Tag: 100-200

Zhang, Yan; Lin, Zhipeng; Ackermann, Lutz published their research in Chemistry – A European Journal in 2021. The article was titled 《Electrochemical C-H Amidation of Heteroarenes with N-Alkyl Sulfonamides in Aqueous Medium》.Name: Thiophene-2-sulfonyl chloride The article contains the following contents:

The construction of C-N bonds by free radical reactions represents a powerful synthetic approach for direct C-H amidations of arenes or heteroarenes. Developing efficient and more environmentally friendly synthetic methods for C-H amidation reactions remains highly desirable. Herein, metal-free electrochem. oxidative dehydrogenative C-H amidations of heteroarenes with N-alkylsulfonamides have been accomplished. The catalyst- and chem.-oxidant-free C-H amidation features an ample scope and employs electricity as the green and sole oxidant. A variety of heteroarenes, including indoles, pyrroles, benzofuran and benzothiophene, thereby underwent this C(sp2)-H nitrogenation. Cyclic voltammetry studies and control experiments provided evidence for nitrogen-centered radicals being directly generated under metal-free electrocatalysis. In the experiment, the researchers used many compounds, for example, Thiophene-2-sulfonyl chloride(cas: 16629-19-9Name: Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Name: Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhu, Baoxiang; Wang, Zhao; Xi, Hui; Feng, Zengqiang; Wang, Binglei; Jiao, Wenyang; Li, Zhongxian; Wang, Zechao; Wu, Junliang published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Visible-light-promoted divergent functionalizations of methylenecyclopropanes》.COA of Formula: C4H3ClO2S2 The article contains the following contents:

Simple and convenient visible-light-promoted radical monofunctionalization and difunctionalization of methylenecyclopropanes via ring-opening and cyclization processes was developed for the syntheses of difluoromethyl compounds, alkyl compounds, halides, and sulfonyl compounds e.g., I in moderate to excellent yields. The methodologies feature a wide substrate scope and tolerate various functional groups. A possible radical mechanism was investigated and proven as a single electron transfer (SET) procedure.Thiophene-2-sulfonyl chloride(cas: 16629-19-9COA of Formula: C4H3ClO2S2) was used in this study.

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. COA of Formula: C4H3ClO2S2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Copper-Catalyzed Cross-Coupling of Benzylic Bromides with Arylboronic Acids: Synthesis of Diarylalkanes and Preliminary Antifungal Evaluation Against Magnaporthe Grisea》 was published in Asian Journal of Organic Chemistry in 2020. These research results belong to Zhu, Zhu; Liu, Jinggong; Dong, Shoucheng; Chen, Bolai; Wang, Zhenghui; Tang, Ri-yuan; Li, Zhaodong. HPLC of Formula: 768-35-4 The article mentions the following:

Reported herein is the practical synthesis of 1,1-diarylalkanes motifs via copper-catalyzed cross-coupling reaction of benzylic bromides with arylboronic acids under mild conditions. The protocols show broad scope and good functional group tolerance, and are also applicable to complex natural products. Mechanistic study indicates a radical mechanism. Moreover, preliminary antibacterial evaluation against Magnaporthe grisea is also described for the first time. In the experimental materials used by the author, we found (3-Fluorophenyl)boronic acid(cas: 768-35-4HPLC of Formula: 768-35-4)

(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.HPLC of Formula: 768-35-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Palladium Catalyzed Aminocarbonylation of Benzylic Ammonium Triflates with Nitroarenes: Synthesis of Phenylacetamides》 was written by Yang, Li-Miao; Li, Shan-Shan; Zhang, You-Ya; Lu, Jin-Liang; Deng, Jing-Tong; Ma, Ai-Jun; Zhang, Xiang-Zhi; Zhang, Shu-Yu; Peng, Jin-Bao. Recommanded Product: 350-30-1 And the article was included in Advanced Synthesis & Catalysis on April 17 ,2021. The article conveys some information:

A palladium catalyzed reductive aminocarbonylation of benzylic ammonium triflates with nitroarenes for the synthesis of phenylacetamides was developed. Using Pd(acac)2/DPPF catalyst system, a range of different substituted phenylacetamides were prepared in moderate to good yields from benzylic ammonium triflates and nitroarenes through Csp3-N bond cleavage. A variety of alkyl, aryl, and halide substituents on both substrates was used, and many useful functional groups were tolerated. In the experiment, the researchers used many compounds, for example, 3-Chloro-4-fluoronitrobenzene(cas: 350-30-1Recommanded Product: 350-30-1)

3-Chloro-4-fluoronitrobenzene(cas: 350-30-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Recommanded Product: 350-30-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Product Details of 768-35-4In 2019 ,《From Tetrahydrofurans to Tetrahydrobenzo[d]oxepines via a Regioselective Control of Alkyne Insertion in Rhodium-Catalyzed Arylative Cyclization》 was published in Journal of Organic Chemistry. The article was written by Selmani, Aymane; Serpier, Fabien; Darses, Sylvain. The article contains the following contents:

The formation of chiral 5- and 7-membered tetrahydrofurans and tetrahydrobenzo[d]oxepines is achieved via arylative cyclization of simple O-tethered alkyne-enoates in the presence of arylboronic acids and chiral dienes-rhodium catalyst under mild conditions. Access to such structures was achieved via a simple switch in the regioselectivity of the alkyne insertion thanks to a proper choice of the alkyne substituent. In the experiment, the researchers used (3-Fluorophenyl)boronic acid(cas: 768-35-4Product Details of 768-35-4)

(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Product Details of 768-35-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhou, Nengneng; Kuang, Kaimo; Wu, Meixia; Wu, Sixin; Xia, Ziqin; Xu, Qiankun; Zhang, Man published their research in Organic Chemistry Frontiers in 2021. The article was titled 《Visible-light-induced radical cascade cyclization of 1-(allyloxy)-2-(1-arylvinyl)benzenes with sulfonyl chlorides for the synthesis of sulfonated benzoxepines》.SDS of cas: 16629-19-9 The article contains the following contents:

A visible light photocatalyzed cascade sulfonylation/cyclization of 1-(allyloxy)-2-(1-arylvinyl)benzenes I (X = O; R1 = H, 4-F, 5-Me, 3,4-benzo, etc.; R2 = Ph, 2-MeC6H4, 4-BrC6H4, etc.; R3 = H, Me) and their analogs I (X = CH2, NTs; R1 = R3 = H; R2 = Ph) with sulfonyl chlorides R4SO2Cl (R4 = Me, cyclopropyl, 4-MeC6H4, 1-naphthyl, 2-thienyl, etc.) for the construction of sulfonated benzoxepines and analogs II has been developed. In the presence of Eosin Y (2.0 mol%) as a photocatalyst and Na2CO3 as a base, the reactions proceed smoothly to afford seven-membered rings in good yields. This transformation features wide substrate scope, the use of easily accessible materials and excellent functional group tolerance. After reading the article, we found that the author used Thiophene-2-sulfonyl chloride(cas: 16629-19-9SDS of cas: 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. SDS of cas: 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Application of high-throughput competition experiments in the development of aspartate-directed site-selective modification of tyrosine residues in peptides》 was written by Chinn, Alex J.; Hwang, Jaeyeon; Kim, Byoungmoo; Parish, Craig A.; Krska, Shane W.; Miller, Scott J.. Recommanded Product: 5781-53-3 And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

Herein we report a Cu-catalyzed, site-selective functionalization of peptides that employs an aspartic acid (Asp) as a native directing motif, which directs the site of O-arylation at a proximal tyrosine (Tyr) residue. Through a series of competition studies conducted in high-throughput reaction arrays, effective conditions were identified that gave high selectivity for the proximal Tyr in Asp-directed Tyr modification. Good levels of site-selectivity were achieved in the O-arylation at a proximal Tyr residue in a number of cases, including a peptide-small mol. hybrid.Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Recommanded Product: 5781-53-3) was used in this study.

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Recommanded Product: 5781-53-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis and characterization of Pd based on [2,2′- bipyridin]-4-amine functionalized nano cellulose as a novel and recyclable nano catalyst for Suzuki reaction》 was written by Sun, Yuqi; Mohammadnia, Majid. Synthetic Route of C6H6BFO2 And the article was included in Inorganic Chemistry Communications in 2020. The article conveys some information:

In this work, it was designed and prepared an efficient nanocatalyst Pd based on [2,2′- bipyridin]-4-amine functionalized nano cellulose (Pd@BPA@CNC) and then characterized by FT-IR, XRD, ICP-AES, EDX, SEM, TEM and TGA techniques. The catalytic activity of the nanocatalyst was investigated through one-pot synthesis of biaryl derivatives from the reaction of aryl halides with arylboronic acids in DMSO solvent conditions. This Simple and mild procedure displayed excellent recyclability and provided cleaner conversion in a short reaction time. All of these advantages make the protocol feasible and economical attractive for researchers. In addition to this study using (3-Fluorophenyl)boronic acid, there are many other studies that have used (3-Fluorophenyl)boronic acid(cas: 768-35-4Synthetic Route of C6H6BFO2) was used in this study.

(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Synthetic Route of C6H6BFO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Regioselective Chloro-thiolation of Alkenes with Sulfonyl Chlorides》 was published in Journal of Organic Chemistry in 2020. These research results belong to Wei, Jingjing; Liang, Shuaishuai; Jiang, Lvqi; Mumtaz, Yasir; Yi, Wen-bin. Recommanded Product: Thiophene-2-sulfonyl chloride The article mentions the following:

A newly developed sulfonyl chlorides-based regioselective chloro-thiolation of alkenes has been disclosed, the reaction is compatible with a variety of functional groups and can be scaled up to the gram-scale with no loss in yield. The employment of readily available reactants, mild reaction conditions, and high regioselectivity makes this process very practical. Mechanistic studies revealed a possible free radical reaction pathway. The experimental part of the paper was very detailed, including the reaction process of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Recommanded Product: Thiophene-2-sulfonyl chloride)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Recommanded Product: Thiophene-2-sulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Cu-Catalyzed Direct C7 Sulfonylation of Indolines with Arylsulfonyl Chlorides》 was published in Journal of Organic Chemistry in 2020. These research results belong to Zhi, Changlei; Wang, Qiuling; Liu, Shuang; Xue, Yuting; Shi, Linlin; Zhu, Xinju; Hao, Xin-Qi; Song, Mao-Ping. Product Details of 16629-19-9 The article mentions the following:

An efficient Cu-catalyzed direct sulfonylation of indolines with easily accessible sulfonyl chlorides has been realized under an air atm. via a chelation-assisted strategy. This protocol exhibits several unique characteristics, including broad substrate scope, good functional group tolerance, and operational convenience, which enable a regioselective access to a variety of C-7 functionalized indoline scaffolds in moderate to good yields. The mechanistic study reveals that the sulfonyl radical might be involved in this transformation. The experimental process involved the reaction of Thiophene-2-sulfonyl chloride(cas: 16629-19-9Product Details of 16629-19-9)

Thiophene-2-sulfonyl chloride(cas: 16629-19-9) is a member of sulfonyl chlorides. Sulfonyl chlorides are reactive sulfonic acid derivatives similar in properties and reactivity to acid chlorides of carboxylates. The sulfonic acid group, however, is a highly hindered molecule, containing a tetrahedral configuration of substituents. Product Details of 16629-19-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics