Tag: 100-200

On April 27, 2022, Liu, Jingbo; Shi, Yabing; Tian, Zhicheng; Li, Fengyun; Hao, Zesheng; Wen, Wen; Zhang, Li; Wang, Yuanhong; Li, Yuxin; Fan, Zhijin published an article.Safety of 2-Amino-4-chlorobenzoic acid The title of the article was Bioactivity-Guided Synthesis Accelerates the Discovery of Evodiamine Derivatives as Potent Insecticide Candidates. And the article contained the following:

Pests threaten worldwide food security by decreasing crop yields and damaging their quality. Natural product-based mol. design and structural optimization have been one of the most effective ways to innovate pesticides for integrated insect management. To continue our previous studies on the discovery of insecticidal lead, a series of evodiamine derivatives were designed, synthesized, and evaluated for their insecticidal activities. The bioassay results demonstrated that compounds (I) and (II) exhibited 90 and 80% insecticidal activities against Mythimna separata at 2.5 mg/L, resp., which were superior to evodiamine (10% at 10 mg/L), matrine (45% at 600 mg/L), and rotenone (30% at 200 mg/L). Compounds I, II and (III) showed 90% insecticidal activities against Plutella xylostella at 1.0 mg/L, far more potent than those of evodiamine, matrine, and rotenone. Compound I displayed 60% insecticidal activity against Helicoverpa armigera at 5.0 mg/L, while evodiamine, matrine, and rotenone showed very poor activities. The study on the insecticidal mechanism of action by a calcium imaging experiment indicated that the insect ryanodine receptors (RyRs) could be the potential target of I. Furthermore, the mol. docking indicated that I anchored in the binding site of the RyR of P. xylostella. The above results manifested the potential of evodiamine derivatives as potent insecticide candidates. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Safety of 2-Amino-4-chlorobenzoic acid

The Article related to evodiamine derivative preparation insecticide mythimna plutella helicoverpa ryanodine receptor, evodiamine, insecticidal activity, insecticidal mechanism of action, molecular docking, structure−activity relationship and other aspects.Safety of 2-Amino-4-chlorobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 20, 2012, Uthuppu, Basil; Aamand, Jens; Joergensen, Claus; Kiersgaard, Spire M.; Kostesha, Natalie; Jakobsen, Mogens Havsteen published an article.Recommanded Product: Methyl 6-chloro-6-oxohexanoate The title of the article was Optimization of an immunoassay of 2,6-dichlorobenzamide (BAM) and development of regenerative surfaces by immunosorbent modification with newly synthesized BAM hapten library. And the article contained the following:

Dichlobenil is an extensively used herbicide worldwide which is transformed to the mobile 2,6-dichlorobenzamide (BAM) in soil. BAM has been found in many European groundwater resources that are exploited for drinking water. Currently, immunoassay based monitoring technique (plate based ELISA) is being employed to quant. detect BAM in water samples. As a starting step of developing immunoassay based on-site monitoring systems for pesticide anal., the heterogeneous BAM immunoassay is optimized in terms of surface (polymer) regeneration. We synthesized a small library of BAM haptens which are slightly different in chem. structures, immobilized them on surfaces and compared the affinity constants of the monoclonal antibody HYB 273 towards them. By using ELISA technol., we also checked the regeneration potentials of the haptens, correlated these results to the affinity constants and found that BAM hapten with an intermediate affinity has better regeneration potential. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Recommanded Product: Methyl 6-chloro-6-oxohexanoate

The Article related to optimization immunoassay dichlorobenzamide regenerative surface immunosorbent modification synthesized hapten, immunoassay dichlorobenzamide regenerative surface immunosorbent modification synthesized hapten library and other aspects.Recommanded Product: Methyl 6-chloro-6-oxohexanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 28, 1983, Fray, M. Jonathan; Thomas, Eric J.; Wallis, John D. published an article.HPLC of Formula: 5034-06-0 The title of the article was On the stereoselectivity of epoxide formation using dimethyloxosulfonium methylide. X-ray structure of (5SR)-5-[(1RS)-1-methyl-2-oxacyclopropyl]pyrrolidin-2-one. And the article contained the following:

Epoxidation of 5-acetylpyrrolidin-2-one with dimethyloxosulfonium methylide in THF at 20° for 2 h and then 55° for 1 h gave a 78:22 mixture of epoxides I (α-Me, β-Me) (II and III, resp.) whereas in the presence of ZnCl2 a 23:77 mixture of II and III was obtained. The configuration of these epoxides was determined from the NMR spectra of the corresponding carbonate derivatives IV and by x-ray crystallog. anal. of III. The experimental process involved the reaction of trimethyloxosulphonium chloride(cas: 5034-06-0).HPLC of Formula: 5034-06-0

The Article related to epoxidation acetylpyrrolidinone stereoselectivity, pyrrolidinone acetyl epoxidation stereoselectivity, methyloxiranylpyrrolidinone preparation configuration crystal structure, oxiranylpyrrolidinone methyl structure and other aspects.HPLC of Formula: 5034-06-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 28, 1990, Lin, Ivan J. B.; Lai, J. S.; Liu, C. W. published an article.COA of Formula: C3H9ClOS The title of the article was Phase-transfer-catalyzed phosphorus-carbon bond cleavage in platinum bis(diphenylphosphino)methane complexes under exceedingly mild conditions. And the article contained the following:

The reaction of [Pt(dppm)Cl2] (dppm = Ph2PCH2PPh2) with [S(O)Me3]Cl under basic phase-transfer-catalyzed conditions gave the complex {Pt(PPh2Me)[PPh2(OH)][(CH2)2S(O)Me]}Cl, which contains a bidentate sulfur ylide and two monodentate phosphine ligands. The latter was produced by the facile base hydrolysis of the dppm ligand, a reaction that is general for other Pt-dppm complexes. The experimental process involved the reaction of trimethyloxosulphonium chloride(cas: 5034-06-0).COA of Formula: C3H9ClOS

The Article related to carbon phosphorus bond cleavage bisdiphenylphosphinomethane, platinum bisdiphenylphosphinomethane ligand base hydrolysis, sulfur ylide platinum complex, phase transfer catalysis bisdiphenylphosphinomethaneplatinum and other aspects.COA of Formula: C3H9ClOS

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 22, 1986, Fukuoka, Shinsuke published a patent.Recommanded Product: 4-Chloro-2-fluorotoluene The title of the patent was Aryl fluorobenzoates. And the patent contained the following:

The title esters, useful as intermediates for agrochems., polymers, and pharmaceuticals (no data), are prepared by reaction of fluorinated aromatic halides with CO and aromatic hydroxy compounds over Pd compounds and phosphine catalysts in the presence of bases. Thus, CO was pressurized into a mixture of p-FC6H4Br 17.5, PhOH 11.3, Bu3N 22.2, Ph3P 0.4, and PdCl2 0.04 g at 30 kg/cm2 and heated at 200° to give 98% p-FC6H4CO2Ph with 99% conversion. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Recommanded Product: 4-Chloro-2-fluorotoluene

The Article related to aryl fluorobenzoate preparation intermediate agrochem, fluorobenzene aryloxycarbonylation catalyst, pharmaceutical intermediate aryl fluorobenzoate preparation, polymer intermediate aryl fluorobenzoate preparation and other aspects.Recommanded Product: 4-Chloro-2-fluorotoluene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 5, 2020, Raza, Abdul Rauf; Nisar, Bushra; Khalid, Muhammad; Gondal, Humaira Yasmeen; Khan, Muhammad Usman; Morais, Sara Figueiredo de Alcantara; Tahir, Muhammad Nawaz; Braga, Ataualpa Albert Carmo published an article.Quality Control of 2-Amino-4-chlorobenzoic acid The title of the article was A facile microwave assisted synthesis and structure elucidation of (3R)-3-alkyl-4,1-benzoxazepine-2,5-diones by crystallographic, spectroscopic and DFT studies. And the article contained the following:

The use of microwave (MW) irradiation in organic synthesis has become increasingly popular within the pharmaceutical and academic arenas because it is a new enabling technol. for drug discovery and development. It is a rapid way of synthesis, which involves faster reaction rates and high selectivity to conventional heating method of syntheses. The MW-assisted 7-exo-tet cyclization of N-acylanthranilic acids afforded (3R)-3-alkyl-4,1-benzoxazepines-2,5-diones in very short duration (20 min) with extraordinary high yields in comparison to conventional heating mode of synthesis. The method development, comparative yields of MW-assisted and thermal method of syntheses, crystallog., spectroscopic and d. functional theory (DFT) studies are reported herein. Four novel compounds I and II [R1 = iBu, R2 = Ph, X = Y = Z = H; R1 = iPr, R2 = H; X = Cl, Y = H, Z = Me; R1 = iPr, R2 = H, X = Z = Br, Y = H] were synthesized, validated by 1HNMR, 13CNMR, FT-IR, UVVis, EIMS spectroscopic techniques and confirmed by using single crystal X-ray diffraction (SC-XRD) study. The DFT and TDDFT calculations at B3LYP/6-311 + G(d,p) level of theory were performed for comparative anal. of spectroscopic data, optimized geometries, frontier MOs (FMOs), natural bond orbital (NBO) anal. and nonlinear optical (NLO) properties of I and II. Overall, exptl. findings were supported nicely by corresponding DFT computed results. The NBO anal. confirmed that the presence of non-covalent interactions, hydrogen bonding and hyper- conjugative interactions are pivotal cause for the existence of I and II in the solid-state. NLO anal. showed that I and II have significant NLO properties as compared to prototype standard compound which disclosed their potential for technol. related applications. The experimental process involved the reaction of 2-Amino-4-chlorobenzoic acid(cas: 89-77-0).Quality Control of 2-Amino-4-chlorobenzoic acid

The Article related to microwave synthesis crystal structure elucidation alkylbenzoxazepinedione, (3r)-3-alkyl-4,1-benzoxazepine-2,5-diones, chiral pool approach, dft, microwave irradiation, n-acylanthranilic acids, spectroscopic data and other aspects.Quality Control of 2-Amino-4-chlorobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 31, 2015, Hu, Peng; Bach, Thorsten published an article.SDS of cas: 35444-44-1 The title of the article was Synthesis of Alkyl-Substituted Pyridines by Directed Pd(II)-Catalyzed C-H Activation of Alkanoic Amides. And the article contained the following:

A general alkylation protocol for substituted iodopyridines was developed, e.g., I, (32 examples, 44-97% yield). The reaction is based on the Pd(II)-catalyzed C-H activation of 8-aminoquinoline-derived alkanoic amides and it employs a catalyst cocktail of Pd(OAc)2 (10 mol%), NaI (30 mol%), and (BuO)2POOH (20 mol%), with Ag2CO3 as base. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).SDS of cas: 35444-44-1

The Article related to alkyl pyridine aminoquinoline alkanoic amide preparation, infractin preparation, dihydrocanthinone preparation, iodo carboline alkylation, aminoquinoline alkanoic amide iodopyridine alkylation palladium catalyst and other aspects.SDS of cas: 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 28, 2013, Ono, Yohei; Shiren, Kazushi; Kageyama, Akiko published a patent.Category: chlorides-buliding-blocks The title of the patent was Benzofluorenes bearing diarylamino and 9-carbazolyl groups, materials containing them for emitter layers of organic electroluminescent devices, and displays and lighting systems. And the patent contained the following:

The title benzofluorenes are represented by I [R = C1-6 alkyl, C3-6 cycloalkyl, (C1-4 alkyl-substituted) C6-24 aryl, (C1-4 alkyl-substituted) C5-24 heteroaryl; one of A and B = (substituted) 9-carbazolyl, the other of A and B = diarylamino]. The title organic electroluminescent devies, preferably, blue-emitting, show high color saturation and long service life. Preferable substances for electron-transporting layers and/or electron-injecting layers of the devices are also disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Category: chlorides-buliding-blocks

The Article related to carbazolyl diarylamino benzofluorene organic electroluminescent device, electroluminescent display carbazolyl diarylamino benzofluorene, lighting system electroluminescent carbazolyl diarylamino benzofluorene and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 10, 2013, Ono, Yohei; Shiren, Kazushi; Kageyama, Akiko published a patent.Product Details of 38939-88-7 The title of the patent was Benzofluorenes bearing diarylamino and 9-carbazolyl groups, materials containing them for emitter layers of organic electroluminescent devices, and displays and lighting systems. And the patent contained the following:

The title benzofluorenes are represented by I [R = C1-6 alkyl, C3-6 cycloalkyl, (C1-4 alkyl-substituted) C6-24 aryl, (C1-4 alkyl-substituted) C5-24 heteroaryl; one of A and B = (substituted) 9-carbazolyl, the other of A and B = diarylamino]. The title organic electroluminescent devies, preferably, blue-emitting, show high color saturation and long service life. Preferable substances for electron-transporting layers and/or electron-injecting layers of the devices are also disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Product Details of 38939-88-7

The Article related to carbazolyl diarylamino benzofluorene organic electroluminescent device, electroluminescent display carbazolyl diarylamino benzofluorene, lighting system electroluminescent carbazolyl diarylamino benzofluorene and other aspects.Product Details of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 1, 2010, Sun, Ranfeng; Li, Yongqiang; Lue, Maoyun; Xiong, Lixia; Wang, Qingmin published an article.Related Products of 38939-88-7 The title of the article was Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group. And the article contained the following:

A series of new structural benzoylphenylureas (BPUs) containing oxime ether and oxime ester groups, e.g. I [R = i-Pr, PhCH2, R1 = Me; R = C(O)Me, C(O)Ph, R1 = H] were designed and synthesized. The larvicidal activities of these benzoylphenylureas against Oriental armyworm and mosquito were evaluated and the results of the bioassay displayed a specific structure-activity relationship (SAR). Most of the compounds exhibited excellent larvicidal activities against Oriental armyworm and mosquito. Interestingly, some compounds showed a different structure-activity relationship towards diamondback moth, beet armyworm, and corn borer even though the three tested insects all belong to the same insect order. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Related Products of 38939-88-7

The Article related to benzoylphenylurea oxime ether ester preparation larvicidal activity sar, larvicidal benzoylphenylurea sar oriental armyworm mosquito, sar benzoylphenylurea toxicity diamondback moth beet armyworm corn borer and other aspects.Related Products of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics