Tag: 200-300

Interlayered thin-film nanocomposite membrane with synergetic effect of COFs interlayer and GQDs incorporation for organic solvent nanofiltration was written by Li, Shuxuan;Yin, Yating;Liu, Shaoxiao;Li, Honghai;Su, Baowei;Han, Lihui;Gao, Xueli;Gao, Congjie. And the article was included in Journal of Membrane Science in 2022.Product Details of 4422-95-1 This article mentions the following:

The separation performance of current organic solvent nanofiltration (OSN) membranes are still not satisfied. In this work, an ultra-thin TpHz covalent organic frameworks (COFs) interlayer was in situ constructed in advance on polyimide substrate, then an ultra-thin polyamide separation layer incorporated with amino-functionalized graphene quantum dots (af-GQDs) was constructed via interfacial polymerization (IP). A high performance interlayered thin-film nanocomposite (iTFN) OSN membrane with integrally covalent bonding structure, ultra-thin and ultra-smooth surface was obtained after post crosslinking and activation. The effect of ultra-low concentrations for the polyamide reaction monomers, the COFs monomer Tp and the doped af-GQDs nanoparticle reveals that they could help to form a very thin (7-8 nm in thickness) and defect-free skin layer with very smooth surface (about 2.7 nm in roughness). The iTFN OSN membrane shows excellent solvent permeance and solute selectivity, with an ethanol permeance reaching 97.6 L m^-2 h^-1 MPa^-1 and an RDB rejection higher than 99%. After a 180 h long-term filtration with 100 mg L^-1 RB/DMF solution, it remained an RB rejection of higher than 99%, demonstrating its superior resistance to strong polar solvent. Our work paves a unique way for the fabrication of novel OSN membrane with both in situ constructed nanomaterials interlayer and nanomaterials incorporated in skin layer. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Product Details of 4422-95-1).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Product Details of 4422-95-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Benzothiazepine CGP37157 Analogues Exert Cytoprotection in Various in Vitro Models of Neurodegeneration was written by Martinez-Sanz, Francisco J.;Lajarin-Cuesta, Rocio;Moreno-Ortega, Ana J.;Gonzalez-Lafuente, Laura;Fernandez-Morales, Jose C.;Lopez-Arribas, Raquel;Cano-Abad, Maria F.;Rios, Cristobal de los. And the article was included in ACS Chemical Neuroscience in 2015.COA of Formula: C11H14ClNO2 This article mentions the following:

Mitochondria regulate cellular Ca²⁺ oscillations, taking up Ca²⁺ through its uniporter and releasing it through the mitochondrial sodium/calcium exchanger. The role of mitochondria in the regulation of Ca²⁺ cycle has received much attention recently, as it is a central stage in neuronal survival and death processes. Over the last decades, the 4,1-benzothiazepine CGP37157 has been the only available blocker of the mitochondrial sodium/calcium exchanger, although it targets several other calcium transporters. We report the synthesis of 4,1-benzothiazepine derivatives with the goal of enhancing mitochondrial sodium/calcium exchanger blockade and selectivity, and the evaluation of their cytoprotective effect. The compound 4c presented an interesting neuroprotective profile in addition to an important blockade of the mitochondrial sodium/calcium exchanger. The use of this benzothiazepine could help to understand the physiol. functions of the mitochondrial sodium/calcium exchanger. In addition, we hypothesize that a moderate blockade of the mitochondrial sodium/calcium exchanger would provide enhanced neuroprotection in neurons. In the experiment, the researchers used many compounds, for example, tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6COA of Formula: C11H14ClNO2).

tert-Butyl (4-chlorophenyl)carbamate (cas: 18437-66-6) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C11H14ClNO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and biological screening of some new 5,7-dihydro-4H-thieno[2,3-c]pyran-3-yl containing 1,2,4-triazoles, 1,3,4-oxadiazoles, and 1,3-thiazoles was written by Jadhav, Ranjana K.;Akolkar, Hemant N.;Nikumbh, Arun B.;Karale, Bhausaheb K.. And the article was included in Indian Journal of Heterocyclic Chemistry in 2021.Computed Properties of C7H3Cl2NS This article mentions the following:

Some new 5,7-dihydro-4H-thieno[2,3-c]pyran thiosemicarbazides I [R¹ = H, Cl, OMe, OCF₃, Me, Et, R³ = Cl, H, F] were synthesized from 5,7-dihydro-4H-thieno[2,3-c]pyran-3-carbohydrazide and aryl isothiocyanates in ethanol. Compounds I, on refluxing with 1N NaOH, gave (thieno[2,3-c]pyranyl)(phenyl)-4H-1,2,4-triazole-3-thiols II, and with 4N NaOH in the presence of I₂/KI gave (thieno[2,3-c]pyranyl)-N-phenyl-1,3,4-oxadiazol-2-amines III. When I were reacted with 2-bromo-1-(4-fluorophenyl)ethanone to obtain (11Z)-(thiazol-2(3H)-ylidene)-4H-thieno[2,3-c]pyran-3-carbohydrazides IV. The structures of the synthesized compounds were confirmed by using spectral techniques. The compounds were also screened for their antifungal and antibacterial activity. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Computed Properties of C7H3Cl2NS).

2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Computed Properties of C7H3Cl2NS

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Visible-Light Responsive Sucrose-Containing Macrocyclic Host for Cations was written by Sokolowska, Patrycja;Dabrowa, Kajetan;Jarosz, Slawomir. And the article was included in Organic Letters in 2021.Safety of (Chloromethanetriyl)tribenzene This article mentions the following:

Chiral photoresponsive host 1 was prepared by a high-yield Cs₂CO₃-templated macrocyclization. Trans-1 transforms into long-lived cis-1 (25 days) upon irradiation with green light, and the backward transformation is triggered by blue light. Both isomers prefer potassium among alkali metal cations, and cis-1 binds cations stronger than trans-1 (K_cis/K_trans â‰?4.1). ¹H NMR titration experiments as well as d. functional theory studies reveal that sucrose ring oxygen residues and azobenzene nitrogen atoms in 1 contribute to cation coordination. In the experiment, the researchers used many compounds, for example, (Chloromethanetriyl)tribenzene (cas: 76-83-5Safety of (Chloromethanetriyl)tribenzene).

(Chloromethanetriyl)tribenzene (cas: 76-83-5) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Safety of (Chloromethanetriyl)tribenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and characterization of novel fluorinated thiazolyl 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazoles by conventional and non-conventional methods was written by Akolkar, H. N.;Karale, B. K.;Randhavane, P. V.;Dalavi, N. R.. And the article was included in Indian Journal of Chemistry in 2017.Recommanded Product: 2,4-Dichlorophenylisothiocyanate This article mentions the following:

A series of novel fluorinated thiazolyl thiosemicarbazides I (R¹ = R² = H, R³ = F; R¹ = R³ = H, R² = Me; R¹ = R³ = Cl, R² = H, etc.), 1,3,4-thiadiazoles II and 1,2,4-triazoles III have been synthesized by using conventional and non-conventional methods. The compounds 1,3-thiazoles IV have been synthesized from thiosemicarbazide I by using conventional method. The structures of synthesized compounds have been confirmed with the help of spectral techniques. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Recommanded Product: 2,4-Dichlorophenylisothiocyanate).

2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 2,4-Dichlorophenylisothiocyanate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sulfoquinovosylglyceryl ether, a new group of ether lipids from lake ball-forming green alga Aegagropilopsis moravica (family Pithophoraceae) was written by Oku, Naoya;Hasada, Atsumi;Kimura, Kenji;Honoki, Hideharu;Katsuta, Ryo;Yajima, Arata;Nukada, Tomoo;Ishigami, Ken;Igarashi, Yasuhiro. And the article was included in Chemistry – An Asian Journal in 2021.Name: (Chloromethanetriyl)tribenzene This article mentions the following:

Ether lipids are a minor group of glycerolipids but widespread in nature, playing a vital function as membrane lipids, signalling mols., or buoyant material. We have discovered sulfoquinovosylchimyl alc. (1), a sulfonate-substituted glyceroglycolipid, from a lake ball-forming green alga Aegagropilopsis moravica (family Pithophoraceae), with the guidance of antimicrobial activity. The structure of 1, including absolute configurations of all sterogenic centers, was established by extensive NMR anal., chem. degradation studies, and finally by total synthesis. Lipid 1 is an ether variant of a lyso-form of sulfoquinovosyldiacylglycerol, a chloroplast-specific membrane lipid, and thus represents a new lipid class, sulfoquinovosylglyceryl ether. A high occurrence of mobile life form in the family Pithophoraceae and a unique behavior of chloroplasts reported in closely related Aegagropila linnaei, the famous lake-ball alga, implies a possible role of lipid 1 or its acyl derivatives in ecol. adaptation to dysphotic niches. In the experiment, the researchers used many compounds, for example, (Chloromethanetriyl)tribenzene (cas: 76-83-5Name: (Chloromethanetriyl)tribenzene).

(Chloromethanetriyl)tribenzene (cas: 76-83-5) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Name: (Chloromethanetriyl)tribenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Aliphatic polyamide nanofilm with ordered nanostripe, synergistic pore size and charge density for the enhancement of cation sieving was written by Yuan, Bingbing;Zhao, Siheng;Xu, Shaojie;Wang, Ning;Hu, Ping;Chen, Kuo;Jiang, Juhui;Cui, Jiabao;Zhang, Xiaozhuan;You, Meng;Niu, Q. Jason. And the article was included in Journal of Membrane Science in 2022.Name: Trimesoylchloride This article mentions the following:

Enhanced cation sieving selectivity is significant for polyamide (PA) nanofiltration membrane in terms of extracting lithium from Salt Lake brines, which enable to reduce production cost and operating energy consumption. Herein, an aliphatic PA nanofilm with ordered nanostripe was fabricated using a novel distorted and non-coplanar monomer, cyclopentane tetracarboxylic acid chloride (CPTC). Because of the fine-tuning of the dendrimer porous layer, the resultant aliphatic PA membrane revealed decreased thickness in separation layer, and an enhanced synergistic effect of size exclusion and Donnan equilibrium on mono-/divalent cation. Separation experiments indicated that a higher MgCl2 rejection (up to 98.36%) and a lower LiCl rejection (33.3%) were obtained, thus achieving a good cation selectivity (48.25 for Na⁺/Mg2⁺, 36.5 for Li⁺/Mg2⁺). This result was better compared with the full-aromatic and most of the literature reported pos. charged PA membranes. Moreover, water flux of the CPTC-tris(2-aminoethyl) amine (TAEA) membrane with nanostripe structure (N-CPTC-TAEA) increased 3.98-4.74 times (for example, 135.9 ± 4.62 for 2000 ppm LiCl) that of the CPTC-TAEA membrane. Meanwhile, the N-CPTC-TAEA also exhibited a better antifouling property than that of the full-aromatic membrane. This study demonstrates that the N-CPTC-TAEA tends to be an alternative membrane material for cation separation In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Name: Trimesoylchloride).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: Trimesoylchloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Design and synthesis of novel pyrrolo[2,3-b]pyridine derivatives targeting ^V600EBRAF was written by Abdel-Maksoud, Mohammed S.;Ali, Eslam M. H.;Ammar, Usama M.;Mersal, Karim I.;Yoo, Kyung Ho;Oh, Chang-Hyun. And the article was included in Bioorganic & Medicinal Chemistry in 2020.Quality Control of 3-(Trifluoromethyl)benzene-1-sulfonyl chloride This article mentions the following:

Several pyrrolo[2,3-b]pyridine-based B-RAF inhibitors are well known and some of them are currently FDA approved as anticancer agents. Based on the structure of these FDA approved ^V600EB-RAF inhibitors, two series of pyrrolo[2,3-b]pyridine scaffold were designed and synthesized in attempt to develop new potent ^V600EB-RAF inhibitors. The 38 synthesized compounds were biol. evaluated for their ^V600EB-RAF inhibitory effect at single dose (10 μM). Compounds with high percent inhibition were tested to determine their IC₅₀ over ^V600EB-RAF. Compounds 34e and 35 showed the highest inhibitory effect with IC₅₀ values of 0.085 μM and 0.080 μM, resp. Headed for excessive biol. evaluation, the synthesized derivatives were tested over sixty diverse human cancer cell lines. Only compound 35(I) emerged as a potent cytotoxic agent against different panel of human cancer cell lines. In the experiment, the researchers used many compounds, for example, 3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6Quality Control of 3-(Trifluoromethyl)benzene-1-sulfonyl chloride).

3-(Trifluoromethyl)benzene-1-sulfonyl chloride (cas: 777-44-6) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Quality Control of 3-(Trifluoromethyl)benzene-1-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and urease inhibitory activities of benzophenone semicarbazones/thiosemicarbazones was written by Arshia, Arshia;Khan, Ajmal;Khan, Khalid Mohammed;Saad, Syed Muhammad;Siddiqui, Nida Iqbal;Javaid, Sumaira;Perveen, Shahnaz;Choudhary, M. Iqbal. And the article was included in Medicinal Chemistry Research in 2016.Name: 2,4-Dichlorophenylisothiocyanate This article mentions the following:

Twenty-five benzophenone semicarbazones and thiosemicarbazones were synthesized starting from benzophenones via hydrazones treated with different aryl isocyanates and isothiocyantes under reflux. All synthetic derivatives were evaluated for their urease inhibitory potential. A good-to-moderate inhibition trend against urease was observed with IC₅₀ values in the range of 8.7-119.5 μM, when compared with the standard thiourea (IC₅₀ = 21.2 ± 1.3 μM). One compound showed better inhibition than the standard having an IC₅₀ value of 8.7 ± 0.6 μM. Nine compounds with IC₅₀ values within the range of 26.1-43.6 μM, demonstrated good-to-moderate activities while one compound (IC₅₀ = 119.5 ± 1.6 μM) displayed very weak activity. The enzyme kinetic studies on the 2 most active compounds were performed to deduce their modes of inhibition and K_i values. In the experiment, the researchers used many compounds, for example, 2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1Name: 2,4-Dichlorophenylisothiocyanate).

2,4-Dichlorophenylisothiocyanate (cas: 6590-96-1) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: 2,4-Dichlorophenylisothiocyanate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Mechanism of radical chlorination of hydrocarbons with N-halosulfonamides. Effect of structural factors on the reaction selectivity was written by Dneprovskii, A. S.;Eliseenkov, E. V.;Osmonov, T. A.. And the article was included in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) in 1998.Recommanded Product: 14070-51-0 This article mentions the following:

Radical chlorination of alkanes and their derivatives with N-halosulfonamides was studied by the method of competing reactions under conditions where H is abstracted only by sulfonylaminyl radical. The selectivity of reactions with N-halosulfonamides is intermediate between radical chlorination and bromination with mol. halogens. Radicals with captodative properties exhibit the highest selectivity. In the experiment, the researchers used many compounds, for example, 2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0Recommanded Product: 14070-51-0).

2-Chlorobenzo[d]isothiazol-3(2H)-one 1,1-dioxide (cas: 14070-51-0) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 14070-51-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics