Tag: 100-200

Halogen-rich halorhenates(IV): (Me₄N)₂{[ReX₆](X₂)} (X = Cl, Br) was written by Korobeynikov, Nikita A.;Usoltsev, Andrey N.;Sukhikh, Taisiya S.;Novikov, Alexander S.;Korolkov, Ilya V.;Fedin, Vladimir P.;Sokolov, Maxim N.;Adonin, Sergey A.. And the article was included in Polyhedron in 2022.SDS of cas: 75-57-0 The following contents are mentioned in the article:

Dihalogen – halorhenates(IV) (Me₄N)₂{[ReX₆](X₂)} (X = Cl 1, Br 2) were prepared and structurally characterized, featuring the 1st examples of Re/dihalogen supramol. complexes. 1 And 2 reveal pseudo-3D structure; both compounds demonstrate high thermal stability, releasing Cl₂ or Br₂ only at elevated temperatures (over 90 and 150°, resp.). The energies of halogen···halogen noncovalent interactions are â‰?.5 and 5.1 kcal/mol for 1 and 2, resp. Hirshfeld surface anal. was performed for both structures, allowing estimation of contributions of different noncovalent interactions to crystal packing. This study involved multiple reactions and reactants, such as Tetramethylammonium chloride (cas: 75-57-0SDS of cas: 75-57-0).

Tetramethylammonium chloride (cas: 75-57-0) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.SDS of cas: 75-57-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Selective Construction of Diverse Polycyclic Spirooxindoles via a Three-Component Reaction of Cyclic Mercapto-Substituted β-Enamino Esters, Isatins, and Cyclic 1,3-Diketones was written by Sun, Quan-Shun;Sun, Jing;Pan, Liu-Na;Yan, Chao-Guo. And the article was included in Journal of Organic Chemistry in 2020.Name: Ethyl 4-chloro-3-oxobutanoate The following contents are mentioned in the article:

The three-component reaction of alkyl 2-(benzo[b][1,4]thiazin-3-ylidene)acetates, isatins, and 1,3-indanedione (1,3-cyclopentanedione) in ethanol in the presence of acetic acid conveniently afforded spiro[indeno[1,2-b]phenothiazine-6,3′-indolines] or spiro[cyclopenta[b]phenothiazine-4,3′-indolines] in good yields and with high diastereoselectivity. More interestingly, a similar three-component reaction with 4-hydroxychromen-2-one resulted in the unexpected polycyclic spiro[benzo[b]chromeno[3′,4′:5,6]pyrano[2,3-e][1,4]thiazine-7,3′-indolines] in satisfactory yields. A plausible reaction mechanism was rationally proposed for formation of different kinds of the spiro compounds, and the stereochemistries of the various spiro compounds were clearly elucidated. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Name: Ethyl 4-chloro-3-oxobutanoate).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Name: Ethyl 4-chloro-3-oxobutanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

B(C₆F₅)₃-catalyzed synthesis of coumarins via Pechmann condensation under solvent-free conditions was written by Prajapti, Santosh Kumar;Rao, S. Prakash. And the article was included in Monatshefte fuer Chemie in 2021.Formula: C6H9ClO3 The following contents are mentioned in the article:

Tris(pentafluorophenyl)borane [B(C₆F₅)₃] catalyzed simple, efficient and environmentally benign protocol has been developed for the Pechmann condensation using variety of phenols and β-ketoesters under solvent-free conditions to afford coumarin derivatives The present protocol displayed significant advantages such as low catalyst loading, short reaction time, mild reaction conditions, low toxicity, easy work-up, high yields, and compatibility with other functional groups. In addition, it is a convenient, clean, and fast alternative approach for synthesizing variety of coumarin derivatives Moreover, the applicability of this method towards large-scale synthesis demonstrated its suitability for the industrial application. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Formula: C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Formula: C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facile Regioselective Synthesis of Novel bis-Thiazole Derivatives and Their Antimicrobial Activity was written by Mahmoodi, Nosrat O.;Parvizi, Jafar;Sharifzadeh, Bahman;Rassa, Mehdi. And the article was included in Archiv der Pharmazie (Weinheim, Germany) in 2013.Recommanded Product: 1-Bromo-6-chlorohexane The following contents are mentioned in the article:

The design and synthesis of several new bis[thiazole] derivatives serving as bis[drug] dimers in comparison with mono-heterocyclic analogs are described. These bis-drugs present superior medicinal and pharmacol. activities against both Gram-neg. (Pseudomonas aeruginosa and Escherichia coli) and Gram-pos. (Micrococcus luteus and Bacillus subtilis) bacteria, which are in general more sensitive to compounds with higher hydrophobicity. Compounds with higher hydrophobicity exhibited some activity against Gram-neg. bacteria. The synthesis of the target compounds was achieved by a cyclization of thiourea with (phenyl)ethanone dimer derivatives The title compounds thus formed included a thiazolamine dimer compound (I) and related substances. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Recommanded Product: 1-Bromo-6-chlorohexane).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Recommanded Product: 1-Bromo-6-chlorohexane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Theoretical and experimental investigation of NMR, IR and UV-visible spectra of hydroxyl-substituted-4-chloromethylcoumarin derivatives was written by Loarueng, Chutipapha;Boekfa, Bundet;Jarussophon, Suwatchai;Pongwan, Pawinee;Kaewchangwat, Narongpol;Suttisintong, Khomson;Jarussophon, Nongpanga. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2019.Electric Literature of C6H9ClO3 The following contents are mentioned in the article:

UV-Visible, FTIR and NMR exptl. and theor. spectral results have been compared for five substituted-4-chloromethylcoumarin derivatives (6-OH, 7-OH, 6,7-di-OH, 7,8-di-OH and 5,7-di-OH-substituted-4-chloromethylcoumarins). The theor. investigation was conducted using d. functional theory (DFT), namely the M06-2X functional form with 6-311 + G(2df,2p) basis set. The ¹³C-NMR and ¹H-NMR chem. shifts, vibrational spectra and MOs of the excited states were calculated based on their optimized geometries. The calculated values were found to have close agreement with the exptl. values. The theor. data are useful and could be important in the proper selection of compounds as intermediates for different chem. applications and modifications. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Electric Literature of C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A Fluorescent Probe for Neural Stem/Progenitor Cells with High Differentiation Capability into Neurons was written by Kim, Beomsue;Feng, Suihan;Yun, Seong-Wook;Leong, Cheryl;Satapathy, Rudrakanta;Wan, Si Yan Diana;Chang, Young-Tae. And the article was included in ChemBioChem in 2016.Name: 4-Chlororesorcinol The following contents are mentioned in the article:

Selection of a specific neural stem/progenitor cells (NSPCs) has attracted broad attention in regenerative medicine for neurol. disorders. Here, we report a fluorescent probe, CDg13, and its application for isolating strong neurogenic NSPCs. In comparison to the NSPCs isolated by other biomarkers, CDg13-stained NSPCs showed higher capability to differentiate into neurons. Target identification revealed that the fluorescence intensity of the probe within cells is inversely proportional to the expression levels of mouse and human Abcg2 transporters. These findings suggest that low Abcg2 expression is a biomarker for neurogenic NSPCs in mouse brain. Furthermore, CDg13 can be used to isolate Abcg2^low cells from heterogeneous cell populations. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Name: 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Name: 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organozinc Chemistry Enabled by Micellar Catalysis. Palladium-Catalyzed Cross-Couplings between Alkyl and Aryl Bromides in Water at Room Temperature was written by Duplais, Christophe;Krasovskiy, Arkady;Lipshutz, Bruce H.. And the article was included in Organometallics in 2011.Computed Properties of C6H12BrCl The following contents are mentioned in the article:

Negishi-like cross-couplings between (functionalized) alkyl and aryl bromides are described. Despite the fact that organozinc reagents are intolerant of water, their formation as well as their use in an aqueous micellar environment is discussed herein. Each component of this complex series of events leading up to C-C bond formation has an important role which has been determined insofar as the type of zinc, amine ligand, surfactant, and palladium catalyst are concerned. In particular, the nature of the surfactant has been found to be crucial in order to obtain synthetically useful results involving highly reactive, moisture-sensitive organometallics. Neither organic solvent nor heat is required for these cross-couplings to occur; just add water. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Computed Properties of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cyclization of 1-(4,4-diethoxybutyl)-3-arylureas: a case study was written by Smolobochkin, Andrey V.;Gazizov, Almir S.;Voronina, Julia K.;Burilov, Alexander R.;Pudovik, Michail A.. And the article was included in Monatshefte fuer Chemie in 2018.Safety of 4-Chlororesorcinol The following contents are mentioned in the article:

The study on the reaction of (4,4-diethoxybutyl)ureas with nucleophilic aromatics was reported herein. It was found that the structure of the products mainly depends on the strength of the acid used as catalyst as well as aromatic nucleophile nature and its concentration Either 2-arylpyrrolidines e.g., (R,S)-2,2′-(4,6-Dihydroxy-5-methyl-1,3-phenylene)bis[N-(naphthalen-1-yl)pyrrolidine-1-carboxamide], diarylbutanes, 1-[4,4-Bis(5-chloro-2,4-dihydroxyphenyl)butyl]-3-(naphthalen-1-yl)urea, bispyrrole derivatives, N-(Naphthalen-1-yl)-4-[1-(naphthalen-1-ylcarbamoyl)pyrrolidin-2-yl]-2,3-dihydro-1H-pyrrole-1-carboxamide, or pyrrolidinequinazolinones can be synthesized via variation of these factors. The proposed mechanism of the reaction is discussed. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Safety of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Safety of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and Antibacterial Evaluation of Thiouracil Derivatives Containing 1,2,4-Triazolo[1,5-a]Pyrimidine was written by Cui, Penglei;Zhang, Di;Guo, Xiumin;Ji, Shujing;Jiang, Qingmei. And the article was included in Letters in Organic Chemistry in 2021.Name: Ethyl 4-chloro-3-oxobutanoate The following contents are mentioned in the article:

A series of new thiouracil compounds containing 1,2,4-triazolo[1,5-a]pyrimidines I (R¹ = 4-Cl, 3,4-Cl₂, 3,4,5-Cl₃; R² = H, 2-Cl, 4-Cl, 4-Ph, 2,4-Cl₂) was designed and synthesized. The in vitro antibacterial activities of the new compounds I against Bacillus amyloliquefaciens, Staphylococcus aureus and Bacillus subtilis were tested. The results showed that some of the new compounds had strong inhibitory activities against the tested bacteria. At the concentration of 50μg/mL, the compound I (R¹ = 4-Cl, R² = 2,4-Cl₂) had broad and highest inhibitory activity with the 100% inhibition against the three tested strains, the same as norfloxacin which was used as the control. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Name: Ethyl 4-chloro-3-oxobutanoate).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Name: Ethyl 4-chloro-3-oxobutanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Construction and investigation of photo-switch property of azobenzene-bridged pillar[5]arene-based [3]rotaxanes was written by Chong, Hui;Nie, Cuiyun;Wang, Lihong;Wang, Sicong;Han, Ying;Wang, Yang;Wang, Chengyin;Yan, Chaoguo. And the article was included in Chinese Chemical Letters in 2021.Electric Literature of C6H12BrCl The following contents are mentioned in the article:

Series of azobenzene-bridged pillar[5]arene-based [3]rotaxanes with different alkyl chain length of guest mols. were constructed by threading-endcapping method with alkylenetriazole as axile and tetrahydrochromene as endcapping group. The encapsulation of pillar[5]arenes were proved by high-resolution mass, ¹H NMR and NOESY spectra. The photo-responsive property were examined by irradiation of the synthesized [3]rotaxanes with 365 nm and blue light LED, which caused trans to cis and cis to trans isomerization, resp. Irradiation of corresponding model guest compounds without pillar[5]arene encapsulation resulted in near completely trans to cis and cis to trans isomerization, indicating the existence of pillar[5]arenes is the determining factor for the comprised photo isomerization efficiency. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Electric Literature of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Electric Literature of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics