Category: 4569-86-2

Yao, Si; Zheng, Yunman; Jiang, Lijun; Xie, Chen; Wu, Fengshou; Huang, Chi; Zhang, Xiong; Wong, Ka-Leung; Li, Zaoying; Wang, Kai published an article in 2018, the title of the article was Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study.Synthetic Route of 4569-86-2 And the article contains the following content:

A methylene violet 3RAX-conjugated porphyrin has been designed and synthesized as a potential photosensitizer in photodynamic therapy because of its high DNA binding constant and the efficacy in inhibiting cancer cells with subcellular localization. At 400μM, the DNA photocleavage activities of compound 1 and2 were 80% and 20%, resp. The results fromphotophys. studies and cell experiments suggest porphyrin-methylene violet 3RAX conjugate could be developed as potential photosensitizers for mitochondrial targeting action in PDT. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Synthetic Route of 4569-86-2

The Article related to methylene violet 3rax dna photocleavage photosensitizer photodynamic therapy, Placeholder for records without volume info and other aspects.Synthetic Route of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 21, 2021, Jenkins, Samir; Griffin, Robert published a patent.Quality Control of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the patent was Photosensitizer conjugated nanoparticles for radiotherapy enhancement. And the patent contained the following:

Among the various aspects of the present disclosure is the provision of compositions and methods for targeted treatment of cancers or neoplasms. In particular, the present disclosure is directed to a photodynamic system comprising a nanoparticle conjugated to a photosensitizer that can be activated by an excitation source such as ionizing radiation or other forms of electromagnetic energy. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Quality Control of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to photosensitizer conjugated nanoparticle radiotherapy, Pharmaceuticals: Formulation and Compounding and other aspects.Quality Control of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 24, 2007, Hasan, Tayyaba; Nau, Gerald J. published a patent.COA of Formula: C22H23ClN4 The title of the patent was Photoactivatable antimicrobial agents. And the patent contained the following:

Photoactivatable antimicrobial compounds and methods for the use thereof in the treatment of infections are provided. Photosensitizers, drugs, and targeting moieties are conjugated using linkers which comprise an enzyme cleavage site for an enzyme of a pathogen. The enzyme cleavage site comprises a cephalosporin, penicillin, penem, etc. The targeting moiety may be directed to a pathogen or a host cell infected with a pathogen. Photosensitizers are present in an amount sufficient to quench photoactivation of the photosensitizers. An example is provided of the preparation of a cephalosporanic acid-photosensitizer prodrug which is cleaved in the presence of β-lactamase from Enterobacter cloacae. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).COA of Formula: C22H23ClN4

The Article related to photoactivatable antimicrobial prodrug, Pharmaceuticals: Formulation and Compounding and other aspects.COA of Formula: C22H23ClN4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dow, Wei-Ping; Li, Chih-Chan; Lin, Meng-Wen; Su, Ging-Wen; Huang, Chen-Chia published an article in 2009, the title of the article was Copper Fill of Microvia Using a Thiol-Modified Cu Seed Layer and Various Levelers.Electric Literature of 4569-86-2 And the article contains the following content:

Microvia filling by Cu electroplating was carried out using a plating bath containing a suppressor and a leveler without an accelerator. The required accelerator was adsorbed onto the Cu seed layer of the microvia in a predipping bath before the filling plating. This pretreatment is similar to the self-assembled monolayer of thiol mols. that forms on a Cu surface. The suppressor was poly(ethylene glycol) (PEG), and 5 levelers, namely, Janus green B, diazine black, methylene violet, safranine O, and Alcian blue, were employed to screen for the best plating formula suitable for a plating process in which no accelerator was present in the plating solution The thiol mol. employed in this work was 3-mercapto-1-propanesulfonate (MPS). The electrochem. behaviors of various plating formulas were characterized using a galvanostatic measurement on a Cu electrode at different rotating speeds. The MPS adlayer is transferable onto the surface of the Cu deposit and can be displaced by the PEG-Cl-leveler. The displacement rate depends on the mol. structure of the added leveler. This plating process has the potential to greatly reduce the plating time of microvia filling. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Electric Literature of 4569-86-2

The Article related to copper electroplating microvia filling thiol modified seed layer, various leveler copper electroplating thiol modified seed layer, Electrochemistry: Industrial Cathodic Processes and other aspects.Electric Literature of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 31, 2018, Zhang, Yun; Wang, Jing; Zhu, Zifang; Ma, Tao; Chen, Luming published a patent.Related Products of 4569-86-2 The title of the patent was Copper crystal particles having highly preferred orientation and preparation method thereof. And the patent contained the following:

An electroplating Cu layer includes bamboo-like Cu crystal particles having a highly preferred orientation. The bamboo-like Cu crystal particles have a long axis direction and a short axis direction, and the bamboo-like Cu crystal particles have a length of 20 nm to 5 μm in the long axis direction and a length of 20 nm to 2 μm in the short axis direction. A method of preparing the bamboo-like Cu crystal particles is also disclosed. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Related Products of 4569-86-2

The Article related to copper crystal particle preferred orientation preparation electrodeposition, Electrochemistry: Industrial Cathodic Processes and other aspects.Related Products of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 31, 2014, Baranek, Wit; Kopyto, Dorota; Hanke, Michal; Wyrebska, Lucja; Sobolewski, Wieslaw published a patent.SDS of cas: 4569-86-2 The title of the patent was Method for producing cathodic copper. And the patent contained the following:

A method of production of cathodic copper using copper anodes in electrolytes containing copper salt (35 – 55 g/dm3), sulfuric acid (150 – 200 g/dm3), nickel ions (0.01 – 0.05 g/dm3) and chlorine (0.01 – 0.05 g/dm3) with addnl. content of impurity ions up to 20 g/dm3 is described. The bath also contained electrodeposition inhibitors such as hexylmethylene-guanidine polymer and/or choline chloride and/or di-Et safranine together with animal glue and thiourea. The composition of the electrorefining copper bath is described in details. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).SDS of cas: 4569-86-2

The Article related to cathodic copper bath composition electrodeposition electroplating, Electrochemistry: Industrial Cathodic Processes and other aspects.SDS of cas: 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 31, 2009, Lakshmi, P. Baby Sudha; Vardhan, S. V. M.; Ramachandran, D.; Rambabu, C. published an article.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride The title of the article was Use of some basic dyes in the extractive spectrophotometric determination of tranexamic acid. And the article contained the following:

A simple and sensitive spectrophotometric method is developed for the determination of tranexamic acid. It is based on the formation of colored ion-pair complex between the tranexamic acid and basic dyes (methylene blue, methylene violet, and saframin-O) in the aqueous phase at suitable pH extractable into chloroform showing the characteristic absorption maximum at 650, 550, and 520 nm, resp. The method was applied to pharmaceutical formulations. The method was statistically validated and is found to be precise and accurate. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to tranexamic acid determination basic dye spectrophotometry, Pharmaceutical Analysis: Natural Drug Materials and other aspects.Recommanded Product: 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 22, 1999, Moeller, Hinrich; Meinigke, Bernd published a patent.Recommanded Product: 4569-86-2 The title of the patent was Use of phenazinium salts for dyeing keratin fibers. And the patent contained the following:

Phenazinium salts I [R1, R2 = (alkyl- or aryl-substituted) amino; R3, R6 = H, C1-4 alkyl, (alkyl- or aryl-substituted) amino; R4, R5 = H, C1-4 alkyl; R7 = C1-4 alkyl, aryl; X- = anion] are provided as direct hair dyes which produce excellent brilliance and depth of color with many color nuances. The dyes show excellent fastness with little potential for sensitization. Thus, a hair-dyeing cream containing 0.1 weight% Methylene Violet 3RAX, applied to blond hair for 30 min at 30°, produced a beet-red color. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Recommanded Product: 4569-86-2

The Article related to phenazinium hair dye, Essential Oils and Cosmetics: Hair Preparations and other aspects.Recommanded Product: 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 19, 2015, Nakamura, Kimie published a patent.Product Details of 4569-86-2 The title of the patent was Corona treated film staining solution and visual evaluation method using the same. And the patent contained the following:

The solution contains a colorant having quaternary ammonium salt structure which had been removed and a solvent which can dissolve a substrate and is incompatible with water such as hexane, CHCl3, toluene and MEK. An example of the colorant is Methylene Violet 3Rax or Janus Green B. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Product Details of 4569-86-2

The Article related to staining agent colona discharge film methylene violet, Coatings, Inks, and Related Products: General and other aspects.Product Details of 4569-86-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chevalier, Arnaud; Massif, Cedrik; Renard, Pierre-Yves; Romieu, Anthony published an article in 2013, the title of the article was Bioconjugatable Azo-Based Dark-Quencher Dyes: Synthesis and Application to Protease-Activatable Far-Red Fluorescent Probes.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride And the article contains the following content:

The authors describe the efficient synthesis and one-step derivatization of novel, nonfluorescent azo dyes based on the Black Hole Quencher-3 (BHQ-3) scaffold. These dyes were equipped with various reactive and/or bioconjugatable groups (azido, α-iodoacetyl, ketone, terminal alkyne, vicinal diol). The azido derivative is highly reactive in the context of copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions and allowed easy synthetic access to the first water-soluble (sulfonated derivative) and aldehyde-modified BHQ-3 dyes, the direct preparation of which failed by conventional azo-coupling reactions. The aldehyde- and α-iodoacetyl-containing fluorescence quenchers were readily conjugated to aminooxy- and cysteine-containing peptides by the formation of a stable oxime or thioether linkage, resp. Further fluorescent labeling of the resultant peptide conjugates with red- or far-red-emitting rhodamine or cyanine dyes through sequential and/or one-pot bioconjugations, led to novel Foerster resonance energy transfer (FRET) based probes suitable for the in vivo detection and imaging of urokinase plasminogen activator, a key protease in cancer invasion and metastasis. The experimental process involved the reaction of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride(cas: 4569-86-2).Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

The Article related to bioconjugatable azo dark quencher plasminogen activator fluorescent probe, Biochemical Methods: Spectral and Related Methods and other aspects.Application In Synthesis of 3-Amino-7-(diethylamino)-5-phenylphenazin-5-ium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics