Tag: 100-200

Bisht, Ranjana et al. published their research in Angewandte Chemie, International Edition in 2018 | CAS: 1711-11-1

3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1711-11-1

Amide Effects in C-H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides was written by Bisht, Ranjana;Hoque, Emdadul Md;Chattopadhyay, Buddhadeb. And the article was included in Angewandte Chemie, International Edition in 2018.SDS of cas: 1711-11-1 This article mentions the following:

Borylated aromatic amides 3-pinBC6H4-nXnCONR2 (6a–t; X = halo, CN, Ph, benzo, MeO) were prepared by meta C-H activation/borylation of amides XnC6H5-nCONR2 with B2pin2, catalyzed by [Ir2(cod)2(渭-OMe)2]/L1 with up to 99% regioselectivity. A new concept for the meta-selective iridium-catalyzed borylation of aromatic amides is described. It has been demonstrated that while esters gave para-borylated products, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand I (L1) has been employed and engages in an O…K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for providing up to 99% selective formation of meta-borylated products. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1SDS of cas: 1711-11-1).

3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1711-11-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Lee, Hyo-Jun et al. published their research in Organic & Biomolecular Chemistry in 2018 | CAS: 697-73-4

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 697-73-4

Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization was written by Lee, Hyo-Jun;Eun, Bora;Sung, Eonseon;Hwang, Gil Tae;Ko, Young Kwan;Cho, Chang-Woo. And the article was included in Organic & Biomolecular Chemistry in 2018.Product Details of 697-73-4 This article mentions the following:

An efficient quinidine-based phase-transfer-catalyzed enantioselective cascade oxa-Michael-cyclization reaction of hydroxylamine with various 尾-carboxy-substituted 伪,尾-unsaturated ketones has been achieved for the preparation of chiral carboxy-substituted 2-isoxazolines. This cascade reaction provided the desired products in good yields (up to 98%) with excellent enantioselectivities (91-96% ee). In addition, the cascade reaction was effectively applied to the first catalytic asym. synthesis of the herbicide (S)-methiozolin. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Product Details of 697-73-4).

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 697-73-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sehgal, R. K. et al. published their research in Liebigs Annalen der Chemie in 1991 | CAS: 7476-66-6

Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Category: chlorides-buliding-blocks

Novel photocycloadditions of electron-deficient nitrones to 2-methyl-2-butene was written by Sehgal, R. K.;Griffin, G. W.. And the article was included in Liebigs Annalen der Chemie in 1991.Category: chlorides-buliding-blocks This article mentions the following:

Irradiation of (E)-PhN(O):CPhR (I; R = CN, CO2Me) with Me2C:CHMe gave oxazolidines in which O became attached to the less substituted terminus of the olefin. The oxazolidines from I (R = CO2Me) could be isolated, but those from I (R = CN) were more labile and underwent ionization to an oxazolinium ion, followed by nucleophilic attack by CN– and ring opening, to give PhC(:NPh)OCHMeCMe2CN. Mechanisms were discussed. In the experiment, the researchers used many compounds, for example, Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6Category: chlorides-buliding-blocks).

Methyl 2-chloro-2-phenylacetate (cas: 7476-66-6) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Przytycka, Roza et al. published their research in Roczniki Chemii in 1954 | CAS: 3438-16-2

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Reference of 3438-16-2

Synthesis of 2-methoxy-5-chlorobenzoic acid and its ethyl ester was written by Przytycka, Roza;Malinowski, Stanislaw;Wirecka, Elzbieta. And the article was included in Roczniki Chemii in 1954.Reference of 3438-16-2 This article mentions the following:

Reduction of 2,4-O2N(Cl)C6H3OMe with Fe and HCl gave 71% 2,4-H2N(Cl)C6H3OMe, which treated with NaNO2 and HCl, and then with Cu2(CN)2 gave 82% 2,5-MeO(Cl)C6H3CN (I), m. 99-100掳 (from alc.). Heating I in a water-alc. solution of NaOH gave 51% 2,5-MeO(Cl)C6H3CO2H, m. 77-9掳 (from alc.), which heated in an excess of EtOH in the presence of H2SO4 gave 58.8% 2,5-MeO(Cl)C6H3CO2Et, m. 98-100掳 (from EtOAc). In the experiment, the researchers used many compounds, for example, 5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2Reference of 3438-16-2).

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Reference of 3438-16-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Coskun, Necdet et al. published their research in Synthetic Communications in 1997 | CAS: 6834-42-0

2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: 2-(3-Methoxyphenyl)acetyl chloride

Reactivity of benzylic acylammonium chlorides. A novel method for the synthesis of N-phenacylamides was written by Coskun, Necdet;Tirli, Fatma. And the article was included in Synthetic Communications in 1997.Name: 2-(3-Methoxyphenyl)acetyl chloride This article mentions the following:

Tertiary amines R1C6H4CH2NR2CH2COC6H4R3-4 [R1 = H, 2,3-(MeO)2, 3,4-(MeO)2, 2-NO2, etc., R2 = Me, PhCH2, 3,4-(MeO)2C6H3CH2, R3 = H, MeO] reacted with acid chlorides R4COCl [R4 = 3-MeOC6H4CH2, 3,4-(MeO)2C6H4CH2, PhCH2, 4-MeOC6H4CH2] to give corresponding benzyl chlorides and N-phenacylamides R4CONR2CH2COC6H4R3-4. The effect of the substituents in the benzyl group on the reactivity of the intermediate acylammonium chlorides was investigated. In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0Name: 2-(3-Methoxyphenyl)acetyl chloride).

2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: 2-(3-Methoxyphenyl)acetyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Bisht, Ranjana et al. published their research in Angewandte Chemie, International Edition in 2018 | CAS: 1711-11-1

3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1711-11-1

Amide Effects in C-H Activation: Noncovalent Interactions with L-Shaped Ligand for meta Borylation of Aromatic Amides was written by Bisht, Ranjana;Hoque, Emdadul Md;Chattopadhyay, Buddhadeb. And the article was included in Angewandte Chemie, International Edition in 2018.SDS of cas: 1711-11-1 This article mentions the following:

Borylated aromatic amides 3-pinBC6H4-nXnCONR2 (6a–t; X = halo, CN, Ph, benzo, MeO) were prepared by meta C-H activation/borylation of amides XnC6H5-nCONR2 with B2pin2, catalyzed by [Ir2(cod)2(μ-OMe)2]/L1 with up to 99% regioselectivity. A new concept for the meta-selective iridium-catalyzed borylation of aromatic amides is described. It has been demonstrated that while esters gave para-borylated products, amides lead to meta borylations. For achieving high meta selectivity, an L-shaped bifunctional ligand I (L1) has been employed and engages in an O…K noncovalent interaction with the oxygen atom of the moderately distorted amide carbonyl group. This interaction provides exceptional control for providing up to 99% selective formation of meta-borylated products. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1SDS of cas: 1711-11-1).

3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.SDS of cas: 1711-11-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Lee, Hyo-Jun et al. published their research in Organic & Biomolecular Chemistry in 2018 | CAS: 697-73-4

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 697-73-4

Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization was written by Lee, Hyo-Jun;Eun, Bora;Sung, Eonseon;Hwang, Gil Tae;Ko, Young Kwan;Cho, Chang-Woo. And the article was included in Organic & Biomolecular Chemistry in 2018.Product Details of 697-73-4 This article mentions the following:

An efficient quinidine-based phase-transfer-catalyzed enantioselective cascade oxa-Michael-cyclization reaction of hydroxylamine with various β-carboxy-substituted α,β-unsaturated ketones has been achieved for the preparation of chiral carboxy-substituted 2-isoxazolines. This cascade reaction provided the desired products in good yields (up to 98%) with excellent enantioselectivities (91-96% ee). In addition, the cascade reaction was effectively applied to the first catalytic asym. synthesis of the herbicide (S)-methiozolin. In the experiment, the researchers used many compounds, for example, 2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4Product Details of 697-73-4).

2-(Chloromethyl)-1,3-difluorobenzene (cas: 697-73-4) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 697-73-4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Schweizer, Ernst H. et al. published their research in Journal of Medicinal Chemistry in 1983 | CAS: 3438-16-2

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).SDS of cas: 3438-16-2

Sulfonyliminoimidazolidines. A new class of oral hypoglycemic agents. 1. 1-[[p-[2-(Acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines was written by Schweizer, Ernst H.;Maerki, Fritz;Lehmann, Claude;Dietrich, Henri. And the article was included in Journal of Medicinal Chemistry in 1983.SDS of cas: 3438-16-2 This article mentions the following:

A series of 1-[[p-[2-(acylamino)ethyl]phenyl]sulfonyl]-2-iminoimidazolidines were prepared from I (R = H). Compounds from this new class of oral hypoglycemic agents lowered blood glucose in normal and in streptozotocin-diabetic rats. Potent analogs were obtained by modification of the acyl residue. I (R = trans-MeCH:CHCO) was the most potent compound in the normal rat (20 times tolbutamide), and I (R = 5-methyl)-3-isoxazolylcarbonyl) displayed the highest potency in the diabetic rat (similar to phenformin). Structure-activity relationships were discussed. In the experiment, the researchers used many compounds, for example, 5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2SDS of cas: 3438-16-2).

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).SDS of cas: 3438-16-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Frazee, W. James et al. published their research in International Journal of Chemical Kinetics in 2019 | CAS: 620-19-9

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Formula: C8H9Cl

Temperature dependence of the reactions of Cl with toluene and the xylenes was written by Frazee, W. James;Roscoe, John M.. And the article was included in International Journal of Chemical Kinetics in 2019.Formula: C8H9Cl This article mentions the following:

The temperature dependence of the rate coefficients for the reactions of Cl with toluene and the xylenes was examined from 290 to 362 K. Chem. anal. was by gas chromatog. The relative rate method was used for the kinetic anal., and the relative rate coefficients were converted to absolute values using absolute rate coefficients for the reference reactions obtained from recent critical evaluations. Most of the measurements were made at a total pressure of approx. 100 kPa in argon. There was very little temperature dependence, and variation of the total pressure and the concentration of O2 had no effect. The values of the absolute rate coefficients were independent of the reference reaction used. The reaction of Cl with toluene was studied relative to the reactions of Cl with isobutane, ethane, propane, and n-butane. The results were virtually independent of temperature, giving a mean value of (5 ± 1) x 10-11 cm3 mol.-1 s-1 for the absolute rate coefficient at 95% confidence. The reactions of Cl with the xylenes were studied relative to the reactions of Cl with isobutane, ethane, and propane. The rate coefficients were independent of the xylene isomer and had a very small neg. dependence on temperature The mean value of the absolute rate coefficient at 298 K was (1.4 ± 0.3) x 10-10 cm3 mol.-1 s-1 at the 95% confidence level. The results are in satisfactory agreement with those in the literature, all of which were measured at fixed temperatures very close to 298 K. The kinetic results are discussed in relation to published descriptions of the dynamics of reactions of Cl and OH with organic compounds In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Formula: C8H9Cl).

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Formula: C8H9Cl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ghalehbandi, Shermineh sadat et al. published their research in Organic Preparations and Procedures International in 2021 | CAS: 620-19-9

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Quality Control of 1-(Chloromethyl)-3-methylbenzene

Microwave Assisted Oxidation of Benzyl Halides to Aldehydes and Ketones with 4-Hydroxypyridinium Nitrate Functionalized Silica Gel in Aqueous Media was written by Ghalehbandi, Shermineh sadat;Ghazanfari, Dadkhoda;Ahmadi, Sayed Ali;Sheikhhosseini, Enayatollah. And the article was included in Organic Preparations and Procedures International in 2021.Quality Control of 1-(Chloromethyl)-3-methylbenzene This article mentions the following:

An eco-friendly heterogeneous oxidant based on 4-hydroxypyridinium nitrate functionalized silica gel was prepared for the oxidation of benzyl halides to the corresponding carbonyl compounds R1C(O)R2 [R1 = Ph, 4-FC6H4, 3-MeOC6H4, etc.; R2 = H, Me, Ph]. The oxidant was a stable solid and could be prepared from the reaction of sodium 4-pyridinolate with an acidic activated silica gel which was then reacted with HNO3. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Quality Control of 1-(Chloromethyl)-3-methylbenzene).

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Quality Control of 1-(Chloromethyl)-3-methylbenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics