Tag: 200-300

Preparation of polysulfone support for higher-performance reverse osmosis membranes was written by Takeuchi, Kenji;Cruz-Silva, Rodolfo;Fujishige, Masatsugu;Yanagisawa, Naomi;Kitazawa, Hidenori;Maeda, Jun;Endo, Morinobu. And the article was included in Journal of Environmental Chemical Engineering in 2022.Recommanded Product: Trimesoylchloride This article mentions the following:

We prepared a polysulfone (PSU) support by applying a coating of a PSU-N,N-dimethylformamide (DMF) solution on 91μm thick nonwoven and then set it in water (the phase inversion process). The prepared PSU-substrate sheet was 280 mm wide and 10 m long. We then investigated the effects of the preparation conditions (i.e., the concentration of the PSU-DMF solution and the coating thickness) on the water permeability of the resulting PSU support. The thickness of the PSU layer increased almost linearly with the increase in the coating thickness, and the water permeability decreased monotonically with the increase in the PSU layer’s thickness. A bubble point anal. revealed that the pore size dia. of the membranes was approx. 20-60 nm, depending on the PSU-DMF solution’s concentration Using these PSU membranes as the support, we prepared a reverse-osmosis (RO) membrane, the active layer of which consisted of aromatic polyamide (PA) that contained carbon nanotubes. The salt rejection rate 99.7% and water permeability at 0.56 L m^-2 h^-1 bar^-1 were achieved at 5.5 MPa for a 3.2% NaCl solution with the RO membrane, the support of which was prepared from a 17.0% PSU-DMF solution In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Recommanded Product: Trimesoylchloride).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Recommanded Product: Trimesoylchloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gemini-mediated self-disinfecting surfaces to address contact transmission of infectious diseases was written by Kim, MinJu;Linstadt, Roscoe T. H.;Ahn Ando, Kollbe;Ahn, Jinsoo. And the article was included in Langmuir in 2022.HPLC of Formula: 3386-33-2 This article mentions the following:

According to both the Center for Disease Control and the World Health Organization, contact transmission is the primary transmission route of infectious diseases worldwide. Usually, this is mitigated by a schedule of repeated regular sanitization, yet surfaces are easily re-contaminated in the interim between cleanings. One solution to this problem is to generate self-disinfecting surfaces that can display sustained virucidal/antimicrobial properties against pathogens that settle upon them. Quaternary ammonium organosilicon compounds are ideal candidates to achieve this; cationic surfactants are safe and well-established surface disinfectants, while organosilanes are used broadly to form durable coatings with altered surface properties on many different materials. Despite their potential to circumvent the disadvantages of traditional disinfection methods, extant com. available quaternary ammonium silanes do not display comparable efficacy to the standard surface disinfectants, nor have their resp. coatings been demonstrated to meet the Environmental Protection Agency’s guidelines for residual/extended efficacy. Inspired by the powerful surface activity of double-headed “gemini” surfactants, here, we present gemini-diquaternary silanes (GQs) with robust residual germicidal efficacy on various surfaces by incorporating a second cationic “head” to the structure of a conventional monoquaternary ammonium silane (MQ). Aqueous solutions of GQs were tested in suspension- and surface-antimicrobial assays against an array of pathogens, including Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). GQ performance was benchmarked against the common disinfectants, ethanol, hydrogen peroxide, hypochlorite, as well as MQ. Solutions of GQs were efficacious when used for immediate disinfection (>10⁶-fold reduction in 15 s). Addnl., GQs were demonstrated to impart durable self-disinfecting properties to a variety of porous and nonporous surfaces, effective after repeated cycles of abrasion and repeated contaminations, and with superior coating ability and activity (>10⁸ higher activity) than that of MQs. GQs as surface treatments show great promise to overcome the limitations of traditional disinfectants in preventing the spread of infectious diseases. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2HPLC of Formula: 3386-33-2).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.HPLC of Formula: 3386-33-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Effective antimony removal from wastewaters using polymer modified sepiolite: Isotherm kinetic and thermodynamic analysis was written by Saleh, Tawfik A.;Tuzen, Mustafa;Sar, Ahmet. And the article was included in Chemical Engineering Research and Design in 2022.COA of Formula: C9H3Cl3O3 This article mentions the following:

Sepiolite was modified with polymer consisting of ethylenediamine(EDA)-trimesoyl chloride (TMC) to produce a highly effective sorbent for antimony (III) (Sb(III)) adsorption from aquatic solutions The EDA-TMC polymeric branches were grafted onto the surface of sepiolite by polymerization The surface morphol. and the main adsorptive chem. groups of the developed S/EDA-TMC sorbent were characterized by SEM, EDX, BET, and FTIR, anal. methods. The impact of the batch adsorption conditions on the adsorption performance was systematically studied by conducting a factorial design anal. While Langmuir and Freundlich isotherm models were employed with the non-linear equations to the removal data and the removal capacity of the prepared composite was estimated as 210.1 mg g^-1 based on the Langmuir due to relatively high correlation. The kinetic investigation results displayed that the pseudo-second-order kinetic model was well appropriate for characterizing Sb(III) removal mechanism. Also, thermodn. findings verified that the Sb(III) removal onto the composite adsorbent progressed exothermically and spontaneously with temperature increasing from 24° to 55°C. Besides, the produced adsorbent demonstrated still appreciated adsorption/desorption yield (80/76%) after the 7th cycle. Accordingly, the fabricated S/EDA-TMC material can be evaluated as a powerful sorbent in the cleaning of aqueous solutions containing Sb(III) pollutants. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1COA of Formula: C9H3Cl3O3).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C9H3Cl3O3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

High performance polyamide TFC reverse osmosis membrane fabricated on co-deposition hydrophilic modified polyethylene substrate was written by Huang, Wei;Wang, Ziyin;Xie, Fei;Ding, Hanzhuo;Li, Wenxuan;Liang, Xiaokang;Ma, Xiaohua;Xu, Zhenliang. And the article was included in Desalination in 2022.SDS of cas: 4422-95-1 This article mentions the following:

The separation performance of polyamide (PA) thin film composite (TFC) membrane is critically influenced by the substrates. Numerical models and exptl. studies suggest that substrates with high porosity comprising small pores can effectively improve membrane performance. Here we report that a com. polyethylene (PE) micro-porous membrane with high porosity was chosen as substrate for fabricating PA TFC membrane. The PE substrate was modified by co-depositing the copolymers of gallic acid and γ-aminopropyltriethoxysilane to improve its bulk hydrophilicity. The porosity, pore size, morphol. and chem. properties of the modified PE substrates were characterized. The resultant PA TFC-PE membrane had a favorable water permeance of 2.33 ± 0.06 L m^-2 h^-1 bar^-1 as well as a high NaCl rejection of 99.0 ± 0.4% because of the suitable porosity, pore size and hydrophilicity for interfacial polymerization reaction. Our work is expected to provide an efficient way for the modification of hydrophobic porous membrane for fabricating PA TFC membrane. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1SDS of cas: 4422-95-1).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).SDS of cas: 4422-95-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Lewis acid-controlled reactions of zirconacyclopentadienes with isocyanates and isothiocyanates. One-pot three- or four-component synthesis of multiply substituted iminocyclopentadienes and butadiene-tethered 1,6-bisamides and electrophilic cyclization was written by Hu, Qiaoshu;Lu, Jiang;Wang, Congyang;Wang, Chao;Xi, Zhenfeng. And the article was included in Tetrahedron in 2007.Recommanded Product: 2,4-Dichlorophenylisothiocyanate This article mentions the following:

Multiply substituted zirconacyclopentadienes including bicyclic zirconacyclopentadienes and zirconaindenes reacted with isocyanates and isothiocyanates in the presence of Lewis acids to afford iminocyclopentadienes and conjugated 1,6-bisamides, depending on the nature of Lewis acids, isocyanates, and isothiocyanates used. Only in the presence of BF₃ could iminocyclopentadienes be obtained in high isolated yields when zirconacyclopentadienes were treated with isocyanates. On the contrary, BF₃ could not mediate the reaction of zirconacyclopentadienes with isothiocyanates. For the reactions of zirconacyclopentadienes with isothiocyanates, EtAlCl₂ was found effective to generate iminocyclopentadienes as the products. Interestingly, however, for the reactions of zirconacyclopentadienes with isocyanates, EtAlCl₂ was found to work very differently from BF₃. Instead of iminocyclopentadienes, conjugated 1,6-bisamides and conjugated mono-amides were obtained as products in high isolated yields from the reactions of zirconacyclopentadienes with isocyanates, depending on the substituents of isocyanates. The reaction path and products could be controlled by Lewis acids. As a demonstration of the usefulness of thus obtained unsaturated bisamides, electrophilic cyclization using acids, NBS, and I₂ was carried out. Electrophilic cyclization of multisubstituted conjugated 1,6-bisamide derivatives afforded cyclic iminoethers in excellent yields with perfect selectivity. Only one of the amide groups took part in the electrophilic cyclization. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Recommanded Product: 2,4-Dichlorophenylisothiocyanate).

2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 2,4-Dichlorophenylisothiocyanate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Design, synthesis and biological activities of sorafenib derivatives as antitumor agents was written by Yao, Jianwen;He, Zuopeng;Chen, Jing;Sun, Wei;Fang, Hao;Xu, Wenfang. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2012.Name: 2,4-Dichlorophenylisothiocyanate This article mentions the following:

A series of novel sorafenib derivatives was designed and synthesized in high yields using various substituted anilines, and their antiproliferative activities against HCT116, PC-3 and MDA-MB-231 cell lines were also evaluated and described. All compounds exhibited potent antiproliferative activity against HCT116 and PC-3 cells with IC₅₀ = 2.8-52.0 and 2.2-45.6 μM; compounds I [R = Et, cyclopropyl] demonstrated competitive antiproliferative activities to sorafenib against all three cancer cell lines; the cytotoxicity of compound I [R = cyclohexyl] is more potent than that of sorafenib. Some compounds were chosen for further evaluation of the anti-angiogenesis activity, and showed the inhibition of sprout formation from aortic ring ex vivo. The structures of all the newly synthesized compounds were determined by ¹H NMR, ¹³C NMR and HRMS. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Name: 2,4-Dichlorophenylisothiocyanate).

2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: 2,4-Dichlorophenylisothiocyanate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Thermoanalytical characterization of herbal drugs from Poincianella pyramidalis in different particle sizes was written by Guimaraes, Geovani Pereira;Santos, Ravely Lucena;Brandao, Deysiane Oliveira;Cartaxo-Furtado, Nathalia Alexandra de Oliveira;Cavalcanti, Airlla Laana de Medeiros;Macedo, Rui Oliveira. And the article was included in Journal of Thermal Analysis and Calorimetry in 2018.Quality Control of 1-Chlorooctadecane This article mentions the following:

Poincianella pyramidalis (Tul.) L. P. Queiroz, known as “catingueira,” is a typical species of Caatinga and used in Brazilian folk medicine as anti-inflammatory, antipyretic, diuretic and expectorant. Pharmacol. analyses confirmed his activity as anti-inflammatory, antimicrobial and in gastrointestinal disorders. This paper aimed to perform a thermoanal. characterization of the herbal drugs obtained from P. pyramidalis leaves in different particle sizes. The leaves were dried, pulverized and separated into different granulometric ranges: 50-100, 100-200, 200-400 and <400 mesh. The samples were characterized by thermogravimetry (TG) at different atmospheres and heating rates, determination of the kinetic degradation parameters by Ozawa model, DTA (DTA), pyrolysis coupled to gas chromatog. interfaced with mass spectrometry (Pyr-GC/MS) and multivariate anal. TG curves of the samples showed the presence of six thermal decomposition events, with greater mass loss (25.91-35.66%) in the range of 247-398°C. The thermal degradation proved to be a reaction of zero order, with a decrease in enthalpy and frequency factor with decreasing the granulometric range. DTA curves showed three exothermic events, with peaks around 350, 460 and 490°C, with variation in enthalpy values. With the Pyr-GC/MS were evidenced different profiles according to the temperature Principal component anal. of pyrolysis data from samples at different temperatures was able to represent the total variability within the first two principal components, revealing differences between the granulometric ranges. The anal. and statistical techniques used were able to trace characteristic profiles of the herbal drugs, elucidating the differences in each granulometric range. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Quality Control of 1-Chlorooctadecane).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Quality Control of 1-Chlorooctadecane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Studies on the novel pyridine sulfide containing SDH based heterocyclic amide fungicide was written by Hua, Xuewen;Liu, Wenrui;Su, Yanyan;Liu, Xinghai;Liu, Jingbo;Liu, Nannan;Wang, Guiqing;Jiao, Xueqin;Fan, Xiaoyi;Xue, Chenmeng;Liu, Yi;Liu, Ming. And the article was included in Pest Management Science in 2020.HPLC of Formula: 59237-53-5 This article mentions the following:

BACKGROUND : Succinate dehydrogenase (SDH) has been identified as one of the most significant targets for fungicide discovery. To date, 23 com. SDH inhibitor (SDHI) fungicides have been approved for plant protection since the first launch of carboxin in 1966, and extensively applied to combat destructive plant fungi. RESULTS : In this project, 20 novel pyridine sulfide derivatives containing SDH-based heterocyclic amide fungicide were designed, synthesized, and characterized by proton NMR (¹H-NMR), carbon-13 (¹³C)-NMR and high-resolution mass spectrometry (HRMS). In vitro fungicidal activity experiment, the target compound I-1 displayed excellent inhibitory rates against the common agricultural pathogens with half maximal effective concentration (EC₅₀) values of 5.2 to 39.8μg mL^-1. The in vivo fungicidal activities demonstrated that the compound I-1 could effectively prevent Botrytis cinerea from infecting tomato and cucumber leaves with the preventative rates of 67% and 50%. The mitochondrial membrane potential detection, SDH enzyme assay and the mol. docking simulation revealed that the mechanism of action of the compound I-1 and the relevant interactions with the target enzyme may be similar to those of the control fluopyram. CONCLUSION : The biol. activity screening and validation of mechanism of action indicated that the compound I-1 could be identified as a potential SDH inhibitor for further study. 2020 Society of Chem. Industry. In the experiment, the researchers used many compounds, for example, Methyl 6-chloro-5-nitronicotinate (cas: 59237-53-5HPLC of Formula: 59237-53-5).

Methyl 6-chloro-5-nitronicotinate (cas: 59237-53-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.HPLC of Formula: 59237-53-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Potent Non-Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors from Genetic Engineering of Streptomyces hygroscopicus was written by Menzella, Hugo G.;Tran, Thomas-Toan;Carney, John R.;Lau-Wee, Janice;Galazzo, Jorge;Reeves, Christopher D.;Carreras, Christopher;Mukadam, Sophie;Eng, Sara;Zhong, Ziyang;Timmermans, Pieter B. M. W. M.;Murli, Sumati;Ashley, Gary W.. And the article was included in Journal of Medicinal Chemistry in 2009.SDS of cas: 34662-36-7 This article mentions the following:

Inhibition of the protein chaperone Hsp90 is a promising new approach to cancer therapy. We describe the preparation of potent non-benzoquinone ansamycins. One of these analogs, generated by feeding 3-amino-5-chlorobenzoic acid to a genetically engineered strain of Streptomyces hygroscopicus, shows high accumulation and long residence time in tumor tissue, is well-tolerated upon i.v. dosing, and is highly efficacious in the COLO205 mouse tumor xenograft model. In the experiment, the researchers used many compounds, for example, 3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7SDS of cas: 34662-36-7).

3-Chloro-5-nitrobenzoic acid (cas: 34662-36-7) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).SDS of cas: 34662-36-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Examining the structure-activity relationship of benzopyran-based inhibitors of the hypoxia inducible factor-1 pathway was written by Ferguson, Jalisa;De Los Santos, Zeus;Devi, Narra;Van Meir, Erwin;Zingales, Sarah;Wang, Binghe. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2017.Name: 2,4-Dimethoxybenzene-1-sulfonyl chloride This article mentions the following:

Many forms of solid tumor have a characteristic feature known as hypoxia, which describes a low or nonexistent presence of oxygen in the cellular microenvironment. This decrease in oxygen causes activation of the hypoxia inducible factor (HIF) pathway, which activates the transcription of many genes that cause cell proliferation, metastasis, increased glycolysis and angiogenesis. Increased HIF expression has been linked with poor patient prognosis, increased malignancy, and therapeutic resistance. Previous work in the lab has identified I and II as inhibitors of the HIF pathway, specifically as disrupters of the p300-HIF-1α complex formation. A library of sulfonamide analogs has been designed and synthesized with the intent of examining the SAR of this series of compounds and improving potency and physicochem. properties as compared with lead compounds I and II. At the end, the authors have achieved a thorough understanding of the structural features critical for future optimization work. In the experiment, the researchers used many compounds, for example, 2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2Name: 2,4-Dimethoxybenzene-1-sulfonyl chloride).

2,4-Dimethoxybenzene-1-sulfonyl chloride (cas: 63624-28-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Name: 2,4-Dimethoxybenzene-1-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics