Tag: 200-300

Application of 10007-84-8On September 1, 2013 ,《A semi-empirical spectrophotometric (SESp) method for the indirect determination of the ratio of cationic micellar binding constants of counterions X- and Br- (KX/KBr)》 was published in Journal of Oleo Science. The article was written by Khan, Mohammad Niyaz; Yusof, Nor Saadah Mohd.; Abdul Razak, Norazizah. The article contains the following contents:

The semi-empirical spectrophotometric (SESp) method, for the indirect determination of ion exchange constants (KXBr) of ion exchange processes occurring between counterions (X- and Br-) at the cationic micellar surface, is described in this article. The method uses an anionic spectrophotometric probe mol., N-(2-methoxyphenyl)phthalamate ion (1-), which measures the effects of varying concentrations of inert inorganic or organic salt (NavX, v = 1, 2) on absorbance, (Aob) at 310 nm, of samples containing constant concentrations of 1-, NaOH and cationic micelles. The observed data fit satisfactorily to an empirical equation which gives the values of two empirical constants These empirical constants lead to the determination of KXBr (= KX/KBr with KX and KBr representing cationic micellar binding constants of counterions X and Br-). This method gives values of KXBr for both moderately hydrophobic and hydrophilic X-. The values of KXBr, obtained by using this method, are comparable with the corresponding values of KXBr, obtained by the use of semi-empirical kinetic (SEK) method, for different moderately hydrophobic X. The values of KXBr for X = Cl- and 2,6-Cl2C6H3CO2-, obtained by the use of SESp and SEK methods, are similar to those obtained by the use of other different conventional methods.Sodium 2,6-dichlorobenzoate(cas: 10007-84-8Application of 10007-84-8) was used in this study.

Sodium 2,6-dichlorobenzoate(cas: 10007-84-8) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Application of 10007-84-8 Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Cu-Catalyzed Photoredox Chlorosulfonation of Alkenes and Alkynes》 was written by Alkan-Zambada, Murat; Hu, Xile. Reference of 4-Chlorobenzenesulfonyl chlorideThis research focused onvisible light photoredox chlorosulfonation alkene alkyne copper photocatalyst. The article conveys some information:

Visible-light photoredox chlorosulfonation of alkenes and alkynes is achieved using a Cu photocatalyst. The reactions occur under mild conditions, have broad scope, and have high functional group tolerance. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Reference of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Reference of 4-Chlorobenzenesulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocksIn 2019 ,《Synthesis and structural features of N-[(2-(trimethylsilyl)oxy)phenyl]-arylsulfonamides》 was published in Journal of Molecular Structure. The article was written by Nikonov, Alexey Yu; Sterkhova, Irina V.; Serykh, Valeriy Yu; Kolyvanov, Nikita A.; Lazareva, Natalya F.. The article contains the following contents:

N-[(2-(Trimethylsilyl)oxy)phenyl]-4-methylbenzenesulfonamide and N-[(2-trimethylsilyloxy)phenyl]-4-chlorobenzenesulfonamide were prepared by two different methods. Their structures were studied by X-ray single-crystal anal. and DFT calculations including MO and NBO analyses. Self-association in solutions was shown by FTIR-spectroscopy. In the part of experimental materials, we found many familiar compounds, such as 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Category: chlorides-buliding-blocks)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Jin, Xin; Cao, Jianguo; Zhao, Qingjie; Wang, Qi; Guo, Hongmei; Aisa, Haji Akber; Huang, Guozheng published their research in Journal of the Serbian Chemical Society in 2021. The article was titled 《Synthesis of new derivatives of alepterolic acid via click chemistry》.Computed Properties of C7H6BrCl The article contains the following contents:

In this article, 23 new derivatives of alepterolic acid combined with 1,2,3-triazole I (R = Ph, 2-methylphenyl, 4-fluorophenyl, etc.) were designed and synthesized by esterification and click chem. reaction in a fast, conventional and efficient way. All the products were obtained in good yields (72 to 97%). The use of the easily available reactants and the common reaction conditions furnish an efficient method for the synthesis of alepterolic acid derivatives I. The preparation of these compounds would enable further biol. evaluation in the future. In the experimental materials used by the author, we found 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Computed Properties of C7H6BrCl)

1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.Computed Properties of C7H6BrCl It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Clustering-Triggered Ultralong Room-Temperature Phosphorescence of Organic Crystals through Halogen-Mediated Molecular Assembly》 was published in Journal of Physical Chemistry Letters in 2020. These research results belong to Sun, Huili; Ding, Riqing; Lv, Shanling; Zhou, Shasha; Guo, Sidan; Qian, Zhaosheng; Feng, Hui. Recommanded Product: 622-95-7 The article mentions the following:

To achieve efficient room-temperature phosphorescence of organic materials with ultralong lifetime, it is imperative to resolve the dilemma that the introduction of heavy atoms simultaneously improves emission efficiencies and shortens the emission lifetimes. Herein, we report a new mol. design approach for halogenated luminogens with a methylene bridge to avoid the lifetime shortening induced by heavy halogens and propose a general mol. engineering strategy to realize efficient and ultralong room-temperature phosphorescence via halogen-mediated mol. clustering. The halogenated N-benzylcarbazole derivatives show distinct photophys. behaviors depending on different phys. states, including single-mol. state and cluster state. Their crystals demonstrate the halogen-dependent emission duration of room-temperature phosphorescence upon excitation. Exptl. data and theor. anal. indicate that halogen-regulated mol. clustering in the crystal is responsible for the generation of efficient ultralong room-temperature phosphorescence, and halogen-dominated mol. engineering favors the promotion of the intersystem crossing process and the following triplet emissions.1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Recommanded Product: 622-95-7) was used in this study.

1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) may be used to synthesize 1-(4-chlorobenzyl)-2-(pyrrolidin-1-yl-methyl)-1H-benzimidazole dihydrochloride.Recommanded Product: 622-95-7 It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Design, synthesis and antibacterial activity evaluation of novel 2-(4-((1-aryl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)2-(2-oxoazetidin-1-yl)acetamide derivatives》 was published in Journal of Heterocyclic Chemistry in 2020. These research results belong to Zarei, Samaneh; Komeili, Golzar; Bahadorikhalili, Saeed; Yahya-Meymandi, Azadeh; Karami-Zarandi, Morteza; Larijani, Bagher; Biglar, Mahmood; Sadat Ebrahimi, Seyed Esmaeil; Mahdavi, Mohammad. Reference of 1-(Bromomethyl)-4-chlorobenzene The article mentions the following:

In this paper, a novel series of 2-(4-((1-aryl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)2-(2-oxoazetidin-1-yl)acetamide derivatives I (R = t-Bu, Cy; R1 = 4-F, 2-Me, 4-NO2, etc.; R2 = H, OMe) are synthesized in two steps. The first step involved Ugi multicomponent reaction of β-alanine, o-(propargyl)benzaldehydes 3-R2-4-(HCCCH2O)C6H3CHO and isocyanide derivatives RN+C-. The product of this step, underwent a click 1,3-dipolar cycloaddition reaction with benzyl azide derivatives R1C6H4CH2N3. The 2-(4-((1-aryl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)2-(2-oxoazetidin-1-yl)acetamide products I were characterized and their antibacterial activities were evaluated against various G-pos. (Staphylococcus aureus and Bacillus subtilis) and G-neg. (Pseudomonas aeruginosa and Escherichia coli) bacteria, using minimal inhibition concentration The compounds I showed very good antimicrobial activity and a number of products have been more active than ciprofloxacin. In addition to this study using 1-(Bromomethyl)-4-chlorobenzene, there are many other studies that have used 1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7Reference of 1-(Bromomethyl)-4-chlorobenzene) was used in this study.

1-(Bromomethyl)-4-chlorobenzene(cas: 622-95-7) is a useful reagent for the preparation of panicinotam derivatives for use as anti-inflammatory agents or immunomodulators.Reference of 1-(Bromomethyl)-4-chlorobenzene It can be synthesized by reacting 4-chlorobenzyl alcohol with bromodimethylsulfonium bromide (BDMS) It can also be synthesized by refluxing a mixture of 4-chlorobenzaldehyde, chlorotrimethylsilane, 1,1,3,3-tetramethyldisiloxane and lithium bromide.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《The natural production of organohalogens by basidiomycetes》 were Verhagen, Frank J. M.; Field, J. A.; Swarts, H. J.; Wijnberg, J. B. P. A.. And the article was published in Organohalogen Compounds in 1996. Computed Properties of C8H6Cl2O3 The author mentioned the following in the article:

The ubiquity of organohalogen production among basidiomycetes was investigated in 191 fungal strains by monitoring the production of adsorbable organic halogen (AOX) and by determination of chlorinated anisyl metabolites (CAM). For a AOX screening the strains were grown in a liquid medium and AOX was determined in the culture fluid. Almost 25% of the strains tested had a low AOX production (0.1-5.0 mg AOX/L), 16% a moderate production (0.5-5.0 mg AOX/L), and 9% a high production (5-67 mg AOX/L). The highest producers were species of the genera Hypholoma, Mycena, and Bjerkandera with AOX productions of 1074-30,893 mg AOX per kg dry weight of mycelia biomass. These species produced also AOX when cultivated on natural lignocellulosic substrates. CAM were detected in the extracellular fluid of the mycelium of 7 different basidiomycetes; in the genera Mycena, Peniophora, Phellinus, and Phylloporia CAM production was observed for the first time. Organohalogen production was a ubiquitous capacity among commonly occurring basidiomycetes fungi and they might be a major source of natural organohalogens in forest ecosystems. After reading the article, we found that the author used 3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7Computed Properties of C8H6Cl2O3)

3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Computed Properties of C8H6Cl2O3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 37908-97-7On March 7, 2008, Vaswani, Rishi G.; Chamberlin, A. Richard published an article in Journal of Organic Chemistry. The article was 《Stereocontrolled Total Synthesis of (-)-Kaitocephalin》. The article mentions the following:

This paper describes the successful implementation of a stereocontrolled strategy for the total chem. synthesis of the pyrrolidine-based alkaloid (-)-kaitocephalin (I). This scalable synthetic route profits from the strategic utilization of substrate-controlled manipulations for the iterative installation of the requisite stereogenic centers. The key transformations include a diastereoselective modified Claisen condensation, a chemo- and diastereoselective reduction of a β-keto ester, and the substrate-directed hydrogenation of a dehydroamino ester derivative During the course of our investigations, an interesting stereoconvergent cyclization reaction was discovered for the efficient assembly of the kaitocephalin 2,2,5-trisubstituted pyrrolidine core. The experimental part of the paper was very detailed, including the reaction process of 3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7Related Products of 37908-97-7)

3,5-Dichloro-4-methoxybenzoic acid(cas: 37908-97-7) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Related Products of 37908-97-7 Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Firmness of union of organic radicals and reaction velocity. II. The saponification of esters, addition of hydrogen sulfide to nitroes and the transformation of alkyl chlorides into ethers》 was published in Justus Liebigs Annalen der Chemie in 1927. These research results belong to Kindler, Karl. Electric Literature of C11H13ClO2 The article mentions the following:

cf. C. A. 21, 77. In the saponification of aromatic esters with H2SO4, the following values of k were obtained: m-MeOC6H4CO2Et, 0.0587; 3,4-CH2O2:C6H3CO2Et, 0.0203; Et p-methylmercaptobenzoate, b15 168°, m. 28°, k 0.0388; Et p-ethylbenzoate, b15, 129-30°, 0.0222; p-PhC6H4CO2Et, 0.0536. From these the firmness of union is calculated as follows: Ph, 100; m-MeOC6H4, 83.5; p-PhC6H4, 91.4; p-MeSC6H4, 126; p-EtC6H4, 221; 3,4-CH2O2:C5H3, 241. AcOEt and H2SO4 give a value for k of 0.481; EtCO2Et, 0.226; PrCO2Et, 0.132; BuCO2Et, 0.126; AmCo2Et, 0.131; heptylic acid and caprylic acid also gave values of 0.130; PhCH2CO2Et, 0.636; p-MeOC6H4CH2CO2Et, 0.68O; p-MeC6H4CH2CO2Et, 0-585; p-H2NC6H4CO2Et, 0.325; p-ClC6H4CH2CO2Et, 1.62; p-O2NC6H4CH2CO2Et, 4.57; PhCH2CH2CO2Et, 0.343; p-MeOC6H4CH2CH2CO2Et, b14 165° 0.288; 3,4-CH2O2.C6H3CH2CH2CO2Et, 0.329; p-ClC6H4CH2CO2Et, 0.516; PhCH2CH2CH2CO2Et 0.199; PhCH:CHCO2Et, 0.106; o-MeOC6H4CH:CHCO2Et, 0.0399; p-MeOC6H4CH:CHCO2Et, 0.0444; 3,4-CH2O2:C6H4CH:CHCO2Et, 0.0614; p-MeC6H4CH:CHCO2Et, 0.0754; o-ClC6H4CH:CHCO2Et, 0.211; p-ClC6H4CH:CHCO2Et, 0.215; o-O2NC6H4CH:CHCO2Et, 0.841; m-O2NC6H4CH:CHCO2Et, 0.798; p-O2NC6H4CH:CHCO2Et, 1.037. From these values the relative firmness of union to the group CO2Et is calculated for each of tile above alkyl and aryl groups. The following values of k were obtained for the reaction of nitriles with H2S, the time in min. being given first: PhCH2CN, 345, 0.001105; Ph(CH2)2CN, 240, 0.000499; Ph(CH2)3CN 345, 0.000414; p-ClC6H4CH2CN, 285, 0.002921; EtCN, 1440, O.000158; PrCN, 1440, 0.000094. γ-Phenylthiobutyramide, pale yellow, m. 62° (corrected); p-chlorophenylthioacetamde, egg yolk-yellow, m. 128-9° (corrected); thiobutyramide, red-brown oil. The reaction of alkyl chlorides with EtONa at 31.6° gave the following values for k: PhCH3Cl, 8.70; p-ClC6H4CH2Cl. 15.9; PhCH2-CH2Cl, 0.69; Ph(CH2)3Cl, 0.099. From these values the firmness of union toward Cl is calculated: p-ClC6H4CH2, 54.7; PhCH2, 100; Ph(CH2)2, 1261; Ph(CH2)3, 8778. In the experimental materials used by the author, we found Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Electric Literature of C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Electric Literature of C11H13ClO2 Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Name: 4-Chlorobenzenesulfonyl chlorideIn 2022 ,《Time and Atom Economical Regio- and Chemoselective Radical Cyclization of Unactivated 1,6-Enynes Under Metal- and Oxidant-Free Conditions》 appeared in Chemistry – A European Journal. The author of the article were Mutra, Mohana Reddy; Li, Jing; Chen, Yu-Ting; Wang, Jeh-Jeng. The article conveys some information:

Authors developed time-atom economic regio- and chemoselective sulfonyl radical triggered 5-exo-dig cyclization of unactivated 1,6-enynes with sulfonyl halides under metal, additive-free reaction conditions to achieve highly substituted five-membered heterocyclic compounds I (R1 = Me, Ph, 3-O2NC6H4, etc.; R2 = Me, Ph; R3 = H, Me, t-Bu, etc.; X = N(Ts), O, NC(O)Ph, etc.). This transformation creates three new bonds, such as C-SO2, C-C, and active C-I/Br bonds. Importantly, one-pot protocols produce desired products directly from sodium sulfinates and have an addnl. advantage such as minimising chem. waste, saving time, and simplifying practical aspects compared to existing protocols. After reading the article, we found that the author used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Name: 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Name: 4-Chlorobenzenesulfonyl chloride Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics