Category: 50-30-6

Hu, FP; Cui, XF; Ban, ZH; Lu, GP; Luo, N; Huang, GS in [Hu, Fangpeng; Cui, Xinfeng; Ban, Zihui; Lu, Guoqiang; Luo, Nan; Huang, Guosheng] Lanzhou Univ, State Key Lab Appl Organ Chem, Key Lab Nonferrous Met Chem & Resources Utilizat, Dept Chem, Lanzhou 730000, Gansu, Peoples R China published Synthesis of quinazolin-4(1H)-ones via amination and annulation of amidines and benzamides in 2019.0, Cited 65.0. Application In Synthesis of 2,6-Dichlorobenzoic acid. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Quinazolinones have broad applications in the biological, pharmaceutical and material fields. Studies on the synthesis of these compounds are therefore widely conducted. Herein, a novel and highly efficient copper-mediated tandem C(sp(2))-H amination and annulation of benzamides and amidines for the synthesis of quinazolin-4(1H)-ones is proposed. This synthetic route can be useful for the construction of quinazolin-4(1H)-one frameworks.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Hu, FP; Cui, XF; Ban, ZH; Lu, GP; Luo, N; Huang, GS or concate me.. Application In Synthesis of 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Authors Yu, CL; Devlin, JF; Bi, EP in PERGAMON-ELSEVIER SCIENCE LTD published article about SURFACE COMPLEXATION; MINERAL SURFACES; ORGANIC-ACIDS; LINEAR ALKYLBENZENESULFONATES; PHARMACEUTICAL COMPOUNDS; COMPETITIVE SORPTION; CARBON NANOTUBES; PHTHALIC-ACID; IRON-OXIDES; ATR-FTIR in [Yu, Chenglong; Bi, Erping] China Univ Geosci Beijing, Sch Water Resources & Environm, 29 Xueyuan Rd, Beijing 100083, Peoples R China; [Yu, Chenglong; Bi, Erping] China Univ Geosci Beijing, MOE Key Lab Groundwater Circulat & Environm Evolu, 29 Xueyuan Rd, Beijing 100083, Peoples R China; [Devlin, J. F.] Univ Kansas, Dept Geol, Lindley Hall,1475 Jayhawk Blvd, Lawrence, KS 66049 USA in 2019.0, Cited 45.0. Safety of 2,6-Dichlorobenzoic acid. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6

Adsorption of a diverse set of chemicals onto goethite was evaluated by column chromatography. The pH of the effluents was 4.7-5.2. Van der Waals forces dominate the exothermic adsorption of 8 nonpolar compounds (e.g., PAHs and chlorobenzenes). H-bonding is responsible for the adsorption of 32 mono-carboxylic acids (i.e., benzoic acids, naphthoic acids and acidic pharmaceuticals) and their adsorption tends to be endothermic. Steric effects significantly decreased the bonding of monocarboxylic acids with ortho-substitutions. Exothermic adsorption of 10 monophenols is controlled by weak H-bonding. Bonding of these 50 solutes onto goethite is totally reversible. In contrast, inner-sphere complexation of phthalic acid and chlortetracycline with goethite occurred according to their low desorption ratio (1.1%-54.4%). Polyparameter linear free energy relationship (PP-LFER) models were established to provide acceptable fitting results of the goethite-solute distribution coefficients (RMSE = 0.32 and 0.30 at 25 degrees C and 5 degrees C, respectively). It is worthy to note that steric effects must be considered to get a better prediction for compounds with ortho-substitutions. (C) 2018 Elsevier Ltd. All rights reserved.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Yu, CL; Devlin, JF; Bi, EP or concate me.. Safety of 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

SDS of cas: 50-30-6. I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article Structural Aspects of the Ortho Chloro- and Fluoro- Substituted Benzoic Acids: Implications on Chemical Properties published in 2020.0, Reprint Addresses Ildiz, GO (corresponding author), Univ Coimbra, Dept Chem, CQC, P-3004535 Coimbra, Portugal.; Ildiz, GO (corresponding author), Istanbul Kultur Univ, Fac Sci & Letters, Dept Phys, Atakoy Campus, TR-34156 Istanbul, Turkey.. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid.

This article presents a detailed comprehensive investigation of the ortho fluoro- and chloro- substituted benzoic acids both, as isolated molecules and in the crystalline phase. Quantum chemical calculations performed within the density functional theory (DFT) formalism are used to investigate the potential energy landscapes of the molecules, taking into special consideration the effects of the interactions between the carboxylic group and the ortho halogen substituents, as well as the nature of these later on the structure and properties of the investigated systems. The structures of the relevant conformers of the molecules are discussed in comparative terms, and used to rationalize experimental data obtained for the compounds in the gas phase and isolated in low-temperature inert matrices. The UV-induced photofragmentation reactions of two of the compounds isolated in cryogenic inert matrices were studied as illustrative cases. The structures of the crystals reported previously in the literature are revisited and discussed also in a comparative basis. Particular emphasis is given to the analysis of the intermolecular interactions in the different crystals, using Hirshfeld surface analysis, the CE-B3LYP energy decomposition model and the HOMA index, and to their correlation with thermodynamic data.

SDS of cas: 50-30-6. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Ildiz, GO; Fausto, R or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Computed Properties of C7H4Cl2O2. Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH in [Liu, Yu; Zhang, Sheng; Li, Changyou; Shi, Xiaohong; Zhao, Shengnan; Sun, Biao; Zhu, Yonghua] Inner Mongolia Agr Univ, Water Conservancy & Civil Engn Coll, Hohhot 010018, Peoples R China published A modified QWASI model for fate and transport modeling of Zn and Pb in a shallow lake during the ice-free period in 2019.0, Cited 35.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Heavy metal pollution in lakes is becoming increasingly of interest to researchers. Because heavy metals have high mobility and do not degrade, they migrate easily between different environmental mediums through processes such as suspended solids deposition, sediment resuspension, and diffusion, among others. These processes are particularly pronounced in shallow lakes since the hydrodynamism is higher in bodies of water with minimal depth. Lake Ulansuhai a typical shallow lake in the Hetao irrigation district in Inner Mongolia-also experiences intense sandstorm activity, which compounds the suspended solids exchange intensity between water and sediment, strengthening the migration of heavy metals in the lake system. This study examines the fate and transport of two heavy metals-Zn and Pb-within this lake, using a field experiment to determine the flux of sediment re-suspension and deposition and a laboratory experiment to modify the QWASI model for shallow bodies of water. The aguivalence and mass balance approaches were used to develop this modified QWASI model. The margins of error between the modeled and the measured average concentrations of Zn and Pb in water were 5.0%-30.6% and 5.8%-29.5%, respectively, and in sediment were 0.3%-4.9% and 0.9-5.5%, respectively. These results suggest that the modified QWASI model developed here could indeed be used to more accurately represent the fate and transport of Zn and Pb during the icefree period of a shallow lake. (C) 2013 Elsevier B.V. All rights reserved.

Computed Properties of C7H4Cl2O2. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Name: 2,6-Dichlorobenzoic acid. Recently I am researching about SP STRAIN HBP1; HYDROLYTIC DEHALOGENATION; DEGRADATION; BAM; DICHLOBENIL; GENES; ACID; 4-CHLOROBENZOATE; 3-CHLOROBENZOATE; 2,3-DIOXYGENASE, Saw an article supported by the KU Leuven Cl project [C14/15/043]; BELSPO IAP-project mu-manager [P7/25]; FWOFWO [12Q0215N, 12Q0218N]; Swiss National Science Foundation (SNSF)Swiss National Science Foundation (SNSF) [206021150638/1]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Raes, B; Horemans, B; Rentsch, D; T’Syen, J; Ghequire, MGK; De Mot, R; Wattiez, R; Kohler, HPE; Springael, D. The CAS is 50-30-6. Through research, I have a further understanding and discovery of 2,6-Dichlorobenzoic acid

2,6-Dichlorobenzamide (BAM) is a major groundwater micropollutant posing problems for drinking water treatment plants (DWTPs) that depend on groundwater intake. Aminobacter sp. MSH1 uses BAM as the sole source of carbon, nitrogen, and energy and is considered a prime biocatalyst for groundwater bioremediation in DWTPs. Its use in bioremediation requires knowledge of its BAM-catabolic pathway, which is currently restricted to the amidase BbdA converting BAM into 2,6-dichlorobenzoic acid (2,6-DCBA) and the monooxygenase BbdD transforming 2,6-DCBA into 2,6-dichloro-3-hydroxybenzoic acid. Here, we show that the 2,6-DCBA catabolic pathway is unique and differs substantially from catabolism of other chlorobenzoates. BbdD catalyzes a second hydroxylation, forming 2,6-dichloro-3,5-dihydroxybenzoic acid. Subsequently, glutathione-dependent dehalogenases (BbdI and BbdE) catalyze the thiolytic removal of the first chlorine. The remaining chlorine is then removed hydrolytically by a dehalogenase of the alpha/beta hydrolase superfamily (BbdC). BbdC is the first enzyme in that superfamily associated with dehalogenation of chlorinated aromatics and appears to represent a new subtype within the alpha/beta hydrolase dehalogenases. The activity of BbdC yields a unique trihydroxylated aromatic intermediate for ring cleavage that is performed by an extradiol dioxygenase (BbdF) producing 2,4,6-trioxoheptanedioic acid, which is likely converted to Krebs cycle intermediates by BbdG.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Raes, B; Horemans, B; Rentsch, D; T’Syen, J; Ghequire, MGK; De Mot, R; Wattiez, R; Kohler, HPE; Springael, D or concate me.. Name: 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

COA of Formula: C7H4Cl2O2. Authors Chen, JN; Wu, XK; Lu, CH; Li, X in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Chen, Ji-Ning; Lu, Chun-Hua; Li, Xun] Shandong Univ, Cheeloo Coll Med, Sch Pharmaceut Sci, Minist Educ,Key Lab Chem & Chem Biol, Jinan 250012, Shandong, Peoples R China; [Li, Xun] Shandong First Med Univ & Shandong Acad Med Sci, Inst Mat Med, Jinan 250002, Shandong, Peoples R China; [Wu, Xing-Kang] Shanxi Univ, Modern Res Ctr Tradit Chinese, Taiyuan 030006, Shanxi, Peoples R China in 2021.0, Cited 19.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6

Unlike other DNA topoisomerase II (topo II) inhibitors, our recently identified acridone derivative E17 exerted strong cytotoxic activity by inhibiting topo II without causing topo II degradation and DNA damage, which promoted us to explore more analogues of E17 by expanding its chemical diversification and enrich the structure-activity relationship (SAR) outcomes of acridone-oriented chemotypes. To achieve this goal, 42 novel acridone derivatives were synthesized and evaluated for their antiproliferative efficacies. SAR investigations revealed that orientation and spatial topology of R-3 substituents make greater contributions to the bioactivity, exemplified by compounds E24, E25 and E27, which has provided valuable information for guiding further development of acridone derivatives as promising drug candidates.

COA of Formula: C7H4Cl2O2. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Chen, JN; Wu, XK; Lu, CH; Li, X or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Recommanded Product: 2,6-Dichlorobenzoic acid. Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH in [Liu, Yu; Zhang, Sheng; Li, Changyou; Shi, Xiaohong; Zhao, Shengnan; Sun, Biao; Zhu, Yonghua] Inner Mongolia Agr Univ, Water Conservancy & Civil Engn Coll, Hohhot 010018, Peoples R China published A modified QWASI model for fate and transport modeling of Zn and Pb in a shallow lake during the ice-free period in 2019.0, Cited 35.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Heavy metal pollution in lakes is becoming increasingly of interest to researchers. Because heavy metals have high mobility and do not degrade, they migrate easily between different environmental mediums through processes such as suspended solids deposition, sediment resuspension, and diffusion, among others. These processes are particularly pronounced in shallow lakes since the hydrodynamism is higher in bodies of water with minimal depth. Lake Ulansuhai a typical shallow lake in the Hetao irrigation district in Inner Mongolia-also experiences intense sandstorm activity, which compounds the suspended solids exchange intensity between water and sediment, strengthening the migration of heavy metals in the lake system. This study examines the fate and transport of two heavy metals-Zn and Pb-within this lake, using a field experiment to determine the flux of sediment re-suspension and deposition and a laboratory experiment to modify the QWASI model for shallow bodies of water. The aguivalence and mass balance approaches were used to develop this modified QWASI model. The margins of error between the modeled and the measured average concentrations of Zn and Pb in water were 5.0%-30.6% and 5.8%-29.5%, respectively, and in sediment were 0.3%-4.9% and 0.9-5.5%, respectively. These results suggest that the modified QWASI model developed here could indeed be used to more accurately represent the fate and transport of Zn and Pb during the icefree period of a shallow lake. (C) 2013 Elsevier B.V. All rights reserved.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Liu, Y; Zhang, S; Li, CY; Shi, XH; Zhao, SN; Sun, B; Zhu, YH or concate me.. Recommanded Product: 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocks. Authors Fogel, JM; Bonsall, D; Cummings, V; Bowden, R; Golubchik, T; de Cesare, M; Wilson, EA; Gamble, T; del Rio, C; Batey, DS; Mayer, KH; Farley, JE; Hughes, JP; Remien, RH; Beyrer, C; Fraser, C; Eshleman, SH in OXFORD UNIV PRESS published article about in [Fogel, Jessica M.; Cummings, Vanessa; Eshleman, Susan H.] Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA; [Bonsall, David; Golubchik, Tanya; Fraser, Christophe] Univ Oxford, Big Data Inst, Nuffield Dept Med, Oxford, England; [Bowden, Rory; de Cesare, Mariateresa] Univ Oxford, Wellcome Ctr Human Genet, Oxford, England; [Wilson, Ethan A.] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA; [Gamble, Theresa] FHI 360, Durham, NC USA; [del Rio, Carlos] Emory Univ, Hubert Dept Global Hlth, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA; [del Rio, Carlos] Emory Univ, Sch Med, Dept Med, Atlanta, GA USA; [Batey, D. Scott] Univ Alabama Birmingham, Dept Social Work, Birmingham, AL USA; [Mayer, Kenneth H.] Harvard Med Sch, Dept Med, Boston, MA 02115 USA; [Mayer, Kenneth H.] Fenway Inst, Boston, MA USA; [Farley, Jason E.] Johns Hopkins Univ, REACH Initiat, Sch Nursing, Baltimore, MD USA; [Hughes, James P.] Univ Washington, Dept Biostat, Seattle, WA 98195 USA; [Remien, Robert H.] NY State Psychiat Inst, HIV Ctr Clin & Behav Studies, New York, NY USA; [Remien, Robert H.] Columbia Univ, Dept Psychiat, New York, NY USA; [Beyrer, Chris] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA in 2020.0, Cited 17.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6

Objectives: To evaluate the performance of a high-throughput research assay for HIV drug resistance testing based on whole genome next-generation sequencing (NGS) that also quantifies HIV viral Load. Methods: Plasma samples (n = 145) were obtained from HIV-positive MSM (HPTN 078). Samples were analysed using clinical assays (the ViroSeq HIV-1 Genotyping System and the Abbott RealTime HIV-1 Viral Load assay) and a research assay based on whole-genome NGS (veSEQ-HIV). Results: HIV protease and reverse transcriptase sequences (n =142) and integrase sequences (n =138) were obtained using ViroSeq. Sequences from all three regions were obtained for 100 (70.4%) of the 142 samples using veSEQ-HIV; results were obtained more frequently for samples with higher viral Loads (93.5% for 93 samples with >5000 copies/mL; 50.0% for 26 samples with 1000-5000 copies/mL; 0% for 23 samples with <1000 copies/mL). For samples with results from both methods, drug resistance mutations (DRMs) were detected in 33 samples using ViroSeq and 42 samples using veSEQ-HIV (detection threshold: 5.0%). Overall, 146 major DRMs were detected; 107 were detected by both methods, 37 were detected by veSEQ-HIV only (frequency range: 5.0%-30.6%) and two were detected by ViroSeq only. HIV viral Loads estimated by veSEQ-HIV strongly correlated with results from the Abbott RealTime Viral Load assay (R-2 = 0.85; n = 142). Conclusions: The NGS-based veSEQ-HIV method provided results for most samples with higher viral Loads, was accurate for detecting major DRMs, and detected mutations at Lower Levels compared with a method based on population sequencing. The veSEQ-HIV method also provided HIV viral Load data. Category: chlorides-buliding-blocks. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Fogel, JM; Bonsall, D; Cummings, V; Bowden, R; Golubchik, T; de Cesare, M; Wilson, EA; Gamble, T; del Rio, C; Batey, DS; Mayer, KH; Farley, JE; Hughes, JP; Remien, RH; Beyrer, C; Fraser, C; Eshleman, SH or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Computed Properties of C7H4Cl2O2. In 2019.0 NICOTINE TOB RES published article about NICOTINE DELIVERY-SYSTEMS; UNITED-STATES; SOCIAL-CLASS; HEALTH; DISEASE; ADULTS; TRENDS; INEQUALITIES; ESTIMATORS; AWARENESS in [Friedman, Abigail S.] Yale Sch Publ Hlth, Dept Hlth Policy & Management, 60 Coll St,Rm 303, New Haven, CT 06520 USA; [Horn, Samantha J. L.] Northwestern Univ, Global Poverty Res Lab, Evanston, IL USA in 2019.0, Cited 38.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

Introduction Socioeconomic disparities have been established for conventional cigarette use, but not for electronic cigarettes. This study estimates socioeconomic gradients in exclusive use of conventional cigarettes, electronic cigarettes, and dual use (ie, use of both products) among adults in the United States. Methods Analyses consider nationally representative data on 25- to 54-year-old respondents to the 2014-2016 National Health Interview Surveys (N = 50306). Demographically adjusted seemingly unrelated regression models estimate how two socioeconomic status measures-respondent education and household income-relate to current exclusive use of conventional cigarettes, electronic cigarettes, and dual use. Results Conventional cigarette use exhibits negative education and income gradients, consistent with existing research: -12.9 percentage points (confidence interval [CI]: -14.0, -11.8) if college educated, and -9.5 percentage points (CI: -10.9, -8.1) if household income exceeds 400% of the federal poverty level. These gradients are flatter for dual use (-1.4 [CI: -1.8, -0.9] and -1.9 [CI: -2.5, -1.2]), and statistically insignificant for electronic cigarette use (-0.03 [CI: -0.5, 0.4] and -0.3 [CI: -0.8, -0.2]). Limiting the sample to ever-smokers, higher education is associated with a 0.9 percentage point increase in likelihood of exclusive electronic cigarette use at interview (CI: 0.0, 1.9). Conclusions Education and income gradients in exclusive electronic cigarette use are small and statistically insignificant, contrasting with strong negative gradients in exclusive conventional cigarette use. Furthermore, more educated smokers are more likely to switch to exclusive e-cigarette use than less educated smokers. Such differential switching may exacerbate socioeconomic disparities in smoking-related morbidity and mortality, but lower the burden of tobacco-related disease. Implications Research has not yet established whether socioeconomic disparities in electronic cigarette (e-cigarette) use resemble those observed for conventional cigarettes. This article uses nationally representative data on US adults aged 25-54 to estimate income and education gradients in exclusive use of conventional cigarettes, e-cigarettes, and dual use. Both gradients are steep and negative for conventional cigarette use, but flat and statistically insignificant for e-cigarette use. Repeating the analysis among ever-smokers indicates that more educated smokers are more likely to transition toward exclusive e-cigarette use than less educated smokers. Such differential substitution may exacerbate disparities in smoking-related morbidity and mortality.

Computed Properties of C7H4Cl2O2. About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Friedman, AS; Horn, SJL or concate me.

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics

Name: 2,6-Dichlorobenzoic acid. Liu, J; Wang, SM; Qin, HL in [Liu, Jing; Qin, Hua-Li] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 205 Luoshi Rd, Wuhan 430070, Peoples R China; [Wang, Shi-Meng] Wuchang Univ Technol, Sch Life Sci, Wuhan 430223, Peoples R China published Room temperature clickable coupling electron deficient amines with sterically hindered carboxylic acids for the construction of amides in 2020.0, Cited 86.0. The Name is 2,6-Dichlorobenzoic acid. Through research, I have a further understanding and discovery of 50-30-6.

A method for the synthesis of difficult-to-access amides was developed through the coupling of sterically hindered carboxylic acids and electron deficient amines via SO2F2-mediated dehydration. The method feathers with broad substrate scope, mild conditions, excellent functional group compatibility and high yields. (C) 2020 Elsevier Ltd. All rights reserved.

About 2,6-Dichlorobenzoic acid, If you have any questions, you can contact Liu, J; Wang, SM; Qin, HL or concate me.. Name: 2,6-Dichlorobenzoic acid

Reference:
Chloride – Wikipedia,
,Chlorides – an overview | ScienceDirect Topics