Koetz, Joachim et al. published their research in Nanomaterials in 2020 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Synthetic Route of C25H46ClN

The effect of surface modification of gold nanotriangles for surface-enhanced raman scattering performance was written by Koetz, Joachim. And the article was included in Nanomaterials in 2020.Synthetic Route of C25H46ClN The following contents are mentioned in the article:

A review. A surface modification of ultraflat gold nanotriangles (gold nanotriangles) with different shaped nanoparticles is of special relevance for surface-enhanced Raman scattering (SERS) and the photo-catalytic activity of plasmonic substrates. Therefore, different approaches are used to verify the flat platelet morphol. of the gold nanotriangles by oriented overgrowth with metal nanoparticles. The most important part for the morphol. transformation of the gold nanotriangles is the coating layer, containing surfactants or polymers. By using well established gold nanotriangles stabilized by a dioctyl sodium sulfosuccinate bilayer, different strategies of surface modification with noble metal nanoparticles are possible. On the one hand undulated superstructures were synthesized by in situ growth of hemispherical gold nanoparticles in the polyethyleneimine (PEI)-coated AOT bilayer of the AuNTs. On the other hand spiked gold nanotriangles were obtained by a direct reduction of Au3+ ions in the dioctyl sodium sulfosuccinate double layer in presence of silver ions and ascorbic acid as reducing agent. Addnl., crumble topping of the smooth gold nanotriangles can be realized after an exchange of the dioctyl sodium sulfosuccinate bilayer by hyaluronic acid, followed by a silver-ion mediated reduction with ascorbic acid. Furthermore, a decoration with silver nanoparticles after coating the dioctyl sodium sulfosuccinate bilayer with the cationic surfactant benzylhexadecyldimethylammonium chloride (BDAC) can be realized. In that case the UV-absorption of the undulated Au@Ag nanoplatelets can be tuned depending on the degree of decoration with silver nanoparticles. Comparing the Raman scattering data for the plasmon driven dimerization of 4-nitrothiophenol (4-NTP) to 4,4′-dimercaptoazobenzene (DMAB) one can conclude that the most important effect of surface modification with a 75 times higher enhancement factor in SERS experiments becomes available by decoration with gold spikes. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Synthetic Route of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Synthetic Route of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gunther, Nereus W. IV et al. published their research in Food Control in 2018 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Computed Properties of C25H46ClN

Quaternary ammonium compounds with multiple cationic moieties (multiQACs) provide antimicrobial activity against Campylobacter jejuni was written by Gunther, Nereus W. IV;Abdul-Wakeel, Aisha;Reichenberger, Erin R.;Al-Khalifa, Saleh;Minbiole, Kevin P. C.. And the article was included in Food Control in 2018.Computed Properties of C25H46ClN The following contents are mentioned in the article:

Recently developed quaternary ammonium compounds (QACs) possessing multiple cationic moieties, referred to as multiQACs, were tested with strains of Campylobacter jejuni to determine their potential as antimicrobial compounds against this important foodborne pathogen. Eight multiQACs were tested against a cocktail of six C. jejuni strains isolated from environmental and clin. sources. The resulting reductions in C. jejuni numbers mediated by the multiQACs were compared to the reductions produced by the application of four com. available QACs, each of which bears a single cation. Multiple concentrations and exposure times were utilized for all compounds The compounds which yielded the maximum C. jejuni reductions at the lowest concentrations and applied over the shortest exposure times were judged to be the most successful. Of the eight multiQACs investigated, four demonstrated reductions in C. jejuni numbers superior to the com. QACs; these four are biscationic, and two of them bear an addnl. uncharged nitrogen atom. The remaining four multiQACs, which contain three or four cations, did not produce reductions in bacterial numbers comparable to com. QACs in the timeframes tested. At the intermediary compound concentration (0.05 mM) and exposure time (5 min) the most effective multiQACs (PQ-12,12 and 12(3)0(3)12) on average killed over 99% of the Campylobacter cells present while the best com. compound at those parameters (cetyl pyridinium chloride, CPC) only killed on average 84.56% of the Campylobacter cells. At the highest compound concentration tested (0.1 mM) and shortest exposure time (1 min), the same two biscationic multiQACs averaged mean percent reductions of Campylobacter cell numbers around 99.5% while CPC at the same concentration/exposure only managed a percent reduction of 91.3%. The biscationic multiQACs demonstrate the potential for providing a new group of antimicrobial compounds superior to current com. available QACs in their effectiveness against C. jejuni. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Computed Properties of C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Computed Properties of C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Elizarova, Iuliia S. et al. published their research in Journal of Colloid and Interface Science in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 122-18-9

Layer-by-layer encapsulated nano-emulsion of ionic liquid loaded with functional material for extraction of Cd2+ ions from aqueous solutions was written by Elizarova, Iuliia S.;Luckham, Paul F.. And the article was included in Journal of Colloid and Interface Science in 2017.Recommanded Product: 122-18-9 The following contents are mentioned in the article:

Ionic liquids can serve as an environmentally-friendly replacement for solvents in emulsions, therefore they are considered suitable to be used as an emulsified medium for various active materials one of which are extractors of metal ions. Increasing the extraction efficiency is considered to be one of the key objectives when working with such extraction systems. One way to improve the extraction efficiency is to increase the contact area between the extractant and the working ionic solution This can be accomplished by creating a nano-emulsion of ionic liquid containing such an extractant. Since emulsification of ionic liquid is not always possible in the sample itself, there is a necessity of creating a stable emulsion that can be added externally and on demand to samples from which metal ions need to be extracted We propose a method of fabrication of a highly-stable extractant-loaded ionic liquid-in-water nano-emulsion via a low-energy phase reversal emulsification followed by continuous layer-by-layer polyelectrolyte deposition process to encapsulate the nano-emulsion and enhance the emulsion stability. Such a multilayered stabilized nano-emulsion was tested for extraction of Cd2+ and Ca2+ ions in order to determine its extraction efficiency and selectivity. It was found to be effective in the extraction of Cd2+ ions with near 100% cadmium removal, as well as being selective since no Ca2+ ions were extracted The encapsulated emulsion was removed from samples post-extraction using two methods – filtration and magnetic separation, both of which were shown to be viable under different circumstances – larger and mech. stronger capsules could be removed by filtration, however magnetic separation worked better for both smaller and bigger capsules. The long-term stability of nano-emulsion was also tested being a very important characteristic for its proposed use: it was found to be highly stable after four months of storage time. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Recommanded Product: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kanoje, Bharatkumar et al. published their research in Physical Chemistry Chemical Physics in 2018 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C25H46ClN

Synergism and aggregation behavior in an aqueous binary mixture of cationic-zwitterionic surfactants: physico-chemical characterization with molecular simulation approach was written by Kanoje, Bharatkumar;Padshala, Shailesh;Parikh, Jigisha;Sahoo, Suban K.;Kuperkar, Ketan;Bahadur, Pratap. And the article was included in Physical Chemistry Chemical Physics in 2018.COA of Formula: C25H46ClN The following contents are mentioned in the article:

Aqueous interactions between a cationic surfactant benzyl dimethylhexadecylammonium chloride (BDHAC) and alkyldimethylammoniopropane sulfonates (CnDAPS) based three zwitterionic surfactants n = 10, 12, and 14 (abbreviated as C10DAPS, C12DAPS and C14DAPS, resp.) were studied using tensiometry, and fluorescence spectrophotometry techniques. The critical micelle concentration degree of synergism and various other parameters such as interaction parameter (β), activity coefficients (fm) and interfacial parameters such as surface pressure (πCMC), packing parameter (P), surface excess concentration (Γmax), surface tension at CMC (γCMC), and min. area per mol. (Amin) were evaluated using the Regular Solution Theory (RST) of mixed systems. The results indicate a strong dependency on the mixed system and their composition For the quant. prediction, the mol. architecture of the surfactants in mixed systems and their synergistic interactions were investigated by computational simulation using Spartan’14 V1.1.8. The structural optimization results obtained were found to be in good agreement with the estimations made using RST. The reduction in surface tension indicates a certain efficiency in mixed micelle formation owing to electrostatic attraction between the cationic and zwitterionic surfactants. In addition, the binary surfactant systems evaluated by Maeda’s approach infer the mixed micelles are thermodynamically stable. The aggregation number (Nagg) appeared to be larger at the composition point where the efficiency of mixed micelle formation is greatest. The strength of the interaction between BDHAC and CnDAPS followed the order: C14DAPS > C12DAPS > C10DAPS indicating a greater synergism at 0.25 molar ratio of zwitterionic surfactants to cationic surfactants in the aqueous solution at 303.15 K. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9COA of Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Altamirano, Marcela S. et al. published their research in Journal of Photochemistry and Photobiology, A: Chemistry in 2016 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Photophysics and photochemistry of mercurochrome in reverse micelles was written by Altamirano, Marcela S.;Grassano, Micaela E.;Bertolotti, Sonia G.;Previtali, Carlos M.. And the article was included in Journal of Photochemistry and Photobiology, A: Chemistry in 2016.Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride The following contents are mentioned in the article:

The photophysics of the xanthene dye 2′,7′-Dibromo-5′-(hydroxymercurio)fluorescein disodium salt (merbromine, mercurochrome) (MCr) was studied in reverse micelles (RMs) of sodium 1,4-bis (2-ethylhexyl) sulfosuccinate (AOT) and benzylhexadecyldimethylammonium chloride (BHDC). In the reverse micellar media both the absorption and emission spectra of the dye present a red shift with respect to water. It is concluded that MCr in both reverse micellar systems is localized in the interface. In BHDC due to the pos. charge at the interface and the neg. charge of the dye, it remains anchored to the interface irresp. of the water content of the RMs. On the other hand in the case of the neg. interface of AOT the photophys. properties tend to those in homogeneous water solution as the water content increases. For small size AOT RMs the dye resides in the interface co-micellizing with the surfactant, although more exposed to water than in the case of BHDC. Special interest was assigned to the effect of confinement on the triplet state properties. The triplet state decay kinetics and absorption spectra were determined by laser flash photolysis. The triplet lives longer in RMs than in homogeneous solvents. The compartmentalization of the dye precludes the auto-quenching which shorts the lifetime in homogeneous solvents. Furthermore, the quenching by electron donors and acceptors was investigated. Two aliphatic amines were used as electron donors. The hydrophilic triethanolamine (TEOA) is localized in the water pool, and the triplet quenching is more efficient than in homogeneous solvents. The apparent quenching rate constant for TEOA in AOT is one order of magnitude higher than BHDC. On the other hand the quenching by dipropylamine (DPA) which is located in the bulk organic solvent is much less efficient. The quenching by TEOA in RMs can be understood in terms of an exchange mechanism between micelles. As electron acceptor 1,4-benzoquinone (BQ) was employed, and the value in BHDC is two orders of magnitude higher than in AOT. These divergences most likely arise from different partitions of the quenchers in the reverse micellar systems. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application In Synthesis of N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Nong, Yingyi et al. published their research in Applied Clay Science in 2021 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks

Effects of cationic modifier type on the structure and morphology of organo-montmorillonite and its application properties in a high-temperature white oil system was written by Nong, Yingyi;Sun, Jinlong;Fu, Meng;Chen, Huiwen;Zhang, Zepeng. And the article was included in Applied Clay Science in 2021.Category: chlorides-buliding-blocks The following contents are mentioned in the article:

Three types (eight modifiers with three radical groups) of cationic modifiers aliphatic quaternary ammonium salts (AlQAS), aromatic quaternary ammonium salts (ArQAS), and polyoxyethylene quaternary ammonium salts (PoQAS), were used to modify montmorillonite (Mt) and prepare cationic-organo-montmorillonites (COMt). COMt was characterized by X-ray diffraction, SEM, contact angle, thermogravimetry, optical microscopy, gel volume, viscosity, and thixotropy to explore modifier type effects on the structure, morphol., and properties of COMt, as well as investigate the application properties in white oil system. The results show that eight cationic modifiers all entered the Mt. layer to form intercalated COMt. The modifier type significantly influences the structure, morphol., and properties of the obtained COMt and the application properties in white oil system. The basal spacing of PoQAS COMt (d001 = 4.33 nm ∼ 5.28 nm) was the larger than ArQAS COMt (d001 = 3.14 nm ∼ 3.60 nm) and AlQAS COMt (d001 = 2.91 nm ∼ 3.66 nm). The morphologies of the three types of COMt lamella were all in a loose state. The order of COMt lamellar loosening degree with the same chain length was PoQAS COMt > ArQAS COMt > AlQAS COMt. The thermal stability and lipophilicity of the COMt powders were consistent with the morphol. results. In the white oil system at 180°C, XRD results showed that the thermal stability of PoQAS COMt was the best (maintaining the structure of PoQAS COMt and no Mt. generation), followed by ArQAS COMt, and AlQAS COMt had the worst thermal stability. The viscosity and thixotropy of three types COMt was ArQAS COMt better than PoQAS COMt and AlQAS COMt, PoQAS COMt better than AlQAS COMt. Research also showed that the steric hindrance, electropositivity of the modifier mol., and modifiers’ thermal stability are pos. related to the thermal stability of COMt in white oil. This work provides a basis and other ideas in understanding the relationships between radical groups types, the structures of quaternary ammonium salts, the thermal stability of COMt, and selecting and developing new modifiers. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Category: chlorides-buliding-blocks).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Roy, Arpita et al. published their research in Journal of Colloid and Interface Science in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C25H46ClN

Influence of bile salt on vitamin E derived vesicles involving surface active ionic liquid and conventional cationic micelle was written by Roy, Arpita;Kundu, Sangita;Dutta, Rupam;Sarkar, Nilmoni. And the article was included in Journal of Colloid and Interface Science in 2017.Formula: C25H46ClN The following contents are mentioned in the article:

This study has been actually performed with the aim to develop vitamin E derived vesicles individually from a surface active ionic liquid (1-Hexadecyl-3-Methylimidazolium chloride ([C16mim]Cl)) and a common cationic amphiphile (benzyldimethylhexadecylammonium chloride (BHDC)) and also to investigate their consequent breakdown in presence of bile salt mol. From this study, it is revealed that the rotational motion of coumarin 153 (C153) mol. is hindered as the vitamin E content is increased in the individual micellar solution of [C16mim]Cl and BHDC. The extent of enhancement in rotational relaxation time is more pronounced in case of [C16mim]Cl-vitamin E solutions than in the BHDC-vitamin E vesicular aggregates which confirms the greater rigidity of the former vesicular system than the later one. Moreover, the effect of bile salt in the vitamin E forming vesicular assemblies have also been unravelled. It is found that the large area occupancy by the steroidal backbone of the bile salt plays a crucial role towards the enlargement of the average surfactant head group area. This results in disintegration of the vesicles composed of vitamin E and consequently, vesicles are transformed into mixed micellar aggregates. From the anisotropy measurement it is found that the rotational motion of C153 is more hindered in the [C16mim]Cl/BHDC-NaCh mixed micelles compared to that inside the individual vesicles. The fluorescence correlation spectroscopic (FCS) study also confirms that the mixed micelles have a more compact structure than that of the [C16mim]Cl-vitamin E and BHDC-vitamin E vesicles. Altogether, the micelle to vesicle transition involving any vitamin and their disruption by bile salt would be an interesting investigation both from the view point of basic colloidal chem. and towards the generation of new drug delivery vehicle due to their unique microenvironment. Therefore, in future, these systems can be utilized as vehicle for the transport and as well as delivery of drugs and as probable reactor in nanomaterial synthesis. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Singh, Priya et al. published their research in Chemistry – A European Journal in 2019 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.SDS of cas: 122-18-9

Modulation of kinetic pathways of enzyme-substrate interaction in a microfluidic channel was written by Singh, Priya;Mukherjee, Dipanjan;Singha, Subhankar;Das, Ranjan;Pal, Samir Kumar. And the article was included in Chemistry – A European Journal in 2019.SDS of cas: 122-18-9 The following contents are mentioned in the article:

Enzyme-mediated catalysis is attributed to enzyme-substrate interactions, with models such as “induced fit” and “conformational selection” emphasizing the role of protein conformational transitions. The dynamic nature of the protein structure, thus, plays a crucial role in mol. recognition and substrate binding. As large-scale protein motions are coupled to water motions, hydration dynamics play a key role in protein dynamics, and hence, in enzyme catalysis. Here, microfluidic techniques and time-dependent fluorescence Stokes shift (TDFSS) measurements are employed to elucidate the role of nanoscopic water dynamics in the interaction of an enzyme, α-Chymotrypsin (CHT), with a substrate, Ala-Ala-Phe-7-amido-4-methylcoumarin (AMC) in the cationic reverse micelles of benzylhexadecyldimethylammonium chloride (BHDC/benzene) and anionic reverse micelles of sodium bis(2-ethylhexyl)sulfosuccinate (AOT/benzene). The kinetic pathways unraveled from the microfluidic setup are consistent with the “conformational selection” fit for the interaction of CHT with AMC in the cationic reverse micelles, whereas an “induced fit” mechanism is indicated for the anionic reverse micelles. In the cationic reverse micelles of BHDC, faster hydration dynamics (≈550 ps) aid the pathway of “conformational selection”, whereas in the anionic reverse micelles of AOT, the significantly slower dynamics of hydration (≈1600 ps) facilitate an “induced fit” mechanism for the formation of the final enzyme-substrate complex. The role of water dynamics in dictating the mechanism of enzyme-substrate interaction becomes further manifest in the neutral reverse micelles of Brij-30 and Triton X-100. In the former, the faster water dynamics aid the “conformational selection” pathway, whereas the significantly slower dynamics of water mols. in the latter are conducive to the “induced fit” mechanism in the enzyme-substrate interaction. Thus, nanoscopic water dynamics act as a switch in modulating the pathway of recognition of an enzyme (CHT) by the substrate (AMC) in reverse micelles. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9SDS of cas: 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.SDS of cas: 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Seguin, Ryan P. et al. published their research in Chemical Research in Toxicology in 2019 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.COA of Formula: C25H46ClN

Metabolism of Benzalkonium Chlorides by Human Hepatic Cytochromes P450 was written by Seguin, Ryan P.;Herron, Josi M.;Lopez, Vanessa A.;Dempsey, Joseph L.;Xu, Libin. And the article was included in Chemical Research in Toxicology in 2019.COA of Formula: C25H46ClN The following contents are mentioned in the article:

Benzalkonium chlorides (BACs) are widely used as disinfectants in cleaning products, medical products, and the food processing industry. Despite a wide range of reported toxicities, limited studies have been conducted on the metabolism of these compounds in animal models and none in human-derived cells or tissues. In this work, we report on the metabolism of BACs in human liver microsomes (HLM) and by recombinant human hepatic cytochrome P 450 (CYP) enzymes. BAC metabolism in HLM was NADPH-dependent and displayed apparent half-lives that increased with BAC alkyl chain length (C10 < C12 < C14 < C16), suggesting enhanced metabolic stability of the more lipophilic, longer chain BACs. Metabolites of d7-benzyl labeled BAC substrates retained all deuteriums and there was no evidence of N-dealkylation. MS/MS fragmentation of BAC metabolites confirmed oxidation occurs on the alkyl chain region. Major metabolites of C10-BAC were identified as ω-hydroxy-, (ω-1)-hydroxy-, (ω,ω-1-diol-, ω-1)-ketone-, and ω-carboxylic acid-C10-BAC by LC-MS comparison with synthetic standards In a screen of hepatic CYP isoforms, recombinant CYP2D6, CYP4F2, and CYP4F12 consumed substantial quantities of BAC substrates and produced the major microsomal metabolites. The use of potent pan-CYP4 inhibitor HET0016, the specific CYP2D6 inhibitor quinidine, or both confirmed major contributions of CYP4- and CYP2D6-mediated metabolism in the microsomal disappearance of BACs. Kinetic characterization of C10-BAC metabolite formation in HLM demonstrated robust Michaelis-Menten kinetic parameters for ω-hydroxylation (Vmax = 380 pmol/min/mg, Km = 0.69μM) and (ω-1)-hydroxylation (Vmax = 126 pmol/min/mg, Km = 0.13μM) reactions. This work illustrates important roles for CYP4-mediated ω-hydroxylation and CYP2D6/CYP4-mediated (ω-1)-hydroxylation during the hepatic elimination of BACs, an environmental contaminant of emerging concern. Furthermore, we demonstrate that CYP-mediated oxidation of C10-BAC mitigates the potent inhibition of cholesterol biosynthesis exhibited by this short-chain BAC. Furthermore, we demonstrate that CYP-mediated oxidation of C10-BAC mitigates the potent inhibition of cholesterol biosynthesis exhibited by this short-chain BAC. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9COA of Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.COA of Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dang, Hua et al. published their research in Analytical Methods in 2017 | CAS: 122-18-9

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.COA of Formula: C25H46ClN

One-step extraction prior to two-step detection by ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) to determine different groups of antibacterial agents in infant disposable hygiene products was written by Dang, Hua;Liu, Donghong;Hou, Xiangchang;Wu, Yuluan;Wang, Bin;Dong, Hao;Xian, Yanping. And the article was included in Analytical Methods in 2017.COA of Formula: C25H46ClN The following contents are mentioned in the article:

One-step extraction prior to a two-step detection method based on UHPLC-MS/MS was developed to determine seven quaternary ammonium salts (QACs), three isothiazolinone antibacterial agents and seven phenolic antibacterial agents in infant disposable hygiene products. Samples were ultrasonically extracted by acetonitrile; the extraction solution was directly used to sep. seven QACs on a hydrophilic chromatog. column (HILIC column) by isocratic elution (0.1% formic acid acetonitrile and 10 mmol L-1 ammonium acetate solution as the mobile phases). QACs were then detected in multiple reaction monitoring (MRM) of MS/MS under an electro-spray ionization source in pos. mode (ESI+). For the remaining ten analytes, the extraction solution was dried by nitrogen gas blowing and re-dissolved with acidulated methanol water solution Then they were separated on a C18 chromatog. column with gradient elution program using methanol and water as mobile phases. Finally, ten analytes were simultaneously ionized by using a electro-spray source in pos. and neg. modes and acquisition was achieved in MRM. The developed methods were validated in terms of the method limit of detection and quantitation (MLOD and MLOQ), matrix effects, recovery and precision. Results indicated that favorable linear relations (r > 0.997) were obtained over the selected concentration ranges of 0.1-50μg L-1, 1.0-500μg L-1 and 50-2000μg L-1 for QACs, isothiazolinone antibacterial agents and phenolic antibacterial agents, resp. The MLODs of the three groups of antibacterial agents were 0.8μg kg-1, 1.5-6.5μg kg-1 and 200-500μg kg-1, resp. Recoveries were calculated at three concentration levels spiked in neg. paper diaper samples and the values were found between 83.7% and 112% with relative standard deviation (RSD) values less than 13% for intra-day precision (n = 6) and less than 16% for inter-day precision (n = 5). The developed and validated methods were successfully applied to determine the concentrations of antibacterial agents in real samples and QACs and isothiazolinone antibacterial agents were detected in several samples. These methods are rapid, sensitive and suitable for the determination of antibacterial agents in infant disposable hygiene products and some other similar products. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9COA of Formula: C25H46ClN).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.COA of Formula: C25H46ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics