Category: chlorides-buliding-blocks

Heat Capacity of α,ω-Bromochloroalkanes and α,ω-Dibromoalkanes: Their Dependence on the Hydrocarbon Chain Length and Temperature (285.15 to 355.15) K [Erratum to document cited in CA156:296087] was written by Goralski, Pawel;Tkaczyk, Mariola. And the article was included in Journal of Chemical & Engineering Data in 2012.Recommanded Product: 1-Bromo-6-chlorohexane The following contents are mentioned in the article:

On page 793, Table 4 and Figure 2 contained errors in the C_p data; the corrected table and figure are given. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Recommanded Product: 1-Bromo-6-chlorohexane).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: 1-Bromo-6-chlorohexane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development [Erratum to document cited in CA163:218209] was written by Shaw, Scott A.;Balasubramanian, Balu;Bonacorsi, Samuel;Caceres Cortes, Janet;Cao, Kevin;Chen, Bang-Chi;Dai, Jun;Decicco, Carl;Goswami, Animesh;Guo, Zhiwei;Hanson, Ronald;Humphreys, W. Griffith;Lam, Patrick Y. S.;Li, Wenying;Mathur, Arvind;Maxwell, Brad D.;Michaudel, Quentin;Peng, Li;Pudzianowski, Andrew;Qiu, Feng;Su, Shun;Sun, Dawn;Tymiak, Adrienne A.;Vokits, Benjamin P.;Wang, Bei;Wexler, Ruth;Wu, Dauh-Rurng;Zhang, Yingru;Zhao, Rulin;Baran, Phil S.. And the article was included in Journal of Organic Chemistry in 2015.Safety of (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate The following contents are mentioned in the article:

Other work on clopidogrel metabolite synthesis was omitted from the reference list; a corrected reference 13 is given. This study involved multiple reactions and reactants, such as (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0Safety of (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate).

(S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of acyclic alkanes by metal substitution with extension of the carbon framework was written by Kantchev, E. A. B.;Organ, M. G.. And the article was included in Science of Synthesis in 2009.COA of Formula: C6H12BrCl The following contents are mentioned in the article:

A review of methods to prepare acyclic alkanes by metal substitution with extension of the carbon framework. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3COA of Formula: C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).COA of Formula: C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of 4-amino-6-chloro-1,3,5-triazin-2(1H)-ones was written by Bakharev, V. V.;Gidaspov, A. A.;Parfenov, V. E.;Ul’yankina, I. V.;Zavodskaya, A. V.;Selezneva, E. V.;Suponitskii, K. Yu.;Sheremetev, A. B.. And the article was included in Russian Chemical Bulletin in 2012.Formula: C9H6Cl2N4 The following contents are mentioned in the article:

Conditions for selective substitution for one Cl in 2-(substituted amino)-4,6-dichloro-1,3,5-triazines with HO^– were elaborated. Spectra and calculation showed that the products formed are in the lactam form, i.e., have the structure of 4-chloro-6-(substituted amino)-1,3,5-triazin-2(1H)-ones. This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Formula: C9H6Cl2N4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Formula: C9H6Cl2N4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Asymmetric synthesis of δ-substituted-β-keto esters and β-substituted ketones via carboxyl-assisted site- and enantio-selective addition reactions was written by Zhu, Huiling;Liu, Peng;Liu, Hongxin;Ahmed, Ebrahim-Alkhalil M. A.;Hu, Xingen;Li, Juan;Xiao, Hong-Ping;Li, Xinhua;Jiang, Jun. And the article was included in Organic Chemistry Frontiers in 2022.Electric Literature of C6H9ClO3 The following contents are mentioned in the article:

Carboxyl-assisted site- and enantio-selective additions of polyfunctional nucleophiles to imines and carbonyls were developed, affording δ-substituted-β-keto esters and β-substituted ketones with good yields and enantioselectivities. Besides, short synthetic routes to bioactive mols. were also achieved. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Electric Literature of C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Electric Literature of C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Convenient one-step synthesis of quinoline-3,4-dicarboxylate derivatives was written by Ge, Youjin;Yu, Niefang. And the article was included in Synthetic Communications in 2021.Product Details of 638-07-3 The following contents are mentioned in the article:

Herein a practical and convenient procedure for the one-step synthesis of quinoline-3,4-dicarboxylate derivatives from isatins and β-keto esters in alcs. catalyzed by sulfuric acid was described. This novel protocol offers the advantages of high conversion rates, short reaction times, and easy handling. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Product Details of 638-07-3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 638-07-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Factors Determining the Effectiveness of Dyeing Fiber Materials Using Quaternary Ammonium Salts was written by Mikhailovskaya, A. P.. And the article was included in Fibre Chemistry in 2018.Related Products of 122-18-9 The following contents are mentioned in the article:

The results of studies of the intensification of dyeing of polyester, polypropylene and cotton fibers using quaternary ammonium salts are presented. For each type of fiber, salts of a certain chem. structure are recommended, and the technol. regime of effective dyeing of textile materials is optimized. This study involved multiple reactions and reactants, such as N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9Related Products of 122-18-9).

N-Benzyl-N,N-dimethylhexadecan-1-aminium chloride (cas: 122-18-9) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Related Products of 122-18-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and application of chiral triazine condensing reagents prepared from esters of amino acids was written by Kaminski, Zbigniew J.;Zajac, Krzysztof J.;Jastrzabek, Konrad. And the article was included in Acta Biochimica Polonica in 2001.Formula: C9H6Cl2N4 The following contents are mentioned in the article:

Treatment of cyanuric chloride with chiral amines or esters of chiral amino acids gave chiral 2,4-dichloro-6-alkylamino-1,3,5-triazines (2-5) in 49-69% yield, which were found useful as coupling reagents. Enantioselective activation and enantioselective aminolysis in the presence of 2-5 was observed This study involved multiple reactions and reactants, such as 4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4Formula: C9H6Cl2N4).

4,6-Dichloro-N-phenyl-1,3,5-triazin-2-amine (cas: 2272-40-4) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Formula: C9H6Cl2N4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Method of splitting key intermediate of clopidogrel was written by Xu, Han-qing. And the article was included in Guangzhou Huagong in 2014.Recommanded Product: 141109-14-0 The following contents are mentioned in the article:

The racemic 2-(2-chlorophenyl)glycine as the starting material, through esterification to give racemic 2-(2-chlorophenyl)glycine Me ester, resolved by (L)-(+)-tartrate, Bu ketone as solvent, (S)-(+)-2-(2-chlorophenyl)glycine Me ester was obtained, and the solvent recovery yield was more than 95%. This study involved multiple reactions and reactants, such as (S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0Recommanded Product: 141109-14-0).

(S)-Methyl 2-amino-2-(2-chlorophenyl)acetate (cas: 141109-14-0) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Recommanded Product: 141109-14-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Acid-catalyzed reaction of 1-(2,2-dimethoxyethyl)ureas with phenols as an effective approach to diarylethanes and dibenzoxanthenes was written by Smolobochkin, A. V.;Gazizov, A. S.;Voronina, J. K.;Rizbayeva, T. S.;Burilov, A. R.;Pudovik, M. A.. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2019.Formula: C6H5ClO2 The following contents are mentioned in the article:

A one-pot synthesis of urea-substituted diarylethanes and dibenzoxanthenes starting from 1-(2,2-dimethoxyethyl)ureas and phenols was developed. The approach used readily available reagents and catalysts, requires mild reaction conditions and provides the target compounds in good to high yields. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Formula: C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Formula: C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics