitution pattern leads to nanoscale mol. ordering, thereby greatly improving the phys. properties of the polymers. The key to this remarkable behavior of 1,8-substituted triptycene-containing polymers is the formation of a particular two-dimensional assembly of the triptycene units by nested hexagonal packing, which aligns one-dimensionally while folding the polymer chains into a well-defined layered structure. The polymer design using 1,8-substituted triptycene can be applied to other polymers, unless their main chain contains functional groups capable of a strong intermol. interaction such as hydrogen bonding. In the experiment, the researchers used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Formula: C43H72Cl2P2Ru)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Formula: C43H72Cl2P2Ru

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2022,Estrada, Alexander L.; Wang, Leyong; Bhuvanesh, Nattamai; Hampel, Frank; Gladysz, John A. published an article in Organometallics. The title of the article was 《Syntheses, Structures, Reactivities, and Dynamic Properties of Gyroscope-like Complexes Consisting of Rh(CO)(X) or Rh(CO)2(I) Rotators and Cage-like Trans Aliphatic Dibridgehead Diphosphine Stators》.Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium The author mentioned the following in the article:

Square planar (4c) was prepared from trans-Rh(CO)(Cl)[P((CH2)6CH:CH2)3]2 by a C:C metathesis/hydrogenation sequence (41%). Additions of NaBr, NaI, or KSCN give the substitution pseudohalide products (X = Br/I/-NCS, 5c/6c/7c, 97-44%). Additions of ZnPh2, MeLi, or NaBH4 give Ph, Me complexes (R = Ph/Me, 8c/9c, ∼94-89%) or hydride complex (10c, 99%). Reactions with BrCCl3 or CO give the octahedral or trigonal bipyramidal addition products (11c, 97%) or (12c, ∼98%). The crystal structures of 5c, 6c, 8c, and 10c are determined These and other data were used to calculate the dimensions of the rotators and void spaces of the diphosphine cages, aiding the interpretation of dynamic properties. Specifically, 4c-6c and 9c-10c exhibit a single set of seven CH213C NMR signals at room temperature, although three sets of seven are expected from symmetry (facile 360° Rh(CO)(X) rotation); 7c-8c exhibit two sets of seven signals with a ∼ 2:1 area ratio (∼90° Rh(CO)(X) rotation); 11c exhibits three sets of seven signals (no Rh(CO)(Cl)(Br)(CCl3) rotation). The barrier to Rh(CO)2(I) rotation in 12c is bounded as higher than that of Rh(CO)(I) rotation in 6c, but the rotamers preferentially interconvert via CO dissociation/addition Reaction of 4c and excess PMe3 gives trans-Rh(CO)(Cl)(PMe3)2 (72%) and the dibridgehead diphosphine P((CH2)14)3P (58%). The latter reacts with [(OC)2Rh(μ-Cl)]2 to regenerate 4c (58%). In the experiment, the researchers used many compounds, for example, Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2022,Takebayashi, Satoshi; Iron, Mark A.; Feller, Moran; Rivada-Wheelaghan, Orestes; Leitus, Gregory; Diskin-Posner, Yael; Shimon, Linda J. W.; Avram, Liat; Carmieli, Raanan; Wolf, Sharon G.; Cohen-Ofri, Ilit; Sanguramath, Rajashekharayya A.; Shenhar, Roy; Eisen, Moris; Milstein, David published an article in Nature Catalysis. The title of the article was 《Iron-catalyzed ring-opening metathesis polymerization of olefins and mechanistic studies》.Related Products of 172222-30-9 The author mentioned the following in the article:

The olefin metathesis reaction is among the most widely applicable catalytic reactions for carbon-carbon double bond formation. Currently, Mo- and Ru-carbene catalysts are the most common choices for this reaction. It has been suggested that an iron-based catalyst would be a desirable economical and biocompatible substitute of the Ru catalysts; however, practical solutions in this regard are still lacking. Here, we report the discovery and mechanistic studies of three-coordinate iron(II) catalysts for ring-opening metathesis polymerization of olefins. Remarkably, their reactivity enabled the formation of polynorbornene with stereoregularity and high mol. weight (>107 g mol-1). The polymerization in the presence of styrene revealed cross metathesis reactivity with iron catalysts. Mechanistic studies suggest the possible role of metal-ligand cooperation in formation of the productive catalyst. This work opens the door to the development of iron complexes that can be economical and biocompatible catalysts for olefin metathesis reactions. In the part of experimental materials, we found many familiar compounds, such as Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Related Products of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Related Products of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Unusual redshift due to selective hydrogen bonding between F- ion and sensor motif: a naked eye colorimetric sensor for F- ions in an aqueous environment》 was published in Materials Advances in 2020. These research results belong to Singha, Jyotirlata; Samanta, Tapendu; Shunmugam, Raja. Category: chlorides-buliding-blocks The article mentions the following:

Naked-eye detection of anions is a challenging but useful technique. In this study, two novel colorimetric monomeric sensors based on highly selective 2,4-dinitrophenylhydrazine were designed, synthesized, and employed as a selective ratiometric optical sensor for F- ion detection via the naked eye. The anion recognition properties were investigated via a pattern of color change as well as changes in absorbance signaling maxima. Sensor mols. were characterized by 1H NMR, 13CNMR, HRMS, and FTIR spectroscopy. Selectivity towards F- ions was attributed to the capability of H-bonding interaction of N-H bonds, which was determined by 1H NMR titration, 19F NMR titration, and UV-vis spectroscopic titration The association constants of 0.263 × 106 M-1 (compound 4) and 6.4988 × 106 M-1 were calculated using the Benesi-Hildebrand equation from UV-vis spectroscopic anal. The limit of detection (LOD) for both monomeric sensors was 68.182 nM (compound 4) and 72.341 nM (compound 9) and for the polymeric sensor, it was 18.98157 nM (compound 11). Job′s plot anal. revealed the existence of 1 : 1 complex formation of F- ions with both monomeric sensor mols. The same colorimetric response and selectivity properties were exhibited by the norbornene-based homopolymer of the polymeric sensor mol. towards F- ions. In the experiment, the researchers used many compounds, for example, Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Category: chlorides-buliding-blocks)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Total and formal syntheses of fostriecin》 was written by Dong, Gao; Li, Bohui; O’Doherty, George A.. Quality Control of Benzylidenebis(tricyclohexylphosphine)dichlororutheniumThis research focused ontotal formal synthesis fostriecin. The article conveys some information:

Two formal syntheses and one total synthesis of fostriecin (1) have been achieved, as well as, the synthesis of its related congener dihydro-dephospho-fostriecin. All the routes use the Sharpless dihydroxylation to set the absolute stereochem. at C-8/9 positions and a Leighton allylation to set the C-5 position of the natural product. In the formal syntheses a Noyori transfer hydrogenation of an ynone was used to set the C-11 position while the total synthesis employed a combination of asym. dihydroxylation and Pd-π-allyl reduction to set the C-11 position. Finally in the total synthesis, a trans-hydroboration of the C-12/13 alkyne was used in combination with a Suzuki cross coupling to establish the Z,Z,E-triene of fostriecin (1). The experimental part of the paper was very detailed, including the reaction process of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Quality Control of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Quality Control of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ozer, Halenur; Arslan, Dilan; Ozturk, Bengi Ozgun published an article in 2021. The article was titled 《Dehydrogenative alcohol coupling and one-pot cross metathesis/dehydrogenative coupling reactions of alcohols using Hoveyda-Grubbs catalysts》, and you may find the article in New Journal of Chemistry.Application In Synthesis of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium The information in the text is summarized as follows:

In this study, in situ formed ruthenium hydride species that were generated from Grubbs type catalysts are used as efficient catalysts for dehydrogenative alc. coupling and sequential cross-metathesis/dehydrogenative coupling reactions. The selectivity of Grubbs first generation catalysts (G1, I) in dehydrogenative alc. coupling reactions can be tuned for the ester (octyl octanoate) formation in the presence of weak bases, while the selectivity can be switched to the β-alkylated alc. (2-hexyyl-1-decanol) formation using strong bases. The performance of Hoveyda-Grubbs 2nd generation catalyst (HG2) was improved in the presence of tricyclohexylphosphine for the selective synthesis of ester derivatives RC(O)OR1 (R = heptyl, Ph, dec-9-en-1-yl, etc.; R1 = H, octyl, Bn, etc.) and with γ-butyrolactone weak and strong bases in quant. yields. Allyl alc. was used as self and cross-metathesis substrate for the HG2 catalyzed sequential cross-metathesis/dehydrogenative alc. coupling reactions to obtain γ-butyrolactone and long-chain ester derivatives in quant. yields. After reading the article, we found that the author used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Application In Synthesis of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Application In Synthesis of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2022,Buchowicz, Wlodzimierz; Gunka, Piotr A.; Buchalski, Piotr; Piszcz, Michal; Bus, Sylwia; Mrozowicz, Michal; Mazur, Maria; Wasilewski, Rafal published an article in Organometallics. The title of the article was 《E/Z Switchable Ring-Closing Metathesis in 1,1′-Bis(but-3-enyl)ferrocenes: Synthesis and Characterization of Axially Chiral ansa[6]-Ferrocenes》.Computed Properties of C43H72Cl2P2Ru The author mentioned the following in the article:

Ansa[6]-ferrocenes were obtained through the Ru-catalyzed ring-closing olefin metathesis in 1,1′-bis(but-3-enyl)ferrocenes. The stereoselectivity of this reaction depended on the structure of substrates, i.e., mixtures of (E) and (Z) isomers were obtained for alkyl-substituted 3a-3d while (Z)-isomers only for aryl-substituted 3e and 3f. The ansa[6]-ferrocenes are axially chiral in the solid state according to single-crystal x-ray anal. In the case of Me-substituted derivative 4a, spontaneous resolution of the racemate was observed during crystallization The solution properties of (E) and (Z) isomers are remarkably different; the latter displays inequivalence of the two formally identical parts of the mol. at low temperatureBenzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Computed Properties of C43H72Cl2P2Ru) was used in this study.

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Computed Properties of C43H72Cl2P2Ru

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics