Category: chlorides-buliding-blocks

Arylsulfonic acid derivatives. XIV. Synthesis and antibacterial activity of new derivatives of 4-alkoxybenzylsulfonamides was written by Grigoryan, L. A.;Kaldrikyan, M. A.;Engoyan, A. P.;Paronikyan, R. V.. And the article was included in Armyanskii Khimicheskii Zhurnal in 1987.Electric Literature of C10H13ClO3S This article mentions the following:

p-ROC₆H₄SO₂Cl (I; R = C₁-C₄ n-alkyl, Me₂CHCH₂) reacted with R¹(CH₂)_nNH₂ (R¹ = Ph, p-MeOC₆H₄; n = 1, 2) in aqueous NaOH to give 15 corresponding p-ROC₆H₄SO₂NH(CH₂)_nR¹ (II) in 55-83% yield. II (same R; R¹ = Ph, n = 1, 2; R = Me, R¹ = p-MeOC₆H₄, n = 1) reacted with addnl. I (same R) or with p-R²C₆H₄CH₂Cl (R² = H, MeO) in dry DMF containing LiH to give 14 corresponding (p-ROC₆H₄SO₂)₂N(CH₂)_nR¹ (III) in 38-61% yield and 31-33% p-MeOC₆H₄CH₂N(CH₂C₆H₄R²–p)SO₂C₆H₄OEt-p (same R²), resp. III had antibacterial activity, but II did not. In the experiment, the researchers used many compounds, for example, 4-Butoxybenzene-1-sulfonyl chloride (cas: 1138-56-3Electric Literature of C10H13ClO3S).

4-Butoxybenzene-1-sulfonyl chloride (cas: 1138-56-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Electric Literature of C10H13ClO3S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

SkinEthic HCE Time-to-Toxicity on solids: A test method for distinguishing chemicals inducing serious eye damage, eye irritation and not requiring classification and labeling was written by Alepee, Nathalie;Leblanc, Virginie;Grandidier, Marie-Helene;Teluob, Severine;Viricel, Anaelle;Adriaens, Els;Michaut, Valerie. And the article was included in Toxicology In Vitro in 2021.Application of 101-20-2 This article mentions the following:

This study describes the development of a Time-to-Toxicity approach for solids (TTS) based on the SkinEthic HCE tissue construct, capable to distinguish chems. that do not require classification for serious eye damage/eye irritation (No Cat.) from chems. that require classification for eye irritation (Cat. 2), and serious eye damage (Cat. 1). Briefly, the time-to-toxicity of 69 solids was evaluated by exposing SkinEthic HCE tissue constructs to the test chem. for two different time periods (30-min, and 120-min). Based on the viability observed for the different exposure periods, a classification was assigned. The within laboratory reproducibility in terms of concordance in classifications (3 UN GHS categories), based on a set of 48 solids, was 93.7%. Furthermore, 73.6% Cat. 1 (N = 24), 55.6% Cat. 2 (N = 15) and 72.2% No Cat. (N = 30) were correctly identified with the SkinEthic HCE TTS test method. This study provides evidence that the SkinEthic HCE Time-to-Toxicity method (multiple exposure times) can distinguish Cat. 2 solids from Cat. 1 solids. This is an added value compared to the SkinEthic HCE EITS method (single exposure time) that can distinguish No Cat. chems. from chems. that do require classification and labeling for eye irritation/serious eye damage (Cat. 2/Cat. 1). In the experiment, the researchers used many compounds, for example, 1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2Application of 101-20-2).

1-(4-Chlorophenyl)-3-(3,4-dichlorophenyl)urea (cas: 101-20-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Application of 101-20-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis and SAR of 5-, 6-, 7- and 8-Aza Analogues of 3-Aryl-4-hydroxyquinolin-2(1H)-one as NMDA/Glycine Site Antagonists was written by Zhou, Z.-L.;Navratil, J. M.;Cai, S. X.;Whittemore, E. R.;Espitia, S. A.;Hawkinson, J. E.;Tran, M.;Woodward, R. M.;Weber, E.;Keana, J. F. W.. And the article was included in Bioorganic & Medicinal Chemistry in 2001.COA of Formula: C9H9ClO2 This article mentions the following:

A series of 5-, 6-, 7- and 8-aza analogs of 3-aryl-4-hydroxyquinolin-2(1H)-one was synthesized and assayed as NMDA/glycine receptor antagonists. The in vitro potency of these antagonists was determined by displacement of the glycine site radioligand [³H]5,7-dichlorokynurenic acid ([³H]DCKA) in rat brain cortical membranes. Selected compounds were also tested for functional antagonism using electrophysiol. assays in Xenopus oocytes expressing cloned NMDA receptor (NR) 1A/2C subunits. Among the 5-, 6-, 7-, and 8-aza-3-aryl-4-hydroxyquinoline-2(1H)-ones investigated, 5-aza-7-chloro-4-hydroxy-3-(3-phenoxyphenyl)quinolin-2-(1H)-one (I) is the most potent antagonist, having an IC₅₀ value of 110 nM in [³H]DCKA binding and a K_b of 11 nM in the electrophysiol. assay. Compound I is also an active anticonvulsant when administered systemically in the mouse maximum electroshock-induced seizure test (ED₅₀=2.3 mg/kg, IP). In the experiment, the researchers used many compounds, for example, 2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0COA of Formula: C9H9ClO2).

2-(3-Methoxyphenyl)acetyl chloride (cas: 6834-42-0) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C9H9ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Intermolecular Reductive Heck Reaction of Unactivated Aliphatic Alkenes with Organohalides was written by Zheng, Kewang;Xiao, Guanlin;Guo, Tao;Ding, Yalan;Wang, Chengdong;Loh, Teck-Peng;Wu, Xiaojin. And the article was included in Organic Letters in 2020.Application In Synthesis of 5-Bromo-2-chloro-m-xylene This article mentions the following:

A general intermol. reductive Heck reaction of organohalides with both terminal and internal unactivated aliphatic alkenes has been first realized in high yield with complete anti-Markovnikov selectivity. The challenging vinyl bromides, aryl chlorides, and polysubstituted internal alkenes were first applied. More than 100 remote carbofunctionalized alkyl carboxylic acid derivatives were rapidly synthesized from easily accessible starting materials. The synthesis of drug mols. has further demonstrated the wide synthetic utility of this scalable strategy. Preliminary mechanistic studies are consistent with the proposed catalytic cycle. In the experiment, the researchers used many compounds, for example, 5-Bromo-2-chloro-m-xylene (cas: 206559-40-2Application In Synthesis of 5-Bromo-2-chloro-m-xylene).

5-Bromo-2-chloro-m-xylene (cas: 206559-40-2) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Application In Synthesis of 5-Bromo-2-chloro-m-xylene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Some interconversion reactions of organolithium compounds was written by Gilman, Henry;Langham, Wright;Moore, Fred W.. And the article was included in Journal of the American Chemical Society in 1940.Product Details of 3438-16-2 This article mentions the following:

Details are given of 28 reactions of halo derivatives of C₆H₆, PhMe and PhOMe with BuLi in ether or petr. ether (I) with carbonation by pouring upon solid CO₂ to give acids. PhBr in ether (0.25-0.5 h.) gives 46-51% of BzOH; reaction of 0.05 mol. mixture for 1, 5, 20 and 24 h. gives 36, 15, trace and 3.4% BzOH; in I (24 h.) the yield of BzOH is 44.8%. PhI (0.25 h.) gives 49-51% BzOH; after 0.5 and 1 h. the yields are 41 and 27%; in 5 and 20 h. the yields are 13% and a trace. m-ClC₆H₄I gives 41.5% of m-ClC₆H₄CO₂H. p-ClC₆H₄Br gives 90% of p-ClC₆H₄CO₂H. p-C₆H₄B₂ in ether gives 54% p-BrC₆H₄CO₂H; in I (24 h.), 88.7% of p-C₆H₄(CO₂H)₂; in ether (5.5 h.) there was formed 67% of p-BrC₆H₄CO₂H and 33% of p-C₆H₄(CO₂H)₂. 1,3,5-C₆H₃Br₃ gives 71% of 3,5-Br₂C₆H₃CO₂H. o-BrC₆H₄Me in ether (0.25 h.) gives 83.8% and in I (20 h.) 41.7% o-MeC₆H₄CO₂H. m-BrC₆H₄Me in ether (0.25 h.) gives 65.4% and in I (20 h.) 46.1% of m-MeC₆H₄CO₂H. p-BrC₆H₄Me in ether gives 51% and in I 86.2% of p-MeC₆H₄CO₂H. p-IC₆H₄Me in ether yields 72% p-MeC₆H₄CO₂H. o- and p-BrC₆H₄OMe give 72.3 and 52% of o- and p-MeOC₆H₄CO₂H; p-IC₆H₄OMe gives 78% of p-MeOC₆H₄CO₂H. 2,5-Br₂C₆H₃Me (II) and BuLi (0.025 mol each) (15 min.) give 63% of a mixture containing 29% of 3,4-MeBrC₆H₃CO₂H (III), 20.5% of the 2,4-isomer (?) (IV) and 19% of II; with 0.025 mol of II and 0.03 mol BuLi (2 min.) there results 36.1% III and 22.3% IV; in I 0.015 mol II and 0.033 mol BuLi after 20 h. give 12.4% of III and 51.8% of 3-MeC₆H₃-(CO₂H)₂-1,4 (V); 0.01 mol II and 0.04 mol BuLi give 64.4% of V. 3-Bromoacenaphthene gives 55-62% of 3-acenaphthoic acid. (4-BrC₆H₄)₂ in 1 experiment gave 65% p-BrC₆H₄C₆H₄CO₂H (VI); in a 2nd experiment there was formed 67% of VI and 30% of (p-HO₂CC₆H₄)₂ (VII); in I the yield is 13% VI and 60.6% VII; in an experiment in which the I was distilled off during 10 h. the yield of VII was 91%. PhCH:CHBr and BuLi, heated in I for 20 h., give 23% of trans-PhCH:CHCO₂H; after 1 h., the yield is 19%; in ether there is formed 42.5% of PhCCCO₂H. p-ClC₆H₄OMe in ether gives 56% of 5,2-Cl(MeO)C₆H₃CO₂H, m. 97.5° (previously reported 80-2°); after 24 h. at 18-20° the yield was 74%. p-FC₆H₄OMe gives 10-13% of 5,2-F(MeO)C₆H₃CO₂H. 2,4,6-Br₃C₆H₂OMe in ether gives 16-19% of 3,5,2-Br₂(MeO)C₆H₂CO₂H; in I there results 75-88% of 5,2,1,3-Br(MeO)C₆H₂(CO₂H)₂. p-BrC₆H₄OPh gives 70% of p-PhOC₆H₄CO₂H. (4-BrC₆H₄)₂O yields 56.3% of 4-(4-BrC₆H₄O)C₆H₄CO₂H. Procedures are given for the conversion of small blocks of Li to the generally more effective smaller particles. An apparatus is illustrated for filtration of organolithium solutions Advantages of the use of I as a solvent in this type of reaction are listed. The following generalizations are drawn from this work: Metalation of aryl ethers involves H or hydrogens on C ortho to the ether linkage. All types of aryl bromides and iodides undergo the halogen-metal interconversion reaction. Iodides react more readily than the bromides, and chlorides and fluorides are essentially not affected. There are 2 chief competitive reactions: halogen-metal interconversions (RX + R’Li → RLi + R’X) and couplings (RX + R’Li → RLi + R’X → RR’ + LiX). The coupling reaction is not only the slower reaction but often also follows the interconversion reaction. As the reaction time is extended, the coupling reaction predominates and eventuates in the essential disappearance of RLi compound In the experiment, the researchers used many compounds, for example, 5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2Product Details of 3438-16-2).

5-Chloro-2-methoxybenzoic acid (cas: 3438-16-2) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Product Details of 3438-16-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Identification and initial evaluation of 4-N-aryl-[1,4]diazepane ureas as potent CXCR3 antagonists was written by Cole, Andrew G.;Stroke, Ilana L.;Brescia, Marc-Raleigh;Simhadri, Srilatha;Zhang, Joan J.;Hussain, Zahid;Snider, Michael;Haskell, Christopher;Ribeiro, Sofia;Appell, Kenneth C.;Henderson, Ian;Webb, Maria L.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2006.HPLC of Formula: 1711-11-1 This article mentions the following:

The identification and evaluation of aryl-[1,4]diazepane ureas as functional antagonists of the chemokine receptor CXCR3 are described. Specific examples exhibit IC₅₀ values of ∼60 nM in a calcium mobilization functional assay, and dose-dependently inhibit CXCR3 functional response to CXCL11 (interferon-inducible T-cell α chemoattractant/I-TAC) as measured by T-cell chemotaxis, with a potency of approx. 100 nM. In the experiment, the researchers used many compounds, for example, 3-Cyanobenzoyl chloride (cas: 1711-11-1HPLC of Formula: 1711-11-1).

3-Cyanobenzoyl chloride (cas: 1711-11-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.HPLC of Formula: 1711-11-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tailored design of highly permeable polyamide-based nanofiltration membrane via a complex-dissociation regulated interfacial polymerization was written by Hao, Yufan;Yang, Na;Zhang, Longfei;Fang, Yao;Sun, Yongli;Jiang, Bin;Zhang, Luhong. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2023.Related Products of 4422-95-1 This article mentions the following:

Nanofiltration (NF) that can sep. neutral/charged solutes is considered as a key industrial technol. in water softening and wastewater treatment. However, com. polyamide (PA) NF membranes, with undesirable surface properties and excessive mass transfer resistance, seriously restrict the permeability and are easily attached by pollutants. In this study, a novel CDRIP strategy was proposed to prepare highly permeable polyamide-based NF membranes, in which tannic acid (TA)/Ca(II) complex was in situ formed on substrate surface and then dissociated by sodium citrate (SC) after interfacial polymerization Interestingly, SC can not only adjust surface properties of PA, such as hydrophilicity and surface charge, but also form water-soluble SC/Ca(II) complexes for constructing addnl. transport channels within the separation layer to reduce mass transfer resistance. After the dissociation of TA/Ca(II) complex, TA remained on the membrane surface to further regulate the surface properties of separation layer. The results showed that the PA/TA/Ca(II)-SC NF membrane maintained a high Na₂SO₄ rejection (98.5%) and a remarkable water permeability of 31.7 L.m^-2.h^-1.bar^-1. The prepared NF membrane exhibits favorable operation stability and anti-fouling ability. Therefore, by employing the CDRIP method, the permeability of NF membrane can be further improved almost without sacrificing the rejection of Na₂SO₄, which provides a green and efficient strategy for the fabrication of high-performance PA-based NF membranes. In the experiment, the researchers used many compounds, for example, Trimesoylchloride (cas: 4422-95-1Related Products of 4422-95-1).

Trimesoylchloride (cas: 4422-95-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Related Products of 4422-95-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Novel penta-1,4-diene-3-one derivatives containing quinazoline and oxime ether fragments: Design, synthesis and bioactivity was written by Su, Shijun;Chen, Mei;Li, Qin;Wang, Yihui;Chen, Shuai;Sun, Nan;Xie, Chengwei;Huai, Ziyou;Huang, Yinjiu;Xue, Wei. And the article was included in Bioorganic & Medicinal Chemistry in 2021.Computed Properties of C8H9Cl This article mentions the following:

A series of novel penta-1,4-diene-3-one derivatives I [R = H, [(2,4-dichlorophenyl)methyl]oxidanyl, [(2-chlorophenyl)methyl]oxidanyl, [(4-chlorophenyl)methyl]oxidanyl, [(2-fluorophenyl)methyl]oxidanyl; R¹ = thiophen-2-yl, pyridin-2-yl; R² = H, [(2-fluorophenyl)methyl]oxidanyl, [(2,4-dichlorophenyl)methyl]oxidanyl, [(3-methylphenyl)methyl]oxidanyl, etc.; R³ = H, 6-Cl, 8-Me] containing quinazoline and oxime ether moieties were designed and synthesized. Their anticancer activities were evaluated by MTT assay, and the results showed that most compounds exhibited extremely inhibitory effects against hepatoma SMMC-7721 cells. In particular, compounds I [R = R³ = H; R¹ = pyridin-2-yl; R² = [(3-methylphenyl)methyl]oxidanyl] (II) and I [R = H; R¹ = pyridin-2-yl; R² = [(4-chlorophenyl)methyl]oxidanyl; R³ = 6-Cl] (III) displayed the more potent inhibitory activity with IC₅₀ values of 0.64 and 0.63μM, which were better than that of gemcitabine (1.40μM). Further mechanism studies indicated that compounds II, III, I [R = [(2,4-dichlorophenyl)methyl]oxidanyl; R¹ = pyridin-2-yl; R² = R³ = H] and I [R = [(2,4-dichlorophenyl)methyl]oxidanyl; R¹ = pyridin-2-yl; R² = H; R³ = 6-Cl] could control the migration of SMMC-7721 cells effectively, and inhibit the proliferation of cancer cells by inhibiting the DNA replication. Western-blot results showed that compounds II and III induced irreversible apoptosis of SMMC-7721 cells by regulating the expression level of apoptose-related proteins. Those studies demonstrated that the penta-1,4-diene-3-one derivatives I containing quinazoline and oxime ether fragments merited further research as potential anticancer agents. In the experiment, the researchers used many compounds, for example, 1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9Computed Properties of C8H9Cl).

1-(Chloromethyl)-3-methylbenzene (cas: 620-19-9) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Computed Properties of C8H9Cl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Conjugation of two functional groups through an unsaturated system was written by Exner, Otto;Bohm, Stanislav. And the article was included in Journal of Physical Organic Chemistry in 2005.Application In Synthesis of (E)-4-Chlorobut-2-enoic acid This article mentions the following:

Energies of 51 1-(E),4-(E)-disubstituted 1,3-butadienes (1), 36 1,4-disubstituted benzenes (2) and 36 (E)-1,2-disubstituted ethenes (3) with dipolar substituents were calculated at the B3LYP/6-311 + G(d,p) level and evaluated in terms of isodesmic reactions expressing the interaction of substituents through the conjugated system. The energy of interaction reaches up to 40 kJ mol^-1, it is roughly similar in the three series and most regular in the series 1. While its correlation within the framework of dual substituent parameter anal. lacks phys. meaning, it is possible to sep. the conjugative (resonance) component by subtracting the inductive component with reference to 1,4-disubstituted bicyclo[2.2.2]octanes 4. The conjugative interaction is strongly stabilizing for the combination acceptor-donor and destabilizing for two donors; in these cases it is parallel to changes of geometry as they are predicted by the common resonance formulas. Interaction of two acceptors is weak; in addition, there are groups that cannot be classified either as donors or as acceptors. Therefore, one can construct a scale of the resonance ability of donors in conjugation with an acceptor and vice versa, but it is not possible to express the interaction of two donors or of two acceptors on a unified scale for all substituents. The resonance description is certainly appropriate for the typical examples (interaction of NO₂ and NH₂) but should not be generalized to all possible structures. In the experiment, the researchers used many compounds, for example, (E)-4-Chlorobut-2-enoic acid (cas: 26340-58-9Application In Synthesis of (E)-4-Chlorobut-2-enoic acid).

(E)-4-Chlorobut-2-enoic acid (cas: 26340-58-9) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Application In Synthesis of (E)-4-Chlorobut-2-enoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The study of the ultraviolet absorption of ortho-substituted anilines. II. N-Substituted ortho-halogenated anilines was written by Grammaticakis, P.. And the article was included in Bulletin de la Societe Chimique de France in 1949.Formula: C8H10ClN This article mentions the following:

The qual. relations between the spectra of the N-derivatives of o-toluidine and mesidine are generally retained when the Me group is replaced by Cl or Br. Br causes very slight, if any, shift toward the visible as compared with Cl. Spectra are reported of: o-ClC₆H₄NH₂ (I); 2,4,6-Cl₃C₆H₂NH₂ (II); 2,4,6-Br₃C₆H₂NH₂ (III); the N-mono-Me and N,N-di-Me derivatives of I, II, and III; the N-Ac, N-Bz, and N-formyl derivatives of I, II, and III and their N-mono-Me derivatives; the N,N-di-Ac derivatives of II and III; the N-cyclohexylidene derivatives of I and II; the N-benzylidene derivatives of I, II, and III; the N-phenylcarbamyl derivatives of I, II, and III and their N-mono-Me derivatives; the N-PhSO₂ derivative of I; the N-phenylcarbamyl derivative of mesidine and its mono-Bu derivative; the N-carbamyl derivatives of I and o-toluidine and o-acetotoluide. In the experiment, the researchers used many compounds, for example, 2-Chloro-N,N-dimethylaniline (cas: 698-01-1Formula: C8H10ClN).

2-Chloro-N,N-dimethylaniline (cas: 698-01-1) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Formula: C8H10ClN

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics