Tag: 200-300

Prech, Jan; Matousek, Vacla; Vaclavik, Jiri; Pechacek, Jan; Syslova, Kamila; Sot, Petr; Januscak, Jakub; Vilhanova, Beata; Kuzma, Marek; Toman, Jaromir; Kacer, Petr published an article in 2013, the title of the article was Determination of enantiomeric composition of substituted tetrahydroisoquinolines based on derivatization with menthyl chloroformate.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate And the article contains the following content:

A method for the anal. of the optical purity of a series of chiral substituted tetrahydroisoquinolines (THIQs) was developed. The method is based on pre-column derivatization of the analytes with the derivatization reagent (-)-(1R)-menthyl chloroformate. The derivatization reaction selectively gives diastereomeric carbamates that are resolvable on an achiral non-polar GC column. The developed technique covers variously substituted THIQs, which differ significantly in volatility, steric and electronic properties. In all cases, the resolution factors (R) exceeded the value of 1.5. The method represents a robust way of anal. of mixtures of THIQs, which are often present in various matrixes such as body fluids, tissues and reaction mixtures The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

The Article related to enantiomer tetrahydroisoquinoline menthyl chloroformate derivatization gc ei ms, Biochemical Methods: Other (Not Covered At Other Subsections) and other aspects.Quality Control of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 5, 2021, Yokoyama, Akihiro; Ishii, Arisa; Ohishi, Tomoyuki; Kikkawa, Shoko; Azumaya, Isao published an article.Synthetic Route of 99-60-5 The title of the article was Synthesis of a coronene analogue containing an amide bond by Pd-mediated intramolecular C-C bond formation of 2-halogenated 4-(alkylamino)benzoic acid cyclic trimer. And the article contained the following:

A coronene analog containing amide linkage was synthesized from a halogenated cyclic triamide by palladium-mediated intramol. C-C bond formation (I → II). The cyclic triamide was formed from the condensation of 2-chloro-4-(isobutylamino)benzoic acid in the presence of dichlorotriphenylphosphorane in 1,1,2,2-tetrachloroethane. By contrast, the condensation of 2-bromo counterpart required silicon tetrachloride in pyridine. The intramol. C-C bond formation, which yielded the target coronene analog, occurred during the reaction of bromo-substituted cyclic triamide with palladium(II) acetate, triphenylphosphine, and potassium carbonate in N,N-dimethylformamide. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Synthetic Route of 99-60-5

The Article related to coronene amide synthesis palladium mediated intramol cyclization, Heterocyclic Compounds (More Than One Hetero Atom): Eight- and Higher-Membered Rings and other aspects.Synthetic Route of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Vrbicky, Martin; Macek, Karel; Pochobradsky, Jaroslav; Svoboda, Jan; Sedlak, Milos; Drabina, Pavel published an article in 2022, the title of the article was The asymmetric Henry reaction as synthetic tool for the preparation of the drugs linezolid and rivaroxaban.Recommanded Product: 14602-86-9 And the article contains the following content:

The human drugs – the antibiotic linezolid and the anticoagulant rivaroxaban – belong among modern pharmaceutics, which contain an oxazolidine-2-one moiety bearing a stereogenic center. The chirality of these drugs is a fundamental attribute for their biol. activity. Herein, one of the efficient asym. syntheses of these drugs was studied in detail. Highly enantioselective catalysts were tested in the key step of the synthetic procedure, i.e., the asym. Henry reaction, under different reaction conditions, using several starting aldehydes. The corresponding nitroaldols as chiral intermediates in the syntheses of these drugs were obtained in high yields and enantiomeric excesses of up to 91% ee. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Recommanded Product: 14602-86-9

The Article related to linezolid rivaroxaban preparation enantioselective, asymmetric henry reaction, enantioselective catalysis, linezolid, oxazolidine-2-one derivatives, rivaroxaban, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.Recommanded Product: 14602-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 31, 2020, Zhou, Shiyang; Huang, Gangliang published an article.Related Products of 99-60-5 The title of the article was Design, synthesis and biological evaluation of novel 7H-benzo[c][1,3]dioxolo[4,5-f]chromen-7-one derivatives with potential anti-tumor activity. And the article contained the following:

In this study, a series of novel 7H-benzo[c][1,3]dioxolo[4,5-f]chromen-7-one derivatives I (R1 = H, NH2, NO2; R2 = H, Me, Et, i-Pr, COMe) were obtained by structural modification of the lead compounds with Fissitungfine B. A total 15 compounds were designed, synthesized and evaluated as tumor inhibitors. These target compounds have the novel chem. structures that named three six-membered rings including one lactone six-membered ring. In vitro assay, the results showed that the target compounds have a broad spectrum and strong anti-tumor activity. The inhibitory activity of the compound I (R1 = NO2; R2 = i-Pr) to MCF-7 was IC50 = 0.35 +/- 0.01μM, to A-549 was IC50 = 0.37 +/- 0.01μM, to Hela was IC50 = 0.56 +/- 0.02μM, to MDC-803 was IC50 = 0.53 +/- 0.02μM and COLO-205 was IC50 = 0.50 +/- 0.02μM in vitro. At the same time, in vivo anti-tumor activity assay results showed that the target compounds had a good inhibitory effect on tumor growth. Among them, the target compound I (R1 = NO2; R2 = i-Pr) had the best anti-tumor activity, it could inhibit tumor growth well at a low dose. The target compound I (R1 = NO2; R2 = i-Pr) could be used as a candidate drug for further research and development, in order to be used as early as application in the clin. treatment of tumors. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Related Products of 99-60-5

The Article related to benzodioxolochromenone preparation antitumor human, anti-tumor activity, design, fissitungfine b, synthesis, Heterocyclic Compounds (More Than One Hetero Atom): Dioxoles, Oxathioles, Dithioles and other aspects.Related Products of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 15, 2021, Giofre, Sabrina; Keller, Manfred; Lo Presti, Leonardo; Beccalli, Egle M.; Molteni, Letizia published an article.Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate The title of the article was Switchable Oxidative Reactions of N-allyl-2-Aminophenols: Palladium-Catalyzed Alkoxyacyloxylation vs an Intramolecular Diels-Alder Reaction. And the article contained the following:

The Pd(II)-catalyzed reaction of N-allyl-2-aminophenols in the presence of PhI(OCOR)2 as the oxidant resulted in an alkoxyacyloxylation process, with the formation of functionalized dihydro-1,4-benzoxazines. The reaction performed in the absence of palladium catalyst switched to an intramol. Diels-Alder reaction (IMDA) pathway, which was the result of an oxidative dearomatization of the 2-aminophenol, nucleophilic addition, and Diels-Alder reaction cascade, highlighting the role of the oxidant as both a nucleophilic donor and an oxidizing agent. The experimental process involved the reaction of (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate(cas: 14602-86-9).Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

The Article related to dihydrobenzoxazine tricyclic methanoindole preparation, allyl tosyl aminophenol tandem, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.Name: (1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl carbonochloridate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 1, 2021, Guzauskas, Matas; Narbutaitis, Edgaras; Volyniuk, Dmytro; Baryshnikov, Glib V.; Minaev, Boris F.; Agren, Hans; Chao, Yu-Chiang; Chang, Chia-Chih; Rutkis, Martins; Grazulevicius, Juozas V. published an article.Computed Properties of 80-07-9 The title of the article was Polymorph acceptor-based triads with photoinduced TADF for UV sensing. And the article contained the following:

In contrast to many donor-acceptor type organic luminophores exhibiting thermally activated delayed fluorescence (TADF), two deep blue TADF emitters designed in this work contain only typical electron accepting moieties with different electron accepting abilities. Derivatives of benzophenone and diphenylsulfone substituted with phenothiazine-5,5-dioxide donor moieties were synthesized and studied. In addition to the TADF, green to blue emission color switching and strong fluorescence intensity enhancement by more than 60 times was detected for THF solution of the derivative of phenothiazine-5,5-dioxide and benzophenone under increase of UV excitation dose. We proved by a variety of exptl. and theor. studies that the unusual photophys. properties of the derivative of benzophenone are mainly related to the formation of different conformers. The photostimulated intensity enhancement of the compound is due to the rise of the quantity of triplet states and their further crossing to singlet states. To our knowledge, this is the first observation of a combination of photoinduced color switching and triplet-dependent emission intensity enhancement. These properties are shown to be useful for UV sensing with very low detection limits (less than 10μW/cm2 for the toluene solution). Under gradual increase of UV excitation dose, the DMF solution demonstrated a green → blue color switchhing from (0.34; 0.44) to (0.17; 0.18) of CIE coordinates that can be detected by naked eye. The experimental process involved the reaction of 4,4′-Sulfonylbis(chlorobenzene)(cas: 80-07-9).Computed Properties of 80-07-9

The Article related to polymorph acceptor based triads photoinduced tadf uv sensing, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Luminescence and other aspects.Computed Properties of 80-07-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Scamporrino, Andrea A.; Puglisi, Concetto; Spina, Angela; Montaudo, Maurizio; Zampino, Daniela C.; Cicala, Gianluca; Ognibene, Giulia; Di Mauro, Chiara; Dattilo, Sandro; Mirabella, Emanuele F.; Recca, Giuseppe; Samperi, Filippo published an article in 2020, the title of the article was Synthesis and characterization of copoly(ether sulfone)s with different percentages of diphenolic acid units.Safety of 4,4′-Sulfonylbis(chlorobenzene) And the article contains the following content:

New functionalized poly(ether sulfone)s having different molar ratio (10, 20, 30, 50, 70, 100 mol%) of 4,4-bis phenoxy pentanoic acid unit (diphenolic acid; DPA) units were synthesized and characterized by (1H and 13C)-NMR, MALDI-TOF MS, FT-IR, DSC and DMA analyses. The microstructural anal. of the copolymers, obtained by 13C-NMR using an appropriate statistical model, shows a random distribution of copolymer sequences, as expected. The presence of different amount of DPA units along the polymer chains affects the chem. and phys. properties of the copolymers. The Tg and the contact angle values decrease as the molar fraction of DPA units increases, whereas the hydrophilicity increases. NMR and MALDI-TOF MS analyses show that all polymer chains are almost terminated with hydroxyl and chlorine as end groups. The presence of cyclic oligomers was also observed by MALDI-TOF MS anal. The experimental process involved the reaction of 4,4′-Sulfonylbis(chlorobenzene)(cas: 80-07-9).Safety of 4,4′-Sulfonylbis(chlorobenzene)

The Article related to polyethersulfone preparation thermal property heavy metal removal, dma, nmr, diphenolic acid, poly (ether sulfone)s, polyelectrolytes, random copolymers, synthesis, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Safety of 4,4′-Sulfonylbis(chlorobenzene)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kurdanova, Zhanna; Zhansitov, Azamat; Shakhmurzova, Kamila; Slonov, Azamat; Baykaziev, Artur; Khashirova, Svetlana published an article in 2021, the title of the article was Synthesis and Properties of Copolyphenylene Sulphones with Cardo Fragments.SDS of cas: 80-07-9 And the article contains the following content:

Copolymers based on 4,4′-dihydroxydiphenyl, phenolphthalein and 4,4′-dichlorodiphenyl sulfone were synthesized by the method of high temperature polycondensation. The structure of the synthesized copolymers was confirmed by IR spectroscopy. Their phys., mech. and thermal properties were investigated. It is shown that increases in the content of carded fragments lead to higher glass transition temperatures and heat resistance of the copolymers, as well as higher elastic and strength properties. The experimental process involved the reaction of 4,4′-Sulfonylbis(chlorobenzene)(cas: 80-07-9).SDS of cas: 80-07-9

The Article related to copolyphenylene sulfone cardo fragment synthesis property, ir spectroscopy, cardo fragments, heat resistance, polyphenylene sulfone, thermostability, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.SDS of cas: 80-07-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 20, 2020, Zhang, Gang; Li, Dongsheng; Yan, Guangming; Wang, Han; Zhang, Yu; Wu, Zhefu; Liu, Suilin; Wang, Xiaojun; Yang, Jie published an article.Related Products of 80-07-9 The title of the article was Design and Fabrication of a Low Dielectric Constant Poly(arylene ether sulfone) Film-Containing Cyclohexane Group. And the article contained the following:

In this study, a novel bisphenol-containing cyclohexane group [4,4′-(cyclohexane-1,1-diyl)bis(2-methoxyphenol) (CDBMP)] was synthesized. It was reacted with 4,4′-dichlorodiphenylsulfone to synthesize polyether sulfone-containing -OCH3 groups (PES-OCH3). Then, PES-OCH3 was reacted with BBr3 and (t-Boc)2O to yield PES-OH and PES-Boc, resp. The glass transition temperatures of PES-OCH3 and PES-OH were found to be 177.6 and 240.7°C, resp. The resultant resins exhibited good tensile strength and solubility (dissolved in N-Methyl-2-Pyrrolidine, DMF, and so on). Interestingly, PES-Boc showed excellent foam property, and the d. of the foam decreased from 1.23 to 0.012 g/cm3. Also, we found that the dielec. constant and dielec. loss values (107 Hz) of the foaming sample were in the range of 1.9-2.7 and 4.22 x 10-3 to 7.99 x 10-3, resp. The introduction of hydroxyl-Boc-assisted modification provides a controllable process to fabricate porous and ultra-light materials, and it can be potentially applied in these fields such as microelectronics and high speed communication systems. The experimental process involved the reaction of 4,4′-Sulfonylbis(chlorobenzene)(cas: 80-07-9).Related Products of 80-07-9

The Article related to dielec aromatic polyether polysulfone cyclohexane tensile thermal, ultralight porous polyether polysulfone dielec, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Related Products of 80-07-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 30, 2020, Liu, Limin; Li, Jianying; Yan, Tao; Cai, Mingzhong published an article.Electric Literature of 80-07-9 The title of the article was Novel preparation of poly(arylene ether sulfone amide)s via supported palladium-catalyzed carbonylative polymerization. And the article contained the following:

Two new aromatic diiodides with ether-sulfone linkages were synthesized via a 1-step procedure. Poly(arylene ether sulfone amide)s were synthesized by a supported Pd-catalyzed polycondensation of aromatic diiodides having ether-sulfone linkages, aromatic diamines, and CO. Polycondensation reactions were conducted in N,N-dimethylacetamide using a magnetic nanoparticles-bound Pd(II) complex [Fe3O4@SiO2-2P-PdCl2] as the catalyst and 1,8-diazabicycle[5,4,0]-7-undecene as the base at 120°, yielding poly(arylene ether sulfone amide)s having inherent viscosities of 0.43-0.77 dL/g. The resulting polymers were soluble in polar aprotic solvents and showed glass transition temperatures in the 204-265° range, with 10% weight losses occurring at temperatures >456° in N. Most of the polymers afforded transparent and tough films by solution-casting with tensile strengths of 71.8-82.2 MPa, Young’s moduli of 1.77-2.35 GPa, and elongations at break of 9.3-13.4%. More importantly, this supported Pd catalyst can facilely be separated from the product by simply using an external magnetic field and reused at least 7 times with almost consistent activity. The experimental process involved the reaction of 4,4′-Sulfonylbis(chlorobenzene)(cas: 80-07-9).Electric Literature of 80-07-9

The Article related to aromatic polyamide polyether polysulfone polymerization catalyst palladium magnetic nanoparticle, Chemistry of Synthetic High Polymers: Organic Condensation and Step Polymerization and other aspects.Electric Literature of 80-07-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics