Tag: 200-300

On March 15, 2018, Karthick, S.; Thirupugalmani, K.; Shanmugam, G.; Kannan, V.; Brahadeeswaran, S. published an article.Recommanded Product: 2-Chloro-4-nitrobenzoic acid The title of the article was Experimental and quantum chemical studies on N-H—O hydrogen bonded helical chain type Morpholinium 2-chloro-4-nitrobenzoate: A phasematchable organic nonlinear optical material. And the article contained the following:

We report on the studies performed on Morpholinium 2-chloro-4-nitrobenzoate (M2C4N), a second order nonlinear optical (NLO) material, which has been proved to crystallize with chiral structure as compared to its other two variants. The synthesized powder was studied for its composition, crystalline phase and NLO efficiency and phase matchability. The solubility and the metastable zone width (MSZW) of the title compound were measured for the growth of bulk crystals of M2C4N. A smoky pattern observed in the middle region of the crystals that could prevent it from optical applications was greatly reduced, through suitable modifications in the growth process. The optical properties such as luminescence and laser damage threshold resistance were studied for the bulk crystals whereas the mol. vibrations of M2C4N were studied through Fourier transform IR (FTIR) and FT-Raman spectral anal. using the polycrystalline powders derived from the single crystals. In addition, quantum chem. studies on M2C4N mol. were performed by using d. functional theory (DFT) at the B3LYP/6-311++G (d, p) basis set. These studies showed that the M2C4N is a phase matchable NLO crystal and could be used for device fabrication. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Recommanded Product: 2-Chloro-4-nitrobenzoic acid

The Article related to exptl quantum chem nitrogen hydrogen oxygen bonded helical chain, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Recommanded Product: 2-Chloro-4-nitrobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ayad, Suliman; Posey, Victoria; Das, Anjan; Montgomery, Jason M.; Hanson, Kenneth published an article in 2019, the title of the article was Enantioenrichment of racemic BINOL by way of excited state proton transfer.Recommanded Product: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate And the article contains the following content:

Here the authors report a method for enantioenriching BINOL using a chiral auxiliary and an excited state proton transfer (ESPT) event. Regardless of the starting enantiomeric excess (ee), after irradiation the solution reaches a photostationary state whose ee is dependent solely on the identity of the chiral auxiliary group. The enantioenriched BINOL is easily recovered by cleaving the auxiliary group in mild conditions. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Recommanded Product: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

The Article related to enantioenrichment racemic binol excited state proton transfer, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Recommanded Product: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On July 16, 2021, Qu, Zhonghua; Chen, Xing; Zhong, Shuai; Deng, Guo-Jun; Huang, Huawen published an article.HPLC of Formula: 99-60-5 The title of the article was NaI/PPh3-Mediated Photochemical Reduction and Amination of Nitroarenes. And the article contained the following:

A mild transition-metal- and photosensitizer-free photoredox system based on the combination of NaI and PPh3 was found to enable highly selective reduction of nitroarenes. This protocol tolerated a broad range of reducible functional groups such as halogen (Cl, Br and even I), aldehyde, ketone, carboxyl and cyano. Moreover, the photoredox catalysis with NaI and stoichiometric PPh3 provides also an alternative entry to Cadogan-type reductive amination when o-nitrobiarenes were used. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).HPLC of Formula: 99-60-5

The Article related to chemoselective nitroarene reduction amination photochem, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.HPLC of Formula: 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 21, 2022, Bhalodi, Esha H.; Patel, Krupa N.; Bedekar, Ashutosh V. published an article.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate The title of the article was Synthesis and resolution of 2-amino-5-aza[6]helicene. And the article contained the following:

The synthesis of 2-amino-5-aza[6]helicene and its derivatives is reported. The diastereomeric (R)-menthylcarbamate derivative of this aza[6]helicene is prepared and its isomers were phys. separated by column chromatog. and their optical properties were measured. Optically pure isomer (P)-2-amino-5-aza[6]helicene was generated and its Boc-derivative was prepared The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

The Article related to azahelicene preparation chiral resolution, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.Safety of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 16, 2018, Yasukouchi, Hiroaki; Nishiyama, Akira; Mitsuda, Masaru published an article.Computed Properties of 14602-86-9 The title of the article was Safe and Efficient Phosgenation Reactions in a Continuous Flow Reactor. And the article contained the following:

Phosgene is widely used in organic synthesis owing to its high reactivity, utility, and cost efficiency. However, the use of phosgene in batch processes on the industrial scale is challenging owing to its toxicity. An effective method to minimize reaction volumes and mitigate the safety risks associated with hazardous chems. is the use of flow reactors. Consequently, we have established a flow reaction system using triphosgene and tributylamine, which affords a homogeneous reaction that avoids clogging issues. In addition, we have demonstrated that this methodol. can be applied to a wide variety of phosgene reactions, including the preparation of pharmaceutical intermediates, in good to excellent yields. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Computed Properties of 14602-86-9

The Article related to phosgenation reactor, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Computed Properties of 14602-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 29, 2020, Karthick, S.; Thirupugalmani, K.; Krishnakumar, M.; Kannan, V.; Vinitha, G.; Brahadeeswaran, S. published an article.Formula: C7H4ClNO4 The title of the article was Synthesis, structural, dielectric, laser damage threshold, third order nonlinear optical and quantum chemical investigations on a novel organic crystalline material: Pyrrolidin-1-ium 2-chloro-4-nitrobenzoate 2-chloro-4-nitrobenzoic acid for opto-electronic applications. And the article contained the following:

It is reported that a novel third order organic nonlinear optical material namely, Pyrrolidin-1-ium 2-chloro-4-nitrobenzoate 2-chloro-4-nitrobenzoic acid (PCNCN) has been synthesized and grown by isothermal solvent evaporation solution growth technique. Single crystal X-ray diffraction anal. revealed that PCNCN belonged to monoclinic crystal system with a centrosym. space group of P21/c. The morphol. of the as grown PCNCN crystal compared well with that obtained by theor. generated morphol. The mol. vibrations of PCNCN were analyzed through Fourier transform IR and NMR spectrum analyses. Optical properties such as transmittance, photoluminescence, and laser damage threshold were studied. The thermal stability of PCNCN was measured through TG-DTA measurement. The dielec. properties such as dielec. constant, dielec. loss, ac conductivity and activation energy of PCNCN single crystal were studied as a function of frequency at different temperatures The PCNCN single crystals were further characterized for their third order nonlinear optical properties such as nonlinear absorption coefficient, nonlinear refractive index and optical limiting behavior using continuous wave Nd: YAG laser. The quantum chem. investigations were performed using B3LYP/6-311++G(d, p) basis set. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Formula: C7H4ClNO4

The Article related to dielec constant laser damage threshold organic crystalline material, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Optical Properties (Linear) and other aspects.Formula: C7H4ClNO4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Jianxia; Namila, E.; Bai, Chaolumen; Baiyin, Menghe; Bao, Agula; Bao, Yong-Sheng published an article in 2018, the title of the article was Transesterification of (hetero)aryl esters with phenols by an Earth-abundant metal catalyst.COA of Formula: C7H4ClNO4 And the article contains the following content:

Readily available and inexpensive Earth-abundant alkali metal species were used as efficient catalysts for the transesterification of aryl or heteroaryl esters with phenols which is a challenging and underdeveloped transformation. The simple conditions and the use of heterogeneous alkali metal catalyst make this protocol very environmentally friendly and practical. This reaction fills in the missing part in transesterification reaction of phenols and provides an efficient approach to aryl esters, which are widely used in the synthetic and pharmaceutical industry. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).COA of Formula: C7H4ClNO4

The Article related to aryl ester preparation green chem, ester preparation phenol alkali metal catalyst transesterification, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.COA of Formula: C7H4ClNO4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Hlazunova, T. V.; Panasenko, O. I.; Knysh, Ye. H. published an article in 2020, the title of the article was The synthesis of 3-methyl-6-R-[1,2,4]triazolo[3,4-b]- [1,3,4]thiadiazole derivatives.Formula: C7H4ClNO4 And the article contains the following content:

Synthesis and structure conformation of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as potential biol. active compds was discussed. It was shown that the heterocyclization reaction of 4-amino-5-methyl-4H- 1,2,4-triazole-3-thiol with carboxylic acids in the excess of phosphorus oxychloride yields 3-methyl-6-R-[1,2,4]- triazolo[3,4-b][1,3,4]thiadiazoles. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Formula: C7H4ClNO4

The Article related to amino methyl triazole thiol carboxylic acid heterocyclization, methyl aryl triazolo thiadiazole preparation, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Formula: C7H4ClNO4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 15, 2011, Rogers, Steven A.; Lindsey, Erick A.; Whitehead, Daniel C.; Mullikin, Trey; Melander, Christian published an article.Category: chlorides-buliding-blocks The title of the article was Synthesis and biological evaluation of 2-aminoimidazole/carbamate hybrid anti-biofilm and anti-microbial agents. And the article contained the following:

The successful marriage of structural features from the 2-aminoimidazole and menthyl carbamate classes of anti-biofilm agents has resulted in the development of a novel hybrid scaffold of biofilm modulators. The compounds were evaluated against a panel of four bacterial strains for anti-biofilm and anti-microbial activity. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Category: chlorides-buliding-blocks

The Article related to menthyl imidazolylalkyltriazolylalkylcarbamate preparation antimicrobial biofilm inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ramzan, Ayesha; Nazeer, Areesha; Irfan, Ahmad; Al-Sehemi, Abdullah G.; Verpoort, Francis; Khatak, Zafar A.; Ahmad, Aftab; Munawar, Munawar A.; Khan, Misbahul A.; Basra, Muhammad Asim Raza published an article in 2019, the title of the article was Synthesis and Antiplatelet Potential Evaluation of 1,3,4-Oxadiazoles Derivatives.Synthetic Route of 99-60-5 And the article contains the following content:

A novel series of 2-(3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)-5-aryl-1,3,4-oxadiazoles I [R = furan-2-yl, pyridin-4-yl, 4-tolyl, etc.] were synthesized from corresponding hydrazones and evaluated their antiplatelet aggregation effect induced by arachidonic acid and collagen. Spectral data and elemental evaluation were used to confirm the structure of the compounds while mol. docking against cyclooxygenase 1 and 2 (COX1 & COX2) and quant. structure-activity relationship (QSAR) were performed in describing their antiplatelet potential. All synthesized compounds I exhibited more than 50% platelet aggregation inhibition against both arachidonic acid and collagen. Antiplatelet activities results showed that I [R = 4-nitrophenyl, furan-2-yl] compounds was highest % inhibition against arachidonic acid. High Egap and ionization potential values showed that the compound I [R = 4-bromophenyl, 4-tolyl, furan-2-yl] were supposed to be more active and good electron donor while I [R = 4-nitrophenyl, 4-fluorophenyl, 4-bromophenyl, 4-tolyl, pyridin-4-yl, 2-chloro-4-nitrophenyl] might be more active due to more electrophilic sites. Interaction with more than one residues in the binding pocket of COX-1 in comparison with aspirin and ligand efficacy (LE) consequences showed that compounds were excellent action potential for COX-1. Computational evaluations were in good agreement with antiplatelet activities of the compounds All compounds might be promising antiplatelet agents especially I [R = 4-nitrophenyl, furan-2-yl] and helpful in the synthesis of new drugs for the treatment of cardiovascular diseases (CVDs). The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Synthetic Route of 99-60-5

The Article related to diphenyl pyrazolopyridinyl aryloxadiazole preparation antiplatelet activity mol docking, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics