Category: chlorides-buliding-blocks

Chloride substituents modify the physical properties of organic compounds in several ways. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Recommanded Product: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Gillaizeau, Isabelle;Dondasse, Ismael;Nicolas, Cyril;Mimoun, Liliane;Sukach, Volodymyr;Meudal, Herve research published 《 Iridium-Catalyzed β-C(sp²)-H Borylation of Enamides – Access to 3,3-Dihalogeno-2-methoxypiperidines》, the research content is summarized as follows. An efficient catalytic preparation of synthetically useful new α,β-unsaturated β-borylated enamides was achieved under relatively mild conditions via a regioselective iridium-catalyzed C(sp²)-H dehydrogenative borylation of enamides with B₂pin₂. The method features broad substrate scope, good functional group tolerance and efficient scale-up. These C-3 borylated enamides can be advantageously exploited in cross-coupling reactions and converted into valuable 3,3-dihalogeno-2-methoxypiperidines in very short reaction times.

Recommanded Product: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Related Products of 104-86-9.

Goh, Jeffrey;Ong, Seng Kheong;Tan, Yan Sheng;Loh, Teck-Peng research published 《 Catalyst-free C-N bond formation under biocompatible reaction conditions》, the research content is summarized as follows. A C-N bond formation reaction under biocompatible conditions for the amination of allenic ketone compounds to access a diversity of β-keto enamines R¹C(O)HC=CMeNHR² [R¹ = Ph, cyclopentyl, 4-MeOC₆H₄, etc.; R² = Ph, cyclohexyl, Bn, etc.] was developed. This reaction was atom economical, green and highly regioselective and works well with many structurally important amines such as amino sugar and amino acid esters or peptides. A wide array of β-keto enamines R¹C(O)HC=CMeNHR² was obtained in modest to excellent yields with wide functional group tolerance using this protocol. A gram-scale synthesis of an anti-microbial agent was also realized using this strategy under green reaction conditions.

104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., Related Products of 104-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 349-88-2, formula is C6H4ClFO2S, Name is 4-Fluorobenzene-1-sulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Synthetic Route of 349-88-2.

Gong, Bozhen;Zhu, Haibo;Yang, Liu;Wang, Haifeng;Fan, Qiangwen;Xie, Zongbo;Le, Zhanggao research published 《 Base-promoted synthesis of diarylsulfones from sulfonyl hydrazines and diaryliodonium salts》, the research content is summarized as follows. An efficient and concise method for the synthesis of diaryl sulfones ArS(O)₂Ar¹ [Ar = Ph, 4-MeC₆H₄, 4-NCC₆H₄, etc.; Ar¹ = Ph, 4-FC₆H₄, 3-MeC₆H₄, etc.] via metal-free sulfonylation from sulfonyl hydrazines with sym. or unsym. diaryliodonium salts using n-PrOH as the solvent was developed with high selectivity. Using n-PrOH as the solvent, diaryl sulfones are formed even on a gram scale.

Synthetic Route of 349-88-2, 4-Fluorobenzenesulfonyl chloride is a useful research compound. Its molecular formula is C6H4ClFO2S and its molecular weight is 194.61 g/mol. The purity is usually 95%.

4-Fluorobenzenesulfonyl Chloride is found to be an excellent activating agent for the covalent attachment of biological substances to a variety of solid supports e.g. Sepharose beads. 4-Fluorobenzenesulfonyl Chloride is also used as a reagent for the studies of proteins by fluorine NMR.

4-Fluorobenzenesulfonyl chloride is a reactive chemical that has been shown to have a low safety profile in humans. It is used in the synthesis of replication inhibitors, which are potential anticancer drugs. It also has been shown to inhibit tumor metastasis and growth in mice by binding to the active site of DNA polymerase and inhibiting DNA replication. 4-Fluorobenzenesulfonyl chloride is stable in human liver cells and has been shown to be an effective macroinitiator for proton-coupled electron transfer reactions. This compound has been shown to induce locomotor activity and energy efficiency in rats, which may be due to its ability to increase the number of mitochondria per cell., 349-88-2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Gonzalez-Lainez, Miguel;Jimenez, M. Victoria;Azpiroz, Ramon;Passarelli, Vincenzo;Modrego, F. Javier;Perez-Torrente, Jesus J. research published 《 N-Methylation of Amines with Methanol Catalyzed by Iridium(I) Complexes Bearing an N,O-Functionalized NHC Ligand》, the research content is summarized as follows. A set of neutral [IrBr(L₂)(κC-^tBuImCH₂PyCH₂OMe)] and cationic [Ir(L₂)(κ²C,N-^tBuImCH₂PyCH₂OMe)]PF₆ (L₂ = cod, (CO)₂) Ir(I) compounds featuring a flexible lutidine-derived polydentate ligand having NHC and -OMe as donor functions were evaluated as catalyst precursors for the N-methylation of aniline using MeOH both as a reducing agent and a C1 source. The carbonyl complexes are somewhat more active than the related diene compounds with the neutral compound [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] being the more active. A range of aromatic primary amines, including heterocyclic amines, were selectively transformed into the corresponding N-methylamino derivatives using this catalyst at a low catalyst loading (0.1 mol %) and substoichiometric amounts of Cs₂CO₃ (half equiv) as a base, in MeOH at 423 K. For aliphatic primary amines, selective N,N-dimethylation was achieved under the same catalytic conditions. The unselective deprotonation of the methylene linkers in [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] affords two isomeric neutral complexes featuring a coordinated dearomatized pyridine core, which were converted into [Ir(OMe)(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] upon addition of MeOH. This compound undergoes thermal activation of a C-H bond of the tert-Bu group to give the cyclometalated Ir(I) complex [Ir(CO)₂{κ²C,C-(-CH₂Me₂C-ImCH₂PyCH₂OMe)}] featuring a bidentate C,C-coordinated NHC ligand. Mechanistic studies support a borrowing H mechanism proceeding through Ir(I) intermediates with the methoxo complex as the catalytic active species and the cyclometalated complex as the catalyst resting state. D labeling experiments demonstrated that both species are in equilibrium under catalytic conditions, which is consistent with the exhibited catalytic activity of the cyclometalated complex.

Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Related Products of 6334-18-5.

Govindaraju, Santhosh;Tabassum, Sumaiya research published 《 Sulphuric acid supported silica gel (H₂SO₄-SiO₂) as an efficient catalyst for one-pot multicomponent synthesis of pyrano[2,3-c]pyrazol-amines under ultrasonication》, the research content is summarized as follows. In this study, the catalytic potential of a novel heterogeneous catalyst-sulfuric acid supported on silica gel (H₂SO₄-SiO₂) has been assessed for the one-pot cyclo condensation reaction of aromatic aldehydes RCHO (R = 2-chlorophenyl, 2,4-dichlorophenyl, 2-hydroxy 5-bromophenyl, etc.), phenylacetonitriles 4-R¹-C₆H₄CH₂CN (R¹ = F, NO₂), Et acetoacetate and hydrazine to furnish poly functionalized pyrano[2,3-c]pyrazol-amine scaffolds I under ultrasonication. Notably, within the framework of green chem., this divergent and step-economic approach has many benefits such as (i) use of water as solvent in the reaction, (ii) creation of up to five bonds in one sequence, (iii) avail of US irradiation as an efficient source of energy, (iv) application of nontoxic and reusable catalyst. Besides these, simple workup procedure, low catalyst loadings, shorter reaction time, high functional group compatibility, readily accessible starting materials and excellent yields without column chromatog. render this protocol novel and greener towards the synthesis of poly functionalized pyrano[2,3-c]pyrazol-amines I.

Related Products of 6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Application In Synthesis of 104-86-9.

Granato, Alisson Silva;de Carvalho, Gustavo S. Goncalves;Fonseca, Carla G.;Adrio, Javier;Leitao, Alexandre A.;Amarante, Giovanni Wilson research published 《 On the mixed oxides-supported niobium catalyst towards benzylamine oxidation》, the research content is summarized as follows. A series of mixed oxides-supported niobium-based catalysts has been synthesized and applied towards oxidation reactions of benzylamine derivatives Under the optimized reaction conditions, the selectivity to oxime enhanced, leading to the main product with up to 72%. Moreover, even α-substituted benzylamines were well tolerated and led to oximes in good isolated yields. It is important to mention; four equivalent of the harmless and inexpensive hydrogen peroxide were employed as oxidizing agent. Mechanism hypothesis suggested that the reaction proceed to selective benzylamine oxidation into nitroso intermediate, following by formation of the corresponding oxime tautomer mediated by an unstable water produced by NbO_x supported catalyst. This consists the first mixed oxides-supported niobium-based catalyst for selective oxidation of benzylamines to oximes.

104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., Application In Synthesis of 104-86-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chloride substituents modify the physical properties of organic compounds in several ways. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Formula: C7H4Cl2O.

Enbaraj, E.;Dhineshkumar, E.;Jeyashri, K. R.;Logeshwari, G.;Devi, V. J. Ramya;Manikandan, H.;Seenivasan, M.;Rajathi, V.;Chakkaravarthy, J.;Govindaraju, R. research published 《 Novel synthesis of NE,N’E-4,4′-sulfonylbis(N-substituted-dichlorobenzylidene)anilines derivative their application biological and DFT studies》, the research content is summarized as follows. The synthesized compounds I (R¹ = H, Cl; R² = H; R³ = H, Cl; R⁴ = H, Cl; R⁵ = H, Cl) were evaluated for their in vitro activity against several microbes. Compound I exhibited potent antibacterial activity with the reference standard ciprofloxacin and fluconazol. In the ground-state, compounds I mol. geometries were determined using the DFT based on B3LYP/6-31G(d,p) and compared to the exptl. results. In addition, compounds I, MEP maps and mol. frontier orbitals were performed, and the results obtained were compatible with the electronic properties.

6334-18-5, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., Formula: C7H4Cl2O

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 6334-18-5, formula is C7H4Cl2O, Name is 2,3-Dichlorobenzaldehyde. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Formula: C7H4Cl2O.

Enbaraj, E.;Dhineshkumar, E.;Jeyashri, K. R.;Logeshwari, G.;Mohana, V.;Manikandan, H.;Rajathi, V.;Chakkaravarthy, J.;Govindaraju, R.;Seenivasan, M. research published 《 Novel synthesis, spectral characterisation and DFT calculation of (3,4-bis((E)-(substituted-dichlorobenzylidene)amino) phenyl) (phenyl) methanone derivatives》, the research content is summarized as follows. The organic compounds containing (3,4-bis((E)-(2,3-dichlorobenzylidene)amino)phenyl) (phenyl) methanone (1), (3,4-bis((E)-(2,6-dichlorobenzylidene)amino)phenyl)(phenyl) methanone (2) and (3,4-bis((E)-(3,4 dichlorobenzylidene)amino) phenyl)(phenyl) methanone (3) were synthesized in the current study. The synthesized methanone derivatives 1-3 are characterized by elemental anal., mass spectral studies, FT-IR, ¹H & ¹³C NMR. Due to the basis set to derive the optimized geometry, dipole moment, HOMO-LUMO energy, mol. electrostatic potential, Mulliken charge population, and first-order mol. hyperpolarization (β), theor. calculations were carried out using the DFT (B3LYP) strategy with 6-31G(d, p).

Formula: C7H4Cl2O, 2,3-Dichlorobenzaldehyde(2,3-DBA)is a useful research compound. Its molecular formula is C7H4Cl2O and its molecular weight is 175.01 g/mol. The purity is usually 95%.
2,3-DBA is an organic compound that is used as a synthetic intermediate in the preparation of other chemicals. It is prepared by reacting 2-chloroacetophenone with hydrochloric acid and sodium carbonate in a reaction vessel. The product can be purified through fractional distillation or crystallization. The optical properties of 2,3-DBA are determined by its dipole moment and the substituents attached to the methylene group. Molecular modeling studies have shown that felodipine can bind to 2,3-DBA through its active methylene group. The reaction products between sulfadiazine and 2,3-DBA are pyridinedicarboxylic acid and 3-chlorobenzaldehyde.
2,3-DBA is part of a group of Benzaldehyde (B119740) derivatives that exhibit activity against Mycobacterium tuberculosis, the bacteria responsible for causing tuberculosis in humans. 2,3-DBA is also used as a reagent to synthesize (E)-2-(2-arylhydrazinyl)quinoxalines, compounds that have potent anticancer activity., 6334-18-5.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 104-86-9, formula is C7H8ClN, Name is (4-Chlorophenyl)methanamine. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Related Products of 104-86-9.

Escudero, Julien;Mampuys, Pieter;Mensch, Carl;Bheeter, Charles B.;Vroemans, Robby;Orru, Romano V. A.;Harvey, Jeremy;Maes, Bert U. W. research published 《 Synthesis of Heterocycles via Aerobic Ni-Catalyzed Imidoylation of Aromatic 1,2-Bis-nucleophiles with Isocyanides》, the research content is summarized as follows. O-Phenylene N-substituted iminocarbonates I (R = cyclohexyl, i-Pr, t-Bu, etc.; R¹ = OMe, H; R² = H, OMe, NO₂, CH₂CH₂C=O(OMe), etc.) have been obtained by aerobic Ni-catalyzed reaction of readily available catechols 2-(OH)-3-R¹-5-R²C₆H₂OH and isocyanides RNC. The choice of oxidant and absence of base proved crucial to avoid competitive catechol oxidation into (semi)quinone, leading to degradation The developed protocol is generally applicable on other oxidation-sensitive aromatic 1,2-bis-nucleophiles, generating a variety of important bicyclic heterocycles from readily available building blocks, hitherto only accessible via aerobic noble metal catalysis. Exptl. studies suggest involvement of a Ni^II-catecholate complex, which has been supported by d. functional theory of the catalytic cycle. O-Phenylene N-substituted iminocarbonates demonstrated to be interesting platform mols. providing access to dialkyl N-substituted iminocarbonates RN=C(OR³)₂ (R = cyclohexyl, t-Bu, 4-MeOC₆H₄CH₂CH₂; R³ = n-Bu, Me, Bn, etc.), Di-Bu [2-(4-methoxyphenyl)ethyl]carbonodithioimidate, and N,N’-Dibutyl N”-[2-(4-methoxyphenyl)ethyl]guanidine via reaction with resp. alcs. R³OH, 1-butanethiol, and 1-butanamine. The catechol, which is concomitantly produced as a byproduct in these substitution reactions, can be recycled. When 4-propylcatechol, accessible from pine and clove tree feedstock, is applied, the leaving group is also biorenewable.

Related Products of 104-86-9, 4-Chlorobenzylamine is a useful research compound. Its molecular formula is C7H8ClN and its molecular weight is 141.6 g/mol. The purity is usually 95%.
4-Chlorobenzylamine is a reactant in the environmentally friendly synthesis of pyrroles.
4-Chlorobenzylamine is a chemical that is used as an intermediate in the synthesis of other compounds. It has low bioavailability, which may be due to its reactive site. The chemical can be characterized using nmr spectra and potent inhibitory activity. 4-Chlorobenzylamine has been found to react with nitrogen atoms, and this reaction is highly acidic. FT-IR spectroscopy can also be used to characterize this compound. Intermolecular hydrogen bonding and hydroxyl group are two of the major interactions of 4-chlorobenzylamine with other molecules. This chemical reacts with serine protease, glyoxal, and other substances in a manner that depends on the molecule’s structure., 104-86-9.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Faiges, Jorge;Borras, Carlota;Pastor, Isidro M.;Pamies, Oscar;Besora, Maria;Dieguez, Montserrat research published 《 Density Functional Theory-Inspired Design of Ir/P,S-Catalysts for Asymmetric Hydrogenation of Olefins》, the research content is summarized as follows. In silico-based optimization of Ir/P,S-catalysts for the asym. hydrogenation of unfunctionalized olefins using (E)-1-(but-2-en-2-yl)-4-methoxybenzene as a benchmark olefin has been carried out. DFT calculations revealed that the thioether group has a major role in directing the olefin coordination. This, together with the configuration of the biphenyl phosphite group, has an impact in maximizing the energy gap between the most stable transition states leading to opposite enantiomers. As a result, the optimized catalyst proved to be efficient in the hydrogenation of a range of alkenes with the same substitution pattern and olefin geometry as the benchmark olefin, regardless of the presence of functional groups with different coordination abilities (ee values up to 97%). Appealingly, further modifications at the thioether groups and at the biaryl phosphite moiety allowed the highly enantioselective hydrogenation of olefins with different substitution patterns (e.g., α,β-unsaturated lactones and lactams, 1,1′-disubstituted enol phosphinates, and cyclic β-enamides; ee values up to >99%).

Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics