Category: 50-84-0

An article Predicting Aqueous Adsorption of Organic Compounds onto Biochars, Carbon Nanotubes, Granular Activated Carbons, and Resins with Machine Learning WOS:000538420500058 published article about MULTIPLE LINEAR-REGRESSION; WATER SORPTION COEFFICIENTS; PROPERTY RELATIONSHIP QSPR; FUNCTION NEURAL-NETWORK; SINGLE-WALLED CARBON; POLANYI-BASED MODELS; AROMATIC-COMPOUNDS; ENERGY RELATIONSHIP; PHENOLIC-COMPOUNDS; CONTAMINANTS in [Zhang, Kai; Zhong, Shifa; Zhang, Huichun] Case Western Reserve Univ, Dept Civil & Environm Engn, Cleveland, OH 44106 USA in 2020, Cited 79. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0. Formula: C7H4Cl2O2

Predictive models are useful tools for aqueous adsorption research; existing models such as multilinear regression (MLR), however, can only predict adsorption under specific equilibrium concentrations or for certain adsorption isotherm models. Also, few studies have discussed data processing beyond applying different modeling algorithms to improve the prediction accuracy. In this research, we employed a cosine similarity approach that focused on mining the available data before developing models; this approach can mine the most relevant data concerning the prediction target to build models and was found to considerably improve the prediction accuracy. We then built a machine-learning modeling process based on neural networks (NN), a group-selection data-splitting strategy for grouped adsorption data for adsorbent-adsorbate pairs under different equilibrium concentrations, and polyparameter linear free energy relationships (pp-LFERs) for aqueous adsorption of 165 organic compounds onto 50 biochars, 34 carbon nanotubes, 35 GACs, and 30 polymeric resins. The final NN-LFER models were successfully applied to various equilibrium concentrations regardless of the adsorption isotherm models and showed less prediction deviations than the published models with the root-mean-square errors 0.23-0.31 versus 0.23-0.97 log unit, and the predictions were improved by adding two key descriptors (BET surface area and pore volume) for the adsorbents. Finally, interpreting the NN-LFER models based on the Shapley values suggested that not considering equilibrium concentration and properties of the adsorbents in the existing MLR models is a possible reason for their higher prediction deviations.

Formula: C7H4Cl2O2. Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about THERMAL-DECOMPOSITION KINETICS; ORGANIC FRAMEWORKS; CRYSTAL-STRUCTURE; BUILDING UNITS; COMPLEXES; IONS; ACID; 3D; EUROPIUM(III); TERBIUM(III), Saw an article supported by the Education Baureau of Liaoning Province [LQ2017011]; Natural Science Foundation of Liaoning ProvinceNatural Science Foundation of Liaoning Province [2019-ZD-0495]. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Zhang, JW; Wang, CR; Liu, WH; Xu, S; Liu, BQ. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid. COA of Formula: C7H4Cl2O2

Ln(NO3)(3)center dot nH(2)O reacted with 2,4-dichlorobenzoic acid (2,4-HDCB) and NaOH under solvothermal conditions of water and ethanol to yield four lanthanide-organic coordination polymers (CPs) [Eu(2,4-DCB)(3)(CH3CH2OH)(2)] (1) and [Ln(2,4-DCB)(3)(H2O)] [Ln = Gd (2), Tb (3), Dy (4)]. The second ligand 4,4′-bipyridine (4,4′-bpy) was introduced into the above reaction systems to provide four new lanthanide-organic CPs [Ln(2)(2,4-DCB)(6)(4,4′-bpy)(H2O)(2)] [Ln = Eu (5), Gd (6), Tb (7), Dy (8)]. Single-crystal and powder X-ray diffraction analyses reveal that CPs 1 and 2 possess similar one-dimensional (1D) structures, and CPs 2-4 and 5-8 are isostructural, respectively. In 1-4, the 2,4-DCB anions bridge the Ln(III) ions to form a 1D chain. In 5-8, six 2,4-DCB anions link two Ln(III) ions into a binuclear Ln(2)(2,4-DCB)(6) unit, and the Ln(2)(2,4-DCB)(6) units are further connected by the 4,4′-bpy co-ligands to generate a 1D chain. The photoluminescent and magnetic properties of 1-8 were investigated.

Welcome to talk about 50-84-0, If you have any questions, you can contact Zhang, JW; Wang, CR; Liu, WH; Xu, S; Liu, BQ or send Email.. COA of Formula: C7H4Cl2O2

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Name: 2,4-Dichlorobenzoic acid. I found the field of Chemistry very interesting. Saw the article Diastereoselective and Reversed Regioselective Annulations of N-Alkyl Anilines to Julolidines and Lilolidines published in 2020, Reprint Addresses Jana, CK (corresponding author), Indian Inst Technol Guwahati, Dept Chem, Gauhati 780139, Assam, India.. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid.

A three-component annulation reaction of N-alkyl anilines, cyclic 1,3-dicarbonyl compounds, and aryl aldehydes to julolidines and lilolidines is reported. The 6 pi-electrocyclization enabled the annulation to proceed with reversed regioselectivity as compared with the annulation that occurs in the Povarov reaction. Both cyclic and acyclic N-alkyl anilines participated in the reaction to provide a wide range of julolidines and lilolidines as the single regio- and diastereoisomers in good to excellent yields.

Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.. Name: 2,4-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

COA of Formula: C7H4Cl2O2. Authors Anastassiadou, M; Bernasconi, G; Brancato, A; Cabrera, LC; Ferreira, L; Greco, L; Jarrah, S; Kazocina, A; Leuschner, R; Magrans, JO; Miron, I; Nave, S; Pedersen, R; Reich, H; Rojas, A; Sacchi, A; Santos, M; Scarlato, AP; Theobald, A; Vagenende, B; Verani, A in EUROPEAN FOOD SAFETY AUTHORITY-EFSA published article about in [Anastassiadou, Maria; Bernasconi, Giovanni; Brancato, Alba; Cabrera, Luis Carrasco; Ferreira, Lucien; Greco, Luna; Jarrah, Samira; Kazocina, Aija; Leuschner, Renata; Magrans, Jose Oriol; Miron, Ileana; Nave, Stefanie; Pedersen, Ragnor; Reich, Hermine; Rojas, Alejandro; Sacchi, Angela; Santos, Miguel; Scarlato, Alessia Pia; Theobald, Anne; Vagenende, Benedicte; Verani, Alessia] European Food Safety Author EFSA, Parma, Italy in 2021, Cited 4. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0

The applicant Syngenta Crop Protection AG submitted a request to the competent national authority in Finland to evaluate the confirmatory data that were identified for propiconazole in the framework of the MRL review under Article 12 of Regulation (EC) No 396/2005 as not available. Following the decision on the non-renewal of the approval of propiconazole and the decision to lower the maximum residue levels (MRLs) for propiconazole to the limit of quantification (LOQ) for all commodities, the data gaps identified in the MRL review are no longer relevant. EFSA summarised some new studies on the toxicological profile of propiconazole metabolites CGA91305, SYN547889 and NOA436613, which were assessed by the rapporteur Member State. Overall, the available information is not sufficient to characterise the toxicological profile of metabolites convertible to 2,4-dichlorobenzoic acid as data gaps still exist for SYN547889, NOA436613, CGA118244, CGA118245, CGA91304 and CGA91305. (C) 2021 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority.

COA of Formula: C7H4Cl2O2. Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Quality Control of 2,4-Dichlorobenzoic acid. Recently I am researching about C-H AMINATION; CARBON-NITROGEN BONDS; 1-NAPHTHYLAMINE DERIVATIVES; 8-AMINOQUINOLINE AMIDES; C5-H PHOSPHONATION; ARYL HALIDES; ACTIVATION; QUINOLINES; STRATEGY; SCOPE, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21102134, 21172200]. Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Ma, YY; Shi, YQ; Yang, F; Wu, YS; Wu, YJ. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid

A practical and efficient protocol for Ag/Ru-cocatalyzed regioselective C-H amination of 8-hydroxyquinoline esters with pyrazoles was developed, This reaction proceeded smoothly via a photoredox-mediated direct C-H/N-H oxidative coupling process. The remarkable features of this reaction include the wide substrate scope, mild reaction conditions and high regioselectivity at the C4 site of the quinolinyl moiety. (C) 2019 Elsevier Ltd. All rights reserved.

Quality Control of 2,4-Dichlorobenzoic acid. Welcome to talk about 50-84-0, If you have any questions, you can contact Ma, YY; Shi, YQ; Yang, F; Wu, YS; Wu, YJ or send Email.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recently I am researching about THERMAL-DECOMPOSITION KINETICS; ORGANIC FRAMEWORKS; CRYSTAL-STRUCTURE; BUILDING UNITS; COMPLEXES; IONS; ACID; 3D; EUROPIUM(III); TERBIUM(III), Saw an article supported by the Education Baureau of Liaoning Province [LQ2017011]; Natural Science Foundation of Liaoning ProvinceNatural Science Foundation of Liaoning Province [2019-ZD-0495]. Published in ELSEVIER SCIENCE SA in LAUSANNE ,Authors: Zhang, JW; Wang, CR; Liu, WH; Xu, S; Liu, BQ. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid. Application In Synthesis of 2,4-Dichlorobenzoic acid

Ln(NO3)(3)center dot nH(2)O reacted with 2,4-dichlorobenzoic acid (2,4-HDCB) and NaOH under solvothermal conditions of water and ethanol to yield four lanthanide-organic coordination polymers (CPs) [Eu(2,4-DCB)(3)(CH3CH2OH)(2)] (1) and [Ln(2,4-DCB)(3)(H2O)] [Ln = Gd (2), Tb (3), Dy (4)]. The second ligand 4,4′-bipyridine (4,4′-bpy) was introduced into the above reaction systems to provide four new lanthanide-organic CPs [Ln(2)(2,4-DCB)(6)(4,4′-bpy)(H2O)(2)] [Ln = Eu (5), Gd (6), Tb (7), Dy (8)]. Single-crystal and powder X-ray diffraction analyses reveal that CPs 1 and 2 possess similar one-dimensional (1D) structures, and CPs 2-4 and 5-8 are isostructural, respectively. In 1-4, the 2,4-DCB anions bridge the Ln(III) ions to form a 1D chain. In 5-8, six 2,4-DCB anions link two Ln(III) ions into a binuclear Ln(2)(2,4-DCB)(6) unit, and the Ln(2)(2,4-DCB)(6) units are further connected by the 4,4′-bpy co-ligands to generate a 1D chain. The photoluminescent and magnetic properties of 1-8 were investigated.

Application In Synthesis of 2,4-Dichlorobenzoic acid. Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

An article 2,4-Dichloro-5-[(N-aryl/alkyl)sulfamoyl]benzoic Acid Derivatives: In Vitro Antidiabetic Activity, Molecular Modeling and In silico ADMET Screening WOS:000458408600007 published article about GLUCOSIDASE INHIBITORY-ACTIVITY; ALPHA-GLUCOSIDASE; BIOLOGICAL EVALUATION; BENZOTHIAZOLE DERIVATIVES; SULFONAMIDE; DOCKING; AMYLASE; BENZENESULFONAMIDE; AGENTS; POTENT in [Thakral, Samridhi; Singh, Vikramjeet] Guru Jambheshwar Univ Sci & Technol, Dept Pharmaceut Sci, Hisar 125001, Haryana, India in 2019, Cited 55. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0. Recommanded Product: 50-84-0

Background: Postprandial hyperglycemia can be reduced by inhibiting major carbohydrate hydrolyzing enzymes, such as alpha-glucosidase and alpha-amylase which is an effective approach in both preventing and treating diabetes. Objective: The aim of this study was to synthesize a series of 2,4-dichloro-5-[(N-and/alkyl)sulfamoyl]benzoic acid derivatives and evaluate alpha-glucosidase and alpha-amylase inhibitory activity along with molecular docking and in silico ADMET property analysis. Method: Chlorosulfonation of 2,4-dichloro benzoic acid followed by reaction with corresponding anilines/amines yielded 2,4-dichloro-5-[(N-aryl/alkyl)sulfamoyl]benzoic acid derivatives. For evaluating their antidiabetic potential alpha-glucosidase and alpha-amylase inhibitory assays were carried out. In silico molecular docking studies of these compounds were performed with respect to these enzymes and a computational study was also carried out to predict the drug-likeness and ADMET properties of the title compounds. Results: Compound 3c (2,4-clichloro-5-[(2-nitrophenyl)sulfamoyl]benzoic acid) was found to be highly active having 3 fold inhibitory potential against alpha-amylase and 5 times inhibitory activity against alpha-glucosidase in comparison to standard drug acarbose. Conclusion: Most of the synthesized compounds were highly potent or equipotent to standard drug acarbose for inhibitory potential against alpha-glucosidase and alpha-amylase enzyme and hence this may indicate their antidiabetic activity. The docking study revealed that these compounds interact with active site of enzyme through hydrogen bonding and different pi interactions.

Welcome to talk about 50-84-0, If you have any questions, you can contact Thakral, S; Singh, V or send Email.. Recommanded Product: 50-84-0

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Product Details of 50-84-0. Xi, Y; Yang, XH; Zhang, HY; Liu, HH; Watson, P; Yang, FF in [Xi, Yue; Yang, Xianhai; Zhang, Hongyu; Liu, Huihui] Nanjing Univ Sci & Technol, Sch Environm & Biol Engn, Jiangsu Key Lab Chem Pollut Control & Resources R, Nanjing 210094, Peoples R China; [Watson, Peter; Yang, Feifei] Univ Connecticut, Dept Civil & Environm Engn, Storrs, CT 06268 USA published Binding interactions of halo-benzoic acids, halo-benzenesulfonic acids and halo-phenylboronic acids with human transthyretin in 2020, Cited 75. The Name is 2,4-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-84-0.

The anionic form-dependent binding interaction of halo-phenolic substances with human transthyretin (hTTR) has been observed previously. This indicates that ionizable compounds should be the primary focus in screening potential hTTR disruptors. Here, the potential binding potency of halo-benzoic acids, halo-benzenesulfonic acids/sulfates and halo-phenylboronic acids with hTTR was determined and analyzed by competitive fluorescence displacement assay integrated with computational methods. The laboratorial results indicated that the three test groups of model compounds exhibited a distinct binding affinity to hTTR. All the tested halo-phenylboronic acids, some of the tested halo-benzoic acids and halo-benzenesulfonic acids/sulfates were shown to be inactive with hTTR Other halo-benzoic acids and halo-benzenesulfonic acids/sulfates were moderate and/or weak hTTR binders. The binding affinity of halo-benzoic acids and halo-benzenesulfonic acids/sulfates with hTTR was similar. The low distribution ability of the model compounds from water to hTTR may be the reason why they exhibited the binding potency observed with hTTR. By introducing other highly hydrophobic compounds, we observed that the binding affinity between compounds and hTTR increased with increasing molecular hydrophobicity. Those results indicated that the highly hydrophobic halo-benzoic acids and halo-benzenesulfonic acids/sulfates may be high-priority hTTR disruptors. Finally, a binary classification model was constructed employing three predictive variables. The sensitivity (S-n), specificity (S-p), predictive accuracy (Q) values of the training set and validation set were >0.83, indicating that the model had good classification performance. Thus, the binary classification model developed here could be used to distinguish whether a given ionizable compound is a potential hTTR binder or not. (C) 2019 Elsevier Ltd. All rights reserved.

Product Details of 50-84-0. Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

I found the field of Agriculture very interesting. Saw the article Non-food bioactive natural forest products as insecticide candidates: Preparation, biological evaluation and molecular docking studies of novel N-(1,3-thiazol-2-yl)carboxamides fused (+)-nootkatone from Chamaecyparis nootkatensis [D. Don] Spach published in 2020. Safety of 2,4-Dichlorobenzoic acid, Reprint Addresses Guo, Y; Jin, CY; Yang, RG (corresponding author), Zhengzhou Univ, Sch Pharmaceut Sci, Key Lab Adv Drug Preparat Technol, Minist Educ, Zhengzhou 450001, Henan, Peoples R China.; Jin, CY (corresponding author), Zhengzhou Univ, State Key Lab Esophageal Canc Prevent & Treatment, Zhengzhou 450052, Henan, Peoples R China.. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid

(+)-Nootkatone, a non-food bioactive natural bicyclic sesquiterpene ketone, is isolated from Chamaecyparis nootkatensis [D. Don] Spach as a renewable forest resource. In continuation of our effort to develop synthetic natural derived insecticides from non-food bioactive products, a small library of thirty N-(1,3- thiazol-2-yl) carboxamides fused (+)-nootkatone was prepared by molecular hybridization and characterized by H-1/C-13 NMR, HR-MS, and IR spectroscopy. Their insecticidal activities against Mythimna separata Walker and Plutella xylostella Linnaeus were evaluated. Compounds B6, B7, B9, B19-21 and B24 showed better insecticidal activity against M. separata than the botanical insecticide azadirachtin, and their LC50 values ranged from 0.55 -0.68 mg/mL. Particularly, compound B9 exhibited 1.87-fold more pronounced insecticidal activity against M. separata than azadirachtin. The insecticidal activity of B21 against P. xylostella was 1.37-fold of that of azadirachtin. Through acetylcholinesterase (AChE) inhibitory activity and molecular docking studies, AChE may be the insecticidal target of B9 against M. separata. In addition, three pronounced compounds B9, B21 and B24 exhibited low hemolytic and cytotoxic activities on normal mammalian cells. These findings will give insights into the further development of (+)-nootkatone derivatives as potentially synthetic natural derived insecticides for pest management.

Bye, fridends, I hope you can learn more about C7H4Cl2O2, If you have any questions, you can browse other blog as well. See you lster.. Safety of 2,4-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recommanded Product: 2,4-Dichlorobenzoic acid. I found the field of Agriculture; Chemistry; Food Science & Technology very interesting. Saw the article Discovery of Novel Piperidinylthiazole Derivatives As Broad-Spectrum Fungicidal Candidates published in 2019, Reprint Addresses Zhao, B; Fan, ZJ (corresponding author), Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.; Fan, ZJ (corresponding author), Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300071, Peoples R China.. The CAS is 50-84-0. Through research, I have a further understanding and discovery of 2,4-Dichlorobenzoic acid.

Oxathiapiprolin is one of the best active fungicides discovered for oomycetes control. To develop a fungicide candidate with a broad spectrum of activity, 22 new piperidinylthiazole derivatives were designed and synthesized. Compound 51 showed the best activity against Pseudoperonospora cubensis (Berk. et Curt.) Rostov and Phytophthora infestans in vivo with 100% and 80% of inhibition, respectively, at 1 mg/L, and 72.87% of field efficacy against P. cubensis at 1 g ai/667 m(2) validated these results. Compound 5i exhibited a broad spectrum of excellent activity against Sclerotinia sclerotiorum with EC50 = 0.30 mg/ L (>10 times more active than oxathiapiprolin and azoxystrobin in vitro), good activity against Botrytis cinerea, Cercospora arachidicola, and Gibberella zeae with EC50 of 14.54, 5.57, and 14.03 mg/L in vitro and against P. cubensis and P. infestans with 60% and 30% inhibition rates, respectively, at 1 mg/L in vivo. Mode of action studies by RNA sequencing analysis discovered oxysterol-binding protein (OSBP), chitin synthase (CHS1), and (1,3)-beta-glucan synthase (FKS2) as the potent target of 5i against S. sclerotiorum. Quenching studies validated that OSBP was the same target of both 5i and oxathiapiprolin; it was quenched by both of them. Our studies discovered isothiazole-containing piperidinylthiazole as an OSBP target-based novel lead for fungicide development.

Welcome to talk about 50-84-0, If you have any questions, you can contact Wu, QF; Zhao, B; Fan, ZJ; Guo, XF; Yang, DY; Zhang, NL; Yu, B; Zhou, S; Zhao, JB; Chen, F or send Email.. Recommanded Product: 2,4-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics