Category: chlorides-buliding-blocks

Shankar, Ravi published the artcileCatalytic oxidation of diorganosilanes to 1,1,3,3-tetraorganodisiloxanes with gold nanoparticle assembly at the water-chloroform interface, Related Products of chlorides-buliding-blocks, the publication is New Journal of Chemistry (2019), 43(2), 813-819, database is CAplus.

The formation of the spherical self-assembly of gold nanoparticles (AuNPs) of 200 ± 20 nm size at the water-chloroform interface is achieved by employing the cyclotetrasiloxane [RSCH₂CH₂SiMeO]₄ (R = CH₂CH₂OH) as the stabilizing ligand. The interfacially stabilized AuNPs act as a versatile catalyst for selective hydrolytic oxidation of only one of the Si-H bonds in secondary organosilanes, RR¹SiH₂ (R, R¹ = alkyl, aryl, and sila-alkyl), to afford the high yield synthesis of 1,1,3,3-tetraorganodisiloxanes, (HRR¹Si)₂O. The study unravels for the first time the role of the photothermal effect arising from the excitation of the surface plasmon resonance of the AuNPs under visible light irradiation in enhancing the catalytic activity at ambient temperature

New Journal of Chemistry published new progress about 14799-93-0. 14799-93-0 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(methyl)(octyl)silane, and the molecular formula is C8H6ClN, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shankar, Ravi published the artcileCatalytic oxidation of diorganosilanes to 1,1,3,3-tetraorganodisiloxanes with gold nanoparticle assembly at the water-chloroform interface, Recommanded Product: Dichloro(hexyl)(methyl)silane, the publication is New Journal of Chemistry (2019), 43(2), 813-819, database is CAplus.

The formation of the spherical self-assembly of gold nanoparticles (AuNPs) of 200 ± 20 nm size at the water-chloroform interface is achieved by employing the cyclotetrasiloxane [RSCH₂CH₂SiMeO]₄ (R = CH₂CH₂OH) as the stabilizing ligand. The interfacially stabilized AuNPs act as a versatile catalyst for selective hydrolytic oxidation of only one of the Si-H bonds in secondary organosilanes, RR¹SiH₂ (R, R¹ = alkyl, aryl, and sila-alkyl), to afford the high yield synthesis of 1,1,3,3-tetraorganodisiloxanes, (HRR¹Si)₂O. The study unravels for the first time the role of the photothermal effect arising from the excitation of the surface plasmon resonance of the AuNPs under visible light irradiation in enhancing the catalytic activity at ambient temperature

New Journal of Chemistry published new progress about 14799-94-1. 14799-94-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Dichloro(hexyl)(methyl)silane, and the molecular formula is C14H31NO2, Recommanded Product: Dichloro(hexyl)(methyl)silane.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Singh, Kartikey published the artcileMetal- and Phenol-Free Synthesis of Biaryl Ethers: Access to Dibenzobistriazolo-1,4,7-oxadiazonines and Vancomycin-Like Glyco-Macrocycles as Antibacterial Agents, COA of Formula: C6H3ClFNO2, the publication is Journal of Organic Chemistry (2018), 83(24), 14882-14893, database is CAplus and MEDLINE.

An efficient synthesis of biaryl ethers, from electron-deficient aryl halides using NaH/DMSO under metal- and phenol-free conditions, has been achieved to access dibenzo-bistriazolo-1,4,7-oxadiazonines and vancomycin-like glyco-macrocycles. A 44-membered glyco-macrocycle showed promising activity against vancomycin-resistant Staphylococcus aureus (VRSA).

Journal of Organic Chemistry published new progress about 350-30-1. 350-30-1 belongs to chlorides-buliding-blocks, auxiliary class Fluoride,Chloride,Nitro Compound,Benzene, name is 3-Chloro-4-fluoronitrobenzene, and the molecular formula is C6H9N3O2S, COA of Formula: C6H3ClFNO2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Singh, Karan published the artcileSynthesis, characterization and antimicrobial study of some novel fluorine based 2-aminothiazoles, Synthetic Route of 3696-23-9, the publication is International Journal of Pharmacy and Pharmaceutical Sciences (2014), 6(10), 429-433, 5 pp., database is CAplus.

The synthesis of some novel fluorine based 2-aminothiazoles I (R = 4-Cl, 4-CH₃, 4-NO₂, etc.; R¹ = 2,4-F₂C₆H₃, 3-O₂NC₆H₄, 4-H₃COC₆H₄, etc.), II (R² = Cl, CH₃, OCH₃) have been described by using hypervalent iodine [I(III)] mediated approach. The synthesized compounds I and II were screened for their anti-microbial activity. The results revealed that compounds I (R = 4-OCH₃, R¹ = 2,4-F₂C₆H₃; R = 2,4-Cl₂, R¹ = 2,4-F₂C₆H₃; R² = Cl; R² = CH₃; R² = OCH₃; R = 2,4-F₂, R¹ = 3-O₂NC₆H₄; R = 2,4-F₂, R² = C₆H₅) showed moderate to good antibacterial activity as compared with the standard drug chloramphenicol.

International Journal of Pharmacy and Pharmaceutical Sciences published new progress about 3696-23-9. 3696-23-9 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Thiourea,Amine,Benzene,Amide, name is 1-(4-Chlorophenyl)thiourea, and the molecular formula is C7H8BFO2, Synthetic Route of 3696-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Nadir, Upender K. published the artcileReaction of dimethyloxosulfonium methylide with oxaziridines – transformation to azetidines, Computed Properties of 5034-06-0, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (1989), 28B(8), 685-6, database is CAplus.

Reaction of N-arylsufonyloxaziridines I (R = SO₂C₆H₄H₄Me-4, SO₂Ph) with Me₂S(O):CH₂ yields azetidines whereas reaction with I (R = Me₃C) leads to the corresponding azomethine PhCH:NCMe₃.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 5034-06-0. 5034-06-0 belongs to chlorides-buliding-blocks, auxiliary class Salt,Aliphatic hydrocarbon chain, name is trimethyloxosulphonium chloride, and the molecular formula is C3H9ClOS, Computed Properties of 5034-06-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Gupta, Atul published the artcileEvaluation of in-vivo anti-implantation and in-vitro anti-proliferative activities of substituted 3-phenyl-4-phenylvinyl benzopyranone derivatives, Safety of 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, the publication is Letters in Drug Design & Discovery (2009), 6(1), 46-50, database is CAplus.

A series of substituted 3-phenyl-4-phenylvinyl benzopyranone derivatives (11a-e) was evaluated for their anti-implantation activity in mature female Sprague-Dawley rat model. Compounds were further evaluated for anti-proliferative activity in human adenocarcinoma breast cancer cell line (MCF-7 cancer cell line). The tested compounds showed significant anti-proliferative activity with moderate anti-implantation activity. The inhibitory concentration (IC₅₀) values of most active compounds 11 (c-e) are 8.43 μM, 7.97 μM and 7.91 μM resp. and comparable to that of tamoxifen (5.10 μM), a well known antiestrogen used for treatment of breast cancer.

Letters in Drug Design & Discovery published new progress about 4584-49-0. 4584-49-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Salt,Amine,Aliphatic hydrocarbon chain, name is 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride, and the molecular formula is C5H13Cl2N, Safety of 2-Chloro-N,N-dimethylpropan-1-amine hydrochloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Laha, Joydev K. published the artcileDesign, Sustainable Synthesis, and Programmed Reactions of Templated N-Heteroaryl-Fused Vinyl Sultams, Recommanded Product: ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, the publication is Journal of Organic Chemistry (2017), 82(18), 9350-9359, database is CAplus and MEDLINE.

A de novo design and synthesis of N-heteroaryl-fused vinyl sultams as templates for programming chem. reactions on vinyl sultam periphery or (hetero)aryl ring is described. The key features include rational designing and sustainable synthesis of the template, customized reactions of vinyl sultams at C=C bond or involving N-S bond cleavage, and reactions on the periphery of the heteroaryl ring for late-stage diversification. The simple, easy access to the template coupled with opportunities for the synthesis of diversely functionalized heterocyles from a single template constitutes a rare study in contemporary organic synthesis.

Journal of Organic Chemistry published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C10H15ClO3S, Recommanded Product: ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Herranz, Eugenio published the artcileOsmium-catalyzed vicinal hydroxyamination of olefins by chloramine-T: cis-2-(p-toluenesulfonamido)cyclohexanol and 2-methyl-3-(p-toluenesulfonamido)-2-pentanol. [Benzenesulfonamide, N-(2-hydroxycyclohexyl)-4-methyl-, cis-], HPLC of Formula: 7080-50-4, the publication is Organic Syntheses (1983), 85-93, database is CAplus.

Addition of p-MeC₆H₄SO₂NClNa (I) to Me₂C:CHEt in the presence of OsO₄ gave Me₂C(OH)CH(NHSO₂C₆H₄Me-p)Et. Similarly, addition of I to cyclohexene gave 75-81.2% II.

Organic Syntheses published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, HPLC of Formula: 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Norris, Peter published the artcileDevelopment of reactions of 6- and 5-substituted 1,3-dimethyluracils with dimethylsulfoxonium methylide, Application In Synthesis of 5034-06-0, the publication is Journal of Organic Chemistry (1999), 64(20), 7290-7298, database is CAplus.

6-Chloro-1,3-dimethyluracil reacts with dimethylsulfoxonium methylide, MeS(:O):CH₂, to give sulfoxonium ylide I in 51% yield. The structure of I was established spectroscopically and by its reactions with various electrophiles and electron-deficient olefins. Thus, I is converted by HCl to a sulfoxonium chloride which then yields 6-(chloromethyl)-1,3-dimethyluracil (II) by heating in MeCN. I undergoes deuterium exchange at the 5-position, at its methine carbon, and into its Me groups attached to sulfur. Reaction of I with BzCl gives the highly substituted ylide III or the nucleophilic substitution products II and (α-chlorophenacyl)uracil IV, depending on reaction conditions. Treatment of I with electron-deficient olefins yields 6-cyclopropyluracils, e.g. V. Many of the cyclopropyluracils were converted to trans-1-(1,3-dimethyluracilyl)-2-vinylcyclopropanes and cycloheptenyluracils. Reaction 5-(phenylsulfinyl)-1,3-dimethyluracil with MeS(:O):CH₂ yields cyclothymine VI, whereas reaction of 5-phenylseleninyl-1,3-dimethyluracil with MeS(:O):CH₂ gave I as the major product.

Journal of Organic Chemistry published new progress about 5034-06-0. 5034-06-0 belongs to chlorides-buliding-blocks, auxiliary class Salt,Aliphatic hydrocarbon chain, name is trimethyloxosulphonium chloride, and the molecular formula is C3H9ClOS, Application In Synthesis of 5034-06-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Boryak, O. A. published the artcileBinding of two cationic compounds with graphene oxide: comparative analysis and observation of synergetic effect, Synthetic Route of 38146-42-8, the publication is Functional Materials (2021), 28(3), 450-462, database is CAplus.

The present paper reports on the results of the joint interaction of two organic cationic compounds of different structure and nature, namely bisquaternary ammonium decamethoxinum (Dec) with flexible dication and methylene blue (MB) with heterocyclic planar cation, with graphene oxide (GO) in aqueous dispersion. The qual. differences in the 3D structures of GO modified in binary (GO + Dec), (GO + MB) and ternary (GO + Dec + MB) systems were observed and described on the basis of the UV-vis spectral anal. of the systems. On mixing the components of the binary (GO + Dec) system, a rather rapid gelation of GO dispersion was observed The appearance of binary (GO + MB) system showed dependence on GO to MB ratio: at low GO content, MB-induced coagulation of GO to tiny bluish flakes took place followed by their sedimentation with time while at high GO content, the GO complexes with MB preserved solubility in water. The result of the joint addition of both Dec and MB to GO dispersion differed qual. from the above results of action of individual components. On creation of the (GO + Dec + MB) ternary system rapid flocculation of all components of the system was observed resulting in the formation of dark residue surfacing over the purified decolorized liquid UV-vis spectra of the liquid phase showed suppression of the lines of all components or their complexes practically to the baseline. The compression of (GO + Dec + MB) composite to flocs is explained by the matching of the size of MB cation to that of Dec dication linker, which provides tight filling of the gaps between GO sheets. The observed flocculation effect in the (GO + Dec + MB) system may be of practical interest in the development of nanocomposite and sorption materials. Information on the features of GO interactions with organic cations differing in structure may be useful for advances in drug delivery problem.

Functional Materials published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Synthetic Route of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics